Gene Query: BCKDHA

Dataset Description Geneva Score
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 25.4
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 23.17
Gene expression analysis of immortalized human liver progenitor-like cells in culture 19.52
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 19.49
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 19.49
Dtx3L and Androgen Signaling in Prostate Cancer 18.11
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 17.28
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 16.95
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 16.95
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 16.47
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq] 16.37
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 15.14
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 14.43
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 14.3
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 14.3
Subclonal cooperation drives metastasis through modulating local and systemic immune microenvironments 14.22
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 14.18
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 14.16
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 13.68
RNA-seq analysis of uveal melanoma cells treated with FR900359 13.55
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 13.46
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 13.39
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 13.33
Genome wide expression change by RNF168 knocking down in MCF-7 cells 13.25
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 13.18
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 13.07
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 13.05
Large-scale profiling of intracellular signalling pathway activation reveals major distinctions between airway smooth muscle cells of asthmatics and non-asthmatics. 12.82
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 12.11
Gene expression analysis in response to hypoxic pathway inhibition 11.93
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 11.87
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 11.87
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 11.87
RNA-seq of tumor cells following angiopellosis extravasation 11.86
Mutational landscape of splicing genes and functional consequences across 33 cancer types 11.81
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 11.78
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 11.47
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 11.38
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 11.02
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 11.02
Evaluating pre-clinical models for studying NASH driven HCC. 11.01
A549 cell transcriptome responses to infection with H7N9 influenza virus 10.95
Pharmacologic inhibition of STAT5 in AML 10.82
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 10.5
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 10.49
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 10.38
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 9.99
H1609088 Human RNA-Sequencing 9.97
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 9.94
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 9.84
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 (RNA-Seq) 9.83
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 9.83
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 9.8
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 9.77
RNA-seq of naive and primed ES cells (NHSM) 9.46
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 9.35
Energy Metabolism during Anchorage-Independence 9.3
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 9.14
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 9.01
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 8.99
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 8.99
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 8.89
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 8.86
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 8.83
Transcriptome of human white and brown adipose tissue biopsies 8.8
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 8.58
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 8.53
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 8.52
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 8.41
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 8.34
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 8.24
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 8.24
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 8.24
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 8.12
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 8.1
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 7.83
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 7.83
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 7.83
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 7.79
Transcriptome analysis of SKI knock-out in HL60 cells 7.79
Ro60-knockout cells 7.77
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 7.61
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 7.52
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 7.51
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 7.45
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 7.42
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 7.27
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 7.27
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 7.27
RNA-seq analysis of BAP1-depleted uveal melanoma cells 7.17
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 7.11
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 7.09
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 7.03
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 6.91
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 6.9
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 6.9
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 6.81
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 6.68
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 6.56
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 6.55
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 6.49
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 6.38
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 6.36
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 6.36
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 6.25
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 6.21
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 6.18
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 6.17
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 6.17
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 6.08
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 6.08
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 6.08
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 6.06
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 6.02
RNA-seq in transgenic cells 6.01
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 6.01
Genome wide expression change in LCC2 and MCF-7 cells 6.0
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes 5.98
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 5.97
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 5.97
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 5.94
A Unique Epigenomic Landscape Defines Human Erythropoiesis 5.94
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 5.93
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 5.93
ARS2 is a general suppressor of pervasive transcription [RNAseq] 5.88
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 5.87
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 5.81
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 5.8
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 5.78
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 5.78
METTL3 promotes translation in human cancer cells 5.74
Small-molecule targeting of brachyury transcription factor addiction in chordoma 5.66
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 5.66
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 5.65
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 5.63
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 5.62
Oncogenic MYC induces a dependency on the spliceosome in human cancer 5.59
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 5.56
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 5.47
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 5.47
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 5.46
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 5.39
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 5.38
Functional Haploid Human Oocytes Generated from Polar Body Genomes 5.28
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 5.28
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 5.19
hTERT promotes cell adhesion and migration independent of telomerase activity 5.14
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 5.11
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 5.11
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 5.1
Differential gene expression profiles in imatinib-resistant cell lines 5.07
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 5.03
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 5.02
Gene expression changes in HSV-1 infected HeLa cells with knockdown of B2M 5.0
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 5.0
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 4.99
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression 4.99
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq] 4.99
MeRIP-seq for heat shock in B-cell lymphoma cells 4.97
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 4.94
Gene Expression Profiling of WT and KDM3A Knocked out Cell 4.94
DART-seq: an antibody-free method for global m6A detection 4.93
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 4.93
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 4.93
TT-Seq captures the human transient transcriptome 4.92
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia (RNA-Seq) 4.84
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia 4.84
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 4.82
Role of COP1 on MAP kinase transcriptional output in melanoma 4.79
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 4.78
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 4.77
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 4.77
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 4.75
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 4.75
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 4.71
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 4.68
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 4.67
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 4.66
miRNAs affected by antagomiR-17 treatment 4.66
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 4.64
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 4.64
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 4.62
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 4.6
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 4.51
Inhibition of TNBC metastasis by Gpx1 4.5
Primate transcript and protein expression levels evolve under compensatory selection pressures 4.48
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 4.46
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 4.41
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 4.41
Stem and effector CD8 T-cells from human cancers 4.4
Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis 4.4
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 4.35
Endothelial gene expression analysis 4.35
Transcriptome Profiling of Human Primary Monocytes 4.34
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 4.31
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 4.3
A transcriptome dataset revealing the molecular features of breast cancer stem cells 4.25
Expression analysis of genes modulated after knock-down of lncRNA CHROME. 4.25
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 4.24
Characterization of human ILC2 subsets 4.23
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 4.23
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 4.22
Functional role of CPPED1 in trophoblasts. 4.19
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 4.18
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 4.14
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 4.14
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 4.13
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 4.13
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 4.1
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 4.1
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 4.09
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 4.08
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 4.07
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 4.07
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 4.04
High-throughput sequencing of pluripotent cells 4.02
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 4.01
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 4.0
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 3.98
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 3.98
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.98
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 3.98
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 3.96
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 3.96
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 3.95
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 3.95
RNA-seq of IL-4 stimulated human keratinocytes 3.94
LncRNA expression profiling of ischemic stroke patients 3.94
Transcriptional effect of ETV1 knockdown in melanoma cells 3.92
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 3.81
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 3.81
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 3.76
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 3.76
Illumina Total RNA-seq in HeLa 3.75
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 3.75
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 3.72
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 3.71
Comprehensive comparative analysis of 5’ end RNA sequencing methods 3.7
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 3.68
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 3.64
Human embryonic stem cells in E8 and AKIT culture medium 3.64
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 3.61
RNA-seq of Human neck of femur (NOF) fracture hip and osteoarthritic (OA) cartilage 3.6
Long noncoding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells 3.6
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 3.6
RNA editing in nascent RNA affects pre-mRNA splicing 3.59
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 3.53
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 3.53
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 3.51
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 3.5
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 3.5
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 3.49
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues [Total RNA] 3.48
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 3.47
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 3.43
mRNA expression in human DAOY cells 3.42
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 3.4
Microprocessor mediates transcription termination in long noncoding microRNA genes 3.39
Identification of transcription start sites for human A549 cell line using ReCappable-seq 3.37
RNA-seq analysis of AML cells in response to ASLAN003 3.33
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 3.32
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 3.27
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 3.27
RNA-sequencing of human liver tissue 3.27
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 3.26
The effect of insulin on mRNA transcription of human pluripotent stem cells 3.25
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 3.23
RNA-seq of shEZH2 cells 3.11
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 3.09
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 3.09
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 3.07
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 3.06
Expression profiling of MCF-7 cells with treatment of TCDD 3.06
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 3.04
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 3.04
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 3.03
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 2.99
Characterizing the Chemoresistant Ovarian Cancer Population using the Heterogeneous PDX 2.98
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 2.97
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 2.97
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 2.97
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 2.94
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 2.93
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 2.91
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 2.9
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 2.9
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 2.89
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 2.88
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 2.88
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 2.86
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 2.85
Induced DNA demethylation, genome instability and transcription 2.84
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 2.84
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 2.81
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 2.78
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 2.78
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 2.77
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 2.76
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 2.73
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 2.71
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 2.7
Effect of PRDM11 depletion in U2932 cells 2.68
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 2.67
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 2.66
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 2.63
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 2.58
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 2.53
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 [RNA-Seq] 2.52
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 2.52
MAIT cell RNA sequencing 2.52
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 2.51
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 2.48
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 2.43
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 2.43
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 2.4
Hijacking of stress response machinery by oncogenes in acute leukaemia 2.39
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 2.39
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 2.35
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 2.35
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 2.35
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 2.33
RNA sequencing of human mammary epithelial cells 2.29
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 2.27
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 2.26
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 2.26
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 2.25
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 2.25
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 2.25
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_1A_PI3K_RNA-seq] 2.24
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 2.2
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 2.2
Allogeneic mature human dendritic cells generate superior alloreactive regulatory T cells in the presence of IL-15 2.18
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 2.17
Single-cell analysis of human kidney organoids 2.16
RNA-seq differential expression studies: more sequence, or more replication? 2.13
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 2.12
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 2.11
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 2.1
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 2.1
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 2.08
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 2.04
Dilated cardiomyopathy vs Myocarditis 2.03
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 2.01
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 2.01
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 1.97
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 1.97
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 1.96
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 1.96
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 1.94
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 1.93
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.91
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 1.91
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 1.91
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 1.9
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 1.9
Comparative Analysis of Cas9 Activators Across Multiple Species 1.85
Conservative alteration of chromosomal expression pattern across human solid tumor types 1.8
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 1.8
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 1.79
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 1.76
Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection 1.76
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 1.75
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 1.7
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 1.65
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 1.63
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 1.62
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 1.62
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 1.61
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway 1.6
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.59
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 1.58
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 1.58
The role of the Calcium-Sensing receptor in colorectal cancer 1.56
KSDM1b Role in Ewing Sarcoma 1.54
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 1.51
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 1.47
The Genetic Landscape of Diamond-Blackfan Anemia 1.47
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 1.47
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 1.45
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 1.44
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 1.4
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 1.4
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 1.38
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 1.38
Ectoderm specification of H1 human embryonic stem cells 1.38
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 1.36
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 1.34
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 1.32
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.31
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 1.3
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 1.29
The circadian transcriptional landscape in primary human mammary epithelial cells 1.26
Disruption of GRIN2B impairs differentiation in human neurons 1.22
Genome-wide expression from the esophageal biopsies of subjects with and without eosinophilic esophagitis 1.17
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 1.17
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 1.16
Regulating Interleukin-2 activity with engineered receptor signaling clamps 1.14
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 1.12
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.05
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.05
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 1.04
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 1.02
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 1.02
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 1.0
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.99
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 0.97
Identification of a LIF-responsive replication-competent human β cell 0.96
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 0.92
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 0.91
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 0.9
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 0.9
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 0.89
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 0.86
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 0.84
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 0.81
Gene expression and genome-wide location analysis of breast cancer cell-lines 0.77
Gene expression analysis of breast cancer cell-lines 0.77
Metabolism as an early predictor of DPSCs aging 0.75
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 0.75
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 0.74
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 0.74
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 0.73
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 0.73
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 0.72
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 0.71
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism: Liver RNA profiles of lean non-diabetic, obese non-diabetic as well as obese diabetic humans. 0.7
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. 0.7
RNA Seq of Alagille liver biopsies 0.69
Alagille_Nodder 0.69
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 0.67
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.66
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.66
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 0.65
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 0.65
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.64
Integrated epigenomic and transcriptomic profiling of terminal human erythropoiesis [TMCC2] 0.6
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 0.6
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 0.58
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 0.57
U2AF1 mutations alter splice site recognition in hematological malignancies 0.56
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 0.56
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 0.55
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 0.54
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 0.53
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.51
quanTIseq: quantifying immune contexture of human tumors 0.51
Transcriptomic Analysis Of circRNAs/miRNAs/mRNAs upon Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection 0.5
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 0.5
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.47
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 0.47
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 0.47
Co-regulation of splicing by Rbfox1 and hnRNP M 0.47
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 0.47
Chromatin-informed inference of transcriptional programs in gynecologic cancers 0.46
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 0.46
Canonical and non-canonical regulatory roles of androgen receptor variant 7 in prostate cancer 0.45
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 0.44
Regulatory network controlling tumor-promoting inflammation in human cancers 0.44
Regulatory network controlling tumor-promoting inflammation in human cancers [RNA-seq] 0.44
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 0.44
Identification of miRNA-mRNA regulatory network for Human Atrial Aging [mRNA] 0.44
Identification of miRNA-mRNA regulatory network for Human Atrial Aging 0.44
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.41
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 0.38
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.38
Intrinsic Plasma Cell Differentiation Defects in BENTA Patient B cells 0.36
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 0.3
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 0.29
The bromodomain protein BRD4 regulates splicing during heat shock 0.25
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.25
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 0.22
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction [RNA-seq] 0.19
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction. 0.19
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 0.19
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 0.17
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 0.16
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 0.16
RNA-Seq from human ILC transitional populations 0.16
mRNA recovered upon RNF219 IP. [RNA-IP] 0.15
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 0.15
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 0.15
Zone dependent distinctive gene expression profile of the normal human liver tissue 0.15
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 0.14
Loss of CREBBP results in gene expression repression in lymphoma cells 0.13
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 0.13
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 0.11
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.1
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 0.08
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 0.07
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 0.05
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.04
The role of m6A/m-RNA methylation in stress response regulation 0.04
ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq) 0.04
The MEF2B Regulatory Network 0.03
The MEF2B Regulatory Network - RNA-seq data 0.03
LIN28A modulates splicing and gene expression programs in breast cancer cells 0.02
LIN28A modulates splicing and gene expression programs in breast cancer cells [RNA-Seq] 0.02
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.02
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.02
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.01


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