Gene Query: CHCHD2

Dataset Description Geneva Score
CHCHD2 gene KO effect in iPSC drived motor neurons 97.62
Comparative Transcriptome analysis of hESCs- and iPSCs-derived lentoid body 94.95
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 88.56
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 76.02
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 75.59
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 75.22
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (chromatin-bound RNA-seq) 63.98
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 63.84
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 59.55
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 57.39
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 56.84
Pluripotent stem cell models of Blau syndrome reveal an IFN-<gamma>-dependent inflammatory response in macrophages 54.47
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 54.2
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 52.12
NRDE2 negatively regulates nuclear exosome functions 49.77
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 49.75
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 44.41
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 43.3
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 42.27
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 41.82
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 41.37
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 37.81
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 36.97
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 36.01
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 35.36
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 35.36
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 34.46
Impact on erythroid progenitor type on erythroid differntiation 34.1
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 31.68
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 31.42
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 31.2
HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma associated herpesvirus ORF57 protein and host pre-mRNA metabolism 28.92
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 28.5
Total RNA sequencing of WT intestinal orgaonids. 28.39
Transcriptomic profiling of HeLa cells infected with Salmonella Typhimurium 27.95
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 27.87
LncRNA expression profiling of ischemic stroke patients 27.74
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 27.6
Cellular gene expression during Hepatitis C Virus replication revealed by Ribosome profiling 27.36
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 27.19
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 27.19
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 27.03
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 26.9
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 26.83
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 24.83
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 23.99
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 23.99
An RNA-centric dissection of host complexes controlling flavivirus infection [RNA-Seq] 23.62
An RNA-centric dissection of host complexes controlling flavivirus infection 23.62
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 23.6
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 23.55
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 23.32
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 23.1
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 22.0
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion 21.72
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 21.53
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 21.5
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 20.44
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 20.3
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 20.16
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 20.16
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 20.04
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 19.82
Mitochondrial dsRNA triggers antiviral signalling in humans 19.3
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing 19.17
DJ-1 is dispensable for human stem cell homeostasis 18.83
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 18.75
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 18.41
Next Generation Sequencing of human SMA and healthy control Motor Neurons 18.31
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 18.06
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 18.02
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 17.97
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 17.91
RNA sequencing, chromatin accesibility and ChIP seq analysis of BAP1 -/- human liver organoids 17.85
Gene expression profiling of leukemia cells following asparagine depletion 17.76
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 17.73
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 17.61
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing 17.6
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing [RNA-Seq] 17.6
Global analysis of enhancer targets: Mosaic-seq 17.39
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 17.37
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 17.36
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 17.25
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 17.2
IMP3 regulated gene expression in breast cancer cells 17.16
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 17.1
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 16.99
Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression 16.98
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 16.83
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 16.74
3’ Uridylation Expands miRNA Target Repertoire 16.73
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 16.72
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 16.7
Ribosomal footprinting of CN34-Parental and CN34-LM1a 16.51
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 16.36
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 16.29
Generating Patterned Kidney Organoids for Studying Development and Diseases 16.05
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 15.93
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 15.54
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 15.42
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 15.42
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 15.38
Role of XRN2 ribonucleolytic activity in RNA metabolism 15.36
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 15.3
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 15.27
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 15.08
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 15.08
hnRNP C is a key regulator of protein synthesis in mitosis 15.07
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 15.02
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 15.01
Ribosomal footprinting of MDA-Parental and MDA-LM2 14.91
mRNA expression profile of Lymphocytes 14.88
RNA sequencing of primary human platelets and in vitro cell lines 14.82
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 14.8
The human blood-nerve barrier transcriptome 14.75
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 14.69
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 14.69
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 14.62
RNA-seq of IL-4 stimulated human keratinocytes 14.48
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 14.43
Human embryonic stem cells in E8 and AKIT culture medium 14.43
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 14.39
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 14.39
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 14.08
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 14.08
Targeting EZH2 in MYCN-amplified Neuroblastoma 14.02
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 14.02
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 13.76
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 13.72
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 13.67
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 13.67
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 13.65
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 13.64
Role of microRNAs in the interaction between Salmonella and the host cell 13.61
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 13.6
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 13.38
Identification of transcription start sites for human A549 cell line using ReCappable-seq 13.35
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 13.23
RNA-seq melanoma 13.23
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 13.15
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 13.07
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 13.07
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 13.07
Identification of Atrial Fibrillation associated genes and functional non-coding variants 13.03
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 12.91
Sensing self and nonself circular RNAs 12.84
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 12.84
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 12.77
Subclonal cooperation drives metastasis through modulating local and systemic immune microenvironments 12.65
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 12.59
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 12.54
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 12.48
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 12.31
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 12.29
CROP-Seq in Primary Human T Cells 12.29
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding 12.15
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 12.01
Reassessment of Exosome Composition 12.0
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 11.84
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 11.75
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 11.74
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 11.72
Determining mRNA half-lives on a transcriptome-wide scale 11.71
Total RNA sequencing of APC mutant and wt colonic organoids 11.7
Integrative classification of human coding and non-coding genes based on RNA metabolism profiles 11.69
Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13 11.52
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 11.31
U1 snRNP telescripting regulates size-function stratified human genome 11.26
Single-nucleotide-resolution mapping of HBV promoters using CAGE 11.22
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 11.19
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 11.13
RNA-sequencing of human liver tissue 11.08
RNA-Seq with and without RNase treatment in PCa cell lines 11.05
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 11.04
Comparing gene expression in iPSC derived RPE from control and AMD donors 11.02
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects 10.92
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 10.87
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 10.84
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 10.7
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 10.67
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 10.67
Landscape of H3K4me3 in human CD19 cells 10.62
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 10.58
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 10.58
Human serum and heparin-free platelet lysate as appropriate xeno-free alternatives for production of human MuStem cell batches 10.48
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 10.41
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 10.34
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 10.34
Landscape and variation of RNA secondary structure across the human transcriptome 10.32
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 10.32
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 10.26
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 10.17
Differential expression of genes in AD169-infected MRC5. 10.15
Global analyses of the effect of different cellular contexts on microRNA targeting 10.13
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 10.13
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 10.13
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 10.12
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 10.11
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 10.11
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 10.1
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 10.0
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 10.0
SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample 9.99
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 9.97
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 9.97
Transcription elongation regulates genome 3D structure 9.96
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 9.86
Arginine citrullination at the C-terminal domain controls RNA Polymerase II transcription 9.84
T47D RNA-seq and ChrRNA-seq data 9.84
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 9.81
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 9.8
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 9.74
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 9.72
Postnatal lipids drive hepatocyte maturation 9.68
Expression profiles of the four human major ectodermal lineages 9.67
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 9.65
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples 9.65
Hepatocyte maturation 9.64
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 9.62
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 9.62
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 9.62
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 9.6
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 9.6
iPSC-Derived Cholangiocytes 9.6
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 9.53
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 9.52
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 9.4
Stem and effector CD8 T-cells from human cancers 9.35
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 9.28
Transcriptomic insights into human decidual and peripheral blood CD8 T cells 9.28
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 9.24
mRNA expression data from ESCs derived by polar body transfer reconstructed embryos (PBTESCs) 9.19
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 9.18
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 9.18
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 9.11
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 9.09
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 9.05
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 9.02
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 9.02
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 9.0
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 8.86
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 8.86
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 8.8
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 8.78
RNA-seq of resting and activated CD4+ T cells +-JQ1 8.77
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 8.75
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 8.75
Trans-differentiation of human adult peripheral blood T cells into neurons 8.64
Microprocessor mediates transcription termination in long noncoding microRNA genes 8.6
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 8.58
UV_24h_GRO-Seq 8.56
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 8.56
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 8.54
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 8.51
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 8.38
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 8.28
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 8.28
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 8.18
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation 8.16
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq) 8.16
Studying the selectivity of a small molecule Synucleozid on transcriptome 8.16
Differential responses of human fetal brain neural stem cells to Zika virus infection 8.15
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 8.13
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 8.07
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 8.01
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 8.01
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 7.95
The pause-initiation limit restricts transcription activation in human cells 7.93
RNA-seq analysis of melanoma and carcinoma cells expressing FOXQ1 7.86
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 7.85
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 7.8
Disruption of GRIN2B impairs differentiation in human neurons 7.71
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 7.65
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 7.64
iPSC derived motor neuron cultures from C9ORF72 carriers 7.6
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 7.57
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 7.53
Platelet Transcriptome Profiling in HIV and ABCC4 as a Biomarker of Platelet Activity 7.4
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 7.32
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 7.25
Tracing the temporal-spatial transcriptomic landscapes of the human fetal digestive tract by single cell RNA-seq analysis [adult tissues] 7.14
AMPK signaling for naïve pluripotency [Hs] 7.06
AMPK signaling for naïve pluripotency 7.06
Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs) 7.06
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 7.03
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 7.01
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 7.01
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 6.97
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 6.9
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 6.9
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 6.75
ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle 6.68
Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoids culture 6.68
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 6.67
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 6.67
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 6.64
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 6.63
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 6.62
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 6.61
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 6.61
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 6.56
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 6.51
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 6.49
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 6.49
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 6.48
The effect of insulin on mRNA transcription of human pluripotent stem cells 6.45
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 6.36
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 6.31
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 6.31
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 6.31
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 6.3
RNA editing in nascent RNA affects pre-mRNA splicing 6.26
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 24h] 6.22
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 6.21
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 6.21
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 6.21
METTL3 and WTAP 6.18
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 6.15
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 6.11
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 6.09
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 6.07
Polycomb complexes associate with enhancers to promote oncogenic transcriptional programs in cancer 6.05
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 6.04
Functional Haploid Human Oocytes Generated from Polar Body Genomes 6.04
BCL11B 6.0
Triple vectors expand AAV transfer capacity in the retina 5.95
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001 5.93
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 5.92
Tracking distinct RNA populations using efficient and reversible covalent chemistry 5.89
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 5.74
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 5.72
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 5.71
RNA m5C Methylation in breast cancer using MeRIP-Seq 5.66
Examining serotonergic neuron differentiation from human iPSCs 5.57
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 5.56
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 5.49
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 5.48
Solid phase chemistry to covalently and reversibly capture thiolated RNA 5.46
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 5.45
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 5.41
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 5.38
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 5.35
SERPINA3- a novel keratinocyte differentiation promotor mediates epidermal barrier repair response in psoriatic lesion 5.35
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 5.33
miR941 overexpression experiment 5.32
Activity-dependent transcriptional changes in human neurons 5.26
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 5.24
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 5.22
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 5.13
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 5.13
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 5.06
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 5.06
Human cells contain natural double-stranded RNAs with potential regulatory capacity 5.06
miR-93 Targets in Human Endothelial Cells 5.01
Tracing Enhancer Networks using Epigenetic Traits (TENET) 5.01
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 4.77
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 4.74
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 4.74
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 4.71
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 4.67
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 4.56
A High-Throughput Screen Identifies DYRK inhibitor ID-8 that Stimulates Human Kidney Tubular Proliferation 4.49
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 4.47
Effect of FGF13 depletion on the H460 cell line 4.47
Unique features and clinical importance of acute alloreactive immune responses 4.45
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 4.42
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 4.42
Epigenomic conservation of transposable element silencing [RNA-seq] 4.42
Epigenomic conservation of transposable element silencing 4.42
Transcriptome analysis of kidney organoids 4.4
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 4.35
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 4.28
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 4.16
Differential Protein Occupancy Profiling of the mRNA Transcriptome 4.1
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 3.91
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 3.89
Peptidomimetic blockade of MYB in acute myeloid leukemia 3.89
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 3.86
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 3.8
Molecular Pathology of adverse local tissue reaction caused by metal-on-metal implants 3.8
RNAseq in Alzheimer's Disease patients 3.71
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 3.68
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 3.64
Regulatory network controlling tumor-promoting inflammation in human cancers 3.64
Regulatory network controlling tumor-promoting inflammation in human cancers [RNA-seq] 3.64
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 3.64
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 3.6
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 3.45
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 3.4
Dilated cardiomyopathy vs Myocarditis 3.39
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 3.36
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 3.35
RNA-sequencing of healthy human skeletal myocytes 3.33
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 3.33
Gene expression patterns define the hepatocyte-like cells derived by different strategies 3.26
Gene expression patterns define the hepatocyte-like cells derived by different strategies [RNA-seq] 3.26
Mesothelioma xenografts in nude mice: PBS treated versus pirfenidone treated 3.25
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 3.22
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 3.19
Profiling of escape kinetics of viruses subjected to RNAi 3.17
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 3.15
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 3.13
A single-cell transcriptome atlas of the human pancreas 3.13
Measure transcript integrity using RNA-seq data 3.12
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 3.11
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 3.11
Gene expression profiles of rescue with wild type or SUMO double mutant TRIM24 3.07
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 2.99
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 2.88
MicroRNA-125a-5p overexpression in human macrophages 2.78
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 2.7
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 2.7
4sUDRB-seq: measuring transcription elongation and initiation genomewide 2.53
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 2.44
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 2.41
Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells. 2.4
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 2.39
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 2.39
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 2.35
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 2.32
Transcriptome-wide response to synthetic chromatin protein PcTF 2.23
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 2.18
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 2.16
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 2.16
Transcriptome analysis upon C6orf203 silencing 2.15
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 2.11
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 2.04
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 2.02
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 1.98
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 1.96
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 1.95
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 1.84
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 1.81
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 1.81
Long non-coding RNA expression profile associated with malignant progression of oral submucous fibrosis 1.81
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 1.78
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 1.77
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 1.75
Transcriptome of human ILC2s; primary vs IL-1b-primed 1.74
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 1.73
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 1.71
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 1.71
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 1.7
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 1.7
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 1.7
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 1.56
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 1.5
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 1.5
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 1.47
Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids 1.38
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 1.35
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq 1.22
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.19
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 1.18
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 1.16
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 1.16
Transcriptome profiling of A2M treated A549 Cell Line Samples 1.16
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 1.14
Identification of a LIF-responsive replication-competent human β cell 1.13
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 1.1
Assessing placental maturity through histological and transcriptomic analyses in idiopathic spontaneous preterm birth 1.09
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 1.08
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 1.08
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 0.95
iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension 0.89
RNA-Seq analysis of human colorectal cancer with liver metastasis 0.77
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 0.75
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 0.74
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 0.73
Transcriptional changes during naturally-acquired ZIKA Virus infection render dendritic cells highly conducive to viral replication 0.71
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.71
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 0.69
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 0.69
Wide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling 0.65
Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle 0.63
Transcriptomic Analysis Of circRNAs/miRNAs/mRNAs upon Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection 0.6
Neutrophils RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 0.56
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 0.52
siRNA-mediated knockdown 0.48
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 0.45
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 0.41
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 0.41
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.4
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 0.4
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 0.4
Compare of gene expression between p16INK4A positive and negative regions of colon cancer from five patients 0.34
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 0.33
Enhancer activation during EGF response 0.28
The transcriptomic landscape of MAIT cell development in the thymus (C006 RNAseq data set) 0.18
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 0.18
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 0.16
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 0.12
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 0.12
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.08
Myc activation coordinates gene transcription and protein translation responses 0.07
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.06
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 0.05
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.03
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 0.01
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 0.0


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