Gene Query: EPHB2

Dataset Description Geneva Score
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 97.29
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 72.69
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 65.82
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 65.53
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 65.39
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 57.03
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 55.06
Treatment of SW480 colon cancer cell induced xenografts with AZD and DBZ 54.7
RNA-seq of human fibroblasts after irradiation 52.8
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 52.36
Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine 50.23
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 48.64
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 47.87
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 47.85
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 45.96
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 45.37
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 44.72
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 39.24
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 39.23
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 37.36
Altering cancer transcriptomes using epigenomic inhibitors 37.12
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 37.12
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 36.55
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 36.08
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 35.65
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 35.65
MARS Seq data from human cortical organoids 35.3
Macrophage Ad5f35 M2 Challenge 35.29
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  35.15
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 34.69
RNA sequencing of hPSC-derived cardiac progenitors and endocardium 33.08
Gene Expression Profiling of SPOP Knocked Down Cell 32.57
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 31.44
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 31.15
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 31.15
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 30.77
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 30.77
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 30.27
Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis 30.18
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 29.44
Transcriptome analysis of H9 hESC derived cerebral organoids 28.82
Ectoderm specification of H1 human embryonic stem cells 28.74
Genome-wide DNA accessibility maps and differential gene expression using ChIP-seq, ATAC-seq and RNA-seq for the human secondary fibroblast cell line hiF-T and whole worms with and without knockdown of FACT complex 28.65
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 28.58
Mechanistic Model-Guided Study of Embryonic Morphogenesis 28.39
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 28.39
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 28.16
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 28.13
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 28.04
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 27.61
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 27.22
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 26.92
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 26.88
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 26.67
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 26.14
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 25.1
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 24.41
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 24.27
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 24.27
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 24.09
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 23.97
Transcriptome of Stabilin-1 siRNA transfected human monocytes 23.97
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 23.8
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 23.71
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 23.47
Transcriptome of U251 cells overexpression complement component 7 23.42
Region-specific Innate Antiviral Responses of the Human Epididymis 23.26
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 22.97
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 22.85
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 22.83
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 22.21
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 22.13
TLR2 dimerization blockade allows generation of homeostatic intestinal macrophages under acute colitis challenge 22.08
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 21.84
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 21.84
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 21.8
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 21.68
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 21.66
Macrophage Ad5f35 PhenoMap 21.58
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 21.39
Identification of Sin3B regulated genes during quiescence 21.37
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 21.37
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells 21.21
Control of prostate tumour growth by the long non-coding RNA GHSROS 21.17
Analysis of the Clustered Protocadherin (cPcdh) Locus in Human Pluripotent Stem and Derived Cells [RNA-seq II our of II] 21.16
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 21.05
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization [RNA-Seq] 20.88
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization 20.88
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 20.75
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 20.71
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 20.36
Modeling Trilateral Retinoblastoma using Human Embryonic Stem Cells 20.34
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 20.26
Gene expression changes caused by KRAS in MCF-10A 20.25
Global analyses of the effect of different cellular contexts on microRNA targeting 20.25
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 20.25
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 20.1
Gene expression analysis of immortalized human liver progenitor-like cells in culture 19.93
Transcriptome analysis of Zika infected neural stem cells 19.93
Zika infected neural stem cells 19.93
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 19.83
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 19.81
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 19.81
A novel non-canonical signaling pathway mediates TGF-β1-induced glucocorticoid insensitivity in epithelial cells 19.79
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 19.65
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 19.44
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 19.17
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 19.07
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 18.76
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 18.76
Generation of Patient-Matched Malignant and Normal Primary Cell Cultures from Clear Cell Renal Cell Carcinoma Patients 18.74
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 18.7
Rorc disruption in human FG pancreatic cancer cells 18.29
Dynamic reorganization of nuclear architecture during human cardiogenesis 18.18
Dynamic reorganization of nuclear architecture during human cardiogenesis [RNA-seq] 18.18
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 18.01
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 17.75
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 17.68
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 17.57
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 17.46
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 17.35
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 17.35
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 17.33
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 17.33
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 17.18
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 17.17
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 17.12
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 17.12
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 16.97
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 16.84
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 16.84
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 16.79
Tyrosine Kinase Inhibitor Cardiotoxicity 16.79
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 16.64
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 16.42
A role for ZNF598 in post-transcriptional gene regulation 16.37
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 16.24
RNA-seq analysis to identify the genes regulated by p53-SET interplay 16.23
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 16.17
Next Generation Sequencing Study of Circadian Changes in Transcriptome of Human Pineal Gland 16.07
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 16.02
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells 16.01
RNA-seq analysis of A498 cell line treated with siSETD2 or si-NC 15.98
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 15.9
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 15.7
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 15.68
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 15.67
Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes 15.64
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 15.5
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 15.5
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 15.49
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 15.49
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 15.37
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 15.35
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 15.35
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 15.31
RNA-seq of MCF10A cells and CAF 15.17
Examining serotonergic neuron differentiation from human iPSCs 15.16
Identifying the molecular mode of action of itraconazole in colorectal cancer 15.1
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 15.08
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 15.07
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 15.05
Global expression profiles in cardiac progenitor cells generated by ISX-9 15.05
Transcriptomic profile of human embryonic renal corpuscles 15.03
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 14.77
Effect of mitochondria deficiency on senescence-associated gene expression 14.75
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes 14.68
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [RNA-seq] 14.68
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 14.57
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 14.5
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 14.46
Role of CD133 molecule in WNT response and renal repair 14.43
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 14.43
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 14.27
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 14.27
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 14.24
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 14.21
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 14.16
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 14.06
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 14.04
RNA-seq of young and quiescent MRC-5 human fibroblasts 14.01
Obstructed defecation – an enteric neuropathy? An exploratory study of patient samples 13.98
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses 13.97
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 13.96
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 13.89
A549 cells and MSR-A549 cells 13.89
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 13.79
Global reduction in H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 13.74
A549 cell transcriptome responses to infection with H7N9 influenza virus 13.71
Glioma Stem Cell Specific Super Enhancer Drives Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling 13.69
Transcriptome of EBV-infected gastric cancer cell lines 13.55
GATA3 enhances the neurogenic potential of primary human astrocytes after traumatic injury [exp1] 13.49
Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein 13.49
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 13.47
RNA-seq analysis of RALD iPSCs after in vitro differentiation 13.41
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 13.38
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 13.25
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 13.17
RNA-seq in HepG2 and IMR90 cells 13.16
Evolution of a transcriptional regulator from a transmembrane nucleoporin 13.16
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 13.02
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 13.0
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 12.95
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 12.94
RNA sequencing with KSHV infection and enrichment for circular RNAs 12.91
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 12.85
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 12.85
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 12.78
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 12.73
Molecular Mechanisms of Endothelial Hyperpermeability 12.72
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 12.59
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 12.51
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 12.46
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 12.39
Endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates 12.35
RNA Seq of HMVEC under hypoxia 12.35
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 12.34
Transcriptional responses of human insulinoma cells to acute cytokine exposure 12.31
ARID1A regulates condensin II distribution and chromosomal partition 12.3
ARID1A regulates condensin II distribution and chromosomal partition [RNA-seq] 12.3
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 12.29
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 12.24
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 12.24
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 12.19
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 12.19
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 12.19
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 12.15
Fbxo32 mediated gene expression program underlies EMT and metastasis 12.15
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 12.1
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 12.07
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 12.02
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 12.02
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 12.0
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 12.0
Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli 11.86
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 11.74
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 11.73
Global epigenomic reconfiguration during mammalian brain development 11.68
Methylome, hydroxymethylome, and integrative transcriptome profiling in human CRC tissue and paired normal tissues 11.66
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 11.61
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 11.61
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 11.6
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 11.55
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 11.47
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 11.46
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 11.46
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 11.45
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 11.42
Investigation about fibroblasts of different origins in culture 11.36
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 11.34
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 11.33
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 11.33
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 11.31
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 11.3
RNA-seq analysis and shRNA screen of breast cancer 11.27
RNA-seq analysis of breast cancer 11.27
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 11.27
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 11.26
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 11.26
Neurofibroma 11.09
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 11.09
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 11.09
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 11.07
RNA-seq Transcriptome Analysis of AD169 and AD169-ΔUL26 infected MRC5 fibroblasts. 11.04
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 11.01
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 10.92
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 10.9
TGF-β regulation of miRNA expression in pancreatic cancer 10.89
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 10.86
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 10.84
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 10.83
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 10.8
mRNA expression in human DAOY cells 10.63
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 10.59
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 10.57
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 10.57
Ribosomal footprinting of CN34-Parental and CN34-LM1a 10.51
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 10.5
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 10.48
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 10.39
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 10.36
CSL RNA-Seq on HKC and SCC cell lines 10.28
CSL 10.28
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 10.25
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 10.19
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 10.11
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 10.0
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 9.92
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 9.92
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 9.86
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 9.84
Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation 9.8
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 9.79
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 9.73
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 9.71
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 9.68
Gene expression profile in breast cancer cells 9.67
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 9.67
Nutritional control of protein translation 9.55
Diarrhea in lymphocytic colitis: ERK1/2-dependent ENaC dysregulation and claudin-4-, -5- and -8-related barrier defects 9.48
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 9.45
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 9.35
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 9.3
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 9.3
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 9.27
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 9.27
Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation 9.26
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 9.17
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 9.16
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 9.06
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 9.04
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 9.03
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 9.0
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 9.0
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 8.95
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 8.88
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 8.88
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 8.87
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 8.87
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 8.85
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 8.71
The cohesin complex prevents Myc-induced replication stress 8.67
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 8.66
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 8.55
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 8.4
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 8.35
Nucleoporin-mediated regulation of cell identity genes 8.29
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 8.21
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 8.16
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 8.12
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 8.12
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 8.05
Transcriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy 7.99
Transcriptomics analysis of enteroendocrine cells following vertical sleeve gastrectomy 7.99
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 7.98
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 7.97
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 7.88
Exploring the RNA landscape of endothelial exosomes 7.81
Toxoplasma gondii infection of human retinal pigment epithelial cells 7.75
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 7.72
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 7.7
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 7.7
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 7.69
Gene expression in PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition. 7.69
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 7.69
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 7.67
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 7.57
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 7.42
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 7.4
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 7.38
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 7.3
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 7.17
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 7.09
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 6.97
Gene profiling of human adult and pediatric liver cancer cells 6.92
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 6.86
hESC neural differentiation 6.85
RNA-seq analysis of gene expression patterns during hESC neural differentiation 6.85
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 6.84
mRNA sequencing of oropharyngeal cancer cell lines 6.52
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 6.52
Dissecting neural differentiation regulatory networks through epigenetic footprinting 6.33
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 6.3
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 6.26
H1609088 Human RNA-Sequencing 6.18
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 6.11
PRDM1 inhibits proliferation of human colon cancer organoids 6.1
A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells 5.84
RNA sequencing of human pancreatic cancer cell lines 5.83
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 5.77
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 5.77
Aneuploidy-induced cellular stresses limit autophagic degradation. 5.75
RNA splicing alteration on glioblastoma and normal neural stem cells 5.63
Expression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions. 5.6
Gene expression of thyroid cancer cell lines 5.51
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 5.35
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 5.35
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 5.35
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 5.27
Generation of mature lung alveolar epithelial cells from human pluripotent stem cells 5.24
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 5.2
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 5.2
Genome-wide Analysis of Chromatin Interactions in Human Cells 5.17
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 5.07
CHD1 regulates cell fate determination by activation of differentiation-induced genes 4.91
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 4.89
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 4.79
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 4.79
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 4.77
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 4.76
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 4.76
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 4.75
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 4.75
RNA seq_PDX2_SHP099 4.72
The NFkB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells 4.7
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 4.69
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 4.69
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 4.67
RNA-Seq in PWS iPSC-derived neurons 4.64
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 4.63
mRNA sequencing of highly and lowly metastatic human colorectal cancer PDXs 4.55
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 4.48
Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells 4.32
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 4.31
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 4.26
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 4.26
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 4.22
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 4.19
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 4.19
The interplay between SOX4 and SMAD3 in the context of breast cancer 4.16
The Wnt/β-catenin and RAS-ERK Pathways were Activated in Tissues of Chemotherapy-Resistant Gastric Cancer PDX Tumor 4.12
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 4.08
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 3.9
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 3.9
Transcriptome profiling of 5 human adenocarcinoma cell lines 3.89
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 3.86
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 3.82
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 3.82
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 3.76
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 3.75
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 3.75
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 3.73
Effects of transcription on genome - nuclear lamina interactions 3.73
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 3.72
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 3.57
RNA sequencing analysis of selumetinib-resistant CRC cells lines 3.45
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 3.44
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 3.43
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 3.4
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 3.39
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 3.37
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 3.37
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation 3.3
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes: Singapore Cohort RNA-seq 3.26
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes 3.26
Mesothelioma xenografts in nude mice: PBS treated versus pirfenidone treated 3.16
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 2.81
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 2.78
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 2.78
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 2.64
Impact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST 2.64
Gene expression profile difference among renal location in a stone former 2.61
Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a Colorectal Cancer Patient-derived Tumor Explant Model 2.59
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 2.48
Transcriptomic analysis of human iPS cells derived from fragile X syndrome patients during neural differentiation 2.29
Transcriptional analysis of ZIKV-infected Ifnar-/- and Ifnar+/- placentas and IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 2.21
Analysis of transcriptional differences after IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 2.21
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 2.15
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 2.09
Gene expression analysis of human adenomas. 2.04
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 2.0
Effects of rFVIIIFc on human macrophages 1.91
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 1.59
Zika virus directly infects human peripheral neurons and induces cell death 1.58
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 1.57
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 1.57
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells 1.54
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 1.54
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.54
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.54
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 1.5
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 1.5
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 1.42
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 1.31
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 1.3
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 1.25
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 1.12
FOXP2's impact on the primate transcriptome 1.08
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 1.07
Transcriptome profiling of A2M treated A549 Cell Line Samples 1.06
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 1.06
iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension 1.01
Epigenomic conservation of transposable element silencing [RNA-seq] 0.99
Epigenomic conservation of transposable element silencing 0.99
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells II 0.97
Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney 0.89
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 0.88
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.77
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 0.77
Assessing placental maturity through histological and transcriptomic analyses in idiopathic spontaneous preterm birth 0.72
hNSCs siRNA NOVA2 0.69
Investigate A2M treatment on human prostate cancer and mouse liver 0.68
Investigate A2M treatment on human prostate cancer xenograft in mice 0.68
Gene expression profile of CRC-derived HILEC 0.64
Interleukin-1β induces mitochondrial DAMP production to activate STING-dependent innate immune programs 0.64
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 0.52
Functional astrocytes differentiated from hiPSCs 0.51
Patient-derived organoids (PDOs) model treatment response of metastatic gastrointestinal cancers. 0.49
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 0.47
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 0.43
RNA-Seq analysis of human colorectal cancer with liver metastasis 0.18
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 0.15
Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products 0.09
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 0.07
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 0.07
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 0.07
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.06
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.03
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.02
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 0.01


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation