Gene Query: CTCF

Dataset Description Geneva Score
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 41.39
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 38.66
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 38.59
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 29.86
Studying the selectivity of a small molecule Synucleozid on transcriptome 28.19
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 27.38
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 23.8
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 22.93
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 22.93
Global gene expression profile of dasatinib-resistant RCH-ACV cells 21.64
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 21.62
Peptidomimetic blockade of MYB in acute myeloid leukemia 20.97
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 20.97
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 19.92
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 18.65
EWSR1 influences alternative splicing through direct and indirect mechanisms 18.56
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 18.3
Effect of FGF13 depletion on the H460 cell line 17.99
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 17.78
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 17.46
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 16.73
Seletive inhibition of CDK9 in DLBCL cell lines 16.5
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 16.16
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 15.39
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 15.19
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 15.16
Effect of drugs on transcriptomic profiles 15.01
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 14.49
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 14.32
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 14.31
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 12.91
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 12.83
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 12.82
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 12.62
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 12.26
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 12.12
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 11.98
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 11.76
RNAseq Analysis in glioblastoma cells treated with Mepazine 11.58
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 11.47
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 11.41
Transcriptome of diurnal human blood neutrophils 11.27
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 11.22
Differentially expressed vascular development genes for iPSC-ECs from CDI 11.19
Tracking of dCas9-methyltransferase footprints 11.18
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 11.0
FBXW7 modulates stress response by post-translational modification of HSF1 10.97
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 10.97
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 10.94
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 10.94
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 10.94
Human Adipocytes Regulate Gene Expression in Triple-negative Breast Cancer Assessed by NGS Sequencing 10.91
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  10.65
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 10.61
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 10.35
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 10.32
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 10.32
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 10.32
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 10.26
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 10.1
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 10.06
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 10.06
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 10.05
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 10.05
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 10.05
Identification of transcription start sites for human A549 cell line using ReCappable-seq 9.99
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 9.96
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 9.77
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 9.73
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 9.54
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 9.54
ETV7 and interferon response 9.4
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 9.4
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 9.37
Transcriptome analysis of Zika infected neural stem cells 9.32
Zika infected neural stem cells 9.32
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 9.23
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 9.19
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 9.18
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 9.18
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 9.12
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 9.11
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 8.99
Resistance to BET inhibitor leads to new therapeutic vulnerabilities in castration resistant prostate cancer 8.98
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 8.97
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 8.95
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 8.89
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 8.83
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 8.83
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 8.8
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 8.77
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 8.76
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 8.74
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 8.63
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 8.62
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 8.55
The evolution of N6-methyladenosine in primates 8.51
Novel Targeting of Transcription and Metabolism in Glioblastoma 8.39
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 8.38
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 8.34
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 8.33
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 8.25
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 8.19
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 8.15
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 8.15
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 8.08
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 8.07
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 8.01
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 7.99
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 7.98
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 7.97
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 7.96
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 7.95
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 7.91
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 7.86
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 7.85
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 7.82
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 7.74
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 7.73
A Unique Epigenomic Landscape Defines Human Erythropoiesis 7.73
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 7.73
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 7.71
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 7.71
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 7.65
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 7.64
TT-Seq captures the human transient transcriptome 7.6
Triple vectors expand AAV transfer capacity in the retina 7.6
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 7.58
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 7.55
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 7.54
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 7.48
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 7.45
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 7.45
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 7.45
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 7.4
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 7.4
hnRNP C is a key regulator of protein synthesis in mitosis 7.3
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 7.28
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 7.28
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 7.26
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 7.23
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 7.22
Comparative Transcriptome analysis of hESCs- and iPSCs-derived lentoid body 7.21
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 7.21
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 7.19
RNA-seq of naive and primed ES cells 7.17
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 7.06
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 7.02
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 7.02
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 6.99
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 6.99
A novel target of EZH1/2 for treatment of mantle cell lymphoma 6.99
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 6.91
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 6.91
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 6.91
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 6.83
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 6.83
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 6.79
CROP-Seq in Primary Human T Cells 6.79
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 6.78
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 6.74
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 6.68
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 6.68
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 6.67
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 6.6
DJ-1 is dispensable for human stem cell homeostasis 6.6
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 6.59
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 6.58
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 6.54
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 6.54
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 6.51
High-throughput sequencing of pluripotent cells 6.5
Platelet Transcriptome Profiling in HIV and ABCC4 as a Biomarker of Platelet Activity 6.46
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 6.45
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 6.45
Disruption of the exocyst induces podocyte loss and dysfunction 6.39
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 6.39
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 6.37
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 6.35
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 6.32
Genes significantly down or Up-regulated upon RNF219 knockdown 6.3
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 6.28
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 6.28
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 6.21
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 6.21
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 6.19
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 6.19
IMP3 regulated gene expression in breast cancer cells 6.18
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 6.17
U1 snRNP telescripting regulates size-function stratified human genome 6.1
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 6.08
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 6.08
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 6.07
Uridylation by TUT4 and TUT7 marks mRNA for degradation 6.06
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 6.04
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 6.04
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 5.99
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 5.97
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 5.95
MYC dependent mRNA translation shapes gene expression and cell biology 5.9
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 5.9
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 5.87
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 5.83
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 5.82
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 (RNA-Seq) 5.81
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 5.81
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 5.75
T47D RNA-seq and ChrRNA-seq data 5.75
Arginine citrullination at the C-terminal domain controls RNA Polymerase II transcription 5.75
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 5.74
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 5.73
Tyrosine Kinase Inhibitor Cardiotoxicity 5.72
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 5.72
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 5.71
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 5.71
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 5.7
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 5.67
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 5.67
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 5.66
LncRNA-GAS5 negative regulation of YAP-target genes expression 5.65
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 5.65
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 5.61
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 5.58
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 5.57
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 5.57
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 5.56
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 5.56
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 5.55
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 5.53
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 5.52
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 5.47
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 5.45
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 5.43
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling 5.4
RNA-seq in transgenic cells 5.39
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 5.39
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 5.38
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 5.35
IRF1 regulates IFN dependent and independent gene expression 5.31
Human embryonic stem cells in E8 and AKIT culture medium 5.21
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 5.21
Targeting MTHFD2 in Acute Myeloid Leukemia 5.21
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 5.2
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 5.1
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 5.07
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 5.01
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 4.99
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 4.98
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 4.97
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 4.83
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 4.79
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 4.79
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 4.77
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 4.76
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 4.76
Intron retention induced by microsatellite expansions as a disease biomarker. 4.72
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 4.7
Human lymph nodes maintain a unique subset of resident memory T cells with high functional potential important for protective immunity and immunotherapies 4.69
Ro60-knockout cells 4.64
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 4.63
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 4.63
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 4.6
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 4.57
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 4.54
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 4.54
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 4.5
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 4.47
Defective structural RNA processing in relapsing-remitting multiple sclerosis 4.46
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 4.45
Searching for target genes of miR-508/509/506/514 in HCT116 cells 4.43
Molecular Criteria for Defining the Naive Human Pluripotent State 4.39
AUF-1 affected genes in human skin cells 4.38
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 4.35
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 4.29
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 4.29
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 4.23
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 4.23
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 4.2
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 4.19
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 4.19
The DPYSL2 gene connects mTOR and schizophrenia 4.18
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 4.17
Copper Regulation of HIF-1 Transcription Activity 4.17
SLIGRL-induced gene expression changes in NHEK cells 4.16
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 4.15
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 4.15
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 4.13
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 4.05
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 4.04
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 4.02
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 4.02
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 4.01
Gene expression profile in breast cancer cells 3.99
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 3.99
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 3.99
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 3.89
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis 3.87
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 3.84
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 3.82
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 3.67
The transcriptome effect of overexpressing EZH2 in MCF7 3.66
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 3.65
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 3.65
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 3.62
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 3.53
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 3.53
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 3.48
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 3.43
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 3.38
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 3.37
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 3.34
Whole blood RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 3.33
In vitro modeling of human germ cell development using pluripotent stem cells 3.31
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 3.3
Human Treg NaCl stimulation 3.25
Mapping interactions for the TNIP2 hub protein 3.24
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 3.21
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 3.16
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 3.16
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 3.15
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 3.12
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 3.11
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 3.11
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 3.06
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 3.03
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 2.98
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 2.98
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 2.98
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 2.96
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 2.96
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 2.94
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 2.88
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 2.84
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 2.8
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 2.8
Effect of SF3B1 suppression in cancer cells with different SF3B1 copy-number levels 2.78
Gene expression profiles of rescue with wild type or SUMO double mutant TRIM24 2.73
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 2.72
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 2.72
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 2.72
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 2.71
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 2.7
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 2.7
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 2.6
Determining mRNA half-lives on a transcriptome-wide scale 2.59
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 2.57
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 2.56
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 2.56
RNA-seq of RKO cells with cTAZ KO or putback 2.56
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 2.56
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 2.56
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 2.55
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 2.53
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 2.44
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 2.42
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 2.42
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 2.41
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 2.38
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 2.33
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 2.33
Integrative classification of human coding and non-coding genes based on RNA metabolism profiles 2.32
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 2.3
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 2.3
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 2.28
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 2.22
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 2.21
Transcriptome-wide modulation of splicing by the exon junction complex 2.16
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 2.16
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 2.15
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 2.12
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 2.12
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 2.11
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 2.1
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 2.08
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 2.05
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 2.02
RNA expression analysis upon JMJD1C depletion 2.02
RNA-seq data 2.0
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 2.0
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 2.0
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 1.99
Expression profiling of MCF-7 cells with treatment of TCDD 1.99
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 1.99
Interaction between mitoNEET and NAF-1 in cancer cells 1.97
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate. 1.96
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 1.95
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 1.95
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 1.94
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 1.93
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 1.92
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 1.88
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 1.84
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 1.83
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 1.83
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 1.81
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 1.8
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 1.8
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 1.79
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 1.77
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 1.77
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 1.76
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 1.76
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 1.67
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 1.66
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 1.64
SNHG5 siRNA knock down in HCT116 cells 1.63
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 1.63
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 1.62
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 1.59
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 1.58
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.57
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 1.54
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 1.54
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 1.51
m6A-dependent regulation of messenger RNA stability 1.47
Function and hormonal regulation of GATA3 in human first trimester placentation 1.47
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 1.46
Generation and persistence of human tissue-resident memory T cells in lung transplantation 1.45
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.43
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 1.4
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 1.39
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 1.37
CDK12 mediated transcriptional regulation in U2OS cells 1.33
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.3
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 1.29
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 1.29
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 1.29
Effect of nuclear IL-33 on gene expression 1.28
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 1.25
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 1.25
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 1.24
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 1.2
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 1.19
naive T cell heterogeneity after neonatal thymectomy 1.18
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 1.14
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 1.13
Transcriptome profiling of A2M treated A549 Cell Line Samples 1.12
Transcriptional landscape changes during human embryonic stem cell derivation 1.11
Gene expression in skeletal muscle in older individuals subject to ten days of complete bed rest. 1.06
HEK293 TFAM Knockout Expression Study 1.05
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 1.0
RNA seq with AML (NB4) cells upon FTO inhibition 0.98
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.96
Modulation of nonsense-mediated decay by rapamycin 0.94
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 0.93
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.92
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 0.91
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.91
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 0.88
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.87
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 0.86
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.86
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 0.78
Iron response of HepG2 cells 0.78
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 0.63
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 0.63
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 0.57
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 0.57
Impact of Escherichia coli K12 and O18 on human platelets: effects on platelet activation, spliced platelet RNAs and proteins 0.54
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.53
UV_24h_GRO-Seq 0.53
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 0.48
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 0.48
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.48
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 0.47
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 0.47
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 0.46
RNA-seq analysis of primary patient samples to characterize the CNS leukemia 0.39
Transcriptome analysis of CNS leukemia 0.39
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 0.38
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 0.36
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.33
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 0.32
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 0.27
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 0.27
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 0.26
Uridylation by TUT4 and TUT7 marks mRNA for degradation [RNA-Seq] 0.25
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.24
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 0.23
Expression analysis of the TAF1 syndrome 0.19
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 0.19
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.18
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 0.17
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 0.16
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.14
Metastasis in triple-negative breast cancer 0.14
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer. 0.14
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.08
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 0.08
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.07
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 0.05
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.04
Gene expression activation in CLL mediated by MSCs contact 0.03
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.03
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.03
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.01
Tracking transcriptional changes in a species-specific manner during experimental hepatoblastoma progression in vivo 0.01
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.01
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.01
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.01


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