Gene Query: AKT1

Dataset Description Geneva Score
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 50.13
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 50.13
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 35.45
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 32.51
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 28.74
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 28.14
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 27.63
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion 27.55
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 27.09
SNHG5 siRNA knock down in HCT116 cells 26.31
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 25.73
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 25.73
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 24.19
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 23.51
HNF1 regulates critical functions of the human epididymis epithelium. [RNA-Seq] 23.43
HNF1 regulates critical functions of the human epididymis epithelium. 23.43
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 23.41
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 23.06
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 23.06
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 22.52
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 21.26
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 20.74
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 20.73
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 20.73
RNA-seq of YB5 cells treated with Proscillaridin A 19.55
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 19.13
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 18.84
Intrahepatic MAIT cell gene expression revealed by RNA-seq 18.69
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 18.5
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 18.38
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 18.18
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 17.98
Stem and effector CD8 T-cells from human cancers 17.88
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 17.76
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 17.67
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 17.6
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 17.36
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 17.36
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 17.22
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 16.87
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 16.87
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling 16.81
DART-seq: an antibody-free method for global m6A detection 16.73
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 16.69
Mechanistic Model-Guided Study of Embryonic Morphogenesis 16.59
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 16.49
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy 16.14
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 16.02
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 16.02
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 15.98
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 15.98
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 15.86
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 15.73
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 15.65
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 15.65
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 15.61
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 15.57
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 15.45
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 14.95
MYC dependent mRNA translation shapes gene expression and cell biology 14.84
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 14.83
miR941 overexpression experiment 14.79
MYCi361 regulates MYC target genes 14.6
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 14.46
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis 14.44
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 13.98
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 13.87
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 13.37
Role of XRN2 ribonucleolytic activity in RNA metabolism 13.24
Nucleoporin-mediated regulation of cell identity genes 13.24
RNA sequencing of primary human platelets and in vitro cell lines 13.21
Grainyhead-like 2 (GRHL2) and epigenetic remodeling in the intermediate states of epithelial-mesenchymal transition [RNA-seq] 13.21
Grainyhead-like 2 (GRHL2) and epigenetic remodeling in the intermediate states of epithelial-mesenchymal transition 13.21
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 13.18
DIGIT regulates endoderm differentiation of human embryonic stem cells 13.11
Gene expression analysis of dengue-infected cells 12.94
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 12.84
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 12.79
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 12.77
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 12.77
Identification of Nrf2 regulated genes by RNA sequencing 12.76
Nrf2 regulated genes in A549 cells 12.76
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 12.7
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 12.67
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 12.67
RNA-sequencing in irradiated and normal A549 cells. 12.63
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 12.62
Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes 12.56
Exogenous rescue of KLHL9 in SF210 cell line 12.4
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 12.31
Human neutrophil genome during PMA- and E. coli encounter-induced activation 12.31
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 12.31
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 12.3
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 12.3
High-throughput sequencing of pluripotent cells 12.27
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 12.11
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 12.09
Global transcriptome analysis of HAP1 cells 12.05
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 12.0
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 11.99
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 11.76
Region-specific Innate Antiviral Responses of the Human Epididymis 11.69
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 11.52
Expression level comparison under dividing and quiescent states in human primary fibroblasts 11.47
Identification of Atrial Fibrillation associated genes and functional non-coding variants 11.41
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 11.36
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 11.36
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 11.34
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 11.31
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 11.29
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 11.15
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 11.09
Ribosomal footprinting of MDA-Parental and MDA-LM2 11.07
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 11.04
SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis 10.89
ChIP-seq and RNA-seq from human lymphoma cell lines 10.87
RNA-seq data from human lymphoma cell lines 10.87
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 10.73
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 10.73
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 10.62
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 10.61
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 10.6
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 10.55
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 10.49
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 10.49
Loss of CREBBP results in gene expression repression in lymphoma cells 10.38
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 10.38
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 10.3
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 10.3
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 10.29
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 10.23
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 10.21
Genome wide miR-191 target profile determined by RIP and gene expression profiling 10.21
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 10.21
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 10.16
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 10.15
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 10.1
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 10.0
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 10.0
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 9.94
Transcriptome profiling identified a 3-lncRNA regulatory network in transthyretin against glucose induced hRECs dysfunction 9.92
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 9.9
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 9.9
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 9.88
RNA sequencing analysis of human embryonic stem cells and axial progenitors 9.88
The regulartory role of ZCCHC24 in splicing machinery 9.87
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 9.86
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 9.86
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 9.81
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 9.76
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 9.76
Differentiation enhances Zika virus infection in neuronal brain cells 9.76
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 9.68
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 9.61
mRNA expression profile of Lymphocytes by high-throuput sequencing 9.61
Studying the selectivity of a small molecule Synucleozid on transcriptome 9.59
LINC00520 is Induced by Src, STAT3, and PI3K and Plays a Functional Role in Breast Cancer 9.59
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 9.58
Control of prostate tumour growth by the long non-coding RNA GHSROS 9.43
HNF1A deficiency impairs β-cell fate, granule maturation and function 9.37
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 9.31
RNA m5C Methylation in breast cancer using MeRIP-Seq 9.26
The comparison of high-throughput single-cell RNA-seq methods 9.24
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 9.14
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 9.05
Ribosomal footprinting of CN34-Parental and CN34-LM1a 9.03
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 9.02
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 8.99
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 8.95
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 8.94
RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways 8.94
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 8.84
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 8.8
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 8.79
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 8.76
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 8.76
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 8.76
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 8.75
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 8.7
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 8.66
Sensing self and nonself circular RNAs 8.61
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 8.55
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 8.53
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 8.52
RNA-seq analyisis of PUM2 knockout cells 8.52
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 8.48
RNA transcriptome analysis during HSV-1 infection 8.45
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 8.42
hTERT promotes cell adhesion and migration independent of telomerase activity 8.4
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 8.39
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 8.32
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 8.3
3’ Uridylation Expands miRNA Target Repertoire 8.29
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 8.26
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 8.26
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 8.24
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 8.17
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 8.16
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 8.15
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 8.15
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 8.15
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 8.09
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 8.08
Gene expression in PANC1 cells treated with Rakicidin 8.06
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 8.06
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 8.03
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 8.0
Characterization of parental and rociletinib-resistant derived H1975 cell lines 7.98
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 7.97
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 7.96
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 7.95
Transcriptomic analysis of LSD1 7.93
RNA-Seq analysis of breast cancer cells after shikonin treatment 7.93
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. 7.91
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 7.89
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 7.87
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 7.82
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 7.78
U1 snRNP telescripting regulates size-function stratified human genome 7.77
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 7.72
The transcriptome and chromatin accessbility landscape of mammalian germline 7.68
Developmental stage specific chromosome architecture in human erythroid cells 7.66
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 7.66
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 7.62
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 7.59
DHX36 is the missing link to understand RNA G-quadruplex structures, mRNA stability, and translation [RNA-seq] 7.54
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 7.52
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 7.52
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 7.5
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 7.5
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 7.49
Differential gene expressions in the heart of hypertrophic cardiomyopathy patients 7.45
CD73 knockdown effect in pancreatic cancer cell lines 7.42
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 7.39
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 7.39
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 7.32
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 7.27
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 7.25
Genome-wide analysis of Dengue virus 2 infected cells 7.24
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 7.24
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 7.2
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 7.2
RNA-seq analysis of differentiating human erythroblasts 7.19
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 7.13
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 7.13
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 7.13
RNA-seq of Single-Cell Genotyping of Transcriptomes 7.1
Single-Cell Genotyping of Transcriptomes 7.1
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 7.05
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 7.05
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 7.05
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 7.04
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 7.0
TT-Seq captures the human transient transcriptome 6.95
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 6.94
IMP3 regulated gene expression in breast cancer cells 6.89
Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a Colorectal Cancer Patient-derived Tumor Explant Model 6.89
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 6.89
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 6.83
miR-93 Targets in Human Endothelial Cells 6.83
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 6.82
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 6.75
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 6.71
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 6.7
Exploring the RNA landscape of endothelial exosomes 6.63
METTL3 and WTAP 6.6
Systematic discovery of endogenous human ribonucleoprotein complexes 6.57
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 6.55
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 6.49
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 6.49
Integrative classification of human coding and non-coding genes based on RNA metabolism profiles 6.49
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 6.45
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 6.42
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 6.39
RNA-sequencing of formalin fixed human primary melanoma tissue 6.37
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 6.32
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 6.23
RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma 6.21
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 6.21
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 6.21
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes 6.2
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 6.19
RNA-seq analysis of RALD iPSCs after in vitro differentiation 6.19
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 6.19
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 6.16
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 6.16
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 6.16
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 6.11
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 6.1
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 6.1
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 6.06
Comparing effects of perfusion and hydrostatic pressure on human chondrocytes using gene profiles 6.03
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 6.02
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 6.01
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 5.99
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 5.96
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 5.9
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 5.83
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 5.83
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 5.82
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 5.74
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 5.68
Molecular Mechanisms of Endothelial Hyperpermeability 5.66
Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma [RNA-Seq] 5.65
Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma 5.65
Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response 5.62
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 5.6
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 5.53
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 5.53
Human lymph nodes maintain a unique subset of resident memory T cells with high functional potential important for protective immunity and immunotherapies 5.51
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 5.49
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 5.46
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 5.41
Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation 5.36
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 5.3
Illumina sequencing of vaginal epithelial cells from women using depot medroxyprogesterone acetate or non-hormonal contraception 5.2
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 5.17
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 5.17
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 5.09
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 4.99
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 4.99
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 4.99
Human cells contain natural double-stranded RNAs with potential regulatory capacity 4.98
RNA-seq of cultured human kidney peritubular microvascular endothelial cells following exposure to cyclosporine A 4.96
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 4.95
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 4.95
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 4.93
Transcriptome analysis of peripheral blood monocytes 4.91
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 4.85
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 4.72
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 4.66
Isolation and Functional Interrogation of Adult Human Prostate Epithelial Stem Cells at Single Cell Resolution 4.53
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells 4.52
TOP2B disturbed the quality of human oocytes with advanced maternal age 4.51
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 4.47
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 4.46
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 4.43
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 4.43
Epigenetic reprogramming of melanoma cells by vitamin C treatment 4.43
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 4.4
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells 4.36
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 4.3
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 4.29
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 4.27
DAOY-Notch1/Notch2 knockout: transcriptome comparison 4.26
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 4.23
HEK293 TFAM Knockout Expression Study 4.2
Subclonal cooperation drives metastasis through modulating local and systemic immune microenvironments 4.18
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 4.1
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 4.08
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 4.03
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 4.01
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 3.98
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 3.98
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 3.95
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 3.89
Differential responses of human fetal brain neural stem cells to Zika virus infection 3.85
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 3.85
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 3.85
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 3.79
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 3.77
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 3.77
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 3.76
The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactions 3.74
Transcription elongation regulates genome 3D structure 3.74
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 3.73
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 3.68
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 3.66
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 3.64
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 3.63
Downregulation of DDX5/DDX17 and REST 3.49
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 3.48
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 3.48
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 3.43
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 3.43
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 3.42
Gene expression profiles of rescue with wild type or SUMO double mutant TRIM24 3.42
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 3.42
Tpl-2 small molecule project 3.41
Tpl-2 and MEK small molecule inhibitors 3.41
Compare of gene expression between p16INK4A positive and negative regions of colon cancer from five patients 3.41
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 3.39
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 3.39
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 3.39
Illumina Total RNA-seq in HeLa 3.36
Next Generation Sequencing identifying the dosage compensation state in human endometrial carcinoma and adjacent tissues 3.33
RNA-seq of RKO cells with cTAZ KO or putback 3.31
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 3.21
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 3.18
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 3.16
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 3.16
Profiling in vivo Bone Lesion (IVBL) and Orthotopic tumors by Next Generation Sequencing 3.13
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 3.13
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 3.13
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 3.07
Trascriptome of thyroid cancer-induced macrophages 3.03
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 3.0
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 2.99
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 2.95
Gene expression analysis of human hepatocellular cancers 2.94
SRSF1 role in cellular gene expression and splicing 2.93
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 2.9
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 2.87
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 2.85
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 2.82
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 2.79
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 2.79
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.75
Recovery and analysis of nascent RNA 2.67
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 2.67
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 2.57
Transcriptomic Analysis Of circRNAs/miRNAs/mRNAs upon Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection 2.56
Determining mRNA half-lives on a transcriptome-wide scale 2.54
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells 2.52
Loss of EGFR-DDEF1 signaling in metastatic and unresectable hepatoblastoma 2.52
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 2.4
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 2.33
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 2.33
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 2.28
Primate-specific gene TMEM14B promotes cortical expansion and folding 2.21
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 2.06
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 2.04
Epigenomic conservation of transposable element silencing [RNA-seq] 2.01
Epigenomic conservation of transposable element silencing 2.01
RNA-seq of CD33 KO and control HSPCs 2.01
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 1.96
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 1.94
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 1.89
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 1.85
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 1.69
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 1.68
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001 1.68
HEK293 Heat-shock experiment 1.67
Ribosome profiling upon inhibition of eIF4A 1.61
In search for materials able to be colonized by a normal endothelium: сharacterization and NGS gene expression profiling of human primary endotheliocytes cultivated on electrospun 3D matrices 1.59
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 1.53
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 1.51
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 1.41
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 1.39
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 1.37
Toxoplasma gondii infection of human retinal pigment epithelial cells 1.37
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.36
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 1.29
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 1.29
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 1.25
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 1.23
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 1.23
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 1.22
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 1.2
Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection 1.18
Deep RNA sequencing of the human placental transcriptome 1.16
A practical evaluation of alignment algorithms for RNA variant calling analysis 1.15
hESC neural differentiation 1.15
RNA-seq analysis of gene expression patterns during hESC neural differentiation 1.15
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 1.07
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 1.07
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 1.05
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 1.0
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 1.0
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 0.98
Global transcriptome analysis of WT versus HEB-/- hESCs 0.85
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.85
Metabolism as an early predictor of DPSCs aging 0.81
Efficient derivation of microglia-like cells from human pluripotent stem cells 0.76
Transcriptional changes in lymphoma cells induced by LSD1 depletion 0.76
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 0.76
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 0.74
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 0.74
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 0.73
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 0.73
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.7
K562 polyA RNA-Seq 0.7
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 0.68
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 0.67
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 0.67
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 0.66
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 0.65
Transcriptomes in healthy and CHB fetal hearts 0.53
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 0.43
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.36
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.36
RNA expression profiles comparing primary and omental ovarian carcinoma samples 0.32
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 0.28
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 0.24
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 0.24
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 0.18
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.18
Effects of transcription factor CEBPA knockdown on vitamin D target gene regulation in THP-1 cells 0.15
The pioneer factor CEBPA modulates vitamin D signaling 0.15
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.13
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) in proliferation, quiescence, senescence and transformed states. 0.1
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.09
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 0.06
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 0.06
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.05
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.05
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 0.03
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 0.02
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 0.02
Dermal endothelial cells of type 2 diabetic patients 0.01


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