Gene Query: CUL1

Dataset Description Geneva Score
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 65.72
Effect of Hotair overexpression in human breast cancer cell lines 51.48
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 28.65
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 26.67
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 20.25
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 20.07
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 19.36
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 19.35
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 18.94
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 18.39
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 17.92
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 17.4
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 17.4
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 17.34
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 17.01
Effects of rFVIIIFc on human macrophages 16.86
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 16.8
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 16.55
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 16.38
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 16.32
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 16.27
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 15.99
Genes significantly down or Up-regulated upon RNF219 knockdown 15.76
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 15.49
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 15.49
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 14.83
Genome wide expression change in LCC2 and MCF-7 cells 14.78
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 14.49
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 14.26
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 13.77
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 13.77
Generation and functional characterization of MDSC-like cells 13.41
AUF-1 affected genes in human skin cells 13.39
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 13.36
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 13.35
Novel Targeting of Transcription and Metabolism in Glioblastoma 13.26
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 13.25
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 13.2
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 12.89
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 12.88
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 12.72
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 12.65
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 12.6
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 12.44
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 12.34
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 12.29
Co-transcriptional loading of RNA export factors shapes the human transcriptome 12.22
RNAseq of HEK293 cells after Chtop knockdown 12.22
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 12.19
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 12.16
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 12.0
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 11.97
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 11.89
3’ Uridylation Expands miRNA Target Repertoire 11.6
Gene expression changes associated with resistance to tagraxofusp (SL-401) 11.28
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 11.26
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 11.11
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 11.05
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 10.99
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 10.8
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 10.75
Transcriptional changes in lymphoma cells induced by LSD1 depletion 10.72
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 10.72
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 10.6
Searching for target genes of miR-508/509/506/514 in HCT116 cells 10.54
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 10.52
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 10.52
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 10.5
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 10.31
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 10.31
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 10.21
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 10.19
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) 10.1
EWSR1 influences alternative splicing through direct and indirect mechanisms 10.03
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 9.93
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 9.93
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 9.86
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 9.74
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 9.71
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 9.68
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 9.65
Sensing self and nonself circular RNAs 9.65
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects 9.63
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 9.61
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 9.6
Genome wide expression change by RNF168 knocking down in NEC cells 9.59
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 9.42
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 9.31
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 9.29
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 9.27
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 9.12
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 9.1
The evolution of N6-methyladenosine in primates 9.1
Global Mapping of Human RNA-RNA Interactions 9.06
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 8.96
MYC dependent mRNA translation shapes gene expression and cell biology 8.95
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 8.94
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 8.9
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 8.78
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 8.78
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 8.77
DHX36 is the missing link to understand RNA G-quadruplex structures, mRNA stability, and translation [RNA-seq] 8.76
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 8.75
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 8.72
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 8.72
Genome-wide discovery of human splicing branchpoints 8.71
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 8.69
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 8.51
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 8.49
Knockdown of ADNP in HCT116 colon cancer cells 8.46
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 8.46
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 8.46
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 8.45
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 8.4
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 8.39
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 8.32
RNA-seq of YB5 cells treated with Proscillaridin A 8.3
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 8.27
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 8.26
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 8.22
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 8.11
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 8.11
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 8.04
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 8.04
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 8.04
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 8.04
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 8.03
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 8.02
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 7.98
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 7.98
Genome-wide discovery of human splicing branchpoints [RNAse] 7.98
Effect of disulfiram treatment on pediatric high grade glioma 7.96
Gene expression analysis of the impact of TDP-43 knockout in human cells. 7.96
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 7.93
Effect of FGF13 depletion on the H460 cell line 7.91
Mapping interactions for the TNIP2 hub protein 7.87
Human Treg NaCl stimulation 7.86
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 7.83
Total RNA-seq in ALL-SIL upon TLX1 knockdown 7.78
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 7.78
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 7.74
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 7.74
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 7.68
Developmental stage specific chromosome architecture in human erythroid cells 7.68
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 7.68
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 7.66
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 7.66
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 7.64
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 7.63
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress 7.6
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 7.58
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 7.58
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 7.58
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 7.48
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 7.44
TCF7L1 knockdown in pancreatic cancer 7.43
Survival of pancreatic cancer cells lacking KRAS function 7.43
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 7.38
LINC00520 is Induced by Src, STAT3, and PI3K and Plays a Functional Role in Breast Cancer 7.37
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 7.34
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 7.33
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 7.32
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 7.28
Transcriptional responses of melanoma cells to BRAF inhibition 7.26
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 7.24
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 7.24
Intrahepatic MAIT cell gene expression revealed by RNA-seq 7.23
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 7.2
Human cells contain natural double-stranded RNAs with potential regulatory capacity 7.16
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 7.14
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 7.14
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 7.14
Ribosomal footprinting of CN34-Parental and CN34-LM1a 7.06
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq] 7.04
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 7.02
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 6.95
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 6.93
FBXW7 modulates stress response by post-translational modification of HSF1 6.92
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 6.92
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 6.91
High-throughput sequencing of PROMPT-enriched samples. 6.83
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 6.77
RIG-I and MDA5 fRIP during KSHV lytic reactivation 6.77
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 6.74
Targeting EZH2 in MYCN-amplified Neuroblastoma 6.7
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 6.7
Nucleoporin-mediated regulation of cell identity genes 6.68
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 6.67
K562 polyA RNA-Seq 6.66
RNA-Seq with and without RNase treatment in PCa cell lines 6.64
Resistance to BET inhibitor leads to new therapeutic vulnerabilities in castration resistant prostate cancer 6.64
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 6.61
Ribosomal footprinting of MDA-Parental and MDA-LM2 6.59
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 6.59
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 6.57
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation 6.56
Transcriptomic insights into human decidual and peripheral blood CD8 T cells 6.51
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 6.51
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 6.51
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 6.5
Seletive inhibition of CDK9 in DLBCL cell lines 6.44
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 6.44
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 6.42
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines (mRNA-Seq) 6.41
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines 6.41
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 6.33
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 6.32
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 6.3
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 6.3
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 6.27
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 6.26
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 6.26
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 6.25
Co-regulation of splicing by Rbfox1 and hnRNP M 6.25
Transcriptome Profiling of Human Primary Monocytes 6.25
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 6.23
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 6.22
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 6.18
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 6.14
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 6.13
PTHrP overexpression in MCF7 cells 6.13
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 6.09
Capturing the Interactome of Newly Transcribed RNA (RICK) 6.07
Capturing the Interactome of Newly Transcribed RNA 6.07
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 6.06
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  6.05
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 6.04
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 6.02
Transcriptome wide analysis of classically and alternatively activated macrophages 5.97
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 5.96
SRSF1 role in cellular gene expression and splicing 5.93
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 5.91
Loss of CREBBP results in gene expression repression in lymphoma cells 5.91
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 5.82
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 5.79
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 5.79
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 5.79
Determination of tRNA aminoacylation levels by high throughput sequencing 5.79
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 5.78
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 5.78
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 5.72
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs [RNA-seq] 5.7
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs 5.7
Trnascriptome analysis of HeLa cells infected with rTHOV-wt, -dML, -SW mutant or mock-treated 5.7
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 5.69
Effect of PBK knockdown on C4-2 cell transcriptome 5.68
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 5.66
RNA-seq analysis of RALD iPSCs after in vitro differentiation 5.64
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 5.61
METTL3 and WTAP 5.6
Human cell line and subcutaneous tumor 5.59
Molecular Criteria for Defining the Naive Human Pluripotent State 5.57
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 5.55
RNA Sequencing of Human iPS derived Cardiomyocytes 5.53
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 5.51
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 5.5
Systematic discovery of endogenous human ribonucleoprotein complexes 5.48
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 5.46
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 5.41
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 5.41
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 5.39
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 5.33
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 5.32
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 5.32
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 5.3
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 5.3
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 5.29
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 5.29
Transcriptome-wide response to synthetic chromatin protein PcTF 5.27
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 5.26
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 5.24
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 5.14
mRNA expression profile of Lymphocytes 5.13
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 5.07
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 5.04
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 5.02
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 4.99
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 4.9
Transcriptome of Stabilin-1 siRNA transfected human monocytes 4.83
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 4.82
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 4.81
The effect of Abl kinases on non-small cell carcinoma global transcriptome 4.73
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 4.73
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 4.72
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 4.72
Zone dependent distinctive gene expression profile of the normal human liver tissue 4.69
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 4.69
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 4.69
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 4.68
SLIGRL-induced gene expression changes in NHEK cells 4.67
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 4.66
RNA-seq of naive and primed ES cells 4.63
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 4.55
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 4.44
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 4.44
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 4.37
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 4.37
Global response to chemotherapy-induced apoptosis 4.37
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 4.34
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 4.31
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 4.29
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 4.28
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 4.28
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 4.26
Transcriptional dependencies in diffuse intrinsic pontine glioma 4.18
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 4.14
Transcriptome of U251 cells overexpression complement component 7 4.14
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 4.13
RNA-seq of naive and primed ES cells (NHSM) 4.09
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 4.07
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 4.05
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 4.04
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 3.91
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 3.9
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 3.9
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 3.87
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 3.87
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 3.86
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 3.83
The cytokine environment influence on human skin-derived T cells 3.83
Transcriptome landscape of HeLa response upon triamcinolone acetonide 3.83
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 3.79
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 3.78
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 3.77
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 3.77
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 3.77
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 3.72
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 3.68
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 3.67
Transcriptomic changes mediated by β-amyloid in human aortic endothelial cells (HAOEC) 3.64
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 3.62
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 3.62
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 3.6
RNA-seq of RKO cells with cTAZ KO or putback 3.6
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 3.6
In vitro modeling of human germ cell development using pluripotent stem cells 3.54
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 3.51
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 3.49
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 3.49
RNA-seq of cultured human kidney peritubular microvascular endothelial cells following exposure to cyclosporine A 3.34
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 3.32
NAPRT activation of macrophages 3.29
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 3.28
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 3.23
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 3.22
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 3.15
Conservative alteration of chromosomal expression pattern across human solid tumor types 3.14
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 3.13
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 3.08
Whole blood RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 3.06
Isolation and Functional Interrogation of Adult Human Prostate Epithelial Stem Cells at Single Cell Resolution 3.05
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 2.99
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 2.91
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 2.91
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 2.9
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 2.86
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 2.82
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 2.74
Comparative Analysis of Cas9 Activators Across Multiple Species 2.69
The Genetic Landscape of Diamond-Blackfan Anemia 2.67
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 2.6
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 2.59
SNHG5 siRNA knock down in HCT116 cells 2.59
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 2.57
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 2.56
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 2.55
Gene expression profile in breast cancer cells 2.55
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 2.55
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 2.53
Human macrophages exhibit high activity to clear intracellular biovar Microtus strain of Y. pestis 2.5
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 2.49
Ribosome profiling upon inhibition of eIF4A 2.47
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 2.41
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 2.38
miR-93 Targets in Human Endothelial Cells 2.38
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 2.35
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 2.29
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 2.27
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 2.24
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 2.19
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 2.16
ADAR1-editing of cellular and measles virus-derived duplex RNA 2.16
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 2.15
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 2.13
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 2.0
Macrophage Ad5f35 PhenoMap 1.97
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.97
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 1.96
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 1.95
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 1.94
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 1.93
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.93
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 1.91
Gene expression regulated by CSA and CSB in neuroblastoma cell line 1.9
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 1.89
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 1.89
Human Treg IFNg/IL-10 subpopulations 1.87
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 1.85
Regulatory network controlling tumor-promoting inflammation in human cancers [RNA-seq] 1.83
Regulatory network controlling tumor-promoting inflammation in human cancers 1.83
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 1.83
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 1.78
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 1.78
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 1.72
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 1.7
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 1.7
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 1.68
RNA seq_PDX2_SHP099 1.68
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 1.65
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 1.62
Aging-associated patterns in the expression of human endogenous retroviruses 1.61
Primate-specific gene TMEM14B promotes cortical expansion and folding 1.57
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 1.57
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 1.55
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 1.55
single cell RNA-seq from GM12878 (ENCSR673UIY) 1.53
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 1.51
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 1.49
Small-molecule targeting of brachyury transcription factor addiction in chordoma 1.49
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 1.45
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 1.43
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 1.4
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 1.4
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.37
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.36
Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile 1.34
Induction of Cardiomyocyte Proliferation [pz-822_human] 1.3
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 1.3
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 1.3
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 1.27
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 1.26
A MYC/GCN2/eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer 1.26
HBEC-shp53-PCHD7 1.25
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.21
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 1.19
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 1.17
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.16
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 1.11
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 1.1
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 1.1
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 1.07
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 1.06
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 [RNA-Seq] 1.06
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 1.05
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 1.04
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 1.01
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 1.01
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.99
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 0.95
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 0.94
RNA sequencing with KSHV infection and enrichment for circular RNAs 0.93
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.93
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.93
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.93
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.89
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 0.86
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 0.84
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 0.84
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 0.83
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 0.72
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 0.68
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 0.65
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 0.64
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 0.64
Solid phase chemistry to covalently and reversibly capture thiolated RNA 0.61
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.59
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 0.55
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 0.49
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 0.48
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 0.48
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.47
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.47
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 0.43
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.4
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.35
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.32
Human Treg IL-12 stimulation 0.32
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 0.29
Modulation of nonsense-mediated decay by rapamycin 0.28
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.27
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.26
Gene expression changes due to PARP knockdown in human cells 0.24
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 0.22
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 0.22
Transcriptional changes during naturally-acquired ZIKA Virus infection render dendritic cells highly conducive to viral replication 0.21
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 0.2
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 0.2
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.18
An siRNA screen identifies CHD4 as a target for epigenetic therapy 0.15
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.14
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 0.13
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.11
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 0.1
Transcriptomic analysis of human macrophages in 3D 0.08
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.05
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.04
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 0.04
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.04
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 0.03
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.0


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