Gene Query: CDC40

Dataset Description Geneva Score
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 22.11
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 16.32
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 13.82
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 13.23
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 12.74
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 11.67
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 10.84
Unique features and clinical importance of acute alloreactive immune responses 10.77
R430: A potent inbibitor of DNA and RNA viruses 10.7
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 10.6
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 10.6
Biological effect of chronic mistranslation in mammalian cells 10.57
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 10.34
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 10.25
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 9.87
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 9.17
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 9.17
Characterization of sperm lncRNA and its differently expression in the sperm of asthenozoospermic patients 8.86
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 8.83
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 8.83
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 8.81
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 8.76
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 8.62
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 8.59
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 8.59
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 8.56
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 8.49
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 8.47
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 8.47
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 8.3
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 8.3
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 8.17
CROP-Seq in Primary Human T Cells 8.14
Identification of monocyte-like precursors of granulocytes as a mechanism for accumulation of PMN-MDSC in cancer 8.02
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 7.67
Tracking distinct RNA populations using efficient and reversible covalent chemistry 7.63
Global Mapping of Human RNA-RNA Interactions 7.57
Gene expression in PANC1 cells treated with Rakicidin 7.17
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 7.0
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 7.0
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 6.98
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 6.96
Seletive inhibition of CDK9 in DLBCL cell lines 6.89
Transcriptomes of human monocytes after ex vivo exposure to uric acid 6.87
Transcriptome-wide identification of CELF2 functional targets in T cells 6.44
Transcriptome analysis of SKI knock-out in HL60 cells 6.44
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 6.44
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 6.38
WRN knockout effects upon gene expression in SW48 and OVK18 6.34
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 6.32
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 6.32
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 6.27
Integrating single-cell transcriptomic data across different conditions, technologies, and species 6.27
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 6.23
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 6.22
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 6.22
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 6.21
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 6.18
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 6.09
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 6.02
scRNASeq analysis of cycling cardiomyocytes 5.91
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 5.87
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 5.87
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 5.78
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 5.76
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 5.72
EWS-Fli and LNC regulated genes in comparison to GFP samples 5.68
Antibody-Mediated Inhibition of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity 5.68
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 5.61
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 5.6
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 5.6
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 5.6
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 5.58
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 5.56
Human cell line and subcutaneous tumor 5.53
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 5.49
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 5.47
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 5.42
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 5.39
ARID1A regulates condensin II distribution and chromosomal partition [RNA-seq] 5.38
ARID1A regulates condensin II distribution and chromosomal partition 5.38
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.34
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 5.28
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 5.28
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 5.26
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 5.19
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 5.19
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 5.18
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 5.16
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 5.11
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 5.11
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 5.09
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 5.06
Crizotinib v. DMSO in SW480 cells 5.02
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 5.01
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 4.92
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 4.89
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 4.88
Identification of renal resident macrophages across species 4.88
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 4.86
Total RNA-seq in ALL-SIL upon TLX1 knockdown 4.84
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 4.84
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 4.82
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 4.81
Effect of PRDM11 depletion in U2932 cells 4.8
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 4.74
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 4.68
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 4.65
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 4.61
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 4.6
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 4.59
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 4.58
The Genetic Landscape of Diamond-Blackfan Anemia 4.56
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 4.53
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 4.53
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 4.48
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 4.48
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 4.46
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 4.44
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 4.44
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 4.38
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 4.37
Knockdown of ADNP in HCT116 colon cancer cells 4.28
4.27
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 4.25
ETV7 and interferon response 4.25
RNAseq analysis of ESRP regulated splicing events in prostate cancer 4.25
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 4.25
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 4.22
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 4.22
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 4.19
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 4.19
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 4.19
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 4.19
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 4.18
single cell RNA-seq from GM12878 (ENCSR673UIY) 4.15
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 4.13
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing 4.12
Targeting MTHFD2 in Acute Myeloid Leukemia 4.11
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 4.09
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 4.07
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 4.04
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 4.03
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 4.02
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 3.94
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 3.92
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 3.92
Expression by CD133+ cells isolated from the adult human exocrine pancreas 3.88
Genome wide miR-191 target profile determined by RIP and gene expression profiling 3.88
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 3.88
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 3.87
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 3.85
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 3.84
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 3.84
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 3.82
MYC dependent mRNA translation shapes gene expression and cell biology 3.82
Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines 3.81
RNA-seq analysis of Retinoic Acid and Non-treated Control hiPSCs 3.8
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 3.79
Global analysis of enhancer targets: Mosaic-seq 3.76
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 3.76
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 3.76
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 3.74
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 3.73
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 3.72
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 3.68
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 3.68
Generating Patterned Kidney Organoids for Studying Development and Diseases 3.67
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 3.64
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 3.62
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 3.6
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 3.6
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 3.59
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons 3.57
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 3.56
Single-cell RNA-seq reveals novel cell differentiation dynamics during human airway epithelium regeneration 3.56
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 3.54
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 3.52
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 3.52
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 3.52
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 3.51
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 3.51
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 3.49
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 3.47
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 3.46
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 3.46
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 3.46
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 3.45
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 3.45
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 3.44
B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis 3.43
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 3.43
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 3.41
RNA-seq analysis of differentiating human erythroblasts 3.41
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 3.41
mRNA expression profile of Lymphocytes 3.39
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 3.39
Single-cell analysis of human kidney organoids 3.39
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 3.38
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 3.35
Allelic expression mapping across cell lineages reveal repressor disruption among disease SNPs 3.3
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 3.29
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 3.29
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 3.29
HNF1A deficiency impairs β-cell fate, granule maturation and function 3.29
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 3.27
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 3.25
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 3.25
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 3.25
Tpl-2 and MEK small molecule inhibitors 3.22
Tpl-2 small molecule project 3.22
Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs) 3.2
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 3.2
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 3.19
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 3.19
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 3.19
Chromatin-informed inference of transcriptional programs in gynecologic cancers 3.19
mRNA Sequencing of Human PromoCells Using 3'-directed Digital Gene Expression (3'-DGE) Technique 3.17
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 3.16
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 3.15
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 3.15
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 3.13
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 3.12
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 3.11
O-glcnAc reprograms cellular energetics 3.09
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 3.09
Be1 and Be2 B cells are transcriptionally distinct 3.08
Exploring the role of macroH2A1 in transcription regulation in IMR90 primary human lung fibroblasts with RNA-seq and ChIP-seq 3.08
RNA-seq from control and macroH2A1-depleted IMR90 primary human lung fibroblasts 3.08
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 3.03
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 3.02
Genome-wide analysis of the Integrator complex 2.98
Genome-wide analysis of the Integrator complex (HTS) 2.98
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 2.98
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 2.98
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 2.97
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 2.96
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 2.94
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 2.93
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 2.93
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 2.92
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 2.92
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 2.82
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 2.79
Transcriptional profile in human S. haematobium infection 2.76
Controlling for gene expression changes in transcription factor protein networks. 2.73
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 2.73
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 2.73
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 2.72
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 2.72
A sister of NANOG regulates genes expressed in pre-implantation human development 2.69
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 2.69
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 2.67
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 2.66
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 2.66
Transcriptome Profiling of Human Primary Monocytes 2.64
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 2.64
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 2.64
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 2.61
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 2.6
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 2.59
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  2.58
Human Treg NaCl stimulation 2.58
The Wnt/β-catenin and RAS-ERK Pathways were Activated in Tissues of Chemotherapy-Resistant Gastric Cancer PDX Tumor 2.57
Gene expression profiling of leukemia cells following asparagine depletion 2.57
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 2.52
MYCL and EP400 are required for Max and MCPyV mediated gene activation 2.52
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 2.5
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 2.49
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 2.48
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 2.44
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 2.38
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 2.38
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 2.38
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 2.38
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 2.36
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 2.36
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 2.34
Mutations in EBF3 disturb transcriptional profiles and cause intellectual disability, ataxia and facial dysmorphism 2.3
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 2.28
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 2.25
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 2.24
PRDM1 inhibits proliferation of human colon cancer organoids 2.23
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 2.21
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 2.19
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 2.19
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 2.14
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 2.11
RNA sequencing of primary human platelets and in vitro cell lines 2.05
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 2.04
Transcriptome of human ILC2s; primary vs IL-1b-primed 2.04
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 2.04
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 2.04
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 2.03
Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing 2.0
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 1.95
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 1.94
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 1.94
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 1.93
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 1.89
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 1.89
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 1.87
RNA-seq data 1.87
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 1.86
Gene expression signatures of innate lymphoid cells from human blood 1.85
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 1.84
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 1.83
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with pancreatic carcinoma 1.83
Systematic discovery of endogenous human ribonucleoprotein complexes 1.83
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 1.81
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 1.8
Transcriptomes of oxLDL exposed trained monocytes 1.8
oxLDL exposed trained monocytes 1.8
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 1.8
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [human] 1.77
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug 1.77
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 1.74
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 1.74
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 1.72
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 1.72
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 1.69
Transcriptome of U251 cells overexpression complement component 7 1.69
Conservative alteration of chromosomal expression pattern across human solid tumor types 1.68
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 1.68
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.68
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 1.66
CD74 role in transcription regulation 1.66
CD74 role in transcription regulation [RNA-seq] 1.66
Genetic-to-epigenetic Therapy for Pancreatic Cancer 1.65
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 1.64
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 1.63
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 1.63
SOX11 knockdown in B-ALL cell lines 1.62
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 1.61
The cohesin release factor WAPL restricts chromatin loop extension. 1.61
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 1.61
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 1.57
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.57
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.55
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 1.55
RNAseq in Alzheimer's Disease patients 1.54
TOP2B disturbed the quality of human oocytes with advanced maternal age 1.53
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 1.53
Transcriptomic analysis of human tonsillar TFH subsets 1.5
Total RNA-Seq data from leukemic patients with complex structural variants 1.49
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 1.47
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 1.46
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 1.44
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.44
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.43
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 1.41
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 1.39
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with colorectal carcinoma 1.33
Epigenetic reprogramming of melanoma cells by vitamin C treatment 1.32
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways 1.3
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 1.3
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 1.3
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 1.3
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 1.28
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 1.25
LIN28A Over-expression RNAseq 1.24
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 1.23
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 1.23
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 1.23
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 1.23
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 1.23
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 1.2
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 1.2
Discovering human diabetes-risk gene function with genetics and physiological assays 1.19
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 1.19
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.19
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 1.18
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.18
Analyses of T-ALL (COG study) 1.17
RNA sequencing of T-ALL (COG study) 1.17
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 1.17
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 1.16
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 1.15
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 1.14
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 1.13
Gene expression profiling of human iPS cell-derived podocytes and sorted human adult podocytes 1.11
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 1.1
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 1.09
Human ovarian granulosa cell transcriptome 1.09
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 1.08
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 1.08
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 1.08
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 1.07
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 1.07
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 1.07
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 1.06
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 1.05
Generation and persistence of human tissue-resident memory T cells in lung transplantation 1.03
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 0.97
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.96
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 0.96
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 0.96
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 0.95
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 0.95
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 0.94
Global transcriptome analysis of WT versus HEB-/- hESCs 0.93
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.91
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 0.91
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 0.91
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 0.88
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 0.86
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 0.86
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.86
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 0.85
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 0.85
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 0.85
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 0.85
KSDM1b Role in Ewing Sarcoma 0.83
Transcriptome analysis of peripheral blood monocytes 0.82
Specific molecular signatures underlie response to decitabine in CMML 0.81
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.81
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 0.79
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 0.78
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 0.77
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 0.77
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 0.77
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 0.76
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 0.76
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 0.76
Peptidomimetic blockade of MYB in acute myeloid leukemia 0.75
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 0.75
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.74
Function and hormonal regulation of GATA3 in human first trimester placentation 0.72
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 0.72
Interaction between mitoNEET and NAF-1 in cancer cells 0.71
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 0.7
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 0.7
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.68
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 0.65
Functional significance of the HIV-1 Tat signature amino acid residues 0.64
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [Primary RNA-Seq] 0.63
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.63
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 0.62
Transcriptional landscape changes during human embryonic stem cell derivation 0.59
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.57
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 0.56
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.55
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.54
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 0.53
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 0.53
Single Cell RNASeq profiling of stromal vascular fraction from Subcutaneous and visceral adipose tissue 0.52
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 0.51
Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection 0.5
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 0.5
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 0.5
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.49
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.48
Aging-associated patterns in the expression of human endogenous retroviruses 0.47
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 0.46
ML29755 RNA-seq data 0.44
Role of cervicovaginal microbiota in genital inflammation 0.43
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 0.43
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 0.42
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 0.42
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 0.41
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.4
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.4
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 0.39
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 0.39
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 0.37
Next generation sequencing of small RNAs isolated from exosomes in human semen 0.34
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.34
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.32
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.32
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.3
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 0.3
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.28
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.26
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 0.25
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 0.23
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 0.23
RNA-seq of primary patient AML samples 0.22
Transcriptome of diurnal human blood neutrophils 0.22
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 0.21
Modulation of nonsense-mediated decay by rapamycin 0.2
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.19
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.18
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.17
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 0.15
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.15
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.13
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.13
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.12
DAOY-Notch1/Notch2 knockout: transcriptome comparison 0.09
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 0.09
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.08
Transcriptomic analysis of LSD1 0.07
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 0.07
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 0.06
RNA seq analysis of human Fetal and adult derived Enterospheres 0.06
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.05
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.04
Tracking transcriptional changes in a species-specific manner during experimental hepatoblastoma progression in vivo 0.02
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 0.01
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 0.0


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