Gene Query: E2F6

Dataset Description Geneva Score
Tracking of dCas9-methyltransferase footprints 22.05
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 19.44
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation [RNA-Seq] 18.89
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation 18.89
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 18.26
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 12.57
BASP1 modifies the Tamoxifen response 12.25
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 12.1
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 11.38
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 11.01
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 10.82
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 10.61
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 10.61
Nucleoporin-mediated regulation of cell identity genes 10.52
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 9.54
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 9.53
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 9.37
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 9.37
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 8.86
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 8.85
RNA-seq analysis to identify the genes regulated by p53-SET interplay 8.82
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 8.82
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 8.64
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 8.6
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 8.53
A transcriptome-wide divergence in protein translation scales with LIN28B expression 8.26
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 7.8
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 7.74
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 7.38
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 7.19
The Human Testis Cell Atlas via Single-cell RNA-seq (Healthy men scRNA-seq data set) 7.19
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 7.11
Noncoding regions are the main source of targetable tumor-specific antigens 6.68
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 6.52
Co-transcriptional loading of RNA export factors shapes the human transcriptome 6.25
RNAseq of HEK293 cells after Chtop knockdown 6.25
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 6.19
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 6.18
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 6.14
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 5.99
Neonatal and adult human testis defined at the single-cell level 5.96
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 5.93
Estrogen Receptor Beta Impacts Hormone-Induced Alternative mRNA Splicing in Breast Cancer Cells 5.85
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 5.8
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 5.8
DART-seq: an antibody-free method for global m6A detection 5.79
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 5.47
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 5.47
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 5.47
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 5.45
Single-nucleotide-resolution mapping of HBV promoters using CAGE 5.25
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 5.22
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 5.15
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 5.07
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 4.89
Effect of drugs on transcriptomic profiles 4.87
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 4.86
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 4.86
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 4.82
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 4.81
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 4.73
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 4.73
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 4.69
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 4.69
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 4.68
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 4.68
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 4.65
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 4.61
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 4.61
Exercise-induced transcriptome changes in skeletal muscle adapted to aerobic training 4.59
Role of COP1 on MAP kinase transcriptional output in melanoma 4.59
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 4.58
SUV420H2 knockdown in PANC-1 4.54
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 4.46
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 4.46
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 4.41
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 4.41
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 4.38
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 4.36
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 4.33
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 4.29
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 4.26
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 4.22
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 4.21
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 4.15
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 4.15
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 4.11
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 4.08
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 4.08
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 4.05
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 3.99
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 3.97
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 3.95
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 3.88
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 3.85
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 3.81
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 3.79
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 3.79
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 3.79
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 3.78
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 3.78
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 3.78
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 3.75
MCF-7 as a model for functional analysis of breast cancer risk variants 3.67
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 3.57
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 3.57
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 3.57
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 3.57
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 3.55
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 3.55
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 3.55
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 3.5
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 3.49
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 3.48
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 3.48
Gene expression in PANC1 cells treated with Rakicidin 3.43
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 3.43
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 3.43
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 3.38
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 3.38
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 3.38
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 3.37
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 3.36
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 3.35
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 3.35
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 3.33
Uridylation by TUT4 and TUT7 marks mRNA for degradation 3.31
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 3.26
Genome-wide analysis of herpes simplex virus type 1 (HSV-1) infected cells 3.25
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 3.24
RNAseq Study in CC-671 Treated Cal-51 Cells 3.21
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 3.18
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 3.15
RNA-seq in HepG2 and IMR90 cells 3.15
Evolution of a transcriptional regulator from a transmembrane nucleoporin 3.15
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 3.14
Genetic-to-epigenetic Therapy for Pancreatic Cancer 3.06
SLAM-seq for K562 endogenous mRNA decay 3.05
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 3.04
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 3.04
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 3.03
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 3.02
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 3.02
RNAseq Analysis in glioblastoma cells treated with Mepazine 3.01
RNA splicing alteration on glioblastoma and normal neural stem cells 3.01
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes 3.01
Histone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq] 3.01
Spliceosomal disruption of the non-canonical BAF complex in cancer 3.01
RNA-seq differential expression studies: more sequence, or more replication? 2.99
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 2.98
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 2.97
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 2.97
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 2.95
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 2.95
FBXW7 modulates stress response by post-translational modification of HSF1 2.95
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 2.95
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 2.93
Novel Targeting of Transcription and Metabolism in Glioblastoma 2.93
RIG-I and MDA5 fRIP during KSHV lytic reactivation 2.87
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 2.85
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 2.85
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 2.83
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 2.82
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 2.81
IDH3a KO RNA-seq 2.79
Transcriptional profiling of LS1034 cells treated with tepoxalin 2.78
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 2.74
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 2.73
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 2.7
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 2.67
Transcriptome analysis of BAP1 knockout and restoration 2.66
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 2.66
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 2.65
Nrf2 regulated genes in A549 cells 2.64
Identification of Nrf2 regulated genes by RNA sequencing 2.64
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 2.63
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 2.63
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 2.62
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 2.6
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 2.58
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 2.57
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 2.57
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 2.57
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 2.56
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 2.56
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 2.56
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 2.55
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 2.55
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 2.55
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 2.53
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 2.53
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 2.49
MYCL and EP400 are required for Max and MCPyV mediated gene activation 2.48
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 2.47
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 2.46
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 2.45
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 2.44
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 2.44
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 2.43
RNA expression following TMPRSS11B overexpression or depletion 2.42
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 2.41
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 2.4
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 2.39
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 2.38
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 2.36
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 2.36
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 2.35
Differential Gene Expression between MCF10A and MCF7 cells 2.34
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 2.34
CD95/Fas ligand mRNA is toxic to cells 2.33
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 2.33
Seletive inhibition of CDK9 in DLBCL cell lines 2.33
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 2.33
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 2.31
The role of FAM46C in myeloma cells [sequencing] 2.3
The role of FAM46C in myeloma cells 2.3
Conservative alteration of chromosomal expression pattern across human solid tumor types 2.3
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 2.29
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 2.29
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 2.29
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 2.29
The transcriptome and chromatin accessbility landscape of mammalian germline 2.28
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 2.27
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 2.26
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 2.25
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 2.25
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 2.25
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 2.24
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 2.23
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 2.23
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 2.23
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 2.22
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 2.2
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 2.19
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 2.19
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 2.18
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 2.17
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 2.16
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 2.15
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 2.13
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 2.13
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 2.12
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 2.11
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 2.11
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 2.11
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 2.09
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 2.08
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 2.06
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 2.06
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 2.02
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 2.02
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 2.01
Androgen Receptor-regulated genes in prostate cancer cells 1.99
RNA-seq profiling identifies Androgen Receptor-regulated genes in prostate cancer cells 1.99
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 1.97
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 1.96
Silencing p300 in MCF7 cells to study expression and alternative splicing 1.95
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 1.91
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 1.91
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs 1.91
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs (expression) 1.91
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 1.91
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 1.91
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 1.89
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 1.88
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 1.88
Overexpression of NFIB and YBX1 in MCF-7 cells 1.87
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 1.87
RNA-seq analysis of BAP1-depleted uveal melanoma cells 1.87
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 1.86
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 1.85
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 1.82
m6A-dependent regulation of messenger RNA stability 1.82
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 1.82
scRNASeq analysis of cycling cardiomyocytes 1.8
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 1.8
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 1.8
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 1.78
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 1.78
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 1.77
hnRNP C is a key regulator of protein synthesis in mitosis 1.74
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 1.74
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 1.74
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 1.74
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 1.7
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 1.7
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 1.7
Genome-wide chromatin analysis of Ewing sarcoma 1.7
snRNAs as regulators of alternative splicing 1.7
ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq) 1.7
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 1.69
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 1.69
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 1.69
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 (RNA-Seq) 1.68
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 1.68
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 1.67
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 1.66
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 1.65
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 1.65
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 1.63
Gene expression in GBM with Cav3.2 inhibition 1.63
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 1.63
A single cell reference map for human blood and tissue T cell activation 1.61
Functional role of CPPED1 in trophoblasts. 1.59
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 1.58
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 1.58
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 1.58
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 1.54
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 1.53
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 1.53
CDK12 mediated transcriptional regulation in U2OS cells 1.52
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 1.52
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 1.49
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 1.49
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 1.48
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 1.48
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 1.47
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 1.47
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 1.46
RNA seq comparison between scrambled and shGRP78 cells 1.45
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 1.44
ENCODE Cold Spring Harbor Labs Long RNA-seq 1.42
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 1.4
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 1.4
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 1.39
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 1.39
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 1.38
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 1.37
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 1.37
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 1.37
Effect of PRDM11 depletion in U2932 cells 1.37
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 1.35
A MYC/GCN2/eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer 1.34
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 1.34
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 1.33
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 1.33
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 1.32
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 1.32
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 1.32
Single-cell analysis of adult human ovary using 10X genomics 1.3
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 1.3
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 1.3
CD74 role in transcription regulation 1.28
CD74 role in transcription regulation [RNA-seq] 1.28
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.28
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 1.27
An integrative analysis of non-coding regulatory DNA variations associated with autism 1.27
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 1.26
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 1.25
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 1.24
RNA sequencing of human mammary epithelial cells 1.22
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 1.21
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 1.21
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 1.2
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 1.2
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 1.2
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 1.19
Downregulation of DDX5/DDX17 and REST 1.17
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 1.17
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 1.16
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 1.16
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 1.15
Hypoxic transcriptome of SQ20B human head and neck cancer cells 1.14
Uridylation by TUT4 and TUT7 marks mRNA for degradation [RNA-Seq] 1.13
Determining mRNA half-lives on a transcriptome-wide scale 1.13
A20 regulates canonical wnt-signaling through an interaction with RIPK4 1.11
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells via Transcription Factor Conversion of Hemogenic Endothelium 1.1
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 1.09
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 1.09
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 1.09
Gene expression profile of multiple myeloma cell lines treated with CB-5083 1.08
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 1.06
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 1.03
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 1.03
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 1.03
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 1.02
Tracing Enhancer Networks using Epigenetic Traits (TENET) 1.01
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 1.01
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 1.01
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 1.01
Functional significance of the HIV-1 Tat signature amino acid residues 1.0
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 0.97
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 0.97
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 0.97
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.96
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 0.94
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 0.93
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 0.92
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 0.9
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 0.88
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 0.87
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 0.87
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 0.82
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 0.82
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.81
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.81
The role of CFTR in islet function 0.81
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 0.8
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.8
RNA-Seq of PRMT1 overexpression ECA109 cells 0.79
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 0.78
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 0.77
O-glcnAc reprograms cellular energetics 0.75
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.75
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 0.73
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.72
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 0.72
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 0.7
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  0.7
Real-time observation of light-controlled transcription in living cells 0.69
PTHrP overexpression in MCF7 cells 0.67
Active translatome profiling with RiboLace in MCF7 cells 0.66
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 0.64
Transcriptome-wide modulation of splicing by the exon junction complex 0.63
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 0.63
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 0.63
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.62
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 0.61
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.6
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 0.6
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 0.59
Loss of the Chr16p11.2 candidate gene QPRT leads to aberrant neuronal differentiation 0.58
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.58
KSDM1b Role in Ewing Sarcoma 0.58
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 0.57
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 0.57
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.54
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 0.53
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.52
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 0.52
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 0.51
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 0.51
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 0.51
Next generation sequencing of small RNAs isolated from exosomes in human semen 0.5
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 0.5
Interaction between mitoNEET and NAF-1 in cancer cells 0.49
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 0.49
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 0.48
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 0.45
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 0.45
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 0.45
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.44
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.44
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 0.42
FOXP1 orchestration of ASD-relevant signaling pathways. 0.41
p53 activity results in DNA replication fork processivity 0.41
Myc activation coordinates gene transcription and protein translation responses 0.41
RNA sequencing of T-ALL (COG study) 0.4
Analyses of T-ALL (COG study) 0.4
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.39
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 0.39
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 0.38
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.38
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 0.38
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 0.38
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 0.37
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 0.36
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 0.36
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 0.36
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.36
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.31
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 0.31
mRNA recovered upon RNF219 IP. [RNA-IP] 0.28
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 0.28
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 0.28
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 0.27
SNHG5 siRNA knock down in HCT116 cells 0.27
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 0.27
LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression 0.25
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 0.25
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.25
Role of FGFR1 in neuronal devlopment 0.24
Primate-specific gene TMEM14B promotes cortical expansion and folding 0.22
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.2
Differential Protein Occupancy Profiling of the mRNA Transcriptome 0.19
Expression analysis of genes modulated after knock-down of lncRNA CHROME. 0.17
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 0.17
Direct Isolation and Characterization of Human Nephron Progenitors. 0.16
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.15
JAK dependent survival of ALK- ALCL 0.14
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.12
RNA expression analysis upon JMJD1C depletion 0.12
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 0.12
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.11
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 0.11
Discovering human diabetes-risk gene function with genetics and physiological assays 0.11
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.09
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.06
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 0.05
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 0.05
Intrinsic histone acetyltransferase activity of BRD4 is responsible for nucleosome eviction and transcriptional activation 0.03
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.03
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 0.03
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.03
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.03
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.03
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.03
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.01
RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq] 0.01
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 0.0


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