Gene Query: CDK5RAP3

Dataset Description Geneva Score
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 100.94
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 67.11
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 62.43
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 47.91
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 44.56
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 40.62
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 37.15
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 33.3
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 32.35
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 32.23
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 29.82
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 28.76
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 28.76
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 28.12
Transcriptional profiling of LS1034 cells treated with tepoxalin 25.87
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 25.7
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 25.61
Effect of Influenza virus infection on lncRNA expression in A549 cells 25.55
RNA-seq of IL-4 stimulated human keratinocytes 25.52
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 24.92
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 24.89
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 24.46
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 23.85
A transcriptome-wide divergence in protein translation scales with LIN28B expression 22.16
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 21.75
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 21.38
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 21.38
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 21.31
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 19.61
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 19.5
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 19.24
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 18.46
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 17.61
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 17.5
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq] 17.36
Differentiation enhances Zika virus infection in neuronal brain cells 17.34
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 16.73
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 16.44
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 16.43
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 16.23
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 16.23
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 16.19
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 15.93
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons 15.87
Primary human trophoblast from term placenta 15.87
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 15.83
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 15.69
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 15.68
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 15.61
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 15.57
Biological effect of chronic mistranslation in mammalian cells 15.31
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 14.95
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 14.79
Active translatome profiling with RiboLace in MCF7 cells 14.65
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 14.53
Paxillin regulates genomic networks in prostate cancer [PC3] 14.39
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 14.27
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 14.22
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 14.16
Intrahepatic MAIT cell gene expression revealed by RNA-seq 14.11
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 14.01
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 14.01
Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice 14.01
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 13.97
Patient-derived luminal breast cancer xenografts with progestins 13.67
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 13.67
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 13.64
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 13.59
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 13.59
Transcriptome profiling of influenza virus-infected human bronchial epithelial cells 13.32
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 13.32
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 13.32
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 13.14
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 12.99
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq] 12.93
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 12.79
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 12.75
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 12.7
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 12.59
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 12.43
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 12.43
MicroRNA-125a-5p overexpression in human macrophages 12.42
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 12.39
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 12.32
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 12.32
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 12.28
EP400 is required for Max and MCPyV mediated gene activation 12.21
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 12.21
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 12.21
IDH3a KO RNA-seq 12.15
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 12.11
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 12.03
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 12.03
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 11.96
TGF-β regulation of miRNA expression in pancreatic cancer 11.83
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 11.82
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 11.75
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 11.54
Gene expression analysis in response to hypoxic pathway inhibition 11.53
ZIKV infection of monocytes activates inflammasome pathways 11.43
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 11.35
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 11.34
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling 11.23
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 11.02
Regulation of highly expressed hCINAP on translatome 10.97
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 10.95
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 10.94
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 10.86
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 10.82
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 10.77
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 10.69
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 10.69
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 10.67
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 10.66
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 10.66
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 10.6
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 10.52
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 10.47
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 10.47
STX4 Over-Expression in Human islets 10.46
DJ-1 is dispensable for human stem cell homeostasis 10.36
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 10.21
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 10.21
RNA-seq of MCF10A cells and CAF 10.2
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 10.17
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 10.13
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 10.1
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 10.07
RNA sequencing data of whole blood cells of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women 10.03
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 10.01
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 9.99
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 9.93
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 9.91
Profiling in vivo Bone Lesion (IVBL) and Orthotopic tumors by Next Generation Sequencing 9.84
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 9.7
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 9.63
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 9.58
Short and Long RNA sequencing of human mature erythrocytes 9.5
RNA-seq of human aneuploid cell lines with Trisomy 21 9.47
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 9.38
Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a Colorectal Cancer Patient-derived Tumor Explant Model 9.38
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 9.37
Uridylation by TUT4 and TUT7 marks mRNA for degradation 9.35
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 9.25
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 9.23
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 9.23
Regulation of protein translation during mitosis 9.18
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 9.16
Gene expressions of H9s in different culture systems 9.14
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 9.12
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 9.11
MYC dependent mRNA translation shapes gene expression and cell biology 9.11
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 9.07
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 9.05
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 9.03
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 9.02
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 9.01
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 9.01
Disruption of the exocyst induces podocyte loss and dysfunction 9.01
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 8.9
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 8.9
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 8.89
Maturing an Enteric Nervous System in Human Intestinal Organoid-derived Tissue-Engineered Small Intestine 8.78
RNA-seq of YB5 cells treated with Proscillaridin A 8.74
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 8.73
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 8.72
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 8.66
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype 8.64
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 8.64
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 8.64
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 8.62
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 8.61
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 8.6
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 8.57
NRDE2 negatively regulates nuclear exosome functions 8.52
SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis 8.48
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 8.47
Transcriptome analysis of VCaP xenografts resistant to dual therapy with abiraterone and enzalutamide 8.43
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 8.43
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 8.43
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 8.43
Expression profiling of MCF-7 cells with treatment of TCDD 8.39
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 8.39
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 8.38
Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells 8.36
An optimization system for isolating and sequencing of single human colon cancer cells 8.34
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 8.32
Tumor exosome integrins determine organotropic metastasis 8.31
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 8.26
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 8.23
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 8.2
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 8.18
mRNA expression profile of Lymphocytes 8.17
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 8.16
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 8.15
SETBP1-WT and SETBP1-G870S epigenetic landscapes 8.15
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 8.12
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 8.09
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 8.09
Rorc disruption in human FG pancreatic cancer cells 7.97
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 7.89
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 7.89
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 7.88
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  7.84
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 7.83
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 7.79
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 7.79
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 7.69
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 7.68
Identification of Sin3B regulated genes during quiescence 7.6
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 7.59
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 7.55
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 7.54
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 7.51
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 7.48
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 7.47
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 7.47
TCF21 and Aryl-hydrocarbon receptor gene cooperate to activate a pro-atherosclerotic gene expression program 7.4
single cell RNA-seq from GM12878 (ENCSR673UIY) 7.32
MARCKS and lnc-MARCKS act as inflammation regulators 7.32
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 7.31
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 7.31
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 7.3
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 7.29
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 7.28
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 7.25
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 7.22
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 7.22
miR941 overexpression experiment 7.12
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 7.12
Global response to chemotherapy-induced apoptosis 7.11
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 7.11
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 7.01
Disruption of GRIN2B impairs differentiation in human neurons 7.0
Effect of PRDM11 depletion in U2932 cells 6.93
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 6.9
Illumina sequencing of vaginal epithelial cells from women using depot medroxyprogesterone acetate or non-hormonal contraception 6.85
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 6.79
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 6.77
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 6.73
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 6.7
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 6.65
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 6.59
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 6.59
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 6.55
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 6.52
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 6.49
Trascriptome of thyroid cancer-induced macrophages 6.44
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 6.39
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 6.38
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 6.34
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 6.31
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 6.27
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 6.27
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 6.22
PRDM1 inhibits proliferation of human colon cancer organoids 6.16
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 6.15
MRTF activates TEAD-YAP target gene expression 6.14
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 6.13
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 6.05
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 6.03
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 6.03
quanTIseq: quantifying immune contexture of human tumors 6.02
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 5.96
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 5.88
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 5.88
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 5.71
SLIGRL-induced gene expression changes in NHEK cells 5.68
X-Ray induced DNA-Hydroxymethylation changes 5.65
RNA splicing alteration on glioblastoma and normal neural stem cells 5.62
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 5.55
Expression analysis of genes modulated after knock-down of lncRNA CHROME. 5.53
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 5.51
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 5.51
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 5.48
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 5.48
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 5.46
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 5.46
Differential Gene Expression between MCF10A and MCF7 cells 5.42
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 5.38
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I 5.38
Expression by CD133+ cells isolated from the adult human exocrine pancreas 5.37
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 5.36
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 5.34
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 5.34
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 5.34
TAF1 is critical for AE driven leukemogenesis 5.3
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 5.3
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 5.23
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 5.23
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 5.23
Transcriptomics analysis of enteroendocrine cells following vertical sleeve gastrectomy 5.22
Transcriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy 5.22
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 5.19
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 5.19
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 5.18
RNA-Seq from human ILC transitional populations 5.18
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 5.15
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 5.15
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 5.13
mRNA sequencing analysis of cultured human primary airway epithelial cells upon exposure to PMN exosomes 5.12
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 5.11
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 5.06
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 5.06
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 4.98
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 4.92
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 4.85
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 4.84
High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues 4.81
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 4.81
FOXA1 Chromatin Binding is Regulated by LSD1-Mediated Demethylation 4.77
RNA-Seq with DHT induction and/or GSK treatment at 24, 48 hrs and 2 weeks 4.77
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 4.75
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 4.62
Diarrhoeal mechanisms of the Campylobacter jejuni enteritis 4.61
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 4.47
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 4.47
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 4.39
Transcriptional responses of melanoma cells to BRAF inhibition 4.37
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 4.36
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 4.33
hESC neural differentiation 4.31
RNA-seq analysis of gene expression patterns during hESC neural differentiation 4.31
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 4.28
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 4.28
Identification of global XBP1s target gene expression in human prostate cancer cells 4.25
K562 polyA RNA-Seq 4.25
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 4.24
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 4.17
Short and long-term effects of CDK4/6 inhibition on early stage breast cancer 4.12
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 4.1
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 4.04
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 4.02
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 3.99
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 3.99
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 3.97
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 3.92
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 3.9
Human cells contain natural double-stranded RNAs with potential regulatory capacity 3.87
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 3.85
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 3.83
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 3.7
Regulation of poly(A) tail and translation during the somatic cell cycle 3.69
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 3.69
Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis 3.69
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 3.67
Role of FGFR1 in neuronal devlopment 3.66
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 3.59
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 3.59
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 3.55
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 3.55
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 3.52
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 3.51
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.51
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 3.51
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 3.51
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 3.51
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 3.5
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 3.44
Mutational landscape of splicing genes and functional consequences across 33 cancer types 3.44
Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle by inducing capillary sprouting and decreasing vascular permeability via reduced eNOS activity 3.43
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 3.39
Effect of CHKA knockdown on C4-2 cell transcriptome 3.39
RNA-sequencing 3.34
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 3.16
Triple vectors expand AAV transfer capacity in the retina 3.15
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 3.06
Total RNA-Seq data from leukemic patients with complex structural variants 3.05
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 3.05
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 3.05
Comparative transcriptome analysis reveals that ECM-Receptor Interaction contributes to the venous metastases of hepatocellular carcinoma 3.03
m6A-dependent regulation of messenger RNA stability 2.98
Paclitaxel plus Cirmtuzumab Achieves Greater Clearance of Patient-derived Xenografts By Targeting ROR1+ Breast Cancer Stem Cells 2.95
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 2.93
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 2.93
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 2.92
RNA-seq analysis of primary patient samples to characterize the CNS leukemia 2.91
Transcriptome analysis of CNS leukemia 2.91
Transcriptome analysis of peripheral blood monocytes 2.85
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001 2.76
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 2.73
O-glcnAc reprograms cellular energetics 2.72
HEK293 TFAM Knockout Expression Study 2.68
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 2.58
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 2.57
Epigenetic reprogramming of melanoma cells by vitamin C treatment 2.57
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 2.52
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 2.45
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 2.45
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 2.45
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 2.45
The role of CFTR in islet function 2.44
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 2.42
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 2.37
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 2.37
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 2.37
Human embryonic stem cells in E8 and AKIT culture medium 2.35
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 2.35
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells 2.3
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 2.3
Effect of PBK knockdown on C4-2 cell transcriptome 2.3
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 2.29
Differential responses of human fetal brain neural stem cells to Zika virus infection 2.26
Methylome, hydroxymethylome, and integrative transcriptome profiling in human CRC tissue and paired normal tissues 2.26
Transcriptome sequencing of K-562 cells 2.25
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 2.24
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 2.22
Human ovarian granulosa cell transcriptome 2.13
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 2.12
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 2.08
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 2.08
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 2.07
Next Generation Sequencing identifying the dosage compensation state in human endometrial carcinoma and adjacent tissues 2.06
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 2.03
Neuronal Development And The Onset Of Electrical Activity In The Human Enteric Nervous System 2.02
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 2.01
Effects of rFVIIIFc on human macrophages 1.98
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 1.94
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 1.89
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 1.88
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 1.84
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 1.77
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 1.75
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 1.73
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 1.71
Transcriptome profiling of Cryptosporidium parvum infected lung and intestinal organoids 1.71
Tracing Enhancer Networks using Epigenetic Traits (TENET) 1.71
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 1.66
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 1.66
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 1.65
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.64
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 1.63
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 1.63
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 1.62
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 1.54
ARS2 is a general suppressor of pervasive transcription [RNAseq] 1.48
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 1.47
Stem and effector CD8 T-cells from human cancers 1.45
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 1.39
Expression profiling by RNA-Seq of breast cancer samples from patients in walnut-consuming and control groups 1.39
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 1.37
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 1.37
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 1.36
Human islets of varying quality: the good, the (not so) bad and the ugly 1.36
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 1.26
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 1.23
The role of the Calcium-Sensing receptor in colorectal cancer 1.2
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 1.2
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 1.19
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 1.15
Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection 1.13
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 1.1
Age-Related Gene Expression Changes in Prostate Cancer Patients 1.08
Age-Related Gene Expression Changes in Prostate Cancer Patients [RNA-Seq] 1.08
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 1.06
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 1.0
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2) 0.93
RNA-sequencing analysis examining how the Vibrio cholerae MARTX toxin and its inidividual effector domains modulate the transcriptome of human intestinal epithelial cells. 0.91
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 0.9
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 0.88
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 0.84
Transcriptomic profile of intestinal epithelial cells obtained from ileal endoscopic biopsies from newly-diagnosed, pediatric Crohn's disease patients and healthy controls. 0.83
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 0.81
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 0.81
BASP1 modifies the Tamoxifen response 0.78
Estrogen Receptor Beta Impacts Hormone-Induced Alternative mRNA Splicing in Breast Cancer Cells 0.74
RNA expression profiles comparing primary and omental ovarian carcinoma samples 0.73
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 0.67
The DPYSL2 gene connects mTOR and schizophrenia 0.62
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 0.6
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.49
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 0.45
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 0.44
iPSC derived motor neuron cultures from C9ORF72 carriers 0.42
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 0.39
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 0.39
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 0.35
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 0.35
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.34
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.34
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 0.33
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 0.29
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.25
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 0.24
Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft] 0.2
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 0.2
Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin 0.2
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 0.15
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.13
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 0.12
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 0.12
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 0.12
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 0.1
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 0.1
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 0.09
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 0.09
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.08
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.04
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 0.0
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 0.0


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