Gene Query: DLD

Dataset Description Geneva Score
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 46.24
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 39.31
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 30.34
MeRIP-seq for heat shock in B-cell lymphoma cells 27.53
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 27.4
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 26.14
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 26.14
Unique features and clinical importance of acute alloreactive immune responses 24.9
Human cell line and subcutaneous tumor 24.55
Next Generation Sequencing Facilitates Quantitative Analysis of ALDH+ E-BCSC, CD24-CD44+ M-BCSC and Bulk tumor cell Transcriptomes from MC1 and Vari068 PDX models of TNBC 24.11
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 23.51
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 23.51
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 23.36
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 23.36
HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma associated herpesvirus ORF57 protein and host pre-mRNA metabolism 22.87
RNA-seq of YB5 cells treated with Proscillaridin A 22.26
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 21.83
Cleavage Factor Im as a key regulator of 3’ UTR length 21.81
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 21.77
RNA-Seq with and without RNase treatment in PCa cell lines 21.42
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 20.99
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2) 20.85
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 19.65
Determination of tRNA aminoacylation levels by high throughput sequencing 18.76
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 18.12
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 17.79
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 17.52
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 17.52
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 16.93
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 16.78
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 16.35
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 16.35
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 16.08
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 16.08
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects 15.97
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 15.55
Cellular gene expression during Hepatitis C Virus replication revealed by Ribosome profiling 14.78
Effect of Influenza virus infection on lncRNA expression in A549 cells 14.75
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 14.53
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 14.28
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 14.16
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 14.16
Crizotinib v. DMSO in SW480 cells 13.78
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 13.62
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 13.6
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 13.43
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 13.32
Treatment of SW480 colon cancer cell induced xenografts with AZD and DBZ 13.09
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 13.07
Lipid degradation promotes prostate cancer cell survival 13.0
Human embryonic stem cells in E8 and AKIT culture medium 12.97
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 12.97
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 12.94
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 12.52
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 12.5
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 12.5
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 12.5
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 12.44
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation 12.21
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 12.14
Tracking of dCas9-methyltransferase footprints 12.11
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 11.81
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 11.57
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 11.45
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 11.42
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 11.39
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) 11.3
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 11.25
Genome-wide discovery of human splicing branchpoints [RNAse] 11.16
RNA-seq melanoma 11.06
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 11.02
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 11.02
A transcriptome-wide divergence in protein translation scales with LIN28B expression 10.91
Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin 10.89
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 10.87
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 10.83
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 10.81
MYCi361 regulates MYC target genes 10.67
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 10.6
Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13 10.54
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 10.52
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 10.51
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 10.48
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 10.48
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 10.38
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 10.38
Genome-wide discovery of human splicing branchpoints 10.33
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 10.31
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 10.18
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 10.14
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 10.11
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 10.11
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 10.08
mRNA expression profile of Lymphocytes 10.02
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 9.98
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 9.95
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 9.94
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (chromatin-bound RNA-seq) 9.9
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 9.89
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 9.89
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 9.84
Regulation of highly expressed hCINAP on translatome 9.8
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 9.72
Knockdown of ADNP in HCT116 colon cancer cells 9.69
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 9.57
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 9.55
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 9.53
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 9.52
BAF controls genome accessibility 9.49
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 9.47
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 9.47
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 9.45
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 9.43
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 9.43
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 9.43
3’ Uridylation Expands miRNA Target Repertoire 9.39
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 9.38
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 9.38
MicroRNA-125a-5p overexpression in human macrophages 9.37
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 9.36
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 9.35
RNA-seq analysis of A498 cell line treated with siSETD2 or si-NC 9.34
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress 9.32
Transcriptome analysis upon C6orf203 silencing 9.31
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 9.29
Global Mapping of Human RNA-RNA Interactions 9.27
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 9.24
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 9.16
Genes significantly down or Up-regulated upon RNF219 knockdown 9.15
Integrative classification of human coding and non-coding genes based on RNA metabolism profiles 9.13
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 9.13
RNA-seq of resting and activated CD4+ T cells +-JQ1 9.1
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 9.07
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 9.07
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 9.07
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 9.04
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 9.01
Neurofibroma 8.93
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 8.93
MOF acetyl transferase regulates transcription and respiration in mitochondria 8.92
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 8.84
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 8.83
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 8.76
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 8.76
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 8.71
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 8.71
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 8.68
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 8.68
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 8.65
Next generation sequencing of small RNAs isolated from exosomes in human semen 8.61
METTL3 promotes translation in human cancer cells 8.6
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 8.59
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 8.54
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 8.52
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 8.51
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 8.51
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 8.47
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 8.47
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 8.43
The comparison of high-throughput single-cell RNA-seq methods 8.42
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 8.39
Short and Long RNA sequencing of human mature erythrocytes 8.39
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 8.33
PNET animal model: new insights (II) 8.31
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 8.31
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 8.31
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 8.28
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 8.27
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 8.26
RNA sequencing of primary human platelets and in vitro cell lines 8.25
Novel Targeting of Transcription and Metabolism in Glioblastoma 8.18
Identifying the molecular mode of action of itraconazole in colorectal cancer 8.18
Effect of PRDM11 depletion in U2932 cells 8.18
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 8.17
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 8.16
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 8.07
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 8.07
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 8.05
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 8.05
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 8.03
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 8.03
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 8.03
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 8.02
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 7.98
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 7.96
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 7.87
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 7.85
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 7.8
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 7.77
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 7.74
Gene expression analysis of immortalized human liver progenitor-like cells in culture 7.73
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 7.72
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 7.68
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 7.64
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 7.63
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 7.6
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 7.6
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 7.59
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 7.57
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 7.54
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 7.54
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 7.54
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 7.53
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 7.41
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 7.39
Expression level comparison under dividing and quiescent states in human primary fibroblasts 7.35
Transcriptome profiling of CXCR2+ neuroendocrine (NE) tumor cells purified from patients' fresh prostate adenocarcinoma 7.3
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 7.29
Survival of pancreatic cancer cells lacking KRAS function 7.24
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 7.21
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 7.19
m6A-dependent regulation of messenger RNA stability 7.19
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 7.17
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 7.16
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 7.16
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells 7.15
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 7.15
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 7.02
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 7.01
RNA-seq of RKO cells with cTAZ KO or putback 6.99
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 6.98
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 6.96
Patient-derived xenograft platform for metastatic melanoma 6.94
Hepatocyte maturation 6.93
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 6.9
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 6.9
Gene expression in GBM with Cav3.2 inhibition 6.89
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq] 6.84
Mapping interactions for the TNIP2 hub protein 6.82
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 6.73
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines 6.72
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines (mRNA-Seq) 6.72
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 6.71
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 6.7
Effect of ILF3 on translation during homeostasis and the antiviral response 6.62
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 6.59
Transcriptomic analysis of the HOTAIR-regulated genes 6.53
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 6.49
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 6.47
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 6.47
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 6.42
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 6.42
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 6.42
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 6.37
Single-cell analysis of adult human ovary using 10X genomics 6.33
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 6.27
A sister of NANOG regulates genes expressed in pre-implantation human development 6.26
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 6.23
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 6.15
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 6.11
An acquired vulnerability of drug resistant melanoma with therapeutic potential 5.96
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 5.96
Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs) 5.88
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 5.87
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 5.87
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 5.87
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 5.87
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis 5.86
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 5.79
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 5.77
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 5.77
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 5.74
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 5.61
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 5.61
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  5.61
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 5.6
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 5.58
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 5.55
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells 5.53
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 5.49
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 5.48
Transcriptional responses of melanoma cells to BRAF inhibition 5.43
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 5.43
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 5.3
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 5.29
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 5.28
The transcriptome and chromatin accessbility landscape of mammalian germline 5.27
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 5.25
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 5.2
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 5.19
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 5.16
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 5.16
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 5.15
SLAM-seq for K562 endogenous mRNA decay 5.04
Transcriptome landscape of HeLa response upon triamcinolone acetonide 4.94
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia 4.93
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 4.88
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 4.85
Molecular Criteria for Defining the Naive Human Pluripotent State 4.84
Solid phase chemistry to covalently and reversibly capture thiolated RNA 4.83
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 4.76
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 4.76
Gene expression profile in breast cancer cells 4.76
HEK293 Heat-shock experiment 4.73
Primary Human B-cell Temporal Response to CD40L Stimulation 4.73
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 4.73
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 4.72
RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) 4.69
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 4.67
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 4.62
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 4.6
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 4.57
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 4.56
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 4.55
mRNA expression in human DAOY cells 4.54
PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells 4.46
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 4.42
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 4.38
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 4.37
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 4.36
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 4.35
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 4.33
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 4.33
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 4.33
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 4.32
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 4.32
Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein, IFITM3 4.22
mRNA Sequencing of Human PromoCells Using 3'-directed Digital Gene Expression (3'-DGE) Technique 4.21
RNA-Seq of PRMT1 overexpression ECA109 cells 4.17
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 4.12
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 4.11
RNA-seq analysis of SLIRP knockdown with 1nM DHT in LNCaP cells 4.09
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 4.07
RNA-seq of shEZH2 cells 4.07
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 4.01
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 3.93
SRSF1 role in cellular gene expression and splicing 3.85
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 3.84
EZH1/SUZ12 complex positively regulates the transcription of NF-κB target genes via interaction with UXT 3.84
Differential Protein Occupancy Profiling of the mRNA Transcriptome 3.76
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 3.74
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  3.72
Exogenous rescue of KLHL9 in SF210 cell line 3.71
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 3.71
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 3.63
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 3.62
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 3.61
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 3.58
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 3.57
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 3.53
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 3.53
Transcriptome-wide modulation of splicing by the exon junction complex 3.5
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 3.47
Identification of renal resident macrophages across species [C1] 3.45
Transcriptome of U251 cells overexpression complement component 7 3.38
Transcriptome profiling of 5 human adenocarcinoma cell lines 3.35
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 3.31
Human T-cell lymphoblastic lymphoma samples and control thymuses 3.31
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 3.3
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 3.2
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 3.2
Ribosome profiling upon inhibition of eIF4A 3.2
Identification of renal resident macrophages across species 3.12
MARCKS and lnc-MARCKS act as inflammation regulators 3.11
RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer 3.1
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 3.1
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 3.07
The Genetic Landscape of Diamond-Blackfan Anemia 3.04
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 3.03
ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq) 2.97
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 2.95
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 2.95
Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells 2.93
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 2.9
The contribution of Alu exons to the human proteome 2.89
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 2.78
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 2.78
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 2.74
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 2.71
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 2.68
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 2.68
The transcriptome effect of overexpressing EZH2 in MCF7 2.68
Exploring ILF2 regulatory genes by next-generation sequencing 2.67
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 2.63
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 2.63
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 2.49
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 2.48
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 2.48
A549 cell transcriptome responses to infection with H7N9 influenza virus 2.45
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 2.4
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 2.38
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 2.36
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 2.36
RNA seq_PDX2_SHP099 2.33
mRNA sequencing of highly and lowly metastatic human colorectal cancer PDXs 2.25
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 2.25
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 2.24
RNA-seq of IL-4 stimulated human keratinocytes 2.23
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 2.19
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 2.18
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 2.13
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 2.11
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 2.07
Primate-specific gene TMEM14B promotes cortical expansion and folding 2.04
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4 2.04
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 2.04
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 2.0
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 2.0
Dissecting the single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancer [10x genomics] 1.98
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 1.96
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 1.95
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 1.86
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [H1 RNA-seq] 1.85
Dilated cardiomyopathy vs Myocarditis 1.79
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 1.78
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 1.78
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 1.78
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 1.77
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 1.76
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 1.76
RNA-seq data 1.76
Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2 1.74
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 1.72
Induction of Cardiomyocyte Proliferation [pz-822_human] 1.72
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 1.7
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 1.64
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 1.61
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 1.6
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 1.55
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 1.55
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 1.55
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 1.55
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 1.55
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 1.52
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation 1.46
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 1.37
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 1.31
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 1.29
Interphase condensins regulate ligand-depedent enhancer activation 1.25
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 1.25
Identification of miRNA-mRNA regulatory network for Human Atrial Aging 1.24
Identification of miRNA-mRNA regulatory network for Human Atrial Aging [mRNA] 1.24
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 1.24
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 1.23
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 1.16
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 1.15
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 1.15
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 1.13
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 1.11
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.1
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 1.09
Transcriptomic analysis of human coronary artery endothelial cells stimulated with TNF-alpha in the presence and absence of ACSL3 siRNA 1.08
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.01
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 0.97
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 0.94
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 0.93
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 0.88
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 0.85
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 0.84
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 0.84
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 0.8
Human Treg IL-12 stimulation 0.8
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 0.78
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 0.78
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.75
Gene expression regulated by CSA and CSB in neuroblastoma cell line 0.72
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 0.72
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.7
Profiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis 0.69
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 0.68
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.65
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.65
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 0.65
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 0.65
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 0.64
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 0.63
Iron response of HepG2 cells 0.61
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and converts them into tumorigenic cells 0.6
Determining mRNA half-lives on a transcriptome-wide scale 0.59
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.58
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 0.55
Preclinical model of obesity and ER-positive breast cancer 0.53
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.49
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.47
HBEC-shp53-PCHD7 0.47
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.47
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 0.46
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 0.45
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 0.43
Generation and persistence of human tissue-resident memory T cells in lung transplantation 0.39
Transcriptional landscape changes during human embryonic stem cell derivation 0.38
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 0.37
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.36
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.31
RNA-seq analysis of control and Myc-induced U2OS cells 0.3
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.3
An siRNA screen identifies CHD4 as a target for epigenetic therapy 0.27
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.26
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 0.22
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 0.19
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 0.16
Integrated epigenomic and transcriptomic profiling of terminal human erythropoiesis [TMCC2] 0.15
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 0.14
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.11
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 0.1
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.06
Modulation of nonsense-mediated decay by rapamycin 0.05
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.05
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.04
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.04


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