Gene Query: DDX54

Dataset Description Geneva Score
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 132.78
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 47.77
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 33.92
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 33.92
Cleavage Factor Im as a key regulator of 3’ UTR length 30.33
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 28.42
Impact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST 27.64
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 24.87
Peptidomimetic blockade of MYB in acute myeloid leukemia 24.87
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 23.35
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 23.35
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 21.76
Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2 21.27
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 19.93
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 18.49
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 17.99
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 17.2
Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells 17.1
Total RNA-seq in ALL-SIL upon JQ1 inhibition 17.09
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 16.98
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 16.95
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 16.61
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 16.61
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 16.39
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 15.63
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 15.63
Differential gene expression of human melanoma cells [RNA-seq] 15.5
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 15.5
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 15.36
Role of XRN2 ribonucleolytic activity in RNA metabolism 15.36
RNA-seq of YB5 cells treated with Proscillaridin A 15.22
miR941 overexpression experiment 15.14
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 15.12
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 15.0
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 14.79
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 14.46
SNHG5 siRNA knock down in HCT116 cells 14.46
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 14.05
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 (RNA-Seq) 13.89
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 13.89
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 13.73
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 13.72
Genome wide expression change by RNF168 knocking down in NEC cells 13.65
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing 13.47
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 13.29
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 13.29
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 13.26
Electronic cigarettes 13.15
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 13.13
Hijacking of stress response machinery by oncogenes in acute leukaemia 12.97
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 12.97
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 12.88
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 12.87
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 12.87
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 12.78
U1 snRNP telescripting regulates size-function stratified human genome 12.71
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 12.67
Developmental stage specific chromosome architecture in human erythroid cells 12.67
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 12.66
Genome wide miR-191 target profile determined by RIP and gene expression profiling 12.66
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 12.65
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 12.59
Effect of FGF13 depletion on the H460 cell line 12.58
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 12.5
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 12.4
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 12.36
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 12.35
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 12.32
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 12.23
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 12.18
DART-seq: an antibody-free method for global m6A detection 12.16
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 12.05
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 12.04
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 12.02
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 12.02
Illumina Total RNA-seq in HeLa 12.01
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 11.95
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 11.95
Inhibition of TNBC metastasis by Gpx1 11.67
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 11.63
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 11.53
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 11.53
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 11.53
High-throughput sequencing of pluripotent cells 11.41
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 11.39
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 11.39
Analysis of transcriptional regulation by Myt1 and Myt1l 11.34
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 11.27
A549 cells and MSR-A549 cells 11.23
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 11.23
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 11.21
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1 11.02
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 11.01
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 11.01
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 10.97
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 10.97
Transcriptome analysis in Neobractatin treated cells 10.91
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 10.81
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 10.81
Genome-wide functional assessment of enhancer activities in the human genome 10.78
Hepatitis C virus functionally sequesters miR-122 10.76
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 10.76
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 10.65
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 10.64
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 10.59
TT-Seq captures the human transient transcriptome 10.57
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 10.51
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 10.5
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 10.48
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 10.41
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 10.38
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 10.22
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq] 10.21
RNA splicing alteration on glioblastoma and normal neural stem cells 10.18
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 10.15
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 10.14
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 10.05
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 9.97
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 9.96
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 9.95
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 9.95
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 9.88
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 9.87
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 9.87
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 9.86
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 9.86
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 9.85
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 9.81
MOF acetyl transferase regulates transcription and respiration in mitochondria 9.76
G-quadruplex structures mark human regulatory chromatin 9.71
RNA-seq and ChIP-seq analysis of BMI1 or RING1B-silenced prostate cancer cells C4-2 9.53
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 9.51
The landscape of alternative splicing in aggressive prostate cancers 9.49
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 9.48
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 9.45
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 9.4
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 9.4
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns 9.36
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 9.35
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 9.33
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 9.3
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 9.3
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 9.29
Global expression profiles in cardiac progenitor cells generated by ISX-9 9.28
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 9.28
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 9.23
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 9.2
Mitochondrial dsRNA triggers antiviral signalling in humans 9.19
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 9.18
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 9.18
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 9.14
Sensing self and nonself circular RNAs 9.1
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 9.08
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 9.08
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 9.0
Identification of HOXB13 target genes responsive to BET inhibitors 8.96
Dtx3L and Androgen Signaling in Prostate Cancer 8.92
Global gene expression profile of dasatinib-resistant RCH-ACV cells 8.9
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 8.88
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 8.82
RNA-seq analysis of RALD iPSCs after in vitro differentiation 8.8
IDH3a KO RNA-seq 8.75
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 8.74
Searching for target genes of miR-508/509/506/514 in HCT116 cells 8.68
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 8.61
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 8.61
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 8.6
Expression profiling of MCF-7 cells with treatment of TCDD 8.6
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 8.57
RNA-seq analysis of differentiating human erythroblasts 8.47
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 8.46
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 8.45
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 8.45
Landscape and variation of RNA secondary structure across the human transcriptome 8.41
Systematic discovery of endogenous human ribonucleoprotein complexes 8.39
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 8.38
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 8.38
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites (RNA-seq) 8.38
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites 8.38
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 8.29
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 8.28
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 8.27
Transcriptome analysis of H9 hESC derived cerebral organoids 8.25
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 8.21
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 8.21
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 8.2
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 8.18
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 8.18
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 8.11
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 8.11
The role of FAM46C in myeloma cells [sequencing] 8.1
The role of FAM46C in myeloma cells 8.1
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 8.1
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 8.07
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 8.04
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 8.01
The evolution of N6-methyladenosine in primates 7.93
Co-regulation of splicing by Rbfox1 and hnRNP M 7.91
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 7.91
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 7.87
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 7.84
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 7.81
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 7.75
Transcriptomic profiling of HeLa cells infected with Salmonella Typhimurium 7.75
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 7.7
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 7.7
MYC dependent mRNA translation shapes gene expression and cell biology 7.69
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 7.68
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 7.68
Reassessment of Exosome Composition 7.6
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 7.58
Paxillin regulates genomic networks in prostate cancer [LNCaP] 7.55
Identification of Sin3B regulated genes during quiescence 7.55
Regulation of poly(A) tail and translation during the somatic cell cycle 7.55
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 7.53
The DPYSL2 gene connects mTOR and schizophrenia 7.52
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 7.51
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 7.48
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 7.46
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 7.41
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 7.41
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 7.33
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 7.32
Combined Genome and Transcriptome Sequencing to Identify Allelic Selection in Epithelial Ovarian Cancer 7.25
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 7.23
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 7.18
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 7.17
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 7.17
Gene expression profiling of leukemia cells following asparagine depletion 7.16
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 7.15
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 7.11
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 7.1
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 7.07
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 7.05
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 7.02
ADAR1-editing of cellular and measles virus-derived duplex RNA 7.02
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 7.01
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 7.0
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 7.0
Global analyses of the effect of different cellular contexts on microRNA targeting 6.99
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 6.99
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 6.98
RNA transcriptome analysis during HSV-1 infection 6.97
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 6.96
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 6.96
SRSF1 role in cellular gene expression and splicing 6.88
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 6.85
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 6.79
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 6.77
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 6.77
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 6.71
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 6.66
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 6.64
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 6.62
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 6.6
The NFkB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells 6.6
Genome-wide analysis of the Integrator complex (HTS) 6.58
Genome-wide analysis of the Integrator complex 6.58
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 6.56
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 6.56
Human cells contain natural double-stranded RNAs with potential regulatory capacity 6.55
Expression data from miR340 overexpressing human A549 cells 6.48
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 6.43
The pause-initiation limit restricts transcription activation in human cells 6.41
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 6.38
Downregulation of DDX5/DDX17 and REST 6.3
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 6.3
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 6.27
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 6.26
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 6.22
Studying the selectivity of a small molecule Synucleozid on transcriptome 6.21
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 6.2
Tracking transcriptional changes in a species-specific manner during experimental hepatoblastoma progression in vivo 6.17
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 6.14
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 6.11
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 6.09
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 6.05
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 6.05
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 5.95
A map of gene expression in neutrophil-like cell lines 5.95
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding 5.9
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 5.89
Functional role of CPPED1 in trophoblasts. 5.84
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 5.79
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 5.68
Mutational landscape of splicing genes and functional consequences across 33 cancer types 5.66
RNA seq with AML (NB4) cells upon FTO inhibition 5.59
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 5.55
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 5.48
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 5.46
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 5.46
DAOY-Notch1/Notch2 knockout: transcriptome comparison 5.45
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 5.43
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 5.37
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 5.37
METTL3 and WTAP 5.35
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 5.35
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 5.33
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 5.32
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 5.32
Iron response of HepG2 cells 5.3
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 5.29
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 5.29
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 5.28
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 5.28
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 5.26
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 5.25
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq] 5.2
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 5.17
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 5.14
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 5.14
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 5.08
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 5.01
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 4.97
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 4.86
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 4.84
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 4.82
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 4.82
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 4.81
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 4.74
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 4.74
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 4.74
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 4.72
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 4.72
RNA-seq of Human neck of femur (NOF) fracture hip and osteoarthritic (OA) cartilage 4.72
Long noncoding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells 4.72
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 4.67
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 4.67
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 4.66
Ectoderm specification of H1 human embryonic stem cells 4.6
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 4.48
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 4.47
Exploring ILF2 regulatory genes by next-generation sequencing 4.45
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 4.44
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 4.39
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 4.38
Ebola virus (EBOV) infection of ARPE-19 cells 4.35
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 4.3
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 4.3
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 4.27
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 4.27
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 4.2
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 4.17
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 4.13
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 4.11
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 4.11
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 4.09
RNAseq Study in CC-671 Treated Cal-51 Cells 4.02
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 4.01
Transcriptome analysis upon C6orf203 silencing 3.86
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 3.83
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 3.83
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 3.82
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 3.81
Multi-omic measurements of heterogeneity in HeLa cells across laboratories 3.76
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 3.69
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 3.63
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 3.63
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 3.59
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 3.59
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 3.57
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 3.57
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 3.56
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 3.56
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 3.52
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 3.52
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 3.52
Downregulation of LATS kinases alters p53 to promote cell migration 3.48
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 3.48
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 3.43
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 3.4
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 3.37
Metastasis in triple-negative breast cancer 3.31
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer. 3.31
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 3.28
Gene expression profile in breast cancer cells 3.28
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 3.26
Tracking distinct RNA populations using efficient and reversible covalent chemistry 3.24
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 3.22
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 3.15
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 2.99
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 2.97
Aneuploidy-induced cellular stresses limit autophagic degradation. 2.9
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 2.86
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 2.86
RNA-seq analysis upon ARID1B overexpression 2.83
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 2.83
RNA-seq of RKO cells with cTAZ KO or putback 2.82
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 2.76
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 2.76
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 2.75
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 2.75
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 2.74
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 2.73
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 2.68
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 2.64
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 2.63
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 2.63
6mer seed toxicity in viral microRNAs 2.61
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 2.6
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 2.6
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 2.54
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 2.53
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 2.35
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 2.33
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 2.31
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 2.31
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 2.31
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 2.29
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 2.26
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 2.23
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 2.23
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 2.22
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 2.17
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 2.16
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 2.04
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 2.01
Profiling of escape kinetics of viruses subjected to RNAi 2.01
Global transcriptome analysis of WT versus HEB-/- hESCs 2.01
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 1.99
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 1.83
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 1.74
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 1.73
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 1.7
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 1.67
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 1.66
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 1.66
SLAM-seq for K562 endogenous mRNA decay 1.61
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 1.58
NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression 1.57
Widespread regulated alternative splicing of single codons accelerates proteome evolution 1.55
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 1.52
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 1.51
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 1.5
Anti-inflammatory effect of indoleacrylic acid (IA) 1.47
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 1.36
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 1.36
MARS Seq data from human cortical organoids 1.35
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 1.34
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 1.31
RNA-seq of MDA-MB-231 cells with TET1 knockout 1.3
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 1.29
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 1.28
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 1.24
The pioneer factor CEBPA modulates vitamin D signaling 1.22
Effects of transcription factor CEBPA knockdown on vitamin D target gene regulation in THP-1 cells 1.22
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 1.18
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 1.18
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 1.09
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 1.09
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.08
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 1.05
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 1.03
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 1.03
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 1.02
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 1.01
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 1.01
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 0.97
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.95
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.95
Transposon-based construction of strand-specific RNA-seq libraries 0.8
The bromodomain protein BRD4 regulates splicing during heat shock 0.8
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 0.77
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 0.77
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 0.77
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.73
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 0.72
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.7
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.7
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.69
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 0.67
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 0.66
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.66
Transcriptomic Analysis Of circRNAs/miRNAs/mRNAs upon Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection 0.61
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 0.59
Transcriptome profiling of A2M treated A549 Cell Line Samples 0.55
Comparative Analysis of Cas9 Activators Across Multiple Species 0.48
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 0.44
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 0.42
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 0.37
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 0.37
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.35
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 0.34
HEK293 TFAM Knockout Expression Study 0.34
RNA-seq differential expression studies: more sequence, or more replication? 0.32
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.31
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 0.29
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.25
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 0.23
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 0.23
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.21
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.19
ChIP-seq and RNA-seq from human lymphoma cell lines 0.19
RNA-seq data from human lymphoma cell lines 0.19
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) in proliferation, quiescence, senescence and transformed states. 0.15
Enhancer activation during EGF response 0.11
Myc activation coordinates gene transcription and protein translation responses 0.09
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.09
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.03
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.03


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