Gene Query: EPN1

Dataset Description Geneva Score
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 59.48
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 40.78
Impact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST 33.45
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 32.43
HNRNPM-regulated splicing dependencies in prostate cancer 32.43
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 31.32
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 30.67
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 25.99
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 25.99
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 25.79
MOF acetyl transferase regulates transcription and respiration in mitochondria 24.5
miR941 overexpression experiment 23.7
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 23.24
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 23.22
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 22.39
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 22.22
DART-seq: an antibody-free method for global m6A detection 22.14
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 21.92
CD73 knockdown effect in pancreatic cancer cell lines 21.89
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 21.33
A role for ZNF598 in post-transcriptional gene regulation 20.99
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 20.71
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 20.68
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 19.67
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 19.03
RNA-seq and ChIP-seq analysis of BMI1 or RING1B-silenced prostate cancer cells C4-2 19.03
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 18.83
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 18.83
Active translatome profiling with RiboLace in MCF7 cells 18.36
The interplay between SOX4 and SMAD3 in the context of breast cancer 18.27
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 17.72
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 17.56
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 17.56
Genome wide expression change by RNF168 knocking down in NEC cells 17.07
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 16.97
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 16.83
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 16.78
TGF-β regulation of miRNA expression in pancreatic cancer 16.74
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing 16.48
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 16.45
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 16.0
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 16.0
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 15.65
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 15.61
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 15.54
Gene expression profile in breast cancer cells 15.24
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 15.24
Effect of CHKA knockdown on C4-2 cell transcriptome 15.23
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 15.07
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 14.79
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 14.79
Transcriptome analysis of SKI knock-out in HL60 cells 14.78
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 14.78
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 14.77
An integrative analysis of non-coding regulatory DNA variations associated with autism 14.77
FBXW7 modulates stress response by post-translational modification of HSF1 14.73
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 14.73
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 14.7
Studying the selectivity of a small molecule Synucleozid on transcriptome 14.66
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 14.66
Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing 14.55
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 14.48
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 14.48
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 14.46
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 14.46
Genome wide expression change by RNF168 knocking down in MCF-7 cells 14.39
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 14.25
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 13.78
RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer 13.41
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 13.38
High-throughput sequencing of pluripotent cells 13.24
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 12.5
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 (RNA-Seq) 12.5
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 12.45
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 12.29
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 12.24
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 12.24
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 12.24
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 12.2
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 12.16
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 12.04
ARID1A and ARID1B loss in HCT116 and TOV21G cells 11.83
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 11.71
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 11.61
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 11.58
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1 11.47
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 11.35
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 11.34
Transcriptomic analysis of the HOTAIR-regulated genes 11.34
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 11.29
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 11.2
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 11.18
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 11.09
11.04
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 11.02
K562 polyA RNA-Seq 11.0
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 10.88
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 10.85
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 10.7
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 10.66
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 10.64
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 10.64
The effect of Abl kinases on non-small cell carcinoma global transcriptome 10.62
High-Throughput Kinetic Analysis of Fractional Killing 10.6
Profiling of escape kinetics of viruses subjected to RNAi 10.57
Gene Expression Profiling of SPOP Knocked Down Cell 10.41
Lipid degradation promotes prostate cancer cell survival 10.29
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 10.26
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 10.21
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 10.17
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 9.95
HNF1 regulates critical functions of the human epididymis epithelium. [RNA-Seq] 9.94
HNF1 regulates critical functions of the human epididymis epithelium. 9.94
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 9.87
Global response to chemotherapy-induced apoptosis 9.87
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 9.84
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 9.76
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 9.76
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 9.67
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 9.65
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 9.64
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 9.64
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 9.59
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 9.59
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 9.53
Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient 9.5
RNA-Seq with DHT induction and/or GSK treatment at 24, 48 hrs and 2 weeks 9.5
FOXA1 Chromatin Binding is Regulated by LSD1-Mediated Demethylation 9.5
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 9.49
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 9.47
Impact of dieldrin on transcription in Jurkat T cells 9.38
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 9.32
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 9.26
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 9.26
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 9.26
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 9.26
The regulartory role of ZCCHC24 in splicing machinery 9.17
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 9.09
RNA-sequencing in irradiated and normal A549 cells. 9.03
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 9.0
Triple vectors expand AAV transfer capacity in the retina 8.99
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 8.99
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 8.99
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 8.9
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 8.88
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 8.86
Identification and Initial Functional Characterization of SENCR, a Long Non-Coding RNA Enriched in Human Vascular Cells 8.86
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 8.86
Expression profiling of MCF-7 cells with treatment of TCDD 8.86
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 8.8
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 8.73
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 8.72
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 8.71
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 8.7
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 8.7
Cleavage Factor Im as a key regulator of 3’ UTR length 8.69
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 8.69
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 8.68
DRB/GRO-Seq -/+ UV 8.66
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 8.65
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 8.65
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 8.62
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites 8.61
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites (RNA-seq) 8.61
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 8.58
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 8.58
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 8.57
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 8.55
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 8.52
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy 8.5
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 8.5
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 8.46
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 8.43
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 8.29
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 8.25
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 8.24
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 8.2
Pharmacologic inhibition of STAT5 in AML 8.18
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 8.12
Selective expression of long non-coding RNAs in a breast cancer cell progression model 8.12
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 8.11
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 8.1
Regulation of poly(A) tail and translation during the somatic cell cycle 8.07
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 7.96
The transcriptome and chromatin accessbility landscape of mammalian germline 7.95
Transcriptome profiling of Cryptosporidium parvum infected lung and intestinal organoids 7.92
LNCaP treated with iBET 7.84
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 7.79
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 7.79
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 7.74
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 7.73
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 7.73
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 7.73
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 7.59
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 7.56
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 7.54
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 7.51
RNA polymerase in pre-B-ALL cell lines 7.48
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 7.44
Transcriptome profiling of Caki2 cells re-expressing Polybromo-1 (PBRM1) 7.37
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 7.36
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 7.35
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 7.28
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 7.24
Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoids culture 7.22
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 7.16
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 7.15
Expression level comparison under dividing and quiescent states in human primary fibroblasts 7.12
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 7.1
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 7.1
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 7.05
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 7.01
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 6.93
Role of XRN2 ribonucleolytic activity in RNA metabolism 6.93
Region-specific Innate Antiviral Responses of the Human Epididymis 6.89
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 6.87
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 6.82
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 6.77
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 6.76
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 6.59
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 6.59
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 6.57
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 6.57
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 6.57
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 6.55
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 6.55
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 6.53
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 6.5
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 6.5
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 6.5
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 6.39
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 6.35
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 6.33
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 6.29
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 6.29
Aneuploidy triggers an immune response 6.22
Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines 6.15
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 6.14
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 6.12
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 6.12
Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1 6.12
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 6.1
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 5.93
Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted hearts 5.93
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 5.83
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 5.8
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 5.75
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 5.72
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 5.64
A High-Throughput Screen Identifies DYRK inhibitor ID-8 that Stimulates Human Kidney Tubular Proliferation 5.62
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 5.57
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 5.56
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 5.55
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 5.5
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 5.5
RNA seq_PDX2_SHP099 5.49
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 5.43
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 5.4
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 5.39
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 5.37
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 5.37
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 5.36
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 5.36
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 5.35
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 5.33
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 5.32
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 5.22
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 5.21
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 5.21
Tracking distinct RNA populations using efficient and reversible covalent chemistry 5.16
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 5.13
RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d) 5.13
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 5.09
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 5.08
Ectoderm specification of H1 human embryonic stem cells 5.06
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 5.04
RNA-Seq comparisons of gene expression profiles of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 5.02
ChIP-seq and RNA-Seq analyses of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 5.02
Identification of transcription start sites for human A549 cell line using ReCappable-seq 5.0
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 4.99
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 4.98
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 4.92
MARCKS and lnc-MARCKS act as inflammation regulators 4.88
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 4.83
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 4.83
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 4.83
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 4.83
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 4.83
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 4.75
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 4.7
Gene expression in PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition. 4.7
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 4.66
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 4.57
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 4.57
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 4.57
Searching for target genes of miR-508/509/506/514 in HCT116 cells 4.57
Functional role of CPPED1 in trophoblasts. 4.56
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 4.54
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 4.54
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 4.52
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 4.51
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 4.5
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 4.37
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 4.32
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 4.3
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 4.3
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 4.28
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 4.27
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 4.26
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 4.25
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 4.25
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 4.22
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 4.22
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 4.2
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 4.12
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 4.09
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  4.08
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 4.05
Genome-wide functional assessment of enhancer activities in the human genome 4.0
Gene expression analysis of human hepatocellular cancers 3.98
RNA-seq analysis of the human fetal kidney. 3.97
HEK293 TFAM Knockout Expression Study 3.94
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 3.93
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 3.93
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 3.85
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 3.8
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 3.77
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 3.74
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 3.7
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 3.66
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 3.64
Conservative alteration of chromosomal expression pattern across human solid tumor types 3.52
Molecular Mechanisms of Endothelial Hyperpermeability 3.52
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 3.5
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 3.47
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 3.43
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 3.43
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 3.43
Comparative transcriptome analysis reveals that ECM-Receptor Interaction contributes to the venous metastases of hepatocellular carcinoma 3.41
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 3.38
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 3.33
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 3.31
Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells. 3.3
Transcriptome analysis of kidney organoids 3.27
RNA-seq differential expression studies: more sequence, or more replication? 3.25
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 3.2
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 3.2
Total RNA-seq in ALL-SIL upon TLX1 knockdown 3.15
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 3.13
Identification of long noncoding RNAs in T-ALL cell lines 3.12
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 3.11
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 3.11
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 3.11
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 3.1
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 3.1
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 3.07
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 3.05
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 3.05
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 3.05
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 3.03
Paclitaxel plus Cirmtuzumab Achieves Greater Clearance of Patient-derived Xenografts By Targeting ROR1+ Breast Cancer Stem Cells 3.01
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 3.01
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 3.0
Transcriptomic profile of intestinal epithelial cells obtained from ileal endoscopic biopsies from newly-diagnosed, pediatric Crohn's disease patients and healthy controls. 2.99
Intrinsic Plasma Cell Differentiation Defects in BENTA Patient B cells 2.99
Effect of FGF13 depletion on the H460 cell line 2.96
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 2.92
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 2.92
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 2.9
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 2.87
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 2.86
KLF6-dependent transcription in renal cancer cells 2.8
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 2.75
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 2.67
Exogenous rescue of KLHL9 in SF210 cell line 2.66
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 2.62
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 2.52
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 2.49
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 2.47
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 2.38
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 2.33
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 2.28
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 2.23
The pioneer factor CEBPA modulates vitamin D signaling 2.18
Effects of transcription factor CEBPA knockdown on vitamin D target gene regulation in THP-1 cells 2.18
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 2.17
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 2.16
Functional significance of the HIV-1 Tat signature amino acid residues 2.1
Positively selected enhancer elements endow tumor cells with metastatic competence 2.05
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 2.03
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 2.03
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 1.98
Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells 1.94
Landscapes of gene translation in hepatocellular carcinoma tumors revealed by ribosome profiling 1.93
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 1.93
Expression charcaterization of an internal protocol developed to differentiate RPE cells 1.91
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 1.91
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 1.9
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 1.89
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 1.89
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 1.89
RNA-sequencing of healthy human skeletal myocytes 1.84
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 1.83
Interaction between mitoNEET and NAF-1 in cancer cells 1.82
Downregulation of LATS kinases alters p53 to promote cell migration 1.8
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 1.77
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 1.76
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 1.73
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 1.73
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 1.72
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 1.68
HEXIM1 is induced by DHODH inhibition to suppress melanoma 1.68
Enhancer activation during EGF response 1.67
Iron response of HepG2 cells 1.65
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 1.65
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 1.61
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 1.59
Myc activation coordinates gene transcription and protein translation responses 1.55
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 1.55
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 1.55
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 1.53
Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein 1.51
Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells 1.49
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 1.4
Genome-wide mapping of TEL-AML1 targets in acute leukemia 1.37
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 1.35
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 1.33
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 1.28
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 1.23
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 1.2
Interphase condensins regulate ligand-depedent enhancer activation 1.2
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 1.17
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 1.16
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 1.16
The bromodomain protein BRD4 regulates splicing during heat shock 1.13
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 1.12
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 1.09
Ribosome profiling upon inhibition of eIF4A 1.09
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 1.03
Androgen Receptor-regulated genes in prostate cancer cells 0.99
RNA-seq profiling identifies Androgen Receptor-regulated genes in prostate cancer cells 0.99
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 0.96
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 0.94
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 0.85
Rate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications 0.85
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 0.85
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.8
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.8
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 0.79
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 0.65
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 0.62
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 0.62
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 0.61
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.6
Aortic Valve Tissue: Stenosis vs. Sclerosis 0.56
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [BAV] 0.55
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 0.55
Transcriptomic Analysis Of circRNAs/miRNAs/mRNAs upon Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection 0.54
A MYC/GCN2/eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer 0.51
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 0.51
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.51
Human Tfh cell RNA bulk sequencing 0.48
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.48
SRSF1 role in cellular gene expression and splicing 0.47
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.43
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 0.42
Induced DNA demethylation, genome instability and transcription 0.42
Effect of BB608 on Gene Expression in HNSCC Cell Line 0.33
Regulation of hypoxia-inducible factor activity by ZMYND8 0.33
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 0.31
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 0.31
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 0.31
BACH2 in human plasma cell fate decision 0.31
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 0.3
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.29
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 0.26
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 0.21
A single-cell transcriptome atlas of the human pancreas 0.21
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.2
siRNA-mediated knockdown 0.19
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.18
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.17
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.17
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.16
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 0.14
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) in proliferation, quiescence, senescence and transformed states. 0.12
The role of m6A/m-RNA methylation in stress response regulation 0.11
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.11
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 0.08
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 0.08
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.08
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 0.07
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 0.05
Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles 0.05
MHC Transcriptomic landscape at haplotype-specific resolution 0.05
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 0.04
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.04
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.01
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 0.01
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.01


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