Gene Query: AKR1C1

Dataset Description Geneva Score
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 331.76
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 204.69
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 163.08
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 135.48
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 134.8
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 130.16
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 128.36
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 114.13
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 114.13
MCF10A H-Ras RNA-Seq 111.9
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 102.65
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 91.06
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 90.53
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 88.11
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 85.99
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 84.16
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 84.16
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 79.08
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 77.14
RNA expression following TMPRSS11B overexpression or depletion 76.63
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 73.66
METTL3 promotes translation in human cancer cells 71.82
Nrf2 regulated genes in A549 cells 71.6
Identification of Nrf2 regulated genes by RNA sequencing 71.6
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 70.76
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 69.08
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 68.96
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 68.96
Inhibition of TNBC metastasis by Gpx1 68.23
Gene expression analysis of immortalized human liver progenitor-like cells in culture 64.78
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 64.37
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 63.45
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 61.58
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 60.6
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 59.98
6mer seed toxicity in tumour suppressive microRNAs 58.89
TGF-β promotes genomic instability after loss of RUNX3 57.52
Identification and Initial Functional Characterization of SENCR, a Long Non-Coding RNA Enriched in Human Vascular Cells 55.42
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 55.02
TFAP2C signalling in human fibroblasts 54.84
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 53.21
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 53.17
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 52.79
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 51.89
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 49.44
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 48.85
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 48.85
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 48.7
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 48.7
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 48.57
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 48.54
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 47.47
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 47.12
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 47.12
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 46.02
Identifying the molecular mode of action of itraconazole in colorectal cancer 45.26
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 44.9
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 44.74
Gene expression in PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition. 44.72
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 44.72
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 44.52
RNA-seq of cells with TET1 knockout 44.28
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 43.82
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 43.09
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 43.09
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 42.57
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 42.29
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 42.29
Redifferentiation of expanded human islet β cells by inhibition of ARX 41.59
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 41.24
Derivation of ventrical and atrial cardiomyocytes and maturation using biowires 40.91
RNA sequencing of human mammary epithelial cells 40.89
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 40.86
RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines 40.21
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 39.98
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 39.58
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 38.47
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 38.24
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 37.68
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 37.13
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 37.13
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 36.26
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 36.07
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 35.19
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 34.99
mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast 34.36
Genomic analysis of human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast 34.36
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 34.03
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 33.89
NHLRC1 re-expression in cancer cells 33.47
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 33.22
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 32.63
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 32.63
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 32.2
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 31.57
Generation of trichogenic adipose-derived stem cells by expression of three factors 31.54
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 31.25
Mutational landscape of splicing genes and functional consequences across 33 cancer types 30.91
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 30.61
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 30.43
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 30.43
RNA-seq in HepG2 and IMR90 cells 30.33
Evolution of a transcriptional regulator from a transmembrane nucleoporin 30.33
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 30.07
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 29.79
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 29.61
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 29.42
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells 29.32
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 29.06
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 29.06
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 29.02
RNA seq analysis of human Fetal and adult derived Enterospheres 28.99
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 28.82
Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney 28.34
RNA-seq analyisis of PUM2 knockout cells 27.85
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 27.71
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 27.46
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 27.44
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 27.44
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 27.06
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 27.05
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 27.0
TCF7L1 knockdown in pancreatic cancer 26.75
Transcriptome profiling of 5 human adenocarcinoma cell lines 26.71
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 26.44
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 25.98
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 25.94
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 25.39
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 25.36
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 25.14
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq] 25.11
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia 25.11
RNA seq comparison between scrambled and shGRP78 cells 24.89
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 24.88
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 24.87
An integrative network biology analysis identifies miR-508-3p as the determinant and a prognosis biomarker of the mesenchymal subtype ovarian cancer 24.86
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 24.83
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 24.63
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  24.33
Tumor exosome integrins determine organotropic metastasis 24.17
AKAP8 inhibits tumor metastasis by antagonizing EMT-associated RNA alternative splicing 24.16
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 24.11
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 24.11
Gene expression patterns define the hepatocyte-like cells derived by different strategies 23.85
Gene expression patterns define the hepatocyte-like cells derived by different strategies [RNA-seq] 23.85
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 23.72
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 23.72
RNA Sequencing of three pairs of gastric cancer 23.44
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 23.31
IRF2 is a master regulator of human keratinocyte stem cell fate 23.31
ARID1A regulates condensin II distribution and chromosomal partition [RNA-seq] 23.24
ARID1A regulates condensin II distribution and chromosomal partition 23.24
Discovering the anti-cancer potential of non-oncology drugs by systematic PRISM profiling 23.09
Single-nucleotide-resolution mapping of HBV promoters using CAGE 23.07
RNA sequencing of human fibroblasts after SUPT4H1 siRNA treatment 22.9
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 22.86
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 22.75
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 22.68
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 22.67
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 22.6
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 22.56
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 22.47
RNA-seq of MCF10A cells and CAF 22.32
Comparing effects of perfusion and hydrostatic pressure on human chondrocytes using gene profiles 22.29
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 22.24
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 22.1
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 22.1
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 22.08
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 22.08
Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS 21.46
High-Throughput Kinetic Analysis of Fractional Killing 21.1
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 20.93
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 20.71
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 20.55
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 20.45
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 20.33
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 20.27
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 20.16
Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells 20.14
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 19.97
G-quadruplex structures mark human regulatory chromatin 19.9
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 19.85
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 19.85
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation 19.78
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA 19.71
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 19.67
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 19.62
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 19.6
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 19.58
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 19.57
Differential gene expression profiles in imatinib-resistant cell lines 19.54
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 19.42
RNA-seq of human fibroblasts after irradiation 19.28
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 18.93
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 18.9
Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis 18.73
Epigenomic landscape during organ formation in human early embryos 18.72
Expression patterns in chronic thromboembolic pulmonary hypertension 18.7
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 18.56
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 18.56
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 18.36
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 18.35
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 18.19
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 18.15
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 18.15
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 18.04
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 18.03
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 18.01
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 17.9
PGE2 mediated gene expression changes in human cervical stromal cells 17.88
Oncogenic MYC induces a dependency on the spliceosome in human cancer 17.8
Gene expression profiling of KSHV-infected periodontal ligament cells 17.79
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 17.75
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 17.67
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 17.67
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 17.65
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 17.56
RNA-Seq of Kaposi’s sarcoma reveal alterations in glucose and lipid metabolism 17.31
Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling 17.31
Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2 17.25
Rorc disruption in human FG pancreatic cancer cells 17.24
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 17.21
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 17.21
Primary human trophoblast from term placenta 17.13
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 17.07
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 16.98
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 16.98
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 16.97
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 16.97
Transcriptome analysis of virus infected tissues 16.9
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 16.85
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 16.78
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 16.75
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 16.69
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 16.61
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 16.32
Gene expression profile difference among renal location in a stone former 16.18
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 16.11
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 16.11
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours 15.93
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours [RNA-seq] 15.93
Morphological and molecular characterization of human dermal lymphatic collectors 15.91
RNA m5C Methylation in breast cancer using MeRIP-Seq 15.81
RNA-seq and Microarray in Transcriptome Profiling of Anterior Cruciate Ligament Tears: Implications for Prognostic Biomarkers Discovery 15.76
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 15.75
Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC 15.65
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 15.58
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 15.58
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 15.58
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 15.4
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 14.95
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 14.72
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 14.72
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 14.64
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 14.51
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 14.37
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 14.32
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 14.32
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 14.24
Spliceosomal disruption of the non-canonical BAF complex in cancer 14.22
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 13.98
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 13.93
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 13.91
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Humans 13.9
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 13.74
Dnmt3a and Dnmt3b associate with enhancers to regulate human epidermal stem cell homeostasis 13.42
Gene expression alterations of pancreatic intraepithlial neoplasia 13.1
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 13.04
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 12.95
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 12.95
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 12.94
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 12.89
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 12.88
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 12.88
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 12.88
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 12.88
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 12.85
Chromatin landscape of human visceral and subcutaneous adipocytes 12.81
Global analyses of the effect of different cellular contexts on microRNA targeting 12.62
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 12.62
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 12.59
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 12.55
RNA sequencing of mechanically strained NHEKs and control NHEKs 12.38
Postnatal lipids drive hepatocyte maturation 12.33
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 12.29
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 12.06
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation 12.01
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 11.88
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 11.88
Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoids culture 11.81
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole] 11.8
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 11.53
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 11.41
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 11.38
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 11.38
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 11.38
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 11.36
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 11.34
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 11.21
The effect of PPARG inhibition on human angiomyolipoma cells 11.21
The effect of Abl kinases on non-small cell carcinoma global transcriptome 11.05
The landscape of alternative splicing in aggressive prostate cancers 11.0
circRNA-sequencing 10.97
Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection 10.83
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 10.79
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 10.78
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  10.73
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 10.67
Molecular analysis of renal cell carcinoma with unclassfied histology 10.64
Molecular analysis of renal cell carcinoma with unclassfied histology [gene expression] 10.64
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 10.62
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 10.29
Modulation of ESRP2 and MBNL2 in normal kidney and clear cell renal cell carcinoma cell lines for analysis of stability programs 10.29
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 10.11
Next Generation Sequencing of human SMA and healthy control Motor Neurons 9.87
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 9.67
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 9.64
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 9.6
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 9.6
An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch Type Alopecia Areata, Totalis and Universalis 9.58
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 9.56
RNA-seq of overgrown interscapular adipose tissue with biallelic MFN2 mutations 9.49
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 9.39
Selective expression of long non-coding RNAs in a breast cancer cell progression model 9.38
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 9.2
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 9.2
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 9.19
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 9.17
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 9.17
Transcriptome of human white and brown adipose tissue biopsies 9.15
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 9.13
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 8.83
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 8.83
RNA-seq of IL-4 stimulated human keratinocytes 8.8
Short and long-term effects of CDK4/6 inhibition on early stage breast cancer 8.73
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 8.68
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance 8.68
Divergent expression and metabolic functions of human glucuronosyltransferases through alternative splicing 8.67
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 8.64
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 8.62
Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice 8.62
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 8.56
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 8.36
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 8.32
Random mono-allelic expression in MECP2-mutated cells 8.31
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 8.3
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 8.19
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4 8.1
Aortic Valve Tissue: Stenosis vs. Sclerosis 8.01
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 7.91
ML29755 RNA-seq data 7.87
Bulk RNA-sequencing of cell types isolated by FACS from normal human prostates 7.78
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 7.77
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 7.77
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 7.69
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 7.65
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 7.65
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 7.64
RNA-sequencing of milk cells extracted from pre-partum secretions and longitudinally from mature human milk across the first year of lactation 7.6
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 7.54
Potential signaling pathways and gene signatures associated with brain metastases in NSCLC patients 7.51
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 7.38
BASP1 modifies the Tamoxifen response 7.31
High-throughput sequencing of the human hepatic progenitor cell niche in PSC and HCV. 7.23
Differentially Expressed Genes for Atrial Fibrillation Identified using RNA Sequencing from Paired Human Left and Right Atrial Appendages. 7.17
Patient-derived organoids (PDOs) model treatment response of metastatic gastrointestinal cancers. 7.16
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 7.06
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 7.06
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 6.98
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 6.95
Gene expression profiling of patient's DCIS-IDC tandem lesions by RNA sequencing analysis 6.9
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 6.89
RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes 6.58
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues [Total RNA] 6.55
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 6.53
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 6.52
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 6.44
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 6.27
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 6.27
ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle 6.21
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 6.19
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 6.13
mRNA sequencing of oropharyngeal cancer cell lines 6.12
Large-scale profiling of intracellular signalling pathway activation reveals major distinctions between airway smooth muscle cells of asthmatics and non-asthmatics. 5.99
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 5.97
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 5.94
mRNA differential expression analysis in a human ex vivo model of chronic wounds 5.82
Comparative transcriptome analysis reveals that ECM-Receptor Interaction contributes to the venous metastases of hepatocellular carcinoma 5.81
The gene expression profiles of gallbladder cancer 5.72
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 5.65
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 5.63
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 5.55
Dissecting the single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancer [10x genomics] 5.28
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 5.24
Multiple sclerosis and EAE 5.23
Human optic chiasm from healthy controls and multiple sclerosis patients 5.23
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 5.21
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 5.11
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 5.1
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution 5.06
Single Cell RNA-sequencing of cell types isolated by FACS from normal human prostates 5.03
circRNA profile in hypopharyngeal cancer 4.99
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 4.97
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 4.97
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 4.87
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 4.86
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 4.84
Gene expression of thyroid cancer cell lines 4.77
Finding missing proteins from epigenetically manipulated human cells 4.7
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 4.64
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 4.62
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 4.56
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 4.48
A single-cell transcriptome atlas of the human pancreas 4.33
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 4.31
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 4.31
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 4.27
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 4.24
Landscapes of gene translation in hepatocellular carcinoma tumors revealed by ribosome profiling 4.23
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 4.14
CHD1 regulates cell fate determination by activation of differentiation-induced genes 4.09
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I 4.01
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 3.98
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 3.98
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 3.84
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 3.82
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 3.82
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 3.82
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 3.79
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 3.61
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 3.45
Organoids derived from directly reprogrammed human hepatocytes for modeling liver cancer initiation 3.39
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 3.32
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 3.27
Discovery and verification of liver cancer marker genes and variable scission based on second-generation sequencing data analysis 3.08
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 2.94
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 2.93
RNA seq_PDX2_SHP099 2.92
Integrated Profiling of mRNAs and microRNAs to Identify Potential Biomarkers for Oral Malignant Transformation [mRNA-Seq] 2.76
Integrated Profiling of mRNAs and microRNAs to Identify Potential Biomarkers for Oral Malignant Transformation 2.76
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 2.69
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 2.67
Modeling Familial Cancer with iPSC Approaches 2.63
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 2.61
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 2.52
Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein, IFITM3 2.5
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 2.47
Identification of the role of polydom in neurofibromas 2.38
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 2.37
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 2.32
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 2.32
RNA sequencing analysis of selumetinib-resistant CRC cells lines 2.15
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 2.1
Gene expression analysis of human liver progenitor-like cells in culture 2.06
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 2.03
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 1.99
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 1.89
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 1.89
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 1.82
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 1.78
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 1.74
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 1.74
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 1.73
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells II 1.61
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 1.42
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 1.42
Tissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases 1.34
RNA-Seq and expression data from human adipose tissue 1.34
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 1.27
Gene profiling of human adult and pediatric liver cancer cells 1.23
STX4 Over-Expression in Human islets 1.21
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 1.19
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 1.16
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 1.12
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 1.08
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 1.06
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 1.06
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 0.87
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 0.83
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 0.8
EGR1-controlled transcriptome of T HESCs 0.79
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 0.72
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 0.7
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 0.67
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 0.6
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 0.57
Transcriptome analyses of human pancreatic islets and pseudoislets 0.43
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.41
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.41
Human islets of varying quality: the good, the (not so) bad and the ugly 0.4
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 0.22
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 0.22
Anti-Inflammatory Effects of Budesonide in Human Fetal Lung 0.2
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 0.16
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 0.14
BMS-470539 on human synovial fibroblasts 0.1
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.05
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.05
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 0.04
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.01


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