Gene Query: DEF8

Dataset Description Geneva Score
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 75.92
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 38.5
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 38.33
Global gene expression profile of dasatinib-resistant RCH-ACV cells 35.22
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 33.53
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 33.53
Genome-wide MAF1-dependent regulation of RNA polymerase III transcription 33.0
Genome-wide MAF1-dependent regulation of RNA polymerase III transcription [RNA-Seq] 33.0
Characterization of parental and rociletinib-resistant derived H1975 cell lines 23.85
Transcriptional profiles of normal human mature B cells 23.78
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  23.16
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 21.09
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 20.26
Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs) 20.09
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 18.05
Tpl-2 and MEK small molecule inhibitors 18.03
Tpl-2 small molecule project 18.03
RNA-Seq study of Cell lines rendered resistant to idelalisib and ibrutinib 17.23
Widespread intronic polyadenylation diversifies immune cell transcriptomes 16.86
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 16.56
Paxillin regulates genomic networks in prostate cancer [LNCaP] 15.92
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 15.9
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 15.77
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 15.68
Comprehensive comparative analysis of 5’ end RNA sequencing methods 15.38
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 15.11
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 14.95
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 13.45
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 12.87
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 12.74
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 12.69
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 12.69
Clinker: visualizing fusion genes detected in RNA-seq data 12.35
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 12.29
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 12.29
RNA-seq analysis of AML cells in response to ASLAN003 12.07
Landscape of H3K4me3 in human CD19 cells 11.59
Crizotinib v. DMSO in SW480 cells 11.43
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 11.38
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 11.2
Bone marrow derived human B cells [normal proB] 11.18
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 11.08
Human Adipocytes Regulate Gene Expression in Triple-negative Breast Cancer Assessed by NGS Sequencing 10.81
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 10.35
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 10.31
ZIKV infection of monocytes activates inflammasome pathways 10.2
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 10.11
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 9.95
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 9.46
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 9.41
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 9.37
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 9.3
Global analysis of enhancer targets: Mosaic-seq 9.3
RNA-seq analysis to identify the genes regulated by p53-SET interplay 9.28
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 9.27
RNA-sequencing of bulk CD19+ Thymic B cells from mice and humans 9.19
RNA-sequencing of bulk CD19+ Thymic B cells from young (3 month - 4 year) and old (42 - 61 years) humans 9.19
The evolution of N6-methyladenosine in primates 9.08
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 9.06
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 9.06
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 9.02
Hepatitis C virus functionally sequesters miR-122 9.02
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 8.95
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 8.95
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 8.94
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 8.93
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 8.93
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 8.77
The comparison of high-throughput single-cell RNA-seq methods 8.76
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 8.7
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 8.7
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 8.69
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 8.63
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 8.63
SUV420H2 knockdown in PANC-1 8.6
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 8.55
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 8.27
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 8.16
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 8.12
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 8.12
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 8.07
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 8.07
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 7.96
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 7.87
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 7.78
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with Eralpha 7.73
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 7.6
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 7.57
Identification of ZEB1-regulated gene expression changes in HCC827 human lung adenocarcinoma cells 7.55
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 7.47
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 7.43
Transcriptomes change differerntly in differernt cancer cells upon EPZ-6438 treatment 7.35
miR941 overexpression experiment 7.33
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 7.33
Transcriptomes of human monocytes and monocyte-derived macrophages with or without glucocorticoid treatment 7.3
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 7.29
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 7.29
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 7.23
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 7.19
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 7.17
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 7.14
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 7.05
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 7.05
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 6.96
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 6.96
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 6.93
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 6.86
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 6.73
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 6.7
Intron retention induced by microsatellite expansions as a disease biomarker. 6.68
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 6.68
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 6.68
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 6.63
Human Treg IL-12 stimulation 6.59
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 6.59
Co-regulation of splicing by Rbfox1 and hnRNP M 6.55
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 6.55
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 6.5
circRNA-sequencing 6.47
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 6.44
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 6.44
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 6.42
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 6.42
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 6.42
scRNASeq analysis of cycling cardiomyocytes 6.32
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 6.29
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 6.27
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 6.27
BACH2 in human plasma cell fate decision 6.27
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 6.24
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 6.21
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 6.19
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 6.11
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 5.99
Transcriptional profiling of microglia; current state of the art and future perspectives 5.84
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 5.79
Expression analysis of genes modulated after knock-down of lncRNA CHROME. 5.79
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 5.74
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 5.74
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 5.74
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 5.71
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 5.69
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 5.69
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 5.65
RNA-seq analyisis of PUM2 knockout cells 5.64
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 5.63
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 5.6
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 5.59
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 5.57
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 5.56
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 5.56
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 5.55
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 5.48
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 5.47
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 5.47
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 5.39
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 5.37
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 5.34
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 5.31
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 5.3
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 5.25
PTHrP overexpression in MCF7 cells 5.24
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 5.22
Identification of transcription start sites for human A549 cell line using ReCappable-seq 5.16
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 5.16
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 5.16
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 5.11
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 5.1
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 5.06
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 5.06
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 5.03
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 5.03
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 4.99
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 4.95
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 4.91
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 4.91
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 4.9
High-throughput sequencing of pluripotent cells 4.89
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 4.87
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 4.83
CircRNAome diversity in human mature B-cells, T-cells and monocytes 4.8
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 4.79
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 4.79
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 4.78
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 4.77
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 4.77
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 4.7
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 4.69
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 4.69
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 4.66
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 4.66
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 4.65
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 4.65
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 4.63
NAPRT activation of macrophages 4.63
Effect of from Human Umbilical Vein Endothelial Cells 4.62
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 4.57
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 4.56
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 4.55
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 4.53
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 4.53
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 4.52
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 4.51
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 4.5
Transcription control by the ENL YEATS domain in acute leukemia 4.5
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 4.47
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 4.47
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 4.45
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 4.45
Single-cell RNA-seq reveals novel cell differentiation dynamics during human airway epithelium regeneration 4.44
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 4.44
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 4.42
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 4.31
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 4.31
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 4.3
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 4.3
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 4.26
Loss of CREBBP results in gene expression repression in lymphoma cells 4.23
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 4.23
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 4.21
Positively selected enhancer elements endow tumor cells with metastatic competence 4.15
Characterization of Human Pegivirus Infection in Liver Transplantation Recipients 4.11
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 4.06
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 4.0
Searching for target genes of miR-508/509/506/514 in HCT116 cells 3.92
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 3.91
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 3.91
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 3.91
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 3.82
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 3.82
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 3.82
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 3.8
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 3.79
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 3.79
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 3.78
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 3.76
Transcriptomes of human monocytes after ex vivo exposure to uric acid 3.76
Gene expression in GBM with Cav3.2 inhibition 3.76
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  3.76
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 3.73
X-Ray induced DNA-Hydroxymethylation changes 3.72
Effects of rFVIIIFc on human macrophages 3.69
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 3.62
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 3.62
Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure 3.6
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 3.57
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 3.56
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 3.56
PRDM1 inhibits proliferation of human colon cancer organoids 3.54
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 3.49
Endothelial gene expression analysis 3.49
Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation 3.48
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 3.41
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 3.41
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 3.38
A549 cell transcriptome responses to infection with H7N9 influenza virus 3.37
An optimization system for isolating and sequencing of single human colon cancer cells 3.35
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 3.35
Trascriptome of thyroid cancer-induced macrophages 3.33
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 3.3
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 3.3
Global Mapping of Human RNA-RNA Interactions 3.27
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 3.26
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 3.24
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 3.22
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 3.19
Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection 3.14
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 3.13
Total RNA-Seq data from leukemic patients with complex structural variants 3.1
Intrinsic histone acetyltransferase activity of BRD4 is responsible for nucleosome eviction and transcriptional activation 3.1
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq] 3.08
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 3.03
RNA-seq differential expression studies: more sequence, or more replication? 3.02
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 3.0
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 3.0
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 3.0
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 3.0
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 2.95
RNA-seq of RKO cells with cTAZ KO or putback 2.92
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 2.83
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 2.83
Ebola virus (EBOV) infection of ARPE-19 cells 2.82
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 2.78
Gene expression analysis upon mtDNA depletion 2.78
Gene expression analysis upon mtDNA depletion [RNA-seq] 2.78
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes 2.73
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [RNA-seq] 2.73
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 2.71
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 2.68
quanTIseq: quantifying immune contexture of human tumors 2.63
A single cell reference map for human blood and tissue T cell activation 2.61
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 2.6
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 2.59
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 2.59
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 2.59
Transcriptomic analysis of LSD1 2.54
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 2.47
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 2.46
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 2.45
Transcriptomic changes mediated by β-amyloid in human aortic endothelial cells (HAOEC) 2.44
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 2.44
RNA editing in nascent RNA affects pre-mRNA splicing 2.43
Gene expression changes due to PARP knockdown in human cells 2.42
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 2.41
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 2.4
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 2.4
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 2.4
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 2.39
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 2.38
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.37
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways 2.28
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 2.27
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 2.26
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 2.26
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 2.25
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 2.24
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 2.24
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 2.23
Macrophage Ad5f35 PhenoMap 2.2
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 2.19
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 2.17
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 2.17
EZH1/SUZ12 complex positively regulates the transcription of NF-κB target genes via interaction with UXT 2.16
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 2.15
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 2.11
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 2.05
Gene expression analysis of breast cancer cell-lines 2.04
Gene expression and genome-wide location analysis of breast cancer cell-lines 2.04
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 2.04
Dysregulated immune system networks in war veterans with PTSD 2.0
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 1.99
Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells. 1.99
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 1.98
Gene Expression Profiling of WT and KDM3A Knocked out Cell 1.97
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 1.97
miRNAs affected by antagomiR-17 treatment 1.96
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 1.95
A map of gene expression in neutrophil-like cell lines 1.95
Real-time observation of light-controlled transcription in living cells 1.95
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 1.95
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 1.93
Gene expression profile in breast cancer cells 1.93
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 1.89
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 1.89
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 1.86
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 1.8
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 1.8
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 1.8
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 1.8
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 1.75
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 1.75
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 1.75
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 1.71
Illumina Total RNA-seq in HeLa 1.69
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 1.68
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 1.63
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.62
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 1.61
RNAseq of cell lines with knocked in ESR1 mutations 1.61
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 1.61
Transcriptome of Stabilin-1 siRNA transfected human monocytes 1.57
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 1.56
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 1.54
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 1.54
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 1.53
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 1.5
RNA-seq study reveals unique transcriptome expression in systemic lupus erythematosus patients with distinct autoantibody profile 1.5
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 1.48
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 1.47
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 1.47
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 1.45
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 1.43
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 1.42
Triple vectors expand AAV transfer capacity in the retina 1.41
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 1.41
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 1.41
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 1.39
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 1.39
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 1.38
Be1 and Be2 B cells are transcriptionally distinct 1.38
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.38
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 1.37
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 1.37
Effects of plasticizers (bisphenol A, bisphenol AF) and an herbicide in MCF7 human breast cancer cells 1.37
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 1.36
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 1.36
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 1.35
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 1.34
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 1.34
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 1.34
CD74 role in transcription regulation 1.33
CD74 role in transcription regulation [RNA-seq] 1.33
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 1.31
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 1.3
TT-Seq captures the human transient transcriptome 1.3
Transcriptomic analysis of ERR alpha orphan nuclear receptor 1.3
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 1.28
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 1.28
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 1.25
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 1.25
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 1.23
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 1.23
Effect of ILF3 on translation during homeostasis and the antiviral response 1.22
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 1.2
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 1.2
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 1.19
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 1.18
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 1.18
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 1.15
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 1.15
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 1.11
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 1.1
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_TK] 1.09
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 1.09
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 1.09
Interaction between mitoNEET and NAF-1 in cancer cells 1.06
Transcriptome wide analysis of classically and alternatively activated macrophages 1.05
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 1.04
Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection 1.04
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 1.03
Transcriptome analysis of peripheral blood monocytes 1.0
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 0.98
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 0.97
BASP1 modifies the Tamoxifen response 0.95
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.94
Generation and functional characterization of MDSC-like cells 0.92
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 0.92
Energy Metabolism during Anchorage-Independence 0.9
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 0.9
Functional significance of the HIV-1 Tat signature amino acid residues 0.89
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 0.88
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 0.83
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 0.81
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes 0.79
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 0.78
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 0.76
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 0.76
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 0.74
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 0.72
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 0.69
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 0.69
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 0.64
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 0.64
Parallel T-cell cloning and deep sequencing of the transcripts of human MAIT cells reveal stable oligoclonal TCRβ repertoire 0.62
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 0.61
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 0.6
Transcriptomic analysis of human coronary artery endothelial cells stimulated with TNF-alpha in the presence and absence of ACSL3 siRNA 0.6
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.6
LncRNA expression profiling of ischemic stroke patients 0.59
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 0.55
H1609088 Human RNA-Sequencing 0.53
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 0.51
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.5
Treatment of prostate cancer cells with S-adenosylmethionine leads to genomewide alterations of transcription profiles 0.5
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 0.49
Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles 0.43
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 0.4
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 0.4
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in Chronic Lymphocytic Leukemia 0.39
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.39
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 0.38
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 0.38
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 0.36
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.35
Expression profiling of converted and control dermal BJ fibroblasts 0.35
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 0.35
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 0.34
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 0.34
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 0.33
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.32
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.32
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 0.31
Primate transcript and protein expression levels evolve under compensatory selection pressures 0.28
Gene expression activation in CLL mediated by MSCs contact 0.27
Single Cell RNASeq profiling of stromal vascular fraction from Subcutaneous and visceral adipose tissue 0.27
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 0.26
Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy 0.24
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 0.22
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 0.22
Downregulation of LATS kinases alters p53 to promote cell migration 0.21
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 0.21
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 0.2
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 0.19
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 0.18
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 0.17
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 0.15
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.14
Polarized B -cell functions 0.12
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.11
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.1
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 0.1
FBXW7 modulates stress response by post-translational modification of HSF1 0.1
The role of m6A/m-RNA methylation in stress response regulation 0.1
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.1
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 0.07
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 0.07
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 0.07
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 0.06
p53 activity results in DNA replication fork processivity 0.06
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 0.05


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