Gene Query: CACTIN

Dataset Description Geneva Score
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 11.62
METTL3 promotes translation in human cancer cells 11.18
ETV7 and interferon response 10.92
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 10.92
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 10.71
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 10.49
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 10.4
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 10.31
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 10.17
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 10.1
Transcriptome analysis of SKI knock-out in HL60 cells 10.1
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 9.89
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 8.92
DART-seq: an antibody-free method for global m6A detection 8.49
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 7.98
EWSR1 influences alternative splicing through direct and indirect mechanisms 7.8
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 7.7
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 7.5
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 7.43
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 6.99
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 6.76
The evolution of N6-methyladenosine in primates 6.59
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 6.39
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 6.39
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 6.37
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 6.28
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 6.16
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 6.03
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 5.98
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 5.9
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 5.9
Gene expression profiling of leukemia cells following asparagine depletion 5.86
Differential gene expression of human melanoma cells [RNA-seq] 5.85
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 5.85
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 5.83
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 5.81
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 5.78
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 5.77
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 5.76
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 5.75
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 5.75
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 5.71
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 5.71
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 5.7
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 5.67
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 5.66
High-throughput sequencing of pluripotent cells 5.66
Small-molecule targeting of brachyury transcription factor addiction in chordoma 5.64
Effect of ILF3 on translation during homeostasis and the antiviral response 5.44
UV_24h_GRO-Seq 5.26
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 5.18
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 5.18
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 5.14
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 5.12
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 5.09
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 4.99
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 4.99
Nrf2 regulated genes in A549 cells 4.98
Identification of Nrf2 regulated genes by RNA sequencing 4.98
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 4.98
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 4.97
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 4.92
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 4.92
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 4.89
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 4.89
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 4.85
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 4.76
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 4.75
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 4.73
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 4.71
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 4.71
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 4.67
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 4.66
Mapping interactions for the TNIP2 hub protein 4.63
U1 snRNP telescripting regulates size-function stratified human genome 4.63
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 4.58
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 4.54
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 4.43
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 4.29
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 4.28
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 4.24
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 4.2
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 4.2
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 4.16
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 4.1
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 4.1
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 4.06
LncRNA-GAS5 negative regulation of YAP-target genes expression 4.05
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 4.04
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 4.04
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 4.03
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 4.0
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 4.0
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 4.0
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 3.99
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 3.99
R430: A potent inbibitor of DNA and RNA viruses 3.99
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 3.95
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 3.93
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 3.93
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 3.93
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 3.93
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 3.92
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 3.91
Cajal bodies are linked to genome conformation 3.87
Cajal bodies are linked to genome conformation [RNA-Seq] 3.87
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells 3.86
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2) 3.86
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 3.81
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 3.79
Impact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST 3.78
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 3.78
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 3.77
Effect of PRDM11 depletion in U2932 cells 3.76
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 3.75
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 3.75
MOF acetyl transferase regulates transcription and respiration in mitochondria 3.74
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 3.73
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 3.73
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 3.69
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 3.64
An integrative network biology analysis identifies miR-508-3p as the determinant and a prognosis biomarker of the mesenchymal subtype ovarian cancer 3.63
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 3.6
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 3.6
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 3.57
Accurate annotation of human protein-coding small open reading frames 3.57
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 3.55
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 3.54
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 3.51
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 3.51
NKX2.2 3.51
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 3.51
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 3.5
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 3.46
Mutational landscape of splicing genes and functional consequences across 33 cancer types 3.45
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 3.44
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 3.43
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 3.43
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 3.43
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 3.42
Selective suppression of endothelial cytokine production by progesterone receptor 3.42
Selective suppression of endothelial cytokine production by progesterone receptor [RNA-seq] 3.42
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 3.41
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 3.39
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 3.38
Seletive inhibition of CDK9 in DLBCL cell lines 3.37
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 3.35
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 3.34
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 3.34
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 3.32
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 3.32
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 3.32
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 3.31
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 3.28
RNA-seq of cells with TET1 knockout 3.26
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 3.26
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 3.24
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 3.24
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 3.24
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 3.24
Gene expression in GBM with Cav3.2 inhibition 3.2
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 3.19
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 3.17
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 3.17
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 3.14
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 3.08
Profiling of escape kinetics of viruses subjected to RNAi 3.06
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 3.05
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 3.02
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 3.01
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 3.01
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 3.0
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 2.99
Transciptomic profiling of human fetal lung samples 2.97
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 2.96
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 2.96
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 2.94
Gene expression analysis of the impact of TDP-43 knockout in human cells. 2.92
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 2.91
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 2.89
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 2.88
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 2.88
RNAseq of HEK293 cells after Chtop knockdown 2.88
Co-transcriptional loading of RNA export factors shapes the human transcriptome 2.88
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 2.85
Genetic disruption of COX-1 inhibits multiple oncogenic pathways 2.85
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 2.85
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 2.84
RNA-seq of shEZH2 cells 2.84
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 2.84
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 2.84
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 2.83
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 2.83
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 2.82
SETBP1-WT and SETBP1-G870S epigenetic landscapes 2.82
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 2.81
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 2.81
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 2.79
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 2.79
Genome-wide discovery of human splicing branchpoints [RNAse] 2.76
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 2.72
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 2.7
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 2.68
Hepatitis C virus functionally sequesters miR-122 2.68
RNA-Seq of CD4+ T cells treated with AS1842856 or DMSO 2.67
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 2.67
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 2.66
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 2.66
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 2.64
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 2.64
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 2.63
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 2.63
High-Throughput Kinetic Analysis of Fractional Killing 2.63
RNA sequencing of mechanically strained NHEKs and control NHEKs 2.59
snRNAs as regulators of alternative splicing 2.59
IDH3a KO RNA-seq 2.58
Paxillin regulates genomic networks in prostate cancer [PC3] 2.57
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 2.56
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 2.54
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 2.54
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 2.53
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 2.52
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 2.51
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 2.48
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 2.46
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 2.46
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 2.45
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 2.41
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 2.4
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 2.39
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 2.38
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 2.36
Transcriptome Profiling of Human Primary Monocytes 2.35
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 2.34
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 2.32
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 2.28
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 2.26
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 2.26
RNA splicing alteration on glioblastoma and normal neural stem cells 2.24
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 2.23
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 2.21
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 2.21
Functional role of CPPED1 in trophoblasts. 2.2
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 2.17
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 2.17
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 2.17
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 2.14
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 2.14
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 2.14
Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues 2.13
Capturing the Interactome of Newly Transcribed RNA (RICK) 2.11
Capturing the Interactome of Newly Transcribed RNA 2.11
Parallel T-cell cloning and deep sequencing of the transcripts of human MAIT cells reveal stable oligoclonal TCRβ repertoire 2.11
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 2.09
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 2.09
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 2.08
The mRNA expression analysis of psoriasis skin lesion mesenchymal stem cell 2.07
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 2.07
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 2.06
PRDM1 inhibits proliferation of human colon cancer organoids 2.05
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 2.05
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 2.05
Gene expression regulated by CSA and CSB in neuroblastoma cell line 2.05
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 2.03
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 2.03
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 2.03
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 2.03
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 2.01
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 2.01
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 2.0
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 2.0
A20 regulates canonical wnt-signaling through an interaction with RIPK4 1.96
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 1.96
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 1.95
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 1.95
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 1.94
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 1.94
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 1.93
RNA-seq analysis of control and Myc-induced U2OS cells 1.93
Studying the selectivity of a small molecule Synucleozid on transcriptome 1.89
Patient-derived luminal breast cancer xenografts with progestins 1.87
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 1.87
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 1.85
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 1.82
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 1.78
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 1.77
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 1.77
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 1.77
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 1.73
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 1.72
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 1.71
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 1.71
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 1.67
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 1.66
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 1.66
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 1.65
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 1.65
Targeted enhancer activation by a subunit of the integrator complex 1.63
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 1.61
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 1.61
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 1.6
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 1.59
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 1.59
Retinoic acid suppresses MYB in adenoid cystic carcinoma 1.59
Retinoic acid suppresses MYB in adenoid cystic carcinoma [RNA-seq] 1.59
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 1.58
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 1.58
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 1.58
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 1.58
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 1.57
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 1.55
Exploring ILF2 regulatory genes by next-generation sequencing 1.55
Genome-wide discovery of human splicing branchpoints 1.54
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 1.51
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 1.5
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 1.5
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 1.47
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 1.47
Downregulation of LATS kinases alters p53 to promote cell migration 1.46
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 1.46
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 1.45
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 1.45
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 1.45
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 1.44
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 1.44
Global Mapping of Human RNA-RNA Interactions 1.41
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 1.41
Subtle asymmetry of gene expression in embryonic and foetal human brains 1.36
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.35
ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex 1.35
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 1.33
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 1.3
FBXW7 modulates stress response by post-translational modification of HSF1 1.3
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 1.3
A transcriptome-wide divergence in protein translation scales with LIN28B expression 1.3
Dysregulated immune system networks in war veterans with PTSD 1.29
Regulation of poly(A) tail and translation during the somatic cell cycle 1.28
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 1.27
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 1.26
Clinker: visualizing fusion genes detected in RNA-seq data 1.26
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 1.22
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 1.22
RNA-seq analysis of differentiating human erythroblasts 1.21
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 1.21
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 1.21
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 1.21
CD86 regulates a pro-survival signal in myeloma cells 1.2
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 1.2
HEK293 Heat-shock experiment 1.19
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 1.18
Differential responses of human fetal brain neural stem cells to Zika virus infection 1.18
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 1.17
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 1.17
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 1.11
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 1.11
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.1
Functional significance of the HIV-1 Tat signature amino acid residues 1.07
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 1.04
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 1.04
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 1.04
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 1.03
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 1.03
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 1.01
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.0
RNA-seq data from human lymphoma cell lines 1.0
ChIP-seq and RNA-seq from human lymphoma cell lines 1.0
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 0.99
SRSF1 role in cellular gene expression and splicing 0.98
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.98
RNA-Seq analysis of HIF-2a-responsive genes in clear-cell renal cell carcinoma 0.97
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 0.97
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 0.95
Real-time observation of light-controlled transcription in living cells 0.95
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 0.94
Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation 0.92
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 0.91
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.9
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 0.9
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 0.9
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 0.89
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.89
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.88
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 0.88
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 0.86
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 0.85
H1609088 Human RNA-Sequencing 0.84
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 0.82
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 0.82
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 0.82
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 0.78
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 0.77
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 0.76
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors 0.75
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 0.75
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 0.74
RNA-seq of exosomes identifies lncRNA profiles that distinguish early-stage esophageal squamous cell carcinoma (ESCC) from non-malignant esophagitis 0.74
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 0.73
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.73
quanTIseq: quantifying immune contexture of human tumors 0.71
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 0.69
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 0.69
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.69
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.68
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.68
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 0.67
Tracing Enhancer Networks using Epigenetic Traits (TENET) 0.66
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 0.65
X-Ray induced DNA-Hydroxymethylation changes 0.65
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 0.65
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.62
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 0.62
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 0.62
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 0.62
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.62
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.6
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 0.59
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 0.58
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 0.58
naive T cell heterogeneity after neonatal thymectomy 0.56
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 0.55
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 0.55
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 0.55
Silencing SPIB in attached and floating state of H1703 lung cancer cells 0.54
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 0.54
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 0.54
Metabolism as an early predictor of DPSCs aging 0.51
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 0.5
Polarized B -cell functions 0.49
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 0.49
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 0.49
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 0.49
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 0.47
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 0.43
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 0.42
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 0.42
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.42
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 0.42
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 0.4
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 0.4
The role of m6A/m-RNA methylation in stress response regulation 0.4
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.4
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.39
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.39
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 0.39
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.37
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 0.36
Investigate A2M treatment on human prostate cancer and mouse liver 0.36
Investigate A2M treatment on human prostate cancer xenograft in mice 0.36
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 0.35
Glioblastoma stem cells infected by ZIKA virus 0.35
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 0.31
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.3
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.3
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 0.29
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 0.29
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 0.29
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 0.29
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.26
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 0.25
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 0.22
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 0.22
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.22
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 0.21
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 0.21
Trnascriptome analysis of HeLa cells infected with rTHOV-wt, -dML, -SW mutant or mock-treated 0.21
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.21
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 0.19
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 0.18
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 0.17
Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia 0.16
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.16
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 0.15
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.15
Canonical and non-canonical regulatory roles of androgen receptor variant 7 in prostate cancer 0.15
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.12
Novel Non-catalytic Substrate-selective p38α-specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-inflammatory Activity 0.12
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 0.12
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 0.11
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 0.11
Ribosomal protein RPL26 is the principal target of UFMylation 0.11
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.1
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 0.1
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 0.08
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 0.07
circNFIB suppresses lymphatic metastasis of pancreatic cancer 0.06
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.06
Function and hormonal regulation of GATA3 in human first trimester placentation 0.06
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 0.05
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 0.05
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 0.04
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 0.04
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.04
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.04
RNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls 0.03
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.03
BACH2 in human plasma cell fate decision 0.01
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 0.01
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.0
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 0.0
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 0.0


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation