Gene Query: CDR2L

Dataset Description Geneva Score
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 38.43
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 36.91
Control of prostate tumour growth by the long non-coding RNA GHSROS 31.46
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (mRNA-Seq) 31.32
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 30.15
MOF acetyl transferase regulates transcription and respiration in mitochondria 28.62
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 26.79
Atheroprotective flow alters EZH2/H3K27me3 dependent transcriptional profile in human endothelial cells 26.4
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 26.05
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 23.24
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 23.15
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 22.98
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 22.53
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 20.06
IL-33 activates tumor stroma to promote intestinal polyposis 19.08
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 18.28
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 17.81
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 17.81
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 17.53
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 17.03
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 16.95
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 16.89
snRNAs as regulators of alternative splicing 16.66
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 16.48
Tracking of dCas9-methyltransferase footprints 16.48
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 16.17
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 15.95
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 15.45
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 15.29
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 14.74
Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoids culture 14.19
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 14.09
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 13.99
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 13.7
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 13.69
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 13.48
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 13.43
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 13.43
Lysine benzoylation is a novel histone mark [RNA-seq] 13.4
Lysine benzoylation is a novel histone mark 13.4
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 13.27
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 13.27
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 13.12
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 13.06
Paxillin regulates genomic networks in prostate cancer [C4-2] 12.96
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 12.95
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 12.92
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 12.9
RNA sequencing of GlyH-101-treated MCF-7 cell line 12.49
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 11.53
Global gene expression differences between blood- and lymphatic-specific human dermal microvascular endothelial cells 11.25
BAF controls genome accessibility 11.22
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 11.17
Nutritional control of protein translation 10.96
Paxillin regulates genomic networks in prostate cancer [LNCaP] 10.81
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 10.69
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 10.65
Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure 9.89
A novel non-canonical signaling pathway mediates TGF-β1-induced glucocorticoid insensitivity in epithelial cells 9.88
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 9.84
Effect of nuclear IL-33 on gene expression 9.67
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 9.67
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 9.67
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 9.5
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 9.46
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 9.42
RNAseq of HEK293 cells after Chtop knockdown 9.36
Co-transcriptional loading of RNA export factors shapes the human transcriptome 9.36
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 9.26
METTL3 promotes translation in human cancer cells 9.15
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 9.07
RNA-sequencing analysis of human fibrolamellar hepatocellular carcinoma and 4 maturational stages of the human hepatobiliary system 9.01
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 8.97
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 8.97
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 8.95
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 8.95
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 8.91
RNA-seq of cells with TET1 knockout 8.91
mRNA Sequencing of Human PromoCells Using Random Primed mRNA-Sequencing Technique 8.88
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns 8.86
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 8.83
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 8.71
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 8.7
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 8.7
DECIDUALIZATION INDUCES A SECRETOME SWITCH IN THE PERIVASCULAR NICHE CELLS OF THE HUMAN ENDOMETRIUM 8.67
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 8.62
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 8.62
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 8.15
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 8.15
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 8.14
Rorc disruption in human FG pancreatic cancer cells 8.13
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 8.12
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2) 8.02
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells 8.02
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 7.99
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 7.97
Regulation of highly expressed hCINAP on translatome 7.9
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 7.87
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 7.87
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 7.87
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 7.85
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 7.85
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 7.84
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 7.84
High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues 7.73
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 7.7
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 7.7
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 7.65
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 7.63
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 7.59
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 7.59
Human optic chiasm from healthy controls and multiple sclerosis patients 7.55
Multiple sclerosis and EAE 7.55
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 7.48
CHCHD2 gene KO effect in iPSC drived motor neurons 7.39
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 7.34
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 7.33
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 7.32
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 7.32
Analysis of transcriptional regulation by Myt1 and Myt1l 7.3
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 7.25
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 7.24
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 7.24
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 7.23
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 7.2
Fbxo32 mediated gene expression program underlies EMT and metastasis 7.13
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 7.12
SUV420H2 knockdown in PANC-1 7.01
Region-specific Innate Antiviral Responses of the Human Epididymis 6.99
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq] 6.98
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 6.96
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs 6.95
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs [RNA-seq] 6.95
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 6.86
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 6.86
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 6.86
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 6.8
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 6.77
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 6.74
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 6.72
Transcriptome analysis of virus infected tissues 6.71
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 6.71
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 6.7
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 6.67
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 6.67
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 6.58
Nrf2 regulated genes in A549 cells 6.58
Identification of Nrf2 regulated genes by RNA sequencing 6.58
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 6.57
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 6.54
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 6.49
Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13 6.47
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 6.47
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 6.46
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 6.41
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 6.38
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 6.38
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 6.31
The human blood-nerve barrier transcriptome 6.27
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 6.25
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 6.24
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 6.22
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 6.22
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 6.18
Differentiation enhances Zika virus infection in neuronal brain cells 6.18
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 6.11
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 6.08
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 6.03
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 5.98
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 5.98
Altering cancer transcriptomes using epigenomic inhibitors 5.98
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 5.98
Gene expression changes after LOC550643 silencing 5.87
Gene expression changes due to PARP knockdown in human cells 5.85
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 5.84
High-throughput sequencing of pluripotent cells 5.82
Regulation of hypoxia-inducible factor activity by ZMYND8 5.74
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 5.73
Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues 5.73
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 5.73
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 5.72
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 5.7
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 5.7
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 5.69
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 5.68
Patient-derived organoids (PDOs) model treatment response of metastatic gastrointestinal cancers. 5.67
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 5.63
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 5.57
Allelic expression mapping across cell lineages reveal repressor disruption among disease SNPs 5.51
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 5.5
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 5.5
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 5.49
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 5.45
MYCi361 regulates MYC target genes 5.44
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming 5.4
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 5.39
Gene Expression Profiling of SPOP Knocked Down Cell 5.39
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 5.32
Generation of mature lung alveolar epithelial cells from human pluripotent stem cells 5.31
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 5.29
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 5.28
An integrative analysis of non-coding regulatory DNA variations associated with autism 5.27
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 5.27
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 5.24
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 5.23
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 5.23
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 5.22
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 5.19
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 5.18
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 5.18
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 5.16
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 5.16
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 5.16
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 5.16
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 5.15
Microprocessor mediates transcription termination in long noncoding microRNA genes 5.13
Differetially expressed genes after hTR overexpression in U2OS cells 5.12
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 5.11
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 5.09
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 5.08
Functional role of CPPED1 in trophoblasts. 5.03
Downregulation of DDX5/DDX17 and REST 4.98
RNA-Seq analysis of HIF-2a-responsive genes in clear-cell renal cell carcinoma 4.97
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 4.95
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 4.9
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 4.9
Disruption of the exocyst induces podocyte loss and dysfunction 4.87
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 4.83
MYCi975 regulates MYC target genes 4.83
RNA-Seq of Kaposi’s sarcoma reveal alterations in glucose and lipid metabolism 4.79
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 4.79
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 4.79
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 4.79
HNF1 regulates critical functions of the human epididymis epithelium. [RNA-Seq] 4.77
HNF1 regulates critical functions of the human epididymis epithelium. 4.77
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 4.76
Entrectinib Resistance in a Neuroblastoma Xenograft Model 4.75
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 4.73
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 4.72
Downregulation of LATS kinases alters p53 to promote cell migration 4.7
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 4.68
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 4.66
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 4.64
Arginine citrullination at the C-terminal domain controls RNA Polymerase II transcription 4.64
T47D RNA-seq and ChrRNA-seq data 4.64
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 4.56
Statins modulate endothelial transcriptional profile by inhibiting EZH2 4.56
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 4.54
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 4.54
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 4.53
SETBP1-WT and SETBP1-G870S epigenetic landscapes 4.53
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 4.51
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 4.49
4.47
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 4.45
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 4.45
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 4.43
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 4.4
RNA-seq of SCLC PDX models treated with EP 4.38
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 4.38
ARS2 is a general suppressor of pervasive transcription [RNAseq] 4.37
Gene expression regulated by CSA and CSB in neuroblastoma cell line 4.36
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 4.34
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 4.34
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 4.32
Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted hearts 4.27
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 4.25
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 4.25
A549 cell transcriptome responses to infection with H7N9 influenza virus 4.23
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 4.23
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 4.21
Gene Expression Profiling of WT and KDM3A Knocked out Cell 4.21
Regulation of poly(A) tail and translation during the somatic cell cycle 4.21
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 4.15
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 4.13
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 4.12
ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex 4.04
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 4.02
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 4.0
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 4.0
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 4.0
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation [RNA-Seq] 3.95
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation 3.95
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 3.92
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 3.92
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 3.86
CSL 3.77
CSL RNA-Seq on HKC and SCC cell lines 3.77
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 3.76
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 3.75
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 3.75
Transcriptome profiling of Cryptosporidium parvum infected lung and intestinal organoids 3.74
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 3.67
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1 3.62
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 3.6
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 3.59
Silencing SPIB in attached and floating state of H1703 lung cancer cells 3.56
MRTF activates TEAD-YAP target gene expression 3.54
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 3.54
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 3.5
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 3.48
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 3.45
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 3.45
X-Ray induced DNA-Hydroxymethylation changes 3.45
Polycomb complexes associate with enhancers to promote oncogenic transcriptional programs in cancer 3.43
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 3.37
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 3.37
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 3.35
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 3.35
Molecular analysis of renal cell carcinoma with unclassfied histology 3.34
Molecular analysis of renal cell carcinoma with unclassfied histology [gene expression] 3.34
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 3.34
Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells 3.33
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 3.3
Trnascriptome analysis of HeLa cells infected with rTHOV-wt, -dML, -SW mutant or mock-treated 3.27
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 3.25
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 3.25
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 3.25
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 3.19
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing 3.18
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing [RNA-Seq] 3.18
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 3.17
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 3.17
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 3.14
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 3.14
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 3.12
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 3.12
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 3.09
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 3.08
RNA-seq analysis of control and Myc-induced U2OS cells 3.05
CDK4/6 inhibitor resistance in prostate cancer 3.05
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 3.05
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 3.04
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 3.0
Treatment of prostate cancer cells with S-adenosylmethionine leads to genomewide alterations of transcription profiles 3.0
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 3.0
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 3.0
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 2.94
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 2.87
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 2.86
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 2.81
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 2.75
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 2.72
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 2.69
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 2.64
RNA-seq of cultured human kidney peritubular microvascular endothelial cells following exposure to cyclosporine A 2.62
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 2.62
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 2.62
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 2.61
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 2.6
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 2.59
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 2.59
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 2.55
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 2.51
Effects of transcription on genome - nuclear lamina interactions 2.48
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 2.48
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 2.47
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 2.45
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 2.44
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 2.44
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 2.39
Functional Haploid Human Oocytes Generated from Polar Body Genomes 2.39
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress [human] 2.39
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress 2.39
Transcriptomic analysis of LSD1 2.37
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 2.37
RNA editing in nascent RNA affects pre-mRNA splicing 2.36
Gene expression changes in human melanoma cell lines compared to primary melanocytes 2.34
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 2.27
Gene expression analysis of human liver progenitor-like cells in culture 2.26
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 2.26
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 2.23
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 2.23
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 2.23
RNA-seq analysis upon ARID1B overexpression 2.2
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 2.19
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 2.19
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and SMAD4 Y95 Mutation Transcriptomes 2.15
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 2.12
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 2.12
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 2.12
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 2.12
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 2.07
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 2.04
KLF6-dependent transcription in renal cancer cells 2.01
Redifferentiation of expanded human islet β cells by inhibition of ARX 2.0
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 1.98
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 1.98
The circadian transcriptional landscape in primary human mammary epithelial cells 1.98
RNA-sequencing of healthy human skeletal myocytes 1.93
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells 1.93
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells [RNA-Seq] 1.93
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing 1.92
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 1.9
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.87
Tracing Enhancer Networks using Epigenetic Traits (TENET) 1.86
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 1.82
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 1.79
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 1.75
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 1.74
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 1.74
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.71
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 1.68
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 1.68
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 1.64
Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft] 1.64
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.64
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.64
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 1.57
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 1.55
Subcellular pathways shared by afflicted patients and mutant mice identify a new drug treatment for aortic aneurysm in Marfan syndrome 1.54
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 1.54
Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response 1.53
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 1.5
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.48
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 1.48
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 1.48
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4 1.47
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_TK] 1.45
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 1.43
RNA seq analysis of human Fetal and adult derived Enterospheres 1.41
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 1.39
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 1.33
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 1.32
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 1.27
Mutational landscape of splicing genes and functional consequences across 33 cancer types 1.27
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 1.23
Transcriptomic analysis of ERR alpha orphan nuclear receptor 1.17
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 1.16
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 1.14
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.11
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 1.03
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 1.0
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 1.0
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 0.9
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 0.82
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 0.77
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 0.77
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [RNA-Seq] 0.77
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray 0.77
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 0.77
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 0.77
Investigate A2M treatment on human prostate cancer and mouse liver 0.76
Investigate A2M treatment on human prostate cancer xenograft in mice 0.76
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 0.73
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 0.73
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 0.71
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 0.71
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 0.7
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 0.7
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 0.68
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.68
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 0.67
Transposon-based construction of strand-specific RNA-seq libraries 0.67
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 0.66
RNA-Seq of Breast and Ovarian Cancer Cell Lines 0.65
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 0.65
RNAseq data from Mesenchymal stem cells treated with TCDD or 1-methyl tryptophan 0.64
FOXP2's impact on the primate transcriptome 0.62
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 0.62
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 0.62
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 0.62
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 0.62
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.55
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 0.55
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 0.53
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 0.53
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 0.52
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 0.5
RNA-sequencing in immortalized human mammary epithelial cells 0.5
Alternative splicing regulated by QKI and RBFOX1 promotes the mesenchymal cell state in breast cancer 0.5
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 0.49
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 0.48
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.46
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 0.44
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 0.43
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.37
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.37
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 0.36
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 0.36
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 0.35
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 0.34
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  0.32
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 0.31
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 0.31
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 0.31
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 0.24
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) in proliferation, quiescence, senescence and transformed states. 0.22
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 0.22
Characterizing the Chemoresistant Ovarian Cancer Population using the Heterogeneous PDX 0.22
Genome-wide Analysis of Chromatin Interactions in Human Cells 0.22
Activating Transcription Factor 4 modulated TGFb-induced aggresiveness in triple negative breast cancer vis SMAD2/3/4 and mTORC2 signaling 0.2
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.19
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.19
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.14
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.14
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.11
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.11
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 0.08
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 0.01


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