Gene Query: ADAM8

Dataset Description Geneva Score
Identification of IL-27 as potent regulator of inflammatory osteolysis associated with vitamin E-blended ultra-high molecular weight polyethylene debris of orthopedic implants 147.9
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 120.59
Control of prostate tumour growth by the long non-coding RNA GHSROS 88.72
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 87.78
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 75.81
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 57.47
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 55.9
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 54.01
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 53.73
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 53.73
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 53.48
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 50.42
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 48.62
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 46.83
Inhibition of TNBC metastasis by Gpx1 45.02
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 41.19
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  40.94
naive T cell heterogeneity after neonatal thymectomy 37.44
RNA-seq of stable and unstable section of human atherosclerotic plaques 36.51
Replicated transcriptome profiling of Normal and Cancerous Prostate Cells [RNA-Seq] 36.32
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 36.26
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq] 36.22
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations 36.22
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 35.81
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 35.65
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 34.82
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 34.74
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 34.49
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 33.11
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 33.11
Fbxo32 mediated gene expression program underlies EMT and metastasis 32.52
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  32.09
Mutational landscape of splicing genes and functional consequences across 33 cancer types 32.05
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 31.24
Transcriptional profiles of normal human mature B cells 28.78
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 28.31
Transcriptome profiling of Normal and Cancerous Prostate Cells 26.74
Evolved Labels of Placental Invasion in Human and Bovine Endometrial Stroma 26.71
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 26.24
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 25.95
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 25.69
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 25.48
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 25.17
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 25.17
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 24.87
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 24.83
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 24.8
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 24.55
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 24.44
MEIS1 regulates hematopoiesis in hPSCs 23.85
FOXD3 is a novel tumor suppressor in lung cancer 23.68
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 23.67
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 23.4
RNAseq of IL-36 stimulated primary human keratinocytes 23.21
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 23.17
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 23.17
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing 22.81
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing [RNA-seq] 22.81
Regulating Interleukin-2 activity with engineered receptor signaling clamps 22.56
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 22.3
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 21.98
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 21.98
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 21.94
Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms 21.43
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 21.36
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 21.28
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 21.28
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 21.23
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 21.03
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 21.03
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 20.96
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 20.95
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 20.89
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 20.63
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 20.23
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 19.97
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 19.64
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 19.34
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 19.34
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 18.96
Gene Expression Profiling of SPOP Knocked Down Cell 18.89
Investigate A2M treatment on human prostate cancer and mouse liver 18.29
Investigate A2M treatment on human prostate cancer xenograft in mice 18.29
Rorc disruption in human FG pancreatic cancer cells 17.68
Gene expression profile of multiple myeloma cell lines treated with CB-5083 17.57
Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation 17.45
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 17.43
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 17.43
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 17.36
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 17.36
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 17.36
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 17.25
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 17.25
Global analysis of alternative splicing regulated by RBM10 17.22
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 16.95
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 16.78
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NfkB-dependent differentiation of AML cells 16.64
Generation and functional characterization of MDSC-like cells 16.64
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 16.61
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 16.42
Stem and effector CD8 T-cells from human cancers 16.28
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 16.27
RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines 16.17
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 16.13
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 16.13
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 15.99
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 15.95
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 15.56
Characterization of Human Pegivirus Infection in Liver Transplantation Recipients 15.52
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 15.47
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 15.37
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 15.02
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 14.9
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 14.85
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 14.69
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 14.63
Paxillin regulates genomic networks in prostate cancer [PC3] 14.6
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 14.43
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 14.2
Effects of rFVIIIFc on human macrophages 14.19
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 14.07
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 13.87
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 13.85
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 13.83
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 13.81
CD86 regulates a pro-survival signal in myeloma cells 13.79
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 13.78
Intrahepatic MAIT cell gene expression revealed by RNA-seq 13.76
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 13.57
Transcriptomes of human monocytes and monocyte-derived macrophages with or without glucocorticoid treatment 13.49
Primary Human B-cell Temporal Response to CD40L Stimulation 13.41
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 13.36
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 13.34
RNA-Seq study of Cell lines rendered resistant to idelalisib and ibrutinib 13.3
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 13.17
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 12.98
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 12.98
Grainyhead-like 2 (GRHL2) and epigenetic remodeling in the intermediate states of epithelial-mesenchymal transition 12.92
Grainyhead-like 2 (GRHL2) and epigenetic remodeling in the intermediate states of epithelial-mesenchymal transition [RNA-seq] 12.92
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 12.88
Splicing and epigenetic factors jointly regulate epidermal differentiation 12.85
RNA-seq of MDA-MB-231 cells with TET1 knockout 12.43
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 12.41
JAK dependent survival of ALK- ALCL 12.28
Lipid degradation promotes prostate cancer cell survival 12.22
A novel target of EZH1/2 for treatment of mantle cell lymphoma 12.17
Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis 12.13
Androgen receptor programming in human tissue implicates HOXB13 in prostate pathogenesis [RNA-Seq] 11.81
Androgen receptor programming in human tissue implicates HOXB13 in prostate pathogenesis 11.81
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 11.71
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 11.67
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 11.6
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 11.55
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 11.47
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 11.32
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 11.32
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 11.3
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 11.25
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 10.92
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 10.71
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 10.66
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 10.66
Generation of KRAS signatures using immortalized isogenic lung cells. 10.63
Human lymph nodes maintain a unique subset of resident memory T cells with high functional potential important for protective immunity and immunotherapies 10.41
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 10.35
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 10.33
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 10.31
Transcriptome analysis of U87 cells upon LINC00152 knockdown 10.19
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 10.14
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 10.1
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 10.1
Ro60-knockout cells 10.01
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 9.96
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 9.92
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 9.87
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) reprograms melanoma microenvironment to promote antitumor T cell responses 9.87
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 9.86
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 9.84
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 9.84
GATA3-mediated chromatin reprogramming in breast cancer cells 9.79
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 9.78
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 9.78
CSL RNA-Seq on HKC and SCC cell lines 9.76
CSL 9.76
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 9.76
Human interleukin-4 treated regulatory macrophages promote epithelial wound healing and reduce colitis in an mouse model 9.57
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 9.53
The role of the Calcium-Sensing receptor in colorectal cancer 9.52
Transcriptome of activated human and mouse MAIT cells 9.47
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 9.38
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 9.36
Human neutrophil genome during PMA- and E. coli encounter-induced activation 9.36
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 9.36
Transcriptomes of oxLDL exposed trained monocytes 9.27
oxLDL exposed trained monocytes 9.27
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 9.18
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 9.18
AKAP8 inhibits tumor metastasis by antagonizing EMT-associated RNA alternative splicing 9.14
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 9.12
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 9.09
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 9.03
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 9.02
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 9.02
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 8.95
circNFIB suppresses lymphatic metastasis of pancreatic cancer 8.89
RNA seq_PDX2_SHP099 8.85
Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling 8.74
Proliferation-correlated expression 8.7
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 8.66
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 8.65
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 8.58
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 8.55
Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor 8.52
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 8.45
circRNA profile in hypopharyngeal cancer 8.2
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 8.18
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_TK] 8.14
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 8.11
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 8.08
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 8.07
A Unique Epigenomic Landscape Defines Human Erythropoiesis 8.07
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 8.0
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 7.97
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 7.93
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 7.91
Gene expression activation in CLL mediated by MSCs contact 7.78
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 7.77
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 7.72
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 7.69
Differential gene expression profiles in imatinib-resistant cell lines 7.69
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 7.67
Short and Long RNA sequencing of human mature erythrocytes 7.67
Control of prostate tumour growth by the long non-coding RNA GHSROS (LNCaP) 7.64
BACH2 in human plasma cell fate decision 7.59
The role of FAM46C in myeloma cells 7.58
The role of FAM46C in myeloma cells [sequencing] 7.58
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 7.51
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 7.49
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 7.47
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 7.42
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 7.41
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 7.39
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 7.25
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 7.23
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 7.2
Downregulation of LATS kinases alters p53 to promote cell migration 7.16
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 7.11
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 7.11
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 7.11
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 6.99
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 6.97
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells 6.97
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2) 6.97
Landscape and variation of RNA secondary structure across the human transcriptome 6.93
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 6.88
Gene expression in PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition. 6.88
Bone marrow derived human B cells [normal proB] 6.81
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 6.74
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 6.71
Transcriptomic analyssis following EHMT1/2 inhibition 6.7
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 6.7
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 6.68
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 6.61
Fusion discovery in breast cancer cell line 6.61
Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease 6.59
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 6.59
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 6.58
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 6.56
CircRNAome diversity in human mature B-cells, T-cells and monocytes 6.5
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 6.46
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 6.41
RNA-sequencing of bulk CD19+ Thymic B cells from young (3 month - 4 year) and old (42 - 61 years) humans 6.39
RNA-sequencing of bulk CD19+ Thymic B cells from mice and humans 6.39
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 6.36
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 6.36
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 6.36
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 6.36
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 6.32
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 6.31
Identification of renal resident macrophages across species [C1] 6.3
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 6.23
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 6.19
RNA-seq of cells with TET1 knockout 6.17
Patient-derived organoids (PDOs) model treatment response of metastatic gastrointestinal cancers. 6.12
Leucegene: AML sequencing (part 6) 6.07
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 6.04
Non-inflammatory tumor microenvironment of Diffuse Intrinsic Pontine Glioma (DIPG) 6.0
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 5.94
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 5.94
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 5.88
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 5.79
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 5.75
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. 5.7
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 5.64
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 5.64
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 5.63
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 5.61
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 5.61
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 5.6
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 5.56
Gene expression profile in breast cancer cells 5.56
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 5.53
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 5.53
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 5.5
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  5.48
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 5.41
Transcriptomes of human monocytes after ex vivo exposure to uric acid 5.4
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 5.36
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 5.32
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 5.32
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 5.31
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 5.31
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 5.28
RNA sequencing of human pancreatic cancer cell lines 5.16
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 5.1
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 5.07
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 4.97
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 4.96
RNA-sequencing of human tendon after injury 4.96
Targeted enhancer activation by a subunit of the integrator complex 4.95
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 4.94
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 4.82
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 4.82
Expression and functions of long noncoding RNAs during human T helper cell differentiation 4.75
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 4.74
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 4.67
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation 4.6
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 4.44
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 4.44
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 4.39
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 4.13
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 4.07
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 4.06
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 4.06
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 4.06
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 4.04
FOXP3 protects conventional human T cells from premature restimulation-induced cell death 4.02
RNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls 3.99
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 3.99
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 3.91
UBC9 knockdown in bladder cancer T24 cell lines 3.89
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 3.83
Transcriptome profiling of CXCR2+ neuroendocrine (NE) tumor cells purified from patients' fresh prostate adenocarcinoma 3.83
The effect of Abl kinases on non-small cell carcinoma global transcriptome 3.75
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 3.73
Transcriptomic responses to Ivacaftor and prediction of Ivacaftor clinical responsiveness 3.73
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 3.69
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 3.69
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 3.68
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 3.48
Transcriptome analysis revealed impaired cAMP responsiveness in PHF21A-deficient human cells 3.44
A practical evaluation of alignment algorithms for RNA variant calling analysis 3.41
Regulation of hypoxia-inducible factor activity by ZMYND8 3.38
Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region 3.37
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 3.35
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 3.35
Molecular Biomarkers Screened by Next-generation RNA Sequencing for non-sentinel lymph node status predicting in breast cancer patients with metastatic sentinel lymph node 3.25
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 3.22
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 3.22
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 3.2
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 3.14
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 3.13
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 3.1
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 3.09
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 3.0
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 2.95
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 2.95
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 2.95
Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq] 2.94
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 2.93
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 2.93
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 2.92
Expression profiling of converted and control dermal BJ fibroblasts 2.91
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 2.91
Polycomb complexes associate with enhancers to promote oncogenic transcriptional programs in cancer 2.9
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 2.87
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 2.83
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 2.8
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 2.79
Transcriptomes in healthy and CHB fetal hearts 2.78
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 2.77
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 2.76
Transcriptome analysis of peripheral blood monocytes 2.75
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and converts them into tumorigenic cells 2.69
Expression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions. 2.68
Gene expression of thyroid cancer cell lines 2.64
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 2.61
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 2.5
Identification of a LIF-responsive replication-competent human β cell 2.49
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 2.48
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 2.48
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 2.4
Pluripotent stem cell models of Blau syndrome reveal an IFN-<gamma>-dependent inflammatory response in macrophages 2.38
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 2.38
Identification of renal resident macrophages across species 2.36
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 2.34
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 2.34
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 2.34
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 2.24
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 2.24
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 2.19
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 2.19
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 2.18
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 2.18
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 2.17
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 2.03
Reprogrammed myeloid cell transcriptomes in NSCLC 2.0
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 1.99
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 1.98
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 1.95
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 1.93
Tissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases 1.93
RNA-Seq and expression data from human adipose tissue 1.93
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 1.92
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 1.89
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 1.89
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 1.79
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 1.74
Macrophage Ad5f35 PhenoMap 1.74
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 1.7
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 1.63
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 1.63
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 1.63
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 1.58
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway 1.58
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.54
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 1.53
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 1.51
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in Chronic Lymphocytic Leukemia 1.49
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 1.49
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 1.48
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 1.48
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 1.48
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 1.45
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 1.44
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation 1.42
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 1.42
Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines. 1.42
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 1.41
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 1.4
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 1.38
Ribosome profiling upon inhibition of eIF4A 1.37
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 1.34
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 1.32
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 1.23
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 1.19
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 1.19
Anti-inflammatory effect of indoleacrylic acid (IA) 1.17
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 1.14
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 1.09
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 1.09
Clinker: visualizing fusion genes detected in RNA-seq data 1.04
MRTF activates TEAD-YAP target gene expression 1.02
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.94
The role of m6A/m-RNA methylation in stress response regulation 0.94
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 0.94
RNA-Seq of CD4+ T cells treated with AS1842856 or DMSO 0.91
Transcriptional changes during naturally-acquired ZIKA Virus infection render dendritic cells highly conducive to viral replication 0.83
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 0.83
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 0.78
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia [RNA-seq] 0.73
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.73
mRNA sequencing of oropharyngeal cancer cell lines 0.71
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 0.69
Generation and persistence of human tissue-resident memory T cells in lung transplantation 0.68
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 0.67
RNA-seq of primary patient AML samples 0.62
Human ovarian granulosa cell transcriptome 0.58
RNA-sequencing in immortalized human mammary epithelial cells 0.57
Alternative splicing regulated by QKI and RBFOX1 promotes the mesenchymal cell state in breast cancer 0.57
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.49
Transcriptomic analysis of human macrophages in 3D 0.46
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.46
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.44
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.42
Specific molecular signatures underlie response to decitabine in CMML 0.42
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 0.39
RNA editing in nascent RNA affects pre-mRNA splicing 0.38
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 0.37
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 0.35
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.35
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.35
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.32
Xeno-free and Chemically Defined Human System for Culturing Human Epidermal Keratinocytes 0.32
Transcriptional analysis of ZIKV-infected Ifnar-/- and Ifnar+/- placentas and IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 0.29
Analysis of transcriptional differences after IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 0.29
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 0.28
Antiviral and anti-inflammatory properties of novel anti-HIV candidate ABX464 promotes specifics RNA splicing while preserving cellular RNA integrity. 0.25
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 0.24
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 0.23
Gene expression analysis of breast cancer cell-lines 0.18
Gene expression and genome-wide location analysis of breast cancer cell-lines 0.18
Trascriptome of thyroid cancer-induced macrophages 0.16
Dnmt3a and Dnmt3b associate with enhancers to regulate human epidermal stem cell homeostasis 0.13
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 0.13
Persistence of stem cell metabolism in cancers as a failure of differentiation 0.12
Gene expression of collecting duct carcinoma of the kidney 0.09
MHC Transcriptomic landscape at haplotype-specific resolution 0.03
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 0.03
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 0.01


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