Gene Query: EGR1

Dataset Description Geneva Score
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 771.58
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 771.58
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 550.23
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 465.33
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 2h] 359.31
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 290.04
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 262.71
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 259.66
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function 252.35
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 245.83
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 244.64
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 231.74
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 220.65
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 217.56
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 217.56
POU2AF1 Functions in the Human Airway Epithelium to Regulate Expression of Host Defense Genes [RNA-Seq] 215.94
POU2AF1 Functions in the Human Airway Epithelium to Regulate Expression of Host Defense Genes 215.94
Selective suppression of endothelial cytokine production by progesterone receptor [RNA-seq] 213.56
Selective suppression of endothelial cytokine production by progesterone receptor 213.56
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 210.59
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 207.82
Human HAP1 cells before and after nutrient deprivation 207.82
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 201.19
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 196.84
Identification of IL-27 as potent regulator of inflammatory osteolysis associated with vitamin E-blended ultra-high molecular weight polyethylene debris of orthopedic implants 194.36
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 181.42
Effect of PRDM11 depletion in U2932 cells 170.6
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 169.01
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 161.74
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 161.74
Transcriptome analysis in Neobractatin treated cells 154.99
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 154.43
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 153.96
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 153.66
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 150.66
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 150.66
Tracking of dCas9-methyltransferase footprints 146.86
VAMP8 contributes to TRIM6-mediated type-I interferon antiviral response upon West Nile virus (WNV) infection 146.54
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 137.54
Transcriptional profiling of LS1034 cells treated with tepoxalin 129.09
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 128.52
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 127.36
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 127.14
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 125.42
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 122.57
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 118.92
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 118.6
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 116.29
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 113.02
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 109.79
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 109.06
mRNA-Seq profiling of human developing kidney 108.3
PGE2 mediated gene expression changes in human cervical stromal cells 107.61
RNA sequencing of human fibroblasts after SUPT4H1 siRNA treatment 107.14
RNA-sequencing analysis examining how the Vibrio cholerae MARTX toxin and its inidividual effector domains modulate the transcriptome of human intestinal epithelial cells. 106.87
Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer 105.01
Argonaute proteins couple chromatin silencing to alternative splicing 104.91
Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) 104.91
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 97.93
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 97.59
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 96.45
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 95.04
RNA-seq of naive and primed ES cells (NHSM) 93.5
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 91.71
RNA-seq analysis of A498 cell line treated with siSETD2 or si-NC 91.5
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 91.46
Effect of ILF3 on translation during homeostasis and the antiviral response 86.29
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 85.67
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 85.36
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 84.96
Gene expression analysis of immortalized human liver progenitor-like cells in culture 84.06
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 83.76
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 83.76
Gene expression profile of human iPSC-derived nephron progenitor cells 83.75
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 81.53
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 81.24
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 24h] 79.35
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 78.69
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 78.5
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 78.11
Identification of mesothelial-to-mesenchymal gene signature in ascitic fluid-isolated mesothelial cells through RNA-sequencing 77.65
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 77.4
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 77.19
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 77.19
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 76.63
LncRNA-GAS5 negative regulation of YAP-target genes expression 76.44
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 75.95
RNA-sequencing of human liver tissue 75.72
RNA sequencing of GlyH-101-treated MCF-7 cell line 75.58
G-quadruplex structures mark human regulatory chromatin 74.58
RNA-seq in transgenic cells 73.82
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 73.01
Controlling for gene expression changes in transcription factor protein networks. 72.36
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 71.14
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq) 70.93
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation 70.93
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] 70.9
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells 70.9
R430: A potent inbibitor of DNA and RNA viruses 70.69
Identification of gene signature in ascitic fluid-isolated mesothelial cells from high grade serous ovarian cancer patients 70.69
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes 70.64
Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein, IFITM3 70.55
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 70.32
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 70.3
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 70.15
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 70.12
Transcriptome-wide identification of CELF2 functional targets in T cells 70.06
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 69.97
EGR1-controlled transcriptome of T HESCs 69.87
Identification of the role of polydom in neurofibromas 69.68
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 69.4
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 69.36
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 68.69
UBC9 knockdown in bladder cancer T24 cell lines 67.99
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 67.97
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 67.97
Gene expression changes upon drug withdrawal (Mel888 cell line) 67.69
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 66.32
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 65.89
Role of COP1 on MAP kinase transcriptional output in melanoma 65.34
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 64.85
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 64.85
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 64.74
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 64.56
Genome-wide analysis of Dengue virus 2 infected cells 64.33
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 63.8
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 63.68
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 63.66
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 63.66
Global transcriptome analysis of HAP1 cells 63.31
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 62.48
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 62.35
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 61.82
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 61.48
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 61.35
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 61.26
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 60.97
Regionally specified human pluripotent stem cell-derived astrocytes 60.9
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 60.19
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 59.89
Characterization of parental and rociletinib-resistant derived H1975 cell lines 59.77
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 58.68
U2AF1 mutations alter splice site recognition in hematological malignancies 58.67
Gene expression analysis upon mtDNA depletion 58.63
Gene expression analysis upon mtDNA depletion [RNA-seq] 58.63
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 58.3
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 58.29
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 57.84
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 57.84
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 57.24
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 57.02
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 57.02
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 56.28
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 56.13
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 56.13
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 55.98
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 55.86
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 55.55
A transcriptome-wide divergence in protein translation scales with LIN28B expression 55.5
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 55.42
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 55.42
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 55.02
4sU-seq of HFF exposed to salt and heat stress 54.99
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 54.96
Large-scale profiling of intracellular signalling pathway activation reveals major distinctions between airway smooth muscle cells of asthmatics and non-asthmatics. 54.94
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 54.14
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 53.85
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 53.82
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 53.47
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 53.47
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 53.46
Gene expression in GBM with Cav3.2 inhibition 52.79
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 52.71
Impact of dieldrin on transcription in Jurkat T cells 52.68
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 52.13
Human embryonic stem cells in E8 and AKIT culture medium 52.13
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 51.28
Gene expression in PANC1 cells treated with Rakicidin 50.8
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 50.32
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 50.28
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 49.95
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 49.58
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 49.55
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 49.37
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 49.37
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 49.1
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 48.89
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 48.89
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 48.89
Tumor exosome integrins determine organotropic metastasis 48.79
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 48.76
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 48.08
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 47.97
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 47.39
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 47.36
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 47.31
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 47.16
Regulation of Lipids is Central to Replicative Senescence 46.16
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 46.15
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 46.09
Endometrial transcriptome and PGR cistrome in cycling fertile women 45.93
Endometrial transcriptome and PGR cistrome in cycling fertile women [RNA-seq] 45.93
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 45.78
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 45.78
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 45.64
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 45.64
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells [RNA-Seq] 45.51
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells 45.51
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 45.51
RNA-seq of human aneuploid cell lines with Trisomy 21 45.38
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 45.16
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 44.66
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 44.63
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 44.48
Human serum and heparin-free platelet lysate as appropriate xeno-free alternatives for production of human MuStem cell batches 44.44
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 44.25
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 44.25
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 43.87
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 43.75
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 43.37
Energy Metabolism during Anchorage-Independence 43.09
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 42.95
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 42.77
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 42.58
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 42.55
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 42.27
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 42.27
AMPK signaling for naïve pluripotency [Hs] 42.26
AMPK signaling for naïve pluripotency 42.26
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 41.98
Analyses of a panel of transcripts and construction of RNA networks in hepatocellular carcinoma 41.61
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 41.47
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 41.38
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 41.11
Morphological and molecular characterization of human dermal lymphatic collectors 40.79
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 40.36
Cellular recruitment by podocyte-derived pro-migratory factors in assembly of the human renal filter 40.25
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 40.23
RNAseq Analysis in glioblastoma cells treated with Mepazine 40.07
Functional role of SLIT2 and ROBO1 in trophoblasts 40.02
The chromatin modifier CHD8 targets autism risk genes during human neurodevelopment  39.91
Illumina sequencing of vaginal epithelial cells from women using depot medroxyprogesterone acetate or non-hormonal contraception 39.84
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 39.78
Gene expressions of H9s in different culture systems 39.48
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 39.47
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 39.02
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 38.96
RNA-sequencing of human tendon after injury 38.92
Discovery and verification of liver cancer marker genes and variable scission based on second-generation sequencing data analysis 38.9
RNA-seq analysis of control and Myc-induced U2OS cells 38.74
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 38.73
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 38.71
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 38.51
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 38.42
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 38.4
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 38.37
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 38.1
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 38.06
Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis 37.87
Depicting early human development and germ cell origin with porcine embryos 37.84
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 37.15
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 36.66
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 36.66
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 36.42
The interplay between SOX4 and SMAD3 in the context of breast cancer 36.32
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 36.31
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 36.31
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs (expression) 36.09
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs 36.09
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) reprograms melanoma microenvironment to promote antitumor T cell responses 36.06
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 35.92
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 35.79
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 35.73
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 35.64
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 35.42
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 35.08
Identification of Sin3B regulated genes during quiescence 34.97
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 34.65
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 34.57
Transcriptome analysis of eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyps reveals distinct lncRNA expression profiles 34.54
Targeting MTHFD2 in Acute Myeloid Leukemia 34.43
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 34.37
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 34.29
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 33.85
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 33.81
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 33.74
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 33.68
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 33.67
Human neutrophil genome during PMA- and E. coli encounter-induced activation 33.67
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 33.56
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 33.56
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 33.43
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 33.25
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 33.25
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution 33.07
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 32.9
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 32.79
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 32.18
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 31.94
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 31.79
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 31.69
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 31.62
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 30.99
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 30.99
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 30.87
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 30.65
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 30.44
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 30.27
A novel target of EZH1/2 for treatment of mantle cell lymphoma 30.06
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 30.06
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 30.06
Novel Targeting of Transcription and Metabolism in Glioblastoma 29.96
Integrated epigenomic and transcriptomic profiling of terminal human erythropoiesis [TMCC2] 29.82
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 29.81
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 29.77
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 29.08
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 29.08
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 29.06
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 29.06
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 28.99
Next Generation Sequencing Study of Circadian Changes in Transcriptome of Human Pineal Gland 28.95
Transcriptome sequencing of K-562 cells 28.86
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 28.47
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 28.16
Transcriptome analyses of human pancreatic islets and pseudoislets 27.55
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 27.52
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 27.48
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 26.52
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 26.37
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 26.33
Role of FGFR1 in neuronal devlopment 26.22
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 26.07
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 26.07
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 25.5
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 25.47
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 25.32
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 24.98
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 24.94
Characterization of the Merkel cell carcinoma miRNome 24.71
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 24.68
Loss of the Chr16p11.2 candidate gene QPRT leads to aberrant neuronal differentiation 24.61
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 24.46
Recovery and analysis of nascent RNA 24.46
Transcriptional profile in human S. haematobium infection 24.43
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 24.42
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 24.42
Generation of trichogenic adipose-derived stem cells by expression of three factors 24.34
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 24.12
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 23.89
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 23.84
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 23.84
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 23.75
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 23.75
Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis 23.69
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole] 23.17
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 23.03
ARID1A and ARID1B loss in HCT116 and TOV21G cells 22.99
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 22.86
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 22.5
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 22.43
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 22.43
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 22.21
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 21.95
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 20.97
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 20.79
Transcriptomic analysis of human tonsillar TFH subsets 20.78
TFAP2C signalling in human fibroblasts 20.58
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 20.41
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. 20.01
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism: Liver RNA profiles of lean non-diabetic, obese non-diabetic as well as obese diabetic humans. 20.01
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 19.26
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 19.25
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 19.25
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 18.95
Gene Expression Signature in Adipose Tissue of Acromegaly Patients 18.95
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 18.92
Changes in human endometrial gland transcriptome over the window of implantation 18.91
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 18.82
RNA sequencing of human mammary epithelial cells 18.55
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 18.48
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 18.48
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 18.48
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 18.45
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 18.33
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 18.13
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 18.03
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 17.89
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 17.56
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 17.07
RNAseq analysis of the human neutrophil transcriptome, with and without in vitro cytokine stimulation 16.94
An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch Type Alopecia Areata, Totalis and Universalis 16.74
Identification of renal resident macrophages across species [C1] 16.24
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 16.23
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 15.81
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 15.53
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 15.4
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 14.48
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 14.43
The Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth 14.42
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 14.32
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 14.31
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 13.86
The transcriptomic landscape of MAIT cell development in the thymus (C006 RNAseq data set) 13.62
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 13.34
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 13.24
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 13.19
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 13.19
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 13.03
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 12.9
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 12.9
Modeling Human Cancer-induced Cachexia (Human) 12.86
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 12.84
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 12.66
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 12.6
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 12.49
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 12.49
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 12.35
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 12.05
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 12.05
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 11.45
Characterization of Human Pegivirus Infection in Liver Transplantation Recipients 11.34
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 11.3
Gene expression in skeletal muscle in older individuals subject to ten days of complete bed rest. 11.27
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 11.23
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 11.23
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 11.15
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 11.14
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding 10.96
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 10.63
RNA-Seq analysis of human neutrophils isolated by different protocols (Polymorphprep and negative selection) and incubated with and without in vitro cytokine stimulation 10.53
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 10.29
Aortic Valve Tissue: Stenosis vs. Sclerosis 10.25
Alagille_Nodder 10.13
RNA Seq of Alagille liver biopsies 10.13
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 10.1
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 10.09
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 9.85
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 9.85
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 9.63
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 9.56
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 9.42
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 9.28
CDK12 mediated transcriptional regulation in U2OS cells 8.9
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 8.61
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 8.43
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 8.34
Identification of differentially expressed genes between senescence and senescence bypass cells 7.89
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 7.64
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 6.82
Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy 6.81
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 6.76
Evaluating pre-clinical models for studying NASH driven HCC. 6.63
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 6.39
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 6.31
RNA-seq of IL-4 stimulated human keratinocytes 6.23
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 6.12
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 6.11
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 5.83
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 5.83
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 5.46
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 5.33
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 5.3
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 5.13
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 4.92
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 4.54
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I 4.39
The DPYSL2 gene connects mTOR and schizophrenia 4.33
Entrectinib Resistance in a Neuroblastoma Xenograft Model 4.24
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 3.82
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 3.72
RNA-sequencing of healthy human skeletal myocytes 3.65
Differentially Expressed Genes for Atrial Fibrillation Identified using RNA Sequencing from Paired Human Left and Right Atrial Appendages. 3.58
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 3.29
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 3.29
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells II 3.24
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 3.16
The role of the Calcium-Sensing receptor in colorectal cancer 3.05
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 2.98
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) [RNA-seq] 2.95
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) 2.95
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 2.91
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels 2.9
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq] 2.9
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 2.43
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 2.32
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 2.03
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 1.29
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 1.22
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 1.22
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 1.2
Gene expression profile of CRC-derived HILEC 1.19
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 1.16
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 1.16
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 1.01
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 0.93
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 0.87
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 0.58
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.56
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.35
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 0.25


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