Gene Query: EPB41L3

Dataset Description Geneva Score
Effect of Hotair overexpression in human breast cancer cell lines 357.2
Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine 202.87
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 105.76
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 82.5
IDH3a KO RNA-seq 77.28
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 73.28
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 65.41
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene 63.02
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene (RNAseq) 63.02
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 62.49
RNA-seq analysis of AML cells in response to ASLAN003 59.84
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 57.02
Ectoderm specification of H1 human embryonic stem cells 56.8
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 56.61
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 56.61
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 53.21
hTERT promotes cell adhesion and migration independent of telomerase activity 52.14
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 51.42
Gene expression changes associated with resistance to tagraxofusp (SL-401) 50.55
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 47.31
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 47.11
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 46.75
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 44.57
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 43.0
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 40.05
RNA-seq of overgrown interscapular adipose tissue with biallelic MFN2 mutations 39.94
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 38.86
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 38.84
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 38.57
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 37.0
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 36.5
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 35.24
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 35.08
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 35.0
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 34.98
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 34.98
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 34.1
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 34.07
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 33.79
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 33.31
Chromatin-informed inference of transcriptional programs in gynecologic cancers 33.31
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 33.31
RNA-seq of young and quiescent MRC-5 human fibroblasts 32.69
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 32.42
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 31.78
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 31.63
Viral infection enhances NK cell activation via Type I dependent pathways and can be utilized to enhance influenza-specific monoclonal antibody therapies 31.56
Transcriptome analysis revealed impaired cAMP responsiveness in PHF21A-deficient human cells 31.18
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 30.53
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 30.53
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 30.17
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 30.04
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 28.04
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 27.7
Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids 27.28
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 27.14
RNA-seq and Microarray in Transcriptome Profiling of Anterior Cruciate Ligament Tears: Implications for Prognostic Biomarkers Discovery 26.65
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 26.46
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 26.37
CircRNAome diversity in human mature B-cells, T-cells and monocytes 26.33
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 25.17
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 25.17
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 25.17
RNA sequencing to compare gene expession in control and PF228-treated hepatic stellate cells 25.13
RNA-seq of stable and unstable section of human atherosclerotic plaques 24.89
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 24.86
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 24.66
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 24.39
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche 24.13
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. 24.1
Identification of monocyte-like precursors of granulocytes as a mechanism for accumulation of PMN-MDSC in cancer 24.02
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 23.43
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 23.43
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 23.24
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 23.24
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 23.23
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 22.9
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 22.72
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq] 22.58
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 22.48
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 22.26
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells 22.18
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells [RNA-Seq] 22.18
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 22.17
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 22.05
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 21.67
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 21.67
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 21.62
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing [RNA-seq] 21.58
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing 21.58
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 21.42
RNA-sequencing of formalin fixed human primary melanoma tissue 21.34
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 21.29
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 21.23
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 21.23
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 21.05
21.02
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 20.71
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 20.63
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 20.55
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 20.55
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 20.48
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 20.34
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 20.34
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 20.34
Regulation of Lipids is Central to Replicative Senescence 20.29
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 20.25
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 20.25
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 20.18
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 20.16
Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels 20.15
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 20.09
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 19.93
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 19.88
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  19.86
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 19.68
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 19.63
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 19.44
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 19.36
Epigenome regulation during epidermal lineage commitment [RNA-seq] 19.25
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 19.02
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 18.97
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 18.81
Derivation of ventrical and atrial cardiomyocytes and maturation using biowires 18.79
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 18.43
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 18.4
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 18.38
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 18.24
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 17.99
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 17.99
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 17.78
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 17.66
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 17.31
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 17.29
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 17.29
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 17.21
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 17.19
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 17.1
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 16.97
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 16.92
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 16.9
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 16.89
Investigation about fibroblasts of different origins in culture 16.85
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 16.78
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 16.73
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 16.53
hnRNP C is a key regulator of protein synthesis in mitosis 16.2
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 16.17
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 16.17
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 16.11
AQP5-Expressing Cells Serve as Stem Cells and Cancer Origins in the Distal Stomach 16.1
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 15.97
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 15.96
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 15.96
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 15.93
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 15.75
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 15.74
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 15.74
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 15.58
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 15.41
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 15.29
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 15.28
DIGIT regulates endoderm differentiation of human embryonic stem cells 15.23
Global analysis of alternative splicing regulated by RBM10 15.21
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 15.12
Regionally specified human pluripotent stem cell-derived astrocytes 15.1
PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells 14.99
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 14.96
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 14.95
The dynamic landscape of coding and non-coding RNAs in the innate immune response to microbial pathogens 14.91
RNA-seq analysis of A498 cell line treated with siSETD2 or si-NC 14.9
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 14.9
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 14.8
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 14.56
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 14.56
DJ-1 is dispensable for human stem cell homeostasis 14.51
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 14.49
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 14.28
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 14.28
Genome-wide analysis of the Integrator complex 14.18
Genome-wide analysis of the Integrator complex (HTS) 14.18
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 14.17
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 14.17
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 14.16
Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications 14.1
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 13.77
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 13.77
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 13.7
Chromatin landscape of human visceral and subcutaneous adipocytes 13.67
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 13.46
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 13.46
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 13.43
Global gene expression differences between blood- and lymphatic-specific endothelial colony forming cells 13.38
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 13.38
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 13.3
Proteolytic cleavage by taspase1 and the regulation of the stability of MLL1 13.29
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 13.26
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 13.26
Patient-derived luminal breast cancer xenografts with progestins 13.26
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 13.26
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 13.03
Next Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs 12.9
Spliceosomal disruption of the non-canonical BAF complex in cancer 12.84
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 12.81
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 12.77
Comparing gene expression in iPSC derived RPE from control and AMD donors 12.76
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 12.69
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 12.69
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 12.56
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 12.51
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 12.45
Tyrosine Kinase Inhibitor Cardiotoxicity 12.45
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 12.38
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 12.38
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 12.38
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 12.37
TCF21 and Aryl-hydrocarbon receptor gene cooperate to activate a pro-atherosclerotic gene expression program 12.36
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 12.35
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 12.16
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 12.11
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 12.1
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 12.1
RNA-seq of human iPS derived macrophages with or without KLF1- transcription factor Activation 11.92
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 11.9
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites (RNA-seq) 11.8
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites 11.8
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 11.78
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 11.74
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 11.71
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 11.71
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 11.64
Nonpregnant and term pregnant human myometrial tissues 11.64
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 11.64
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 11.6
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole] 11.56
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress 11.51
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 11.49
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  11.4
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 11.35
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 11.34
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 11.32
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 11.3
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 11.26
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 11.24
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 11.18
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 11.14
Generation of trichogenic adipose-derived stem cells by expression of three factors 11.14
Reprogrammed myeloid cell transcriptomes in NSCLC 11.1
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 11.1
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 11.1
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 11.07
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 11.06
Transcriptome-wide response to synthetic chromatin protein PcTF 11.04
OBESITY IS ASSOCIATED WITH IMPAIRED EXPRESSION OF THE GLYCOSYLTRANSFERASE EOGT IN DECIDUALIZING ENDOMETRIUM 11.02
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 10.95
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 10.93
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 10.89
Role of CD133 molecule in WNT response and renal repair 10.78
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 10.75
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 10.68
A transcriptome-wide divergence in protein translation scales with LIN28B expression 10.67
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 10.67
Alteration of the microRNA network during the progression of Alzheimer’s disease 10.62
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 10.61
Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes 10.58
Next Generation Sequencing of isolated EGFR+ and HLA-G+ first trimester human trophoblasts 10.54
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma [RNA-Seq; normal samples] 10.51
RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d) 10.38
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 10.34
Differetially expressed genes after hTR overexpression in U2OS cells 10.29
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 10.2
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues 10.17
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 10.16
Cell responses to dysregulated VZV-induced cell-cell fusion 10.16
HNF1A deficiency impairs β-cell fate, granule maturation and function 10.16
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 10.16
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 10.15
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 10.14
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 10.1
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 10.1
Exploring the RNA landscape of endothelial exosomes 10.04
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 10.01
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 9.91
Generation and functional characterization of MDSC-like cells 9.88
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 9.87
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation 9.78
Zika virus infection reprograms global transcription of host cells to allow sustained infection 9.6
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 9.58
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 9.47
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 9.47
Gene Expression Signature in Adipose Tissue of Acromegaly Patients 9.43
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 9.39
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 9.32
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 9.32
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 9.13
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 8.95
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 8.95
RNA-Seq analysis of neurons derived from induced pluripotent stem cells reprogrammed from dental pulp 8.93
Mapping interactions for the TNIP2 hub protein 8.93
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 8.89
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 8.8
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 8.73
Transcriptional profile in human S. haematobium infection 8.68
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 8.64
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 8.62
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 8.62
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 8.57
Differential gene expression in Jagged1 treated human dental pulp cells. 8.52
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 8.51
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 8.48
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 8.48
NHLRC1 re-expression in cancer cells 8.37
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 8.36
RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) 8.3
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 8.23
In vitro modeling of human germ cell development using pluripotent stem cells 8.13
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 8.01
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 8.0
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 7.99
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 7.94
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 7.88
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 7.88
Gene expression profile difference among renal location in a stone former 7.82
Transcriptomic Analysis of Endothelial Cells from Fibrovascular Membranes in Proliferative Diabetic Retinopathy 7.77
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 7.76
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 7.73
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 7.73
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 7.73
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 7.68
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 7.67
Gene expression profiling in metabolically heterogeneous human lung tumors 7.56
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 7.51
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 7.4
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 7.4
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 7.21
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_TK] 7.18
Illumina sequencing of vaginal epithelial cells from women using depot medroxyprogesterone acetate or non-hormonal contraception 7.13
In search for materials able to be colonized by a normal endothelium: сharacterization and NGS gene expression profiling of human primary endotheliocytes cultivated on electrospun 3D matrices 7.12
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 7.02
Dissecting neural differentiation regulatory networks through epigenetic footprinting 7.02
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 7.01
Aging-associated patterns in the expression of human endogenous retroviruses 6.98
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 6.95
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 6.94
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 6.91
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 6.91
RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes 6.84
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 6.82
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 6.73
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 6.72
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4 6.49
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 6.48
Transcriptional responses of melanoma cells to BRAF inhibition 6.45
Dysregulated immune system networks in war veterans with PTSD 6.37
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 6.37
Genome-wide expression from the esophageal biopsies of subjects with and without eosinophilic esophagitis 6.33
Expression profiles of the four human major ectodermal lineages 6.3
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 6.14
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 6.14
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 6.09
The effect of slow and rapid H2S production on the levels of LPS-induced proinflammatory mediators and transcription in different human cell cultures 6.04
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 6.0
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 5.96
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 5.88
ADAR1-editing of cellular and measles virus-derived duplex RNA 5.88
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 5.88
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 5.77
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 5.77
Gene expression profiling of human and murine in vitro muscle differentiation 5.77
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis 5.75
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 5.69
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 5.57
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 5.57
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 5.57
ZIKV infection of monocytes activates inflammasome pathways 5.49
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 5.45
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 5.45
FGF2 regulation of gene expression in stable inducible Neurons 5.42
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 5.36
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 5.12
Disruption of GRIN2B impairs differentiation in human neurons 5.11
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 5.03
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 4.98
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 4.97
The role of m6A/m-RNA methylation in stress response regulation 4.97
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 4.95
Investigate A2M treatment on human prostate cancer and mouse liver 4.94
Investigate A2M treatment on human prostate cancer xenograft in mice 4.94
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 4.9
Dynamic reorganization of nuclear architecture during human cardiogenesis [RNA-seq] 4.88
Dynamic reorganization of nuclear architecture during human cardiogenesis 4.88
RNA-seq of CD33 KO and control HSPCs 4.84
Human islets of varying quality: the good, the (not so) bad and the ugly 4.77
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 4.7
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 4.68
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 4.67
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 4.64
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 4.55
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 4.52
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 4.48
Epigenome regulation during epidermal lineage commitment 4.33
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 4.2
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 4.18
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 4.1
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 4.04
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 4.04
Pain-driven transcriptome changes in synovium of knee osteoarthritis patients 3.95
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 3.94
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 3.8
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 3.74
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 3.58
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 3.57
RNA-seq of SCLC PDX models treated with EP 3.57
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 3.47
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 3.47
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 3.46
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 3.43
RNA-seq data 3.42
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 3.4
CDK12 mediated transcriptional regulation in U2OS cells 3.36
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 3.29
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 3.21
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 3.17
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [BAV] 3.13
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 3.12
Enhancement of Arterial Specification in Human Pluripotent Stem Cell Cultures Promotes Definitive Hematoendothelial Program with Broad Myelolymphoid Potential 3.07
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 3.07
Induction of Cardiomyocyte Proliferation [pz-822_human] 2.97
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 2.97
Transcriptome analysis of peripheral blood monocytes 2.93
Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease 2.93
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 2.9
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 2.87
Vammin induces a highly efficient angiogenic response through VEGFR-2/NRP-1 and bypasses the regulatory function of VEGFR-1 2.79
iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension 2.79
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 2.74
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 2.6
Gene expression profiles of ibrutinib-responsive and ibrutinib non-responsive cells in ERBB4 expressing cancer cell lines 2.48
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 2.42
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 2.42
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 2.38
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes 2.37
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq] 2.37
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 2.32
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 2.25
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 2.24
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 2.22
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 2.22
Copper Regulation of HIF-1 Transcription Activity 2.19
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 2.19
Transcriptome sequencing of K-562 cells 2.11
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 2.09
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 2.05
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 2.02
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 2.02
BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage (Gene expression profiling in several tetrapod species, bulk tissue RNA-seq) 1.99
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 1.97
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 1.92
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 1.92
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 1.92
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 1.87
Trascriptome of thyroid cancer-induced macrophages 1.85
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 1.81
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 1.61
Gene expression profile of CRC-derived HILEC 1.55
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 1.52
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 1.44
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 1.43
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 1.25
Expression patterns in chronic thromboembolic pulmonary hypertension 1.23
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 1.22
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 1.17
Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region 1.08
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 1.06
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 1.02
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.96
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 0.94
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 0.91
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 0.9
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.88
BMS-470539 on human synovial fibroblasts 0.84
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 0.82
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 0.75
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 0.73
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 0.7
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 0.69
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 0.61
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 0.55
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 0.54
RNA seq_PDX2_SHP099 0.53
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 0.49
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 0.47
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 0.34
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 0.2
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 0.2
Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products 0.15
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 0.12
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 0.08
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.05
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 0.01


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