Gene Query: CWC15

Dataset Description Geneva Score
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 69.45
49.28
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4 45.08
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 39.48
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 33.83
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 32.0
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 19.77
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 19.77
Knockdown of ADNP in HCT116 colon cancer cells 18.85
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 18.34
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 17.96
Unique features and clinical importance of acute alloreactive immune responses 17.8
Peptidomimetic blockade of MYB in acute myeloid leukemia 15.91
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 15.91
Rorc disruption in human FG pancreatic cancer cells 15.03
KLF6-dependent transcription in renal cancer cells 14.37
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 13.01
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 12.96
Gene expression analysis of the impact of TDP-43 knockout in human cells. 12.92
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [RNA-Seq] 12.66
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression 12.66
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 12.6
MOF acetyl transferase regulates transcription and respiration in mitochondria 12.53
Large-scale profiling of intracellular signalling pathway activation reveals major distinctions between airway smooth muscle cells of asthmatics and non-asthmatics. 12.28
Identification of transcription start sites for human A549 cell line using ReCappable-seq 11.78
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 11.78
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 11.43
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 11.39
Role for citron kinase in prostate cancer growth 11.37
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 11.32
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 11.25
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 11.07
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 11.07
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 11.03
Genome-wide functional assessment of enhancer activities in the human genome 10.91
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 10.85
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 10.78
Global analysis of enhancer targets: Mosaic-seq 10.66
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 10.65
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 10.64
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 10.47
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 10.44
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 10.44
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 10.42
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 10.42
Transcription elongation factors are in vivo-specific cancer dependencies in glioma 10.2
RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma 10.2
Gene expression in PANC1 cells treated with Rakicidin 10.12
CROP-Seq in Primary Human T Cells 10.1
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 9.92
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 9.89
DART-seq: an antibody-free method for global m6A detection 9.86
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 9.81
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 9.79
HNF1A deficiency impairs β-cell fate, granule maturation and function 9.72
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 9.6
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 9.56
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 8.9
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 8.65
Human cell line and subcutaneous tumor 8.59
Transcriptional profiling of microglia; current state of the art and future perspectives 8.52
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 8.49
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 8.31
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 8.31
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 8.26
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 8.14
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 8.14
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 8.13
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 8.09
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 8.03
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 7.84
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 7.73
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 7.64
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes 7.56
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 7.56
Mapping interactions for the TNIP2 hub protein 7.49
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 7.48
An integrative analysis of non-coding regulatory DNA variations associated with autism 7.41
Expression by CD133+ cells isolated from the adult human exocrine pancreas 7.4
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 7.27
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 7.22
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 7.19
Global expression profiles in cardiac progenitor cells generated by ISX-9 7.19
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 7.19
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 7.13
Regulation of protein translation during mitosis 7.1
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 7.07
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 7.05
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 7.05
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 6.9
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 6.88
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 6.74
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 6.73
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 6.73
Generating Patterned Kidney Organoids for Studying Development and Diseases 6.67
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 6.65
Systematic discovery of endogenous human ribonucleoprotein complexes 6.61
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 6.6
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 6.6
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 6.59
Identification of renal resident macrophages across species 6.51
U1 snRNP telescripting regulates size-function stratified human genome 6.51
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 6.46
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 6.46
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 6.41
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 6.4
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 6.39
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 6.33
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 6.31
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 6.31
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 6.31
RNA sequencing based comparative analysis of human hepatic progenitor cells and their niche from alcoholic steatohepatitis livers 6.3
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 6.24
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 6.23
RNAseq of HEK293 cells after Chtop knockdown 6.22
Co-transcriptional loading of RNA export factors shapes the human transcriptome 6.22
RNA-seq analyisis of PUM2 knockout cells 6.2
The evolution of N6-methyladenosine in primates 6.19
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 6.18
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 6.16
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 6.1
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 6.08
RNA-sequencing of healthy human skeletal myocytes 6.01
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 6.0
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects 5.96
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 5.89
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 5.89
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 5.86
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 5.86
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 5.82
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 5.81
Gene expression changes associated with resistance to tagraxofusp (SL-401) 5.8
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 5.79
Disruption of the exocyst induces podocyte loss and dysfunction 5.74
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 5.69
RNA-Seq with and without RNase treatment in PCa cell lines 5.68
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 5.67
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 5.66
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 5.65
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 5.65
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 5.6
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 5.6
Gene expression changes caused by KRAS in MCF-10A 5.57
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 5.55
Integrin signaling regulates YAP/TAZ to control skin homeostasis 5.5
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 5.49
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 5.48
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 5.48
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 5.43
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 5.43
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 5.39
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 5.35
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 5.3
HEK293 Heat-shock experiment 5.25
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 5.23
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 5.22
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 5.17
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 5.14
RNAseq Analysis in glioblastoma cells treated with Mepazine 5.12
Genes significantly down or Up-regulated upon RNF219 knockdown 5.1
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 5.06
hTERT promotes cell adhesion and migration independent of telomerase activity 5.02
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 5.01
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 4.91
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 4.91
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 4.85
Global gene expression profiling from LeuCAG3'tsRNA depleted- HeLa and HCT-116 cell lines through 50 base pair paired-end RNA-seq 4.84
mRNA expression profile of Lymphocytes 4.81
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 4.79
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 4.78
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 4.77
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 4.74
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 4.73
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 4.67
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 4.66
SUV420H2 knockdown in PANC-1 4.64
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 4.64
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 4.63
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 4.58
LNCaP treated with iBET 4.49
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 4.48
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 4.48
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 4.44
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 4.43
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 4.4
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 4.35
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells 4.32
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells [RNA-seq] 4.32
Tracing transcriptome profiles of human oocyte cultured by growth hormone or not in vitro by single cell RNA-seq 4.29
Hijacking of stress response machinery by oncogenes in acute leukaemia 4.25
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 4.25
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 4.24
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 4.19
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 4.18
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 4.18
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 4.15
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 4.14
LIN28A Over-expression RNAseq 4.11
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 4.11
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 4.04
Enhancement of Arterial Specification in Human Pluripotent Stem Cell Cultures Promotes Definitive Hematoendothelial Program with Broad Myelolymphoid Potential 4.03
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 4.0
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 3.95
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 3.94
Exogenous rescue of KLHL9 in SF210 cell line 3.93
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 3.93
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 3.93
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 3.91
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 3.86
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 3.83
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 3.83
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 3.82
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 3.82
Transcriptomic analyssis following EHMT1/2 inhibition 3.82
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 3.79
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 3.79
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 3.77
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 3.69
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 3.65
Comprehensive comparative analysis of 5’ end RNA sequencing methods 3.61
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 3.6
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 3.59
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 3.59
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 3.59
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation 3.57
Loss of the Chr16p11.2 candidate gene QPRT leads to aberrant neuronal differentiation 3.55
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 3.53
Effect of PBK knockdown on C4-2 cell transcriptome 3.48
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 3.48
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 3.48
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 3.48
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 3.46
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 3.46
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 3.45
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 3.45
Total RNA-seq in ALL-SIL upon TLX1 knockdown 3.44
Primate transcript and protein expression levels evolve under compensatory selection pressures 3.43
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 3.43
Effect of CHKA knockdown on C4-2 cell transcriptome 3.42
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 3.42
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 3.38
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 3.35
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 3.34
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 3.34
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 3.29
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 3.27
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 3.22
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 3.21
TGF-β regulation of miRNA expression in pancreatic cancer 3.2
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 3.19
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 3.19
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 3.15
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 3.15
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 3.15
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 3.14
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 3.14
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 3.13
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 3.07
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 3.04
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 3.04
CDK4/6 inhibitor resistance in prostate cancer 3.03
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 3.02
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 3.01
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 3.01
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 3.01
Global Mapping of Human RNA-RNA Interactions 3.0
High-throughput sequencing of PROMPT-enriched samples. 3.0
miRNAs affected by antagomiR-17 treatment 2.92
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 2.9
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 2.89
Gene expression analysis upon mtDNA depletion 2.87
Gene expression analysis upon mtDNA depletion [RNA-seq] 2.87
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 2.86
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 2.86
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 2.86
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 2.84
ETV7 and interferon response 2.84
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 2.78
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 2.76
Transcriptome landscape of HeLa response upon triamcinolone acetonide 2.76
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 2.75
Single-cell analysis of human kidney organoids 2.73
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 2.73
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 2.72
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 2.69
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 2.69
Transcriptome sequencing of K-562 cells 2.66
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 2.66
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 2.65
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 2.65
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 2.61
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 2.6
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 2.58
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 [RNA-Seq] 2.58
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 2.57
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 2.57
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 2.57
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 2.53
Single-cell analysis of adult human ovary using 10X genomics 2.53
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 2.51
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 2.49
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 2.48
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 2.47
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 2.43
RNA sequencing of mechanically strained NHEKs and control NHEKs 2.43
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 2.42
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 2.4
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 2.4
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 2.38
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 2.37
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 2.37
Effect of BB608 on Gene Expression in HNSCC Cell Line 2.32
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 2.31
Transcriptome of human ILC2s; primary vs IL-1b-primed 2.31
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 2.31
Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy 2.23
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 2.23
Next generation sequencing of small RNAs isolated from exosomes in human semen 2.22
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 2.2
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 2.2
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 2.19
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 2.19
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 2.19
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 2.18
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 2.18
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 2.18
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 2.17
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic co-culture 2.17
Ribosome profiling upon inhibition of eIF4A 2.16
In vitro modeling of human germ cell development using pluripotent stem cells 2.13
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 2.13
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 2.13
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 2.13
Functional significance of the HIV-1 Tat signature amino acid residues 2.06
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 2.04
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 2.04
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 2.03
RNA editing in nascent RNA affects pre-mRNA splicing 2.03
Efficient derivation of microglia-like cells from human pluripotent stem cells 2.02
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.01
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 1.98
Expression profiling of etoposide-induced senescent cells 1.97
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 1.94
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 1.94
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 1.93
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 1.93
Molecular Pathology of adverse local tissue reaction caused by metal-on-metal implants 1.92
SRSF1 role in cellular gene expression and splicing 1.92
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 1.9
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 1.9
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 1.9
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 1.88
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 1.85
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.82
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 1.81
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 1.81
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 1.77
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 1.77
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 1.76
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.73
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.73
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 1.73
H1609088 Human RNA-Sequencing 1.71
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 1.69
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 1.67
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 1.66
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 1.66
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 1.66
Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation 1.66
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 1.65
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 1.65
RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq] 1.65
Transcriptomic analysis of ERR alpha orphan nuclear receptor 1.59
Tracking transcriptional changes in a species-specific manner during experimental hepatoblastoma progression in vivo 1.58
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 1.57
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.55
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 1.53
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 1.5
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 1.48
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 1.47
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 1.46
MAIT cell RNA sequencing 1.45
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 1.41
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 1.4
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 1.4
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 1.4
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 1.4
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 1.39
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 1.38
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.37
Integrated epigenomic and transcriptomic profiling of terminal human erythropoiesis [TMCC2] 1.36
Widespread regulated alternative splicing of single codons accelerates proteome evolution 1.34
The cohesin complex prevents Myc-induced replication stress 1.34
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 1.31
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 1.31
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.29
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 1.25
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 1.25
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 1.25
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 1.25
mRNA sequencing of highly and lowly metastatic human colorectal cancer PDXs 1.24
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 1.23
Tracing the temporal-spatial transcriptomic landscapes of the human fetal digestive tract by single cell RNA-seq analysis [adult tissues] 1.23
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 1.22
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 1.12
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 1.11
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 1.11
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 1.11
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 1.1
Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms 1.1
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.05
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.05
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 1.04
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 1.02
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 0.99
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 0.93
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 0.92
Transcriptional landscape changes during human embryonic stem cell derivation 0.91
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.89
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.87
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.87
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 0.87
RNA-Seq of the corpus callosum from 12 individuals 0.86
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 0.83
MicroRNA-125a-5p overexpression in human macrophages 0.82
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 0.82
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 0.82
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 0.82
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 0.82
Profiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis 0.79
Gene expression profiling of papillary thyroid cancer from central and invasive regions 0.75
RNA-seq analysis of Retinoic Acid and Non-treated Control hiPSCs 0.75
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.73
RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer 0.71
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 0.71
HEK293 TFAM Knockout Expression Study 0.69
TOP2B disturbed the quality of human oocytes with advanced maternal age 0.68
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.67
Intrinsic Plasma Cell Differentiation Defects in BENTA Patient B cells 0.63
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.61
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 0.61
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 0.61
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 0.6
Human cells contain natural double-stranded RNAs with potential regulatory capacity 0.6
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 0.59
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 0.59
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 0.59
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 0.58
GATA2 promotes hematopoietic development and represses cardiac differentiation of human mesoderm 0.58
Unraveling cis-regulatory elements by mapping structural changes in mRNAs 0.57
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 0.57
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 0.57
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 0.57
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.55
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 0.55
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.54
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 0.54
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.48
mRNA Sequencing of Human PromoCells Using 3'-directed Digital Gene Expression (3'-DGE) Technique 0.48
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and converts them into tumorigenic cells 0.48
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [BAV] 0.47
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 0.46
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 0.45
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 0.44
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.44
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.43
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 0.41
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing 0.37
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 0.35
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 0.33
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 0.32
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 0.3
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 0.3
Treatment of prostate cancer cells with S-adenosylmethionine leads to genomewide alterations of transcription profiles 0.3
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.29
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.28
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 0.26
miR-93 Targets in Human Endothelial Cells 0.25
Low H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 0.23
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.23
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 0.22
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 0.22
Gene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing. 0.21
siRNA-mediated knockdown 0.21
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 0.2
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 0.17
Activating Transcription Factor 4 modulated TGFb-induced aggresiveness in triple negative breast cancer vis SMAD2/3/4 and mTORC2 signaling 0.17
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.15
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.15
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.14
Transcriptome-wide modulation of splicing by the exon junction complex 0.14
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 0.1
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 0.1
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 0.1
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.09
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.07
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [TAV] 0.05
Dermal endothelial cells of type 2 diabetic patients 0.04
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 0.04
mRNA recovered upon RNF219 IP. [RNA-IP] 0.0


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