Gene Query: CSTF3

Dataset Description Geneva Score
Gene expression analysis of the impact of TDP-43 knockout in human cells. 33.92
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 32.04
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 23.57
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 19.74
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 16.69
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 16.66
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 16.2
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 15.92
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 13.99
Transcription control by the ENL YEATS domain in acute leukemia 13.98
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 13.98
scRNASeq analysis of cycling cardiomyocytes 13.9
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 13.72
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 13.21
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 13.12
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 13.12
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 12.89
EP400 is required for Max and MCPyV mediated gene activation 12.23
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 11.82
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 11.82
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 11.62
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 11.18
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 11.14
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 11.14
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 11.05
Solid phase chemistry to covalently and reversibly capture thiolated RNA 11.02
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 10.99
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 10.93
Differential expression of genes in AD169-infected MRC5. 10.91
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 10.8
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 10.71
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 10.55
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 10.51
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 10.1
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 10.03
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 9.81
Effect of Hotair overexpression in human breast cancer cell lines 9.76
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 9.74
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 9.52
FBXW7 modulates stress response by post-translational modification of HSF1 9.51
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 9.51
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 9.37
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress 9.36
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 9.23
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 9.22
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 9.22
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 9.22
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 9.16
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 8.96
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 8.83
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 8.83
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 8.82
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 8.72
Genome wide expression change by RNF168 knocking down in NEC cells 8.61
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 8.6
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function 8.47
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 8.47
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 8.4
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 8.37
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 8.34
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 8.31
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 8.24
IMP3 regulated gene expression in breast cancer cells 8.01
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 7.93
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 7.91
Effect of FGF13 depletion on the H460 cell line 7.91
RNA sequencing of GlyH-101-treated MCF-7 cell line 7.87
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 7.86
Co-transcriptional loading of RNA export factors shapes the human transcriptome 7.8
RNAseq of HEK293 cells after Chtop knockdown 7.8
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 7.76
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 7.72
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 7.72
Global Mapping of Human RNA-RNA Interactions 7.71
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 7.68
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 7.67
DIGIT regulates endoderm differentiation of human embryonic stem cells 7.56
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 7.5
Maturation of human iNSCs 7.49
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 7.49
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 7.43
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 7.32
Global analysis of enhancer targets: Mosaic-seq 7.28
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 7.28
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 7.28
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 7.2
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 7.18
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 7.15
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 7.13
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 7.08
HNRNPL and its RNA Targets in Prostate Cancer 7.08
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 7.03
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 7.0
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 6.8
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 6.76
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 6.74
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 6.74
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 6.73
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 6.71
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 6.66
MeRIP-seq for heat shock in B-cell lymphoma cells 6.6
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 6.58
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 6.52
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 6.52
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 6.49
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 6.46
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 6.46
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 6.33
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 6.33
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 6.33
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 6.31
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 6.31
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 6.31
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 6.28
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 6.23
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 6.23
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 6.2
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 6.2
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 6.17
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 6.09
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 6.04
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 6.01
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 5.9
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 5.88
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 5.88
Human cell line and subcutaneous tumor 5.88
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 5.87
A549 cells and MSR-A549 cells 5.86
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 5.86
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 5.86
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 5.86
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 5.84
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 5.79
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 5.79
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 5.78
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 5.78
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 5.77
Transcriptomic of MKD (MUC1 kidney disease) patient compares to normal derived kidney epithelial cells 5.77
High-efficiency RNA-based reprogramming of human primary fibroblasts 5.74
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 5.71
Identification of global regulators of T-helper cell lineage specification 5.6
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 5.6
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 5.58
RNA-seq Transcriptome Analysis of AD169 and AD169-ΔUL26 infected MRC5 fibroblasts. 5.57
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 5.54
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 5.52
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 5.48
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 5.47
Total RNA-seq in ALL-SIL upon TLX1 knockdown 5.44
Cellular gene expression during Hepatitis C Virus replication revealed by Ribosome profiling 5.43
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 5.41
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 5.4
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 5.39
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 5.34
Cell responses to dysregulated VZV-induced cell-cell fusion 5.31
RNA expression following TMPRSS11B overexpression or depletion 5.29
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 5.27
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 5.25
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 5.25
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 5.23
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 5.23
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 5.22
LncRNA-GAS5 negative regulation of YAP-target genes expression 5.19
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 5.19
Regulation of protein translation during mitosis 5.16
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 5.13
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 5.12
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 5.11
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 5.11
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 5.06
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 4.97
Patient-derived luminal breast cancer xenografts with progestins 4.97
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling 4.96
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 4.95
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 4.93
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 4.93
Molecular Criteria for Defining the Naive Human Pluripotent State 4.87
LNCaP treated with iBET 4.86
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 4.82
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 4.82
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 4.81
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 4.81
HNF1A deficiency impairs β-cell fate, granule maturation and function 4.78
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 4.77
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 4.77
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 4.77
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 4.74
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 4.73
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 4.73
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 4.71
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 4.71
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 4.7
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 4.7
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 4.67
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 4.67
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 4.67
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 4.65
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 4.64
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 4.64
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 4.64
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 4.63
SLIGRL-induced gene expression changes in NHEK cells 4.63
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 4.62
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 4.6
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 4.6
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 4.58
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 4.55
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 4.54
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 4.54
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 4.5
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 4.48
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 4.45
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 4.42
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 4.41
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 4.41
Generating Patterned Kidney Organoids for Studying Development and Diseases 4.41
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 4.4
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 4.38
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 4.37
IDH3a KO RNA-seq 4.37
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 4.32
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 4.32
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 4.31
Identification of HOXB13 target genes responsive to BET inhibitors 4.31
Effect of PBK knockdown on C4-2 cell transcriptome 4.31
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 4.31
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 4.31
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 4.29
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 4.29
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 4.29
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 4.27
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 4.25
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 4.24
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 4.23
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 4.23
Capturing the Interactome of Newly Transcribed RNA 4.21
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.21
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 4.19
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 4.18
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 4.18
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 4.09
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 4.08
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 4.04
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 4.04
A549 cell transcriptome responses to infection with H7N9 influenza virus 4.03
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 3.99
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 3.99
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 3.92
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 3.92
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 3.9
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 3.89
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 3.88
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 3.87
Single-cell analysis of human kidney organoids 3.87
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 3.85
Transcriptomic analysis of the HOTAIR-regulated genes 3.85
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 3.85
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 3.83
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 3.82
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 3.82
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 3.8
Novel Targeting of Transcription and Metabolism in Glioblastoma 3.79
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 3.78
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 3.75
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 3.73
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 3.73
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 3.67
Genome-wide discovery of human splicing branchpoints 3.65
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 3.64
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 3.62
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 3.6
ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex 3.51
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 3.47
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 3.44
Searching for target genes of miR-508/509/506/514 in HCT116 cells 3.4
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 3.38
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 3.38
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 3.33
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 3.32
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 3.32
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 3.31
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 3.25
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 3.25
Gene expression in GBM with Cav3.2 inhibition 3.21
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 3.21
Functional Haploid Human Oocytes Generated from Polar Body Genomes 3.21
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 3.2
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 3.19
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 3.19
Hepatitis C virus functionally sequesters miR-122 3.16
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 3.16
mRNA differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 3.09
Differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 3.09
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 3.08
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 3.06
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 3.06
Human Treg NaCl stimulation 3.06
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 3.05
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 3.02
Single-cell analysis of adult human ovary using 10X genomics 3.0
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 3.0
Biological effect of chronic mistranslation in mammalian cells 2.95
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 2.94
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 2.93
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 2.93
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 2.9
Human HAP1 cells before and after nutrient deprivation 2.9
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 2.89
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 2.86
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 2.81
Ribosome profiling upon inhibition of eIF4A 2.81
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 2.79
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 2.71
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 2.71
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 2.7
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 2.68
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 2.66
SLAM-seq for K562 endogenous mRNA decay 2.63
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 2.63
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 2.63
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 2.62
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 2.58
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 2.56
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 2.56
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 2.53
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 2.51
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 2.49
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 2.49
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 2.49
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 2.49
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 2.48
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 2.47
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 2.47
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 2.47
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 2.47
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 2.46
Gene expression profile in breast cancer cells 2.46
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 2.45
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.44
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 2.43
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 2.43
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 2.41
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 2.41
Epigenetic reprogramming of melanoma cells by vitamin C treatment 2.4
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  2.38
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 2.38
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 2.34
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 2.27
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 2.27
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 2.25
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 2.23
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 2.21
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 2.19
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 2.18
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 2.18
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 2.18
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 2.13
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 2.13
Functional significance of the HIV-1 Tat signature amino acid residues 2.11
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 2.1
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 2.1
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 2.07
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 2.07
Hypoxic transcriptome of SQ20B human head and neck cancer cells 2.04
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 2.04
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 2.04
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 1.98
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 1.98
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.98
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 1.95
Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy 1.94
Gene expression analysis upon mtDNA depletion [RNA-seq] 1.93
Gene expression analysis upon mtDNA depletion 1.93
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 1.92
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 1.92
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 1.92
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 1.89
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 1.88
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 1.87
Effect of PRDM11 depletion in U2932 cells 1.85
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 1.83
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 1.8
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 1.79
Enhancement of Arterial Specification in Human Pluripotent Stem Cell Cultures Promotes Definitive Hematoendothelial Program with Broad Myelolymphoid Potential 1.78
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 1.77
SRSF1 role in cellular gene expression and splicing 1.76
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 1.75
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 1.72
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 1.69
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 1.68
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 1.67
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 1.62
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 1.61
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 1.6
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.6
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.6
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 1.58
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 1.53
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.49
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.49
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 1.47
Transcriptome-wide modulation of splicing by the exon junction complex 1.45
O-glcnAc reprograms cellular energetics 1.45
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 1.44
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 1.43
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 1.43
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.42
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.38
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 1.37
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 1.37
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 1.36
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 1.33
Profiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis 1.29
NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells 1.27
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 1.26
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 1.22
High-resolution comparative analysis of great ape genomes 1.15
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 1.11
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 1.09
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 1.09
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.08
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 1.07
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 1.06
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.06
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.05
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 1.05
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 1.0
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 0.97
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 0.96
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 0.96
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 0.94
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 0.93
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 0.92
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 0.91
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 0.91
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.91
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 0.89
Novel Non-catalytic Substrate-selective p38α-specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-inflammatory Activity 0.86
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 0.84
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 0.83
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.8
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.77
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 0.76
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 0.74
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 0.74
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 0.73
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 0.73
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 0.73
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 0.7
Function and hormonal regulation of GATA3 in human first trimester placentation 0.7
RNA-seq of MDA-MB-231 cells with TET1 knockout 0.68
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 0.61
SNHG5 siRNA knock down in HCT116 cells 0.6
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 0.59
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 0.59
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.58
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.58
Transcriptional landscape changes during human embryonic stem cell derivation 0.56
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 0.56
MARCKS and lnc-MARCKS act as inflammation regulators 0.56
Next generation sequencing of small RNAs isolated from exosomes in human semen 0.45
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.44
Generation and persistence of human tissue-resident memory T cells in lung transplantation 0.43
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 0.42
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 0.42
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 0.42
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 0.4
Effect of drugs on transcriptomic profiles 0.4
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.37
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.36
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq 0.32
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 0.28
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 0.27
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.24
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.24
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 0.22
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 0.19
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 0.19
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 0.19
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 0.17
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 0.15
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 0.15
Primate-specific gene TMEM14B promotes cortical expansion and folding 0.13
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 0.12
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 0.12
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.12
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 0.1
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 0.1
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 0.09
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 0.09
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.09
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.08
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.06
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.05
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.02
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 0.02
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 0.02
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.01
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.01
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.0


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