Gene Query: FARP1

Dataset Description Geneva Score
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 92.91
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 92.63
Gene Expression Profiling of SPOP Knocked Down Cell 87.06
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 48.08
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 47.83
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 47.69
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 42.54
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 40.42
Differential gene expressions in the heart of hypertrophic cardiomyopathy patients 40.42
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 39.65
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 38.77
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 38.0
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 37.72
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 37.48
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 34.96
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 34.03
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 33.86
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 32.53
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 30.29
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 29.49
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 28.9
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 28.51
Global expression profiles in cardiac progenitor cells generated by ISX-9 28.51
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 28.03
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 25.98
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 25.44
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 24.69
Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a Colorectal Cancer Patient-derived Tumor Explant Model 23.99
ARID1A regulates condensin II distribution and chromosomal partition 23.15
ARID1A regulates condensin II distribution and chromosomal partition [RNA-seq] 23.15
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 23.09
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 22.79
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 22.51
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 21.73
Nucleoporin-mediated regulation of cell identity genes 21.64
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 21.58
Primate transcript and protein expression levels evolve under compensatory selection pressures 21.33
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 21.08
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 21.08
Comparing effects of perfusion and hydrostatic pressure on human chondrocytes using gene profiles 21.0
Human embryonic stem cells in E8 and AKIT culture medium 20.95
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 20.95
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 20.94
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 20.93
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 20.86
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 20.59
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 20.43
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 20.4
Role of microRNAs in the interaction between Salmonella and the host cell 20.22
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization [RNA-Seq] 20.21
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization 20.21
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 19.41
The effect of PPARG inhibition on human angiomyolipoma cells 19.24
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 19.19
SOX11 knockdown in B-ALL cell lines 18.78
HNRNPL and its RNA Targets in Prostate Cancer 18.7
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 18.7
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 18.12
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 18.12
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 17.83
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 17.82
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 17.82
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 17.67
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 17.67
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 17.67
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 17.43
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 17.41
Role of XRN2 ribonucleolytic activity in RNA metabolism 17.41
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 17.32
Transcriptome of U251 cells overexpression complement component 7 17.24
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 17.2
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 17.06
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 17.02
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 17.02
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 16.62
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 16.61
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 16.61
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 16.58
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 16.51
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 16.49
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 16.39
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 16.36
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 16.34
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 16.13
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 16.04
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 15.88
Co-regulation of splicing by Rbfox1 and hnRNP M 15.66
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 15.66
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 15.63
High-Throughput Kinetic Analysis of Fractional Killing 15.6
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 15.58
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 15.49
RNA-seq of cancer-associated fibroblasts (CAF) treated with PBS or extracellular vesicles (EV) from MCF10A or MDA-MB-231 cells 15.47
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_1A_PI3K_RNA-seq] 15.46
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 15.43
Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression 15.4
Global gene expression profiling from LeuCAG3'tsRNA depleted- HeLa and HCT-116 cell lines through 50 base pair paired-end RNA-seq 15.29
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 15.21
Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 15.01
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 14.95
AMPK signaling for naïve pluripotency [Hs] 14.94
AMPK signaling for naïve pluripotency 14.94
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 14.89
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 14.79
Genetic disruption of COX-1 inhibits multiple oncogenic pathways 14.75
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 14.69
Global gene expression profile of dasatinib-resistant RCH-ACV cells 14.63
Transcriptome analysis of virus infected tissues 14.63
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 14.62
Lineage specific differentiation is influenced by state of human pluripotency 14.62
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 14.59
A novel target of EZH1/2 for treatment of mantle cell lymphoma 14.56
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 14.48
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis 14.47
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 14.44
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 14.43
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 14.23
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 14.21
MEIS1 regulates hematopoiesis in hPSCs 14.16
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 14.14
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 14.05
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 14.05
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 14.0
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 13.95
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 13.95
Expression profiling of etoposide-induced senescent cells 13.8
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 13.77
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 13.61
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 13.61
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 13.51
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 13.28
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 13.28
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 13.25
NKX2.2 13.25
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 13.14
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 13.09
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 13.09
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 13.08
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 13.08
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 13.0
Differential expression of genes in AD169-infected MRC5. 12.9
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 12.89
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 12.86
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 12.86
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 12.86
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 12.86
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 12.84
Universal alternative splicing of noncoding exons 12.82
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 12.82
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 12.8
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 12.77
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 12.73
Gene profiling of human adult and pediatric liver cancer cells 12.64
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 12.61
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 12.56
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 12.49
Genome-wide identification of cancer-specific alternative splicing in circRNA 12.39
RNA-sequencing of human peripheral blood mononuclear cells (PB MNCs) and induced neural progenitor cells derived from PB MNCs 12.35
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 12.33
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 12.24
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 12.24
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 12.22
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 12.21
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 12.2
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 12.2
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 12.13
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 12.03
Modeling Familial Cancer with iPSC Approaches 11.99
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 11.98
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 11.98
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 11.89
Gene expression profiling of KSHV-infected periodontal ligament cells 11.86
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 11.8
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 11.8
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 11.77
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 11.77
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 11.6
SRSF2 mutations impair hematopoiesis and alter exon recognition 11.55
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 11.54
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 11.53
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 11.5
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 11.46
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 11.44
MOF acetyl transferase regulates transcription and respiration in mitochondria 11.37
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 11.35
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 11.33
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 11.33
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 11.33
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 11.32
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  11.21
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 11.14
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 11.13
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 11.11
Single-nucleotide-resolution mapping of HBV promoters using CAGE 11.01
LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression 10.91
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 10.89
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 10.83
RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes 10.76
MicroRNA targetome analysis during HCMV infection 10.7
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 10.66
Nrf2 regulated genes in A549 cells 10.65
Identification of Nrf2 regulated genes by RNA sequencing 10.65
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 10.59
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 10.59
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [GRO-seq II] 10.57
Transcriptomic profiling of HeLa cells infected with Salmonella Typhimurium 10.57
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 10.56
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 10.56
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 10.55
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. 10.55
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 10.4
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 10.37
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 10.36
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 10.36
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 10.34
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 10.32
Epigenomic landscape during organ formation in human early embryos 10.32
Gene expression changes upon drug withdrawal (Mel888 cell line) 10.31
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 10.3
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 10.24
The role of m6A/m-RNA methylation in stress response regulation 10.24
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 10.22
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 10.21
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 10.19
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 10.19
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 10.16
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 10.16
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 10.16
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 10.14
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 10.14
circRNA-sequencing 10.14
RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines 9.96
Identification of Atrial Fibrillation associated genes and functional non-coding variants 9.95
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 9.94
Impact of HypERrlnc Knockdown on the human pericyte transcriptome 9.83
Transcriptional profiling of microglia; current state of the art and future perspectives 9.72
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 9.69
Modulation of ESRP2 and MBNL2 in normal kidney and clear cell renal cell carcinoma cell lines for analysis of stability programs 9.68
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 9.64
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 9.64
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 9.61
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 9.6
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 9.6
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 9.58
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 9.56
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 9.54
RNA-seq analysis of BAP1-depleted uveal melanoma cells 9.53
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 9.51
RNA-seq and ChIP-seq analysis of BMI1 or RING1B-silenced prostate cancer cells C4-2 9.49
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 9.48
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 9.45
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 9.44
Transcriptome analysis revealed impaired cAMP responsiveness in PHF21A-deficient human cells 9.43
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 9.3
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 9.29
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 9.29
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 9.22
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 9.18
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 9.17
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 9.13
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 9.13
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 9.13
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 9.09
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 9.07
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 9.07
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 9.06
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 9.06
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2) 9.03
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 9.03
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 9.01
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 8.97
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 8.94
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 8.92
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 8.79
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 8.71
Patient-derived luminal breast cancer xenografts with progestins 8.71
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 8.7
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 8.7
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  8.7
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 8.66
LncRNA-GAS5 negative regulation of YAP-target genes expression 8.66
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 8.66
IRF1 regulates IFN dependent and independent gene expression 8.63
mRNA sequencing of oropharyngeal cancer cell lines 8.55
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 8.5
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 8.49
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 8.43
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 8.31
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 8.31
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 8.3
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 8.19
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 8.17
The Genomic Landscape of Atypical Fibroxanthoma 8.13
RNA-sequencing in irradiated and normal A549 cells. 8.09
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 8.03
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 8.0
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 7.97
Transcriptome analysis of human airway epithelium infected by Human Bocavirus 1 7.85
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 7.81
IRF2 is a master regulator of human keratinocyte stem cell fate 7.81
RNA-seq of naive and primed ES cells 7.64
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 7.62
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 7.61
Allelic expression mapping across cell lineages reveal repressor disruption among disease SNPs 7.58
Targeting EZH2 in MYCN-amplified Neuroblastoma 7.54
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 7.54
Human interleukin-4 treated regulatory macrophages promote epithelial wound healing and reduce colitis in an mouse model 7.53
Statins modulate endothelial transcriptional profile by inhibiting EZH2 7.5
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 7.49
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 7.49
Gene expression changes in HSV-1 infected HeLa cells with knockdown of B2M 7.46
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 7.31
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 7.27
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 7.27
Unbiased evaluation of cell-free amniotic fluid transcriptome of term and preterm infants to detect fetal maturity 7.23
CD95/Fas ligand mRNA is toxic to cells 7.22
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 7.22
A Basal Stem Cell Signature Identifies Aggressive Prostate Cancer Phenotypes 7.21
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 7.19
Expression profiling of MCF-7 cells with treatment of TCDD 7.19
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 7.17
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 7.17
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 7.15
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 7.11
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 7.11
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 7.02
SETBP1-WT and SETBP1-G870S epigenetic landscapes 7.02
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia 6.93
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 6.88
Divergent expression and metabolic functions of human glucuronosyltransferases through alternative splicing 6.84
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 6.8
Molecular Biomarkers Screened by Next-generation RNA Sequencing for non-sentinel lymph node status predicting in breast cancer patients with metastatic sentinel lymph node 6.63
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 6.57
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 6.57
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 6.53
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 6.48
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 6.48
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 6.44
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 6.43
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 6.4
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 6.4
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with pancreatic carcinoma 6.38
A code of mono-phosphorylation modulates the function of RB. 6.31
Identification of differentially expressed genes between senescence and senescence bypass cells 6.29
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 6.12
Induced DNA demethylation, genome instability and transcription 6.12
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 6.09
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 6.08
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 6.06
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 6.06
Genome-wide discovery of human splicing branchpoints 6.05
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 5.93
Recovery and analysis of nascent RNA 5.93
Histone Demethylases KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging through condensin-mediated heterochromatin organization 5.89
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 5.86
Differential gene expression of human melanoma cells [RNA-seq] 5.86
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 5.86
Changes in human endometrial gland transcriptome over the window of implantation 5.82
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 5.81
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 5.74
Gene expression of thyroid cancer cell lines 5.7
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 5.68
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 5.61
Redifferentiation of expanded human islet β cells by inhibition of ARX 5.56
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs 5.5
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines 5.46
Capturing the Interactome of Newly Transcribed RNA 5.46
Capturing the Interactome of Newly Transcribed RNA (RICK) 5.46
RNA-sequencing of milk cells extracted from pre-partum secretions and longitudinally from mature human milk across the first year of lactation 5.44
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 5.43
Reprogrammed myeloid cell transcriptomes in NSCLC 5.33
RNA seq analysis of human Fetal and adult derived Enterospheres 5.13
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 5.07
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 5.02
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 4.97
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 4.94
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 4.91
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 4.75
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 4.75
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 4.73
Ro60-knockout cells 4.49
An siRNA screen identifies CHD4 as a target for epigenetic therapy 4.31
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 4.31
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 4.26
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 4.22
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 4.19
The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactions 4.13
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 4.12
RNA sequencing of human pancreatic cancer cell lines 4.08
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 4.01
Genome-wide mapping of TEL-AML1 targets in acute leukemia 3.98
Total RNA-Seq data from leukemic patients with complex structural variants 3.98
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 3.95
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 3.91
Next generation sequencing of small RNAs isolated from exosomes in human semen 3.91
Effect of SF3B1 suppression in cancer cells with different SF3B1 copy-number levels 3.89
Genome-wide discovery of human splicing branchpoints [RNAse] 3.86
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 3.85
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 3.85
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 3.83
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 3.81
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 3.71
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 3.68
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 3.66
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 3.64
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 3.64
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 3.5
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 3.45
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines 3.43
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines [RNA-seq] 3.43
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 3.42
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 3.4
ML29755 RNA-seq data 3.33
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 3.31
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 3.3
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 3.3
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 3.26
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors 3.25
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq] 3.21
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels 3.21
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 3.2
CSL RNA-Seq on HKC and SCC cell lines 3.19
CSL 3.19
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 3.13
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells 3.05
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 2.96
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 2.96
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 2.9
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 2.86
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 2.86
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 2.84
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 2.79
Rate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications 2.73
Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells 2.65
6mer seed toxicity in tumour suppressive microRNAs 2.62
iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension 2.48
RNA-seq of MDA-MB-231 cells with TET1 knockout 2.47
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 2.46
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 2.38
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 2.37
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 2.34
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 2.33
Assessing placental maturity through histological and transcriptomic analyses in idiopathic spontaneous preterm birth 2.28
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 2.25
RNA-seq analysis of the human fetal kidney. 2.0
Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines. 1.9
Genome-wide expression analysis of young, senescent and p38MAPK-inhibitited senescent human fibroblasts. 1.83
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 1.78
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 1.77
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 1.75
STX4 Over-Expression in Human islets 1.64
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 1.56
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 1.53
RNA-seq of exosomes identifies lncRNA profiles that distinguish early-stage esophageal squamous cell carcinoma (ESCC) from non-malignant esophagitis 1.49
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 1.47
Deep RNA sequencing of the human placental transcriptome 1.45
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 1.35
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 1.33
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 1.27
Next Generation Sequencing identifying the dosage compensation state in human endometrial carcinoma and adjacent tissues 1.24
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 1.24
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 1.24
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.08
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 1.05
Gene expression and genome-wide location analysis of breast cancer cell-lines 1.02
Gene expression analysis of breast cancer cell-lines 1.02
RNAseq of Breast cancer PDX samples 0.98
Zika virus infection reprograms global transcription of host cells to allow sustained infection 0.96
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 0.94
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.88
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.88
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 0.88
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 0.85
Patient-derived xenograft platform for metastatic melanoma: a model for studying resistance to targeted therapy. 0.82
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 0.64
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.61
HEXIM1 is induced by DHODH inhibition to suppress melanoma 0.59
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 0.59
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes: Singapore Cohort RNA-seq 0.59
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes 0.59
Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia 0.51
Multi-omic measurements of heterogeneity in HeLa cells across laboratories 0.42
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.4
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.4
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 0.25
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.23
Transcriptomic analysis of human macrophages in 3D 0.22
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 0.2
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 0.2
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 0.19
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas 0.19
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 0.19
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 0.18
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 0.16
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) in proliferation, quiescence, senescence and transformed states. 0.16
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 0.11
Gene expression regulated by CSA and CSB in neuroblastoma cell line 0.11
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.1
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 0.09
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 0.06


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