Gene Query: APH1B

Dataset Description Geneva Score
Transcriptome analysis of U87 cells upon LINC00152 knockdown 21.02
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche 20.64
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 20.55
Gene expression changes in human melanoma cell lines compared to primary melanocytes 19.46
The Human Testis Cell Atlas via Single-cell RNA-seq 19.23
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics. 17.43
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 16.74
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 15.37
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 15.37
Gene expression profiling of leukemia cells following asparagine depletion 13.23
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 13.17
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 13.17
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 11.94
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 11.83
Global transcriptome analysis of HAP1 cells 11.51
Paxillin regulates genomic networks in prostate cancer [LNCaP] 11.04
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 10.46
Nrf2 regulated genes in A549 cells 10.19
Identification of Nrf2 regulated genes by RNA sequencing 10.19
The landscape of alternative splicing in aggressive prostate cancers 9.27
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with Eralpha 9.24
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 8.31
LNCaP treated with iBET 8.18
RNA sequencing of BT142 and TS603 cell lines 8.17
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 8.17
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 7.94
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 7.63
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 7.63
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 7.58
HNRNPL and its RNA Targets in Prostate Cancer 7.58
The conserved transcriptional landscapes in human spermatogenesis 7.48
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 7.32
AKAP8 inhibits tumor metastasis by antagonizing EMT-associated RNA alternative splicing 7.2
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 7.19
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 7.17
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 7.01
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 7.01
RNA-seq of shEZH2 cells 6.99
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 6.92
Region-specific Innate Antiviral Responses of the Human Epididymis 6.78
Cleavage Factor Im as a key regulator of 3’ UTR length 6.63
RNA-Seq in PWS iPSC-derived neurons 6.55
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression [RNA-seq] 6.52
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression 6.52
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 6.44
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 6.44
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 6.34
A role for ZNF598 in post-transcriptional gene regulation 6.34
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 6.13
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 6.03
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 6.02
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 6.02
High-Throughput Kinetic Analysis of Fractional Killing 5.91
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 5.88
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 5.83
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 5.83
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 5.79
The DNA methylation landscape of human melanoma 5.77
The DNA methylation landscape of human melanoma [RNA-Seq] 5.77
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 5.74
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 5.74
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 5.69
Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms 5.65
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 5.51
FOXP2's impact on the primate transcriptome 5.51
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 5.39
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 5.39
Role for citron kinase in prostate cancer growth 5.39
Novel Non-catalytic Substrate-selective p38α-specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-inflammatory Activity 5.36
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 5.27
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 5.16
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 5.13
HNRNPM-regulated splicing dependencies in prostate cancer 5.13
A sister of NANOG regulates genes expressed in pre-implantation human development 5.12
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization [RNA-Seq] 5.04
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization 5.04
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 4.94
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 4.91
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 4.9
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 4.9
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 4.89
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 4.88
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 4.8
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 4.73
AR-independent prostate cancer is sustained through FGF signaling 4.68
TFAP2C signalling in human fibroblasts 4.64
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 4.6
Transcriptome-wide identification of CELF2 functional targets in T cells 4.54
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 4.42
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 4.4
Expression profiling of etoposide-induced senescent cells 4.36
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 4.35
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 4.31
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 4.3
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 4.26
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 4.21
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 4.15
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 4.15
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 4.09
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 4.06
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 4.05
Genome wide expression change in LCC2 and MCF-7 cells 3.97
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 3.96
STX4 Over-Expression in Human islets 3.85
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 3.84
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 3.82
BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage (Gene expression profiling in several tetrapod species, bulk tissue RNA-seq) 3.81
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 3.8
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 3.76
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 3.76
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 3.74
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 3.72
TGF-β promotes genomic instability after loss of RUNX3 3.7
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 3.7
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 3.69
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 3.69
EGR1-controlled transcriptome of T HESCs 3.69
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 3.68
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 3.66
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 3.63
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 3.63
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 3.59
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 3.56
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 3.55
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 3.52
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 3.52
RNA-seq data from human lymphoma cell lines 3.45
ChIP-seq and RNA-seq from human lymphoma cell lines 3.45
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 3.45
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 3.44
Gene expression profile difference among renal location in a stone former 3.43
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 3.42
Depicting early human development and germ cell origin with porcine embryos 3.42
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 3.4
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 3.4
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 3.39
CD74 role in transcription regulation 3.39
CD74 role in transcription regulation [RNA-seq] 3.39
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 3.37
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 3.37
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 3.36
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 3.36
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 3.33
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 3.32
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 3.32
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 3.31
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 3.31
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 3.31
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 3.31
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 3.28
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 3.25
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 3.23
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 3.22
Comparing gene expression in iPSC derived RPE from control and AMD donors 3.15
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 3.14
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 3.13
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 3.12
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 3.11
Random mono-allelic expression in MECP2-mutated cells 3.11
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 3.09
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 3.05
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 3.02
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 3.01
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 2.99
RNA-seq analyses of human prostate cancer cells 2.99
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 2.93
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 2.93
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 2.91
Functional role of CPPED1 in trophoblasts. 2.9
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 2.9
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 2.87
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 2.87
Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2 2.86
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 2.86
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 2.84
Neonatal and adult human testis defined at the single-cell level 2.83
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 2.8
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 2.8
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 2.79
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 2.78
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma [RNA-Seq; normal samples] 2.75
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 2.74
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis 2.74
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 2.73
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 2.73
RNA sequencing to compare gene expession in control and PF228-treated hepatic stellate cells 2.72
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 2.72
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 2.71
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 2.71
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 2.67
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 2.66
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 2.65
Generation and persistence of human tissue-resident memory T cells in lung transplantation 2.65
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 2.64
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 2.64
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 2.61
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 2.61
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 2.6
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 2.54
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 2.54
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 2.54
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 2.51
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 2.51
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 2.51
Efficient derivation of microglia-like cells from human pluripotent stem cells 2.5
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 2.48
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 2.48
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 2.47
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 2.46
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 2.46
Transcriptome analysis of VCaP xenografts resistant to dual therapy with abiraterone and enzalutamide 2.44
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 2.43
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 2.41
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 2.41
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 2.4
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 2.39
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 2.39
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 2.38
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 2.37
6mer seed toxicity in tumour suppressive microRNAs 2.35
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 2.33
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 2.33
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 2.33
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 2.33
Genome-wide functional assessment of enhancer activities in the human genome 2.33
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in Chronic Lymphocytic Leukemia 2.32
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 2.32
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 2.31
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 2.31
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 2.31
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 2.29
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 2.29
IL-33 activates tumor stroma to promote intestinal polyposis 2.28
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 2.28
Proliferation-correlated expression 2.27
Conservative alteration of chromosomal expression pattern across human solid tumor types 2.26
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 2.26
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 2.26
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 2.26
A Unique Epigenomic Landscape Defines Human Erythropoiesis 2.26
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 2.26
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression 2.25
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [RNA-Seq] 2.25
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 2.23
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 2.22
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 2.2
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 2.19
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 2.19
Universal alternative splicing of noncoding exons 2.18
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 2.18
Discovering human diabetes-risk gene function with genetics and physiological assays 2.14
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 2.14
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 2.12
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 2.11
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 2.11
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 2.1
Pharmacologic inhibition of STAT5 in AML 2.07
MeRIP-seq for heat shock in B-cell lymphoma cells 2.07
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 2.06
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 2.06
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 2.05
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 2.05
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 2.05
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 2.04
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 2.04
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 2.04
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 2.03
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 2.01
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 2.01
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 2.01
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 2.0
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 2.0
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 1.98
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 1.98
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 1.92
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 1.91
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 1.91
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 1.91
Forkhead domain mutations in FOXA1 drive prostate cancer cell progression 1.9
RNA-seq in LNCaP cell line overexpressing WT or mutant FOXA1 1.9
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 1.89
Transciptomic profiling of human fetal lung samples 1.87
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 1.87
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 1.87
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 1.86
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 1.85
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 1.85
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 1.85
MCF-7 as a model for functional analysis of breast cancer risk variants 1.81
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 1.8
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 1.8
CDK4/6 inhibitor resistance in prostate cancer 1.79
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines 1.78
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines [RNA-seq] 1.78
RNA editing in nascent RNA affects pre-mRNA splicing 1.78
RNA-sequencing analysis of human fibrolamellar hepatocellular carcinoma and 4 maturational stages of the human hepatobiliary system 1.77
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 1.75
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 1.75
A map of gene expression in neutrophil-like cell lines 1.74
Effect of PRDM11 depletion in U2932 cells 1.74
Trascriptome of thyroid cancer-induced macrophages 1.71
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 1.71
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 1.71
DIGIT regulates endoderm differentiation of human embryonic stem cells 1.69
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 1.69
Human HAP1 cells before and after nutrient deprivation 1.69
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 1.69
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 1.69
Total RNA-Seq data from leukemic patients with complex structural variants 1.68
Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation 1.67
mRNA expression profile of Lymphocytes 1.66
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 1.66
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 1.65
RNA-seq of IL-4 stimulated human keratinocytes 1.64
RNA-seq profiling identifies Androgen Receptor-regulated genes in prostate cancer cells 1.61
Androgen Receptor-regulated genes in prostate cancer cells 1.61
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 1.6
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 1.58
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 1.58
Transcriptional changes in lymphoma cells induced by LSD1 depletion 1.58
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 1.58
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 1.58
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 1.56
RNA-seq analysis upon ARID1B overexpression 1.54
LIN28A modulates splicing and gene expression programs in breast cancer cells 1.54
LIN28A modulates splicing and gene expression programs in breast cancer cells [RNA-Seq] 1.54
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 1.52
Primate-specific gene TMEM14B promotes cortical expansion and folding 1.48
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 1.48
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 1.47
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 1.46
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 1.46
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 1.44
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 1.43
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 1.43
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 1.42
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 1.42
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 1.4
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 1.4
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 1.39
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 1.39
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.38
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 1.37
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 1.36
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 1.35
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 1.35
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 1.34
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 1.33
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.31
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 1.3
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 1.28
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 1.27
Transcriptome of Stabilin-1 siRNA transfected human monocytes 1.27
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 1.27
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 1.27
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas 1.25
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 1.23
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 1.23
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 1.23
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 1.22
Transcriptome profiling of 5 human adenocarcinoma cell lines 1.19
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction 1.18
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 1.17
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 1.16
Identification of a LIF-responsive replication-competent human β cell 1.15
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 1.14
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 1.13
Global transcriptome analysis of WT versus HEB-/- hESCs 1.13
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 1.13
Next Generation Sequencing of human SMA and healthy control Motor Neurons 1.1
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 1.09
The pause-initiation limit restricts transcription activation in human cells 1.08
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.07
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 1.07
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 1.06
Transcription control by the ENL YEATS domain in acute leukemia 1.06
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 1.05
Comparative Analysis of the Transcriptome of Latent Autoimmune Diabetes (LADA) Patients from Eastern China 1.05
Genome-wide expression analysis of young, senescent and p38MAPK-inhibitited senescent human fibroblasts. 1.03
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 1.03
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 1.01
Identification of long noncoding RNAs in T-ALL cell lines 1.01
Expression profiling of converted and control dermal BJ fibroblasts 0.98
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 0.98
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 0.95
The transcriptome and chromatin accessbility landscape of mammalian germline 0.95
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 0.93
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 0.93
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia 0.93
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 0.93
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 0.93
Identification of global XBP1s target gene expression in human prostate cancer cells 0.91
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 0.89
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 0.89
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 0.88
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 0.87
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 0.87
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 0.87
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 0.86
Role of cervicovaginal microbiota in genital inflammation 0.83
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 0.82
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 0.82
Genome-wide RNA-sequencing (RNA-seq) of benign and malignant prostate cell lines without and with androgen (R1881) stimulation. 0.81
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 0.8
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug 0.8
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [human] 0.8
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 0.79
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 0.79
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 0.79
Transcriptional effect of ETV1 knockdown in melanoma cells 0.78
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA 0.78
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 0.74
TAF1 is critical for AE driven leukemogenesis 0.74
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 0.73
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 0.73
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 0.73
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 0.72
Primary Human B-cell Temporal Response to CD40L Stimulation 0.72
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.71
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 0.7
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 0.7
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 0.69
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 0.68
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors 0.67
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 0.63
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.61
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 0.61
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 0.61
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 0.6
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.59
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 0.58
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 0.57
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 0.57
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 0.53
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 0.53
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 0.53
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 0.52
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 0.52
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 0.5
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 0.5
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.48
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.47
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 0.45
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 0.45
Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC 0.44
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 0.43
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.42
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.39
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 0.37
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 0.35
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 0.34
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 0.34
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 0.33
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.32
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 0.31
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 0.31
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 0.29
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 0.29
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 0.28
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.27
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 0.27
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.27
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) 0.26
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) [RNA-seq] 0.26
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 0.26
Single Cell RNASeq profiling of stromal vascular fraction from Subcutaneous and visceral adipose tissue 0.26
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 0.25
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 0.24
Analysis of human, chimpanzee, macaque and mouse tissue transcriptomes using Next Generation Sequencing 0.24
6mer seed toxicity in viral microRNAs 0.23
Ribosomal protein RPL26 is the principal target of UFMylation 0.21
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.21
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.21
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 0.21
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.21
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.21
FOXP1 orchestration of ASD-relevant signaling pathways. 0.19
Transcriptomic analysis of human macrophages in 3D 0.19
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.19
Preclinical model of obesity and ER-positive breast cancer 0.18
Neutrophils RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 0.17
hNSCs siRNA NOVA2 0.17
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 0.17
Human islets of varying quality: the good, the (not so) bad and the ugly 0.16
Epigenomic conservation of transposable element silencing 0.16
Epigenomic conservation of transposable element silencing [RNA-seq] 0.16
Intrinsic histone acetyltransferase activity of BRD4 is responsible for nucleosome eviction and transcriptional activation 0.14
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells 0.13
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 0.12
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I 0.12
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 0.12
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 0.1
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.06
Oncogenic roles of ARID5B in T-ALL 0.06
Leucegene: AML sequencing (part 6) 0.06
Microglia innatly develop within cerebral organoids 0.05
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 0.04
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 0.04
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 0.03
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 0.03


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