Gene Query: FANCI

Dataset Description Geneva Score
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 102.9
Genome-wide transcriptional response to random aneuploidy in human cells 101.58
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 88.76
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 88.76
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 87.3
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 87.03
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 87.03
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 74.91
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 70.76
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 66.76
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 59.29
The regulartory role of ZCCHC24 in splicing machinery 55.41
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 54.55
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 52.69
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 49.68
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 49.25
Transcriptional profiles of normal human mature B cells 48.19
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 47.3
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 46.86
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 46.09
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 45.13
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 44.55
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 44.12
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 44.12
Paxillin regulates genomic networks in prostate cancer [LNCaP] 43.45
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 43.1
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 42.34
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 42.34
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 42.31
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 41.7
RNA-sequencing in irradiated and normal A549 cells. 41.26
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 40.59
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 40.55
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 40.29
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 39.93
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 39.78
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 37.91
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 37.22
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 37.13
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 36.76
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 36.31
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 35.85
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 35.85
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 35.85
Effect of CHKA knockdown on C4-2 cell transcriptome 35.56
Effect of Influenza virus infection on lncRNA expression in A549 cells 35.54
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 34.4
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 33.99
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 33.61
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 33.61
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 33.56
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 33.24
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 32.96
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 32.27
Role for citron kinase in prostate cancer growth 32.2
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 31.26
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 31.23
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 31.09
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 31.06
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 30.62
Transcriptome analysis of VCaP xenografts resistant to dual therapy with abiraterone and enzalutamide 30.46
The landscape of alternative splicing in aggressive prostate cancers 30.28
Transcriptome analysis of U87 cells upon LINC00152 knockdown 30.2
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 30.18
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 30.18
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 30.01
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 29.33
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 29.31
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 29.28
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 29.21
IRF2 is a master regulator of human keratinocyte stem cell fate 29.21
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 29.07
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 29.05
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 28.76
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 28.75
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells 28.73
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 28.38
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 28.38
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 28.33
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 28.25
RNA-seq of resting and activated CD4+ T cells +-JQ1 28.1
Identification of global regulators of T-helper cell lineage specification 27.85
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 27.85
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 27.7
Genome wide expression change by RNF168 knocking down in MCF-7 cells 27.68
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 27.55
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 27.54
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 27.54
Landscape of H3K4me3 in human CD19 cells 27.39
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 27.2
MCF10A H-Ras RNA-Seq 26.98
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 26.29
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 26.03
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 26.03
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 25.95
Appropriately Differentiated ARPE-19 Cells Regain a Native Phenotype and Similar Gene Expression Profile 25.82
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 25.69
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 25.64
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 25.42
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 25.23
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 25.06
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 24.79
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 24.69
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 24.64
Tyrosine Kinase Inhibitor Cardiotoxicity 24.62
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 24.62
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 24.53
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 24.47
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 24.47
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 24.41
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 24.41
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 24.33
MYCi361 regulates MYC target genes 24.3
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 24.3
Identifying the molecular mode of action of itraconazole in colorectal cancer 24.25
Transcriptome analysis of human airway epithelium infected by Human Bocavirus 1 24.21
Transcriptome profiling identified a 3-lncRNA regulatory network in transthyretin against glucose induced hRECs dysfunction 23.63
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 23.5
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 23.35
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 23.29
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 23.08
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 22.75
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 22.63
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 22.57
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 22.52
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 22.39
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 22.36
Gene expression analysis of immortalized human liver progenitor-like cells in culture 22.28
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 22.09
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 22.09
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 21.92
RNAseq of HEK293 cells after Chtop knockdown 21.6
Co-transcriptional loading of RNA export factors shapes the human transcriptome 21.6
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 21.48
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 21.18
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 21.18
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 20.95
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 20.93
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 20.8
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 20.75
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 20.71
3’ Uridylation Expands miRNA Target Repertoire 20.61
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 20.57
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 20.46
Transcriptome analysis of Zika infected neural stem cells 20.28
Zika infected neural stem cells 20.28
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 20.24
Genes significantly down or Up-regulated upon RNF219 knockdown 20.14
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 20.11
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 20.11
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 20.03
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 20.0
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 19.97
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 19.91
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 19.67
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 19.53
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 19.38
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 19.24
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 19.09
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 19.03
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 18.83
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 18.62
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 18.62
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 18.56
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 18.45
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 18.33
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 18.25
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 18.21
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 18.2
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 18.2
Transcriptional responses of human insulinoma cells to acute cytokine exposure 18.15
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 18.14
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 18.12
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 18.12
A code of mono-phosphorylation modulates the function of RB. 18.11
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 18.07
LncRNA-GAS5 negative regulation of YAP-target genes expression 17.95
An RNA-centric dissection of host complexes controlling flavivirus infection 17.95
An RNA-centric dissection of host complexes controlling flavivirus infection [RNA-Seq] 17.95
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 17.91
Differentially expressed vascular development genes for iPSC-ECs from CDI 17.91
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 17.82
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 17.77
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 17.71
Neurofibroma 17.71
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 17.66
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 17.65
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 17.62
A Unique Epigenomic Landscape Defines Human Erythropoiesis 17.62
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 17.61
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 17.6
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 17.6
Genome-wide chromatin analysis of Ewing sarcoma 17.5
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 17.5
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 17.42
STRIPAK directs PP2A activity to promote oncogenic transformation 17.35
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 17.3
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 17.27
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 17.17
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 17.17
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 17.02
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 16.94
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 16.89
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 16.84
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 16.83
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 16.83
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 16.81
Widespread intronic polyadenylation diversifies immune cell transcriptomes 16.8
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 16.75
RNA-seq differential expression studies: more sequence, or more replication? 16.73
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 16.71
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 16.7
Transcriptome of U251 cells overexpression complement component 7 16.62
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 16.59
Evolving Spindlin1 Small Molecule Inhibitors Using Protein Microarrays 16.55
Overexpression and knockdown experiment for circCSNK1G3 16.49
Identification of HOXB13 target genes responsive to BET inhibitors 16.48
Impact of HypERrlnc Knockdown on the human pericyte transcriptome 16.4
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 16.26
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 16.09
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 16.07
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 16.05
Gene expression changes caused by KRAS in MCF-10A 15.97
Transcription control by the ENL YEATS domain in acute leukemia 15.96
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 15.96
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 15.93
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 15.85
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 15.84
Triple vectors expand AAV transfer capacity in the retina 15.84
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 15.82
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 15.82
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 15.8
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 15.76
Pharmacologic inhibition of STAT5 in AML 15.76
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 15.64
Unique features and clinical importance of acute alloreactive immune responses 15.64
Expression level comparison under dividing and quiescent states in human primary fibroblasts 15.63
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 15.62
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 15.55
Induced DNA demethylation, genome instability and transcription 15.55
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 15.53
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 15.43
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 15.4
Role of XRN2 ribonucleolytic activity in RNA metabolism 15.38
Generation of trichogenic adipose-derived stem cells by expression of three factors 15.34
Trans-differentiation of human adult peripheral blood T cells into neurons 15.31
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 15.29
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 15.26
Determination of tRNA aminoacylation levels by high throughput sequencing 15.26
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 15.22
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 15.22
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 15.17
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 15.11
Profiling of escape kinetics of viruses subjected to RNAi 15.06
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 15.04
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 15.03
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 14.99
RNA-seq of YB5 cells treated with Proscillaridin A 14.96
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 14.93
Knockdown of ADNP in HCT116 colon cancer cells 14.77
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 14.7
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 14.66
Identification of transcription start sites for human A549 cell line using ReCappable-seq 14.65
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 14.49
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 14.47
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 14.46
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 14.4
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 14.39
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 14.27
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 14.26
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 14.24
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 14.16
AR-independent prostate cancer is sustained through FGF signaling 14.15
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 14.1
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 14.09
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 14.07
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 14.02
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 14.01
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 14.01
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype 14.01
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 14.0
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 13.98
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 13.94
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 13.94
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 13.86
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 13.84
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 13.83
Ro60-knockout cells 13.66
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 13.46
RNA-seq analysis of SLIRP knockdown with 1nM DHT in LNCaP cells 13.42
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 13.41
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 13.4
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 13.22
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 13.22
FOXP2's impact on the primate transcriptome 13.17
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 13.14
Transcriptome analysis of BAP1 knockout and restoration 13.07
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 13.07
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours [RNA-seq] 13.06
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours 13.06
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 13.05
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  12.96
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 12.83
Transcriptional responses of melanoma cells to BRAF inhibition 12.82
Bone marrow derived human B cells [normal proB] 12.71
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 12.67
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 12.66
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses 12.64
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 12.57
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 12.48
A map of gene expression in neutrophil-like cell lines 12.46
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 12.36
Human cell line and subcutaneous tumor 12.32
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 12.28
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 12.22
MicroRNA targetome analysis during HCMV infection 12.2
Integrin signaling regulates YAP/TAZ to control skin homeostasis 12.02
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 11.9
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 11.88
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 11.88
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 11.86
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 11.74
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 11.73
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 11.73
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 11.58
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 11.45
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 11.43
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 11.37
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 11.37
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 11.36
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 11.35
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 11.34
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 11.33
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 11.31
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 11.29
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 11.2
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 11.16
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 11.16
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 10.96
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 10.7
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 10.56
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 10.47
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 10.47
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 10.27
HNRNPM-regulated splicing dependencies in prostate cancer 10.27
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 10.24
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 10.24
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 10.19
Transcriptome-wide identification of CELF2 functional targets in T cells 10.09
A549 cell transcriptome responses to infection with H7N9 influenza virus 10.06
Human cells contain natural double-stranded RNAs with potential regulatory capacity 9.93
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 9.92
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 9.82
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 9.82
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 9.81
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 9.77
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 9.77
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 9.71
Identification of Sin3B regulated genes during quiescence 9.7
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 9.45
Differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 9.41
mRNA differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 9.41
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 9.27
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 9.16
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 9.1
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 8.94
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 8.73
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 8.71
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 8.71
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 8.52
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 8.52
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 8.4
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 8.38
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 8.35
Differential Gene Expression between MCF10A and MCF7 cells 8.34
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 8.18
TAF1 is critical for AE driven leukemogenesis 8.09
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 8.09
High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872 8.02
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 8.0
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 7.94
RNAseq of cell lines with knocked in ESR1 mutations 7.86
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 7.78
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 7.47
HBEC-shp53-PCHD7 7.44
The Genetic Landscape of Diamond-Blackfan Anemia 7.4
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 6.97
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 6.88
FGF2 regulation of gene expression in stable inducible Neurons 6.68
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 6.46
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 6.35
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 6.27
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 6.27
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 6.25
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 6.14
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 6.14
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 6.06
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 6.05
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 5.91
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 5.78
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 5.78
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 5.78
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 5.61
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 5.38
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 5.32
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 5.14
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 5.12
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 5.09
Effect of from Human Umbilical Vein Endothelial Cells 4.96
Entrectinib Resistance in a Neuroblastoma Xenograft Model 4.8
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 4.77
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 4.72
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 4.5
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 4.47
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 4.44
Comparative Analysis of Cas9 Activators Across Multiple Species 4.36
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 4.33
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 4.27
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 4.27
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 4.25
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 4.24
Loss of CREBBP results in gene expression repression in lymphoma cells 4.24
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 4.23
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 4.18
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 4.18
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 4.05
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 4.02
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 4.02
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 3.96
The cytokine environment influence on human skin-derived T cells 3.96
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 3.9
CDK12 mediated transcriptional regulation in U2OS cells 3.9
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 3.89
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 3.89
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 3.87
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 3.84
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 3.77
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 3.76
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 3.71
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 3.63
Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates 3.58
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 3.55
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 3.51
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 3.46
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 3.41
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 3.3
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  3.28
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 3.21
Gene expression profile of multiple myeloma cell lines treated with CB-5083 3.15
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 3.12
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 3.12
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 3.05
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 2.99
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 2.93
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 2.91
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 2.69
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 2.55
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 2.53
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 2.45
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 2.43
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 2.31
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 2.31
Clinker: visualizing fusion genes detected in RNA-seq data 2.24
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 2.18
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 2.15
6mer seed toxicity in tumour suppressive microRNAs 2.07
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 1.96
RNA sequencing of human pancreatic cancer cell lines 1.92
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 1.92
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 1.86
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 1.86
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 1.86
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.85
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 1.75
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 1.66
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 1.66
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 1.64
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 1.44
Preclinical model of obesity and ER-positive breast cancer 1.39
High-resolution comparative analysis of great ape genomes 1.26
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 1.15
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 1.06
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.05
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 1.05
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 0.96
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.95
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.93
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.92
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 0.86
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.77
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.72
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 0.71
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 0.53
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.43
Zika virus infection reprograms global transcription of host cells to allow sustained infection 0.4
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.25
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.25
Modulation of nonsense-mediated decay by rapamycin 0.11
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 0.06
Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells 0.02


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation