Gene Query: CHUK

Dataset Description Geneva Score
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 46.46
R430: A potent inbibitor of DNA and RNA viruses 37.23
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 23.26
Nrf2 regulated genes in A549 cells 21.28
Identification of Nrf2 regulated genes by RNA sequencing 21.28
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 16.62
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 16.5
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 16.01
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 15.86
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 14.66
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 14.54
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 14.28
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 14.28
Human cell line and subcutaneous tumor 14.25
Global gene expression profiling from LeuCAG3'tsRNA depleted- HeLa and HCT-116 cell lines through 50 base pair paired-end RNA-seq 13.99
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 13.95
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 13.91
Effect of PRDM11 depletion in U2932 cells 13.34
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 12.97
3’ Uridylation Expands miRNA Target Repertoire 12.89
LncRNA-GAS5 negative regulation of YAP-target genes expression 12.83
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 12.22
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 11.48
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 11.37
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 11.16
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 11.16
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 10.83
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 10.74
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 10.57
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 10.57
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 10.01
single cell RNA-seq from GM12878 (ENCSR673UIY) 9.95
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 9.9
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 9.87
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 9.84
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 9.78
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 9.51
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 9.43
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 9.39
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 9.2
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 9.11
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 9.1
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 9.01
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 8.96
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 8.77
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 8.63
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 8.61
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 8.61
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 8.58
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 8.47
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 8.47
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 8.41
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 8.4
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 8.23
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 8.23
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 8.18
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 8.18
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 8.09
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 8.05
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 7.98
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 7.86
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 7.84
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 7.72
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 7.67
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 7.61
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 7.59
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 7.59
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 7.52
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 7.5
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 7.41
Hijacking of stress response machinery by oncogenes in acute leukaemia 7.41
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 7.41
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 7.25
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 7.24
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 7.23
Total RNA-seq in ALL-SIL upon TLX1 knockdown 7.2
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 7.18
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 7.18
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 7.17
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 7.13
Cajal bodies are linked to genome conformation 7.12
Cajal bodies are linked to genome conformation [RNA-Seq] 7.12
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 7.1
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 7.08
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 7.07
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 7.07
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 7.01
SLIGRL-induced gene expression changes in NHEK cells 6.99
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 6.92
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 6.85
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_1A_PI3K_RNA-seq] 6.83
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 6.76
Tracking distinct RNA populations using efficient and reversible covalent chemistry 6.7
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 6.69
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 6.57
RNAseq of HEK293 cells after Chtop knockdown 6.56
Co-transcriptional loading of RNA export factors shapes the human transcriptome 6.56
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 6.54
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 6.54
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 6.52
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 6.4
Global analysis of alternative splicing regulated by RBM10 6.4
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 6.39
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 6.38
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 6.36
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 6.35
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 6.32
Transcriptome analysis of BAP1 knockout and restoration 6.31
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 6.31
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 6.27
RNA-seq of resting and activated CD4+ T cells +-JQ1 6.23
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 6.2
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 6.17
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 6.13
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 6.12
Tracking of dCas9-methyltransferase footprints 6.11
RIG-I and MDA5 fRIP during KSHV lytic reactivation 6.04
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 6.02
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 6.02
MOF acetyl transferase regulates transcription and respiration in mitochondria 6.02
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 6.01
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 6.01
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 5.99
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 5.94
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 5.93
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 5.88
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 5.88
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 5.85
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 5.85
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 5.84
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 5.82
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 5.8
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 5.79
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 5.79
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 5.74
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 5.63
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 5.61
Regulation of highly expressed hCINAP on translatome 5.55
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 5.51
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 5.47
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 5.46
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 5.46
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 5.46
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 5.44
MYCL and EP400 are required for Max and MCPyV mediated gene activation 5.43
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 5.39
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 5.38
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 5.38
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 5.36
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 5.32
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 5.27
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 5.26
RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines 5.25
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 5.24
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 5.23
Transcriptomic analysis of LSD1 5.2
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 5.19
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 5.18
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 5.14
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 5.09
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 5.08
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 5.06
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 5.06
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 5.06
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells [RNA-seq] 5.06
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells 5.06
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 4.98
Active translatome profiling with RiboLace in MCF7 cells 4.96
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 4.94
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 4.94
Seletive inhibition of CDK9 in DLBCL cell lines 4.94
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 4.93
Regulation of protein translation during mitosis 4.84
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 4.84
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 4.81
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 4.81
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 4.81
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 4.81
Ribosomal footprinting of CN34-Parental and CN34-LM1a 4.81
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 4.81
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 4.81
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 4.78
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 4.76
Inhibition of TNBC metastasis by Gpx1 4.76
Transcriptome analysis upon C6orf203 silencing 4.7
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 4.69
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 4.65
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 4.65
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 4.64
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 4.64
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 4.6
Integrin signaling regulates YAP/TAZ to control skin homeostasis 4.6
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 4.58
Gene expression changes after LOC550643 silencing 4.57
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 4.55
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 4.54
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 4.5
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 4.49
RNAseq Analysis in glioblastoma cells treated with Mepazine 4.48
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 4.47
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 4.47
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 4.44
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 4.41
Capturing the Interactome of Newly Transcribed RNA 4.4
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.4
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 4.37
Transcriptome landscape of HeLa response upon triamcinolone acetonide 4.37
RNA-seq analysis to identify the genes regulated by p53-SET interplay 4.35
Impact of dieldrin on transcription in Jurkat T cells 4.33
Global Mapping of Human RNA-RNA Interactions 4.32
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 4.3
Silencing p300 in MCF7 cells to study expression and alternative splicing 4.29
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs 4.28
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs [RNA-seq] 4.28
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 4.26
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 4.26
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 4.26
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 4.22
METTL3 and WTAP 4.21
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 4.19
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 4.17
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 4.16
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 4.15
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 4.15
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 4.15
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 4.14
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 4.13
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 4.12
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 4.11
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 4.07
Transcriptome of U251 cells overexpression complement component 7 4.06
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 4.06
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 4.06
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 4.05
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 4.03
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 4.03
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 4.02
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 3.99
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 3.99
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 3.97
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 3.96
RNA-seq analysis of control and Myc-induced U2OS cells 3.91
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 3.89
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 3.88
FBXW7 modulates stress response by post-translational modification of HSF1 3.88
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 3.85
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 3.83
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 3.82
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 3.81
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 3.78
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 3.78
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 3.75
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 3.73
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 3.67
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 3.66
Antibody-Mediated Inhibition of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity 3.64
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 3.63
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 3.6
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 3.58
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 3.56
RNA sequencing analysis of selumetinib-resistant CRC cells lines 3.54
RNA-seq of RKO cells with cTAZ KO or putback 3.4
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 3.4
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 3.4
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 3.37
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 3.37
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 3.36
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 3.36
SETBP1-WT and SETBP1-G870S epigenetic landscapes 3.36
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 3.36
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 3.3
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 3.28
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 3.26
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 3.23
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 3.22
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 3.21
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 3.19
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 3.19
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 3.19
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 3.19
Effect of ILF3 on translation during homeostasis and the antiviral response 3.14
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 3.12
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 3.08
Effect of nuclear IL-33 on gene expression 3.05
Conservative alteration of chromosomal expression pattern across human solid tumor types 3.04
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 3.04
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 3.03
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 3.02
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 2.99
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 2.98
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 2.98
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 2.96
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 2.96
6mer seed toxicity in tumour suppressive microRNAs 2.96
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 2.92
Human cells contain natural double-stranded RNAs with potential regulatory capacity 2.92
Gene expression analysis upon mtDNA depletion [RNA-seq] 2.89
Gene expression analysis upon mtDNA depletion 2.89
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 2.87
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 2.87
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 2.85
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 2.85
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 2.85
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 2.85
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 2.82
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 2.78
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 2.77
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 2.74
Effect of BB608 on Gene Expression in HNSCC Cell Line 2.73
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 2.72
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 2.72
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 2.72
JunB control of keratinocyte-mediated inflammation [RNA-seq] 2.7
RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-kB-dependent inflammation 2.7
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 2.68
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 2.63
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 2.63
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 2.61
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 2.61
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 2.6
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 2.56
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 2.53
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 2.53
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 2.52
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 2.51
N6-methyladenosine (m6A) profiling of EndoC-bH1 cell line and RNA seq of Mettl14 knockout mice beta cell 2.48
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 2.46
Gene expression changes due to PARP knockdown in human cells 2.46
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 2.45
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 2.45
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 2.44
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.42
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 2.4
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 2.4
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 2.34
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 2.32
PRDM1 inhibits proliferation of human colon cancer organoids 2.28
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 2.28
Human Treg IFNg/IL-10 subpopulations 2.26
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 2.25
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 2.19
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 2.18
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 2.18
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.16
Role of COP1 on MAP kinase transcriptional output in melanoma 2.16
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 2.15
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 2.14
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 2.13
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 2.13
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 2.13
Real-time observation of light-controlled transcription in living cells 2.11
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 2.09
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 2.05
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 2.04
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 2.01
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 2.0
RNA-seq of MDA-MB-231 cells with TET1 knockout 1.99
Functional significance of the HIV-1 Tat signature amino acid residues 1.99
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 1.97
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 1.97
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 1.91
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 1.9
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 1.89
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 1.89
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 1.88
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 1.85
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 1.85
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 1.85
EWSR1 influences alternative splicing through direct and indirect mechanisms 1.82
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 1.81
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 1.81
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 1.81
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 1.79
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.77
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 1.74
O-glcnAc reprograms cellular energetics 1.74
Comparative Analysis of Cas9 Activators Across Multiple Species 1.73
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 1.73
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 1.72
A20 regulates canonical wnt-signaling through an interaction with RIPK4 1.69
LIN28A Over-expression RNAseq 1.64
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.61
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 1.6
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 1.58
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 1.57
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 1.57
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 1.48
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 1.43
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 1.4
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 1.39
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 1.39
Transcriptional profiling of LS1034 cells treated with tepoxalin 1.37
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.37
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.37
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 1.35
The contribution of Alu exons to the human proteome 1.35
mRNA expression levels in splenic human mononuclear cells of mock- and HIV-1-infected humanized mice 1.34
Identification of a LIF-responsive replication-competent human β cell 1.27
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 1.27
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 1.25
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 1.25
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 1.22
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 1.22
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 1.17
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 1.16
Transposon-based construction of strand-specific RNA-seq libraries 1.16
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.15
A code of mono-phosphorylation modulates the function of RB. 1.14
Characterization of parental and rociletinib-resistant derived H1975 cell lines 1.12
Gene expression profiling of human iPS cell-derived podocytes and sorted human adult podocytes 1.1
Functional role of CPPED1 in trophoblasts. 1.1
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 1.07
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 1.03
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.02
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.02
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.02
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 1.01
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 0.98
Transcriptional profiling of CD45RO+CD57+CD4+ T cells 0.96
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 0.95
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 0.94
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 0.94
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 0.94
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 0.91
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 0.88
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.87
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 0.87
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  0.86
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.83
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 0.82
Transcriptome-wide modulation of splicing by the exon junction complex 0.8
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 0.79
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 0.79
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 0.78
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.77
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.74
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 0.74
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 0.73
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 0.72
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.71
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 0.71
An siRNA screen identifies CHD4 as a target for epigenetic therapy 0.69
siRNA-mediated knockdown 0.68
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.65
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 0.63
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 0.55
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 0.55
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 0.54
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 0.53
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.53
Expression analysis of genes modulated after knock-down of lncRNA CHROME. 0.53
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 0.51
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 0.49
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 0.49
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) 0.49
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) [RNA-seq] 0.49
Modulation of nonsense-mediated decay by rapamycin 0.47
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 0.46
EZH1/SUZ12 complex positively regulates the transcription of NF-κB target genes via interaction with UXT 0.42
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 0.42
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.41
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.41
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.41
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 0.41
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 0.41
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 0.4
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 0.37
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 0.36
Effects of transcription on genome - nuclear lamina interactions 0.36
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.35
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.35
Transcriptomic analysis of ERR alpha orphan nuclear receptor 0.35
Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection 0.31
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 0.29
6mer seed toxicity in viral microRNAs 0.27
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.24
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 0.23
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.23
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 0.19
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 0.19
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.18
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 0.17
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 0.15
ADAR1-editing of cellular and measles virus-derived duplex RNA 0.15
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.15
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 0.13
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 0.12
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.12
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 0.11
Transcription elongation regulates genome 3D structure 0.08
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 0.07
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.07
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 0.06
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.05
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 0.05
p53 activity results in DNA replication fork processivity 0.03
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.03
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 0.02
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.02
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 0.01


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