Gene Query: EZH2

Dataset Description Geneva Score
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 748.48
Statins modulate endothelial transcriptional profile by inhibiting EZH2 167.22
The transcriptome effect of overexpressing EZH2 in MCF7 94.01
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 70.08
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 48.56
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 46.98
Effect of Hotair overexpression in human breast cancer cell lines 45.72
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 45.48
Comparative Transcriptomics of Triple Negative Breast Cancer Stem Cells and Differentiated Tumor Cells Identifies Teneurin-4 as a Potential Therapeutic Target 44.4
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 43.64
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 43.64
Transcriptional profiles of normal human mature B cells 41.97
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 40.46
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 40.38
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 33.82
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 33.82
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 33.06
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 31.34
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 30.69
Transcriptome analysis of BAP1 knockout and restoration 30.69
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 29.16
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 27.72
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 27.71
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 27.44
Recovery and analysis of nascent RNA 26.75
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 26.75
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 26.44
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 24.97
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 24.93
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 24.65
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 24.56
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 24.56
Selective suppression of endothelial cytokine production by progesterone receptor [RNA-seq] 24.35
Selective suppression of endothelial cytokine production by progesterone receptor 24.35
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 23.46
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 23.23
Genome wide expression change by RNF168 knocking down in MCF-7 cells 22.61
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 22.41
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 21.54
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 21.54
Knockdown of ADNP in HCT116 colon cancer cells 21.16
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 21.06
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 20.94
RNA-seq of resting and activated CD4+ T cells +-JQ1 20.83
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 20.5
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 20.46
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 20.46
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 20.42
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 20.31
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 20.07
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 20.07
Transcription control by the ENL YEATS domain in acute leukemia 20.07
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 19.7
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 19.68
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 19.34
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 19.34
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 19.26
Resistance to BET inhibitor leads to new therapeutic vulnerabilities in castration resistant prostate cancer 19.21
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 18.97
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 18.97
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 18.82
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 18.59
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 18.5
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 18.21
Human HAP1 cells before and after nutrient deprivation 18.21
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 18.2
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 18.02
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 17.9
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 17.75
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 17.29
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 17.24
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 16.91
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 16.82
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 16.61
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 16.28
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 16.26
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 16.06
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 15.78
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 15.53
Spliceosomal disruption of the non-canonical BAF complex in cancer 15.24
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 15.21
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 15.19
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 15.19
Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation 15.17
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 15.17
HNRNPM-regulated splicing dependencies in prostate cancer 15.17
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 15.1
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 15.01
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 14.9
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 14.74
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 14.72
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 14.51
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 14.43
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 14.43
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 14.32
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 14.23
Transcriptome analysis of U87 cells upon LINC00152 knockdown 14.2
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 14.16
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 14.08
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 14.01
Identification of global regulators of T-helper cell lineage specification 14.0
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 14.0
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 13.98
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 13.95
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 13.87
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 13.82
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 13.76
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 13.75
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 13.63
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 13.6
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 13.53
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 13.53
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 13.48
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 13.47
In situ CAPTURE of chromatin interactions by biotinylated dCas9 13.44
RNA-seq transcriptonal profiling in human K562 cells with or without dCas9 and sgRNAs 13.44
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 13.4
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 13.4
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 13.34
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 13.34
Genome wide expression change in LCC2 and MCF-7 cells 13.27
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 13.22
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 13.21
Retinoic acid suppresses MYB in adenoid cystic carcinoma 13.07
Retinoic acid suppresses MYB in adenoid cystic carcinoma [RNA-seq] 13.07
Landscape of H3K4me3 in human CD19 cells 12.82
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 12.77
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 12.76
SRSF2 mutations impair hematopoiesis and alter exon recognition 12.69
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 12.6
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 12.45
Regulation of protein translation during mitosis 12.37
Universal alternative splicing of noncoding exons 12.31
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 12.31
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 12.31
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 12.28
Inhibition of TNBC metastasis by Gpx1 12.27
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 12.24
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 12.22
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 12.22
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 12.21
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 12.13
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 12.08
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 12.05
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 12.0
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 11.99
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 11.99
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 11.91
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 11.91
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 11.88
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 11.83
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 11.83
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 11.8
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 11.77
DIGIT regulates endoderm differentiation of human embryonic stem cells 11.68
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 11.57
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 11.55
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 11.54
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 11.52
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 11.49
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 11.4
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 11.4
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 11.37
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 11.37
Toxoplasma gondii infection of human retinal pigment epithelial cells 11.32
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 11.26
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 11.07
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 11.07
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 11.07
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 11.07
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons 11.05
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 10.94
Targeting EZH2 in MYCN-amplified Neuroblastoma 10.92
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 10.92
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 10.89
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 10.8
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 10.8
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 10.78
Bone marrow derived human B cells [normal proB] 10.73
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 10.72
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 10.7
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 10.7
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 10.69
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 10.66
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 10.66
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 10.65
Generation of KRAS signatures using immortalized isogenic lung cells. 10.63
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 10.57
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 10.55
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 10.53
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 10.53
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 10.51
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 10.51
DJ-1 is dispensable for human stem cell homeostasis 10.48
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 10.46
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 10.45
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 10.45
Genome-wide transcriptional response to random aneuploidy in human cells 10.44
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 10.43
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 10.38
Noncoding regions are the main source of targetable tumor-specific antigens 10.36
FBXW7 modulates stress response by post-translational modification of HSF1 10.34
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 10.34
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 10.3
Neurofibroma 10.29
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 10.29
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 10.22
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 10.19
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 10.13
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 10.07
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 10.03
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 9.99
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 9.99
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 9.99
Genome-wide chromatin analysis of Ewing sarcoma 9.99
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 9.9
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 9.9
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 9.88
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 9.88
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 9.86
Gene expression analysis of immortalized human liver progenitor-like cells in culture 9.85
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 9.84
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 9.83
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 9.82
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 9.82
A single cell reference map for human blood and tissue T cell activation 9.81
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 9.8
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 9.75
Effect of from Human Umbilical Vein Endothelial Cells 9.72
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 9.69
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours [RNA-seq] 9.65
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours 9.65
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 9.65
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 9.62
RIG-I and MDA5 fRIP during KSHV lytic reactivation 9.59
A code of mono-phosphorylation modulates the function of RB. 9.59
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 9.55
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 9.5
A map of gene expression in neutrophil-like cell lines 9.47
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 9.45
Transcriptome-wide identification of CELF2 functional targets in T cells 9.42
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 9.4
The role of FAM46C in myeloma cells [sequencing] 9.39
The role of FAM46C in myeloma cells 9.39
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 9.37
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 9.37
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 9.36
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 9.34
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 9.33
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 9.33
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 9.33
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 9.3
Overexpression and knockdown experiment for circCSNK1G3 9.29
Transcriptomes of human monocytes after ex vivo exposure to uric acid 9.28
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 9.22
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 9.22
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 9.2
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 9.16
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 9.14
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 9.12
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 9.12
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 9.04
Lineage specific differentiation is influenced by state of human pluripotency 9.04
Studying the selectivity of a small molecule Synucleozid on transcriptome 9.03
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 9.01
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 8.99
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 8.97
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 8.96
Co-transcriptional loading of RNA export factors shapes the human transcriptome 8.96
RNAseq of HEK293 cells after Chtop knockdown 8.96
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 8.92
mRNA-Seq profiling of human developing kidney 8.92
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 8.87
Whole-transcriptome profilings between a pair of HCA7-derived KRAS-wildtype cetuximab sensitive and resistant colon cancer cells from 3D culture 8.87
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 8.86
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 8.86
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 8.84
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 8.82
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 8.81
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 8.77
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 8.75
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 8.74
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 8.71
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 8.7
PTHrP overexpression in MCF7 cells 8.7
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 8.67
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 8.67
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 8.66
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 8.63
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 8.58
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 8.57
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 8.54
Biological effect of chronic mistranslation in mammalian cells 8.54
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 8.52
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 8.52
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 8.5
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 8.47
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing 8.4
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing [RNA-Seq] 8.4
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 8.38
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 8.38
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 8.35
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 8.29
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 8.27
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 8.26
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 8.26
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 8.23
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 8.23
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 8.19
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 8.17
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 8.16
Widespread intronic polyadenylation diversifies immune cell transcriptomes 8.15
Regionally specified human pluripotent stem cell-derived astrocytes 8.09
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 8.09
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 8.09
Crizotinib v. DMSO in SW480 cells 7.94
Transcriptomic insights into human decidual and peripheral blood CD8 T cells 7.9
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 7.9
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 7.7
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 7.69
HEK293 Heat-shock experiment 7.67
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 7.66
Mapping interactions for the TNIP2 hub protein 7.65
Downregulation of DDX5/DDX17 and REST 7.62
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 7.56
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 7.56
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 7.54
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 7.54
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 7.54
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 7.47
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 7.42
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 7.42
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 7.37
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 7.37
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 7.34
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 7.19
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 7.14
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 7.03
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 6.97
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 6.87
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 6.87
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 6.83
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 6.76
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 6.69
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 6.67
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 6.64
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 6.63
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 6.63
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 6.5
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 6.49
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 6.48
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 6.48
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 6.35
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 6.27
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 6.17
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 6.16
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 6.1
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 5.98
Downregulation of LATS kinases alters p53 to promote cell migration 5.98
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 5.95
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 5.94
Targeted enhancer activation by a subunit of the integrator complex 5.92
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 5.89
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 5.88
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 5.88
Identification of Sin3B regulated genes during quiescence 5.85
Next Generation Sequencing of human SMA and healthy control Motor Neurons 5.63
Characterization of human ILC2 subsets 5.62
Targeting MTHFD2 in Acute Myeloid Leukemia 5.56
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 5.54
Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression 5.46
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 5.44
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 5.44
Human cells contain natural double-stranded RNAs with potential regulatory capacity 5.43
Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1 5.43
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 5.38
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 5.36
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 5.36
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 5.33
K562 polyA RNA-Seq 5.22
Hypoxic transcriptome of SQ20B human head and neck cancer cells 5.13
scRNASeq analysis of cycling cardiomyocytes 5.07
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 5.07
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 4.99
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001 4.96
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 4.95
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 4.94
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 4.94
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 4.9
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 4.8
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 4.8
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 4.78
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 4.78
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 4.76
Identification of HOXB13 target genes responsive to BET inhibitors 4.75
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 4.65
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 4.57
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 4.48
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 4.3
Function and hormonal regulation of GATA3 in human first trimester placentation 4.28
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 4.28
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 4.25
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 4.25
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 4.23
Comparative Analysis of Cas9 Activators Across Multiple Species 4.14
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 4.08
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 4.07
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 4.04
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 4.02
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 3.99
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 3.99
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.92
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 3.92
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 3.91
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 3.86
Human Treg NaCl stimulation 3.84
Human Treg IFNg/IL-10 subpopulations 3.72
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 3.68
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 3.67
Rate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications 3.6
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 3.53
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 3.35
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 3.3
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 3.3
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 3.24
Primate-specific gene TMEM14B promotes cortical expansion and folding 2.99
Identification of renal resident macrophages across species [C1] 2.89
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 2.88
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 2.85
SF3B1 Degron knockdown RNA-seq 2.84
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 2.82
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 2.73
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 2.73
Transcriptional profiling of CD45RO+CD57+CD4+ T cells 2.71
NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells 2.7
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 2.65
TAF1 is critical for AE driven leukemogenesis 2.65
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 2.63
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 2.62
RNA-Seq in PWS iPSC-derived neurons 2.56
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 2.47
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 2.35
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 2.35
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 2.33
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 2.28
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 2.16
Gene expression regulated by CSA and CSB in neuroblastoma cell line 2.08
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 2.07
Human Treg IL-12 stimulation 1.99
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 1.96
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 1.96
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.92
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.92
Identification of long noncoding RNAs in T-ALL cell lines 1.72
Entrectinib Resistance in a Neuroblastoma Xenograft Model 1.7
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 1.68
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 1.64
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 1.55
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 1.49
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 1.41
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 1.37
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 1.28
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 1.22
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 1.18
Clinker: visualizing fusion genes detected in RNA-seq data 1.15
Proliferation-correlated expression 1.14
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 1.1
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 1.1
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 1.02
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 1.02
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 1.0
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.95
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.85
Specific molecular signatures underlie response to decitabine in CMML 0.85
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.84
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 0.78
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 0.78
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 0.75
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 0.75
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 0.73
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.71
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.7
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 0.65
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 0.63
SNHG5 siRNA knock down in HCT116 cells 0.58
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.49
Modulation of nonsense-mediated decay by rapamycin 0.48
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.47
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 0.41
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 0.38
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 0.38
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 0.34
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 0.13
Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells 0.1
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 0.1
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 0.03
ADAR1-editing of cellular and measles virus-derived duplex RNA 0.03
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.03
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.03
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.02


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