Gene Query: FLNC

Dataset Description Geneva Score
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 201.6
Codon usage optimization in pluripotent embryonic stem cells [tRNA sequencing] 191.4
Transcriptome-wide analysis of adipose circular RNAs reveals their dynamic regulation in obesity and functional role in adipogenesis 140.03
DIGIT regulates endoderm differentiation of human embryonic stem cells 136.52
Gene Expression Profiling of SPOP Knocked Down Cell 120.47
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 105.08
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 105.08
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 103.87
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 100.58
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 100.58
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 100.18
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 91.49
SUV420H2 knockdown in PANC-1 90.43
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 90.29
Targeting EZH2 in MYCN-amplified Neuroblastoma 90.29
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 88.61
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 85.97
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 85.97
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 81.52
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 78.29
Nutritional control of protein translation 77.45
Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [RNA-Seq] 75.71
ETV7 and interferon response 75.42
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 75.42
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 74.76
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 73.7
METTL3 promotes translation in human cancer cells 71.08
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 69.93
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 69.93
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 69.09
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 68.8
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 67.98
RNA-Seq analysis of breast cancer cells after shikonin treatment 67.09
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 62.59
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 62.56
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 62.36
tRNA modification landscape selectively controls mitochondrial translation efficiency in MERRF 61.99
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 61.74
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 61.42
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 61.35
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 60.6
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia 60.19
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq] 60.19
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 59.05
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 58.92
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 58.57
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 57.9
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 57.15
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 56.69
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 56.45
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 56.34
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 54.68
Primary human trophoblast from term placenta 54.37
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 54.23
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 53.58
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 53.52
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 53.12
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 52.16
SRSF2 mutations impair hematopoiesis and alter exon recognition 52.09
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 51.9
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 51.7
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 51.02
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 50.98
RNA-seq of human iPS derived macrophages with or without KLF1- transcription factor Activation 50.85
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 50.71
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 50.71
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 50.04
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 49.95
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 49.95
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 49.67
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 49.06
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 49.06
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 48.49
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 48.49
Characterization of parental and rociletinib-resistant derived H1975 cell lines 48.04
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 47.76
RNA-seq analyisis of PUM2 knockout cells 47.57
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 47.39
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 47.39
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 47.36
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 46.89
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 46.89
Identification of long noncoding RNAs regulated by p53 46.58
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 45.66
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 45.5
DJ-1 is dispensable for human stem cell homeostasis 44.99
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 44.89
Spliceosomal disruption of the non-canonical BAF complex in cancer 44.36
BAF controls genome accessibility 44.14
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 44.06
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 43.97
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 43.97
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 43.17
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 42.97
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 42.97
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 42.71
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 42.35
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 42.04
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 41.5
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 41.14
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 40.95
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 40.86
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 40.83
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 40.75
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 40.61
Chromatin-informed inference of transcriptional programs in gynecologic cancers 40.61
RNA-seq in HepG2 and IMR90 cells 40.53
Evolution of a transcriptional regulator from a transmembrane nucleoporin 40.53
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 40.31
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 40.31
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 39.91
Fbxo32 mediated gene expression program underlies EMT and metastasis 39.88
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 39.77
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 39.49
Transcriptomic of MKD (MUC1 kidney disease) patient compares to normal derived kidney epithelial cells 39.37
Wide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling 38.55
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 38.13
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma [RNA-Seq; normal samples] 37.29
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 37.12
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 37.12
High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues 37.07
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 37.0
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 37.0
RNA-seq of overgrown interscapular adipose tissue with biallelic MFN2 mutations 36.95
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 36.91
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 36.87
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 36.79
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 36.65
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 36.5
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 36.43
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 36.14
MYCi975 regulates MYC target genes 36.01
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 35.77
Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells 35.76
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 35.62
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 35.51
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 35.43
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 35.23
MEIS1 regulates hematopoiesis in hPSCs 35.05
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 35.03
RNA splicing alteration on glioblastoma and normal neural stem cells 34.91
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 33.98
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 33.76
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 33.52
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 33.14
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 32.91
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 32.89
Mechanistic Model-Guided Study of Embryonic Morphogenesis 32.88
RNA-seq of MCF10A cells and CAF 32.59
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 32.48
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 32.17
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 32.1
The pause-initiation limit restricts transcription activation in human cells 32.09
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 31.71
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 31.67
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 31.63
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 31.46
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 31.32
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 30.92
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 30.87
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 30.78
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 30.78
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 30.54
Epigenomic landscape during organ formation in human early embryos 30.47
Histone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq] 30.32
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes 30.32
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 30.19
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 29.84
Effect of disulfiram treatment on pediatric high grade glioma 29.49
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 29.38
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 29.19
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 29.19
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 29.11
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 29.05
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 29.05
RNA-seq analysis of RALD iPSCs after in vitro differentiation 28.89
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 28.87
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 28.53
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 28.26
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 27.84
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 27.61
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 27.61
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 27.58
TCF7L1 knockdown in pancreatic cancer 27.4
Next Generation Sequencing of human SMA and healthy control Motor Neurons 27.01
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 26.95
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 26.93
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 26.93
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 26.9
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 26.8
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 26.72
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 26.71
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 26.71
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 26.49
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 26.24
Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids 26.15
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 26.06
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 25.83
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 25.62
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 25.6
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 25.51
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 25.51
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 24.87
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 24.81
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 24.75
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 24.74
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons 24.64
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 24.61
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 24.61
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 24.47
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 24.47
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 24.46
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 24.46
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 24.21
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 24.21
RNA Sequencing of three pairs of gastric cancer 24.16
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 24.09
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 24.09
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 24.02
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 23.67
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 23.59
Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle 23.3
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 23.18
RNA-seq analysis of AML cells in response to ASLAN003 22.71
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 22.69
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 22.58
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress [human] 22.53
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress 22.53
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 22.48
Global analyses of the effect of different cellular contexts on microRNA targeting 22.48
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 22.31
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 22.24
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 22.22
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 22.22
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 22.05
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 21.93
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 21.85
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 21.72
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 21.62
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 21.62
Lineage specific differentiation is influenced by state of human pluripotency 21.61
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 21.61
Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney 21.61
OBESITY IS ASSOCIATED WITH IMPAIRED EXPRESSION OF THE GLYCOSYLTRANSFERASE EOGT IN DECIDUALIZING ENDOMETRIUM 21.55
RNA sequencing with KSHV infection and enrichment for circular RNAs 20.99
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 20.99
RNA-seq of stable and unstable section of human atherosclerotic plaques 20.95
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 20.43
Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels 20.41
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 20.4
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 20.38
Transcriptome profiling of 5 human adenocarcinoma cell lines 20.3
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 20.29
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 20.2
Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues 20.05
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 20.0
Transcriptome analysis of H9 hESC derived cerebral organoids 19.99
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 19.85
Depicting early human development and germ cell origin with porcine embryos 19.8
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 19.7
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 19.64
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 19.63
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 19.62
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 19.61
Methylome, hydroxymethylome, and integrative transcriptome profiling in human CRC tissue and paired normal tissues 19.53
Tracking of dCas9-methyltransferase footprints 19.48
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 19.45
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 19.36
PNET animal model: new insights (II) 19.32
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 19.32
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 19.27
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 19.25
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 19.25
Widespread regulated alternative splicing of single codons accelerates proteome evolution 19.21
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 19.08
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 19.06
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 18.72
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells 18.68
MicroRNA Marker Based Prognostication of Oral Squamous Cell Carcinoma 18.68
Expression profiles of the four human major ectodermal lineages 18.65
Integrated Profiling of mRNAs and microRNAs to Identify Potential Biomarkers for Oral Malignant Transformation 18.65
Integrated Profiling of mRNAs and microRNAs to Identify Potential Biomarkers for Oral Malignant Transformation [mRNA-Seq] 18.65
Postnatal lipids drive hepatocyte maturation 18.45
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 18.4
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 18.36
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 18.21
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 17.92
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 17.92
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 17.9
Genome-wide Analysis of Chromatin Interactions in Human Cells 17.83
NHLRC1 re-expression in cancer cells 17.73
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 17.71
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 17.66
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 17.66
Lysine benzoylation is a novel histone mark [RNA-seq] 17.64
Lysine benzoylation is a novel histone mark 17.64
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 17.5
Genome-wide identification of cancer-specific alternative splicing in circRNA 17.45
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 17.4
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 17.22
Finding missing proteins from epigenetically manipulated human cells 17.15
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 17.07
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 17.07
Obstructed defecation – an enteric neuropathy? An exploratory study of patient samples 17.04
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 17.03
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 16.91
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 16.88
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 16.88
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 16.86
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 16.75
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 16.75
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 16.55
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 16.55
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 16.48
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 16.32
Induced DNA demethylation, genome instability and transcription 16.32
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 16.2
Rate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications 16.13
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 16.11
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 16.06
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 15.93
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 15.92
Profiling gene expression changes in primary ovarian tumors compared to matched normal fallopian tubes 15.73
Gene expression profile in breast cancer cell lines using RNA sequencing 15.69
Solid phase chemistry to covalently and reversibly capture thiolated RNA 15.66
Large-scale profiling of intracellular signalling pathway activation reveals major distinctions between airway smooth muscle cells of asthmatics and non-asthmatics. 15.63
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 15.53
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 15.44
The gene expression profiles of gallbladder cancer 15.41
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 15.31
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 15.31
Gene expression changes in human melanoma cell lines compared to primary melanocytes 15.29
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 15.25
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 15.25
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 15.25
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 15.25
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 15.2
The landscape of alternative splicing in aggressive prostate cancers 15.07
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 14.93
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 14.92
RNA-Seq analysis of neurons derived from induced pluripotent stem cells reprogrammed from dental pulp 14.71
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 14.58
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 14.38
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 14.34
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 14.32
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 14.28
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 14.17
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 14.13
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 13.99
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 13.98
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 13.86
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 13.7
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 13.69
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 13.31
The Genomic Landscape of Atypical Fibroxanthoma 13.27
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 13.26
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 13.26
RNA sequencing of prostate cancers reveal insights on the prognostic significance of visibility on multi-parametric MRI 13.21
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 13.14
Gene expression patterns define the hepatocyte-like cells derived by different strategies [RNA-seq] 13.04
Gene expression patterns define the hepatocyte-like cells derived by different strategies 13.04
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 12.9
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 12.9
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 12.77
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 12.58
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 12.58
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 12.37
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 12.04
The effect of insulin on mRNA transcription of human pluripotent stem cells 11.96
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 11.8
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 11.8
RNA expression profiles comparing primary and omental ovarian carcinoma samples 11.68
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 11.65
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 11.62
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 11.6
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 11.58
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 11.26
hESC neural differentiation 11.2
RNA-seq analysis of gene expression patterns during hESC neural differentiation 11.2
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 11.15
The transcriptome of Kawasaki Disease arteritis 10.91
The mRNA expression analysis of psoriasis skin lesion mesenchymal stem cell 10.9
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells with PolyIC treatment 10.77
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 10.6
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 10.6
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 10.43
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 10.15
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 10.07
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 10.07
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 10.04
RNA-sequencing of human tendon after injury 10.03
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 9.93
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 9.9
RNA Sequencing Analysis of villus tissues from unexplained recurrent spontaneous abortion patients and controls with induced abortions 9.79
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 9.78
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 9.77
Mutations in EBF3 disturb transcriptional profiles and cause intellectual disability, ataxia and facial dysmorphism 9.72
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 9.65
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 9.63
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 9.58
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 9.39
Gene Expression Signature in Adipose Tissue of Acromegaly Patients 9.36
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 9.24
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 9.15
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 9.07
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 9.07
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 8.98
Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines. 8.94
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 8.91
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 8.9
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 8.8
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 8.8
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 8.65
Transcriptome analysis reveals differential splicing events in IPF lung tissue 8.64
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 8.62
Identification of a core p53 transcriptional program with highly fractionated tumor suppressive activity 8.57
GRO-seq from HCT116, MCF7 and SJSA cell lines treated with DMSO and Nutlin 8.57
Genome-wide discovery of human splicing branchpoints [RNAse] 8.51
Genome-wide discovery of human splicing branchpoints 8.48
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 8.37
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 8.11
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 8.03
Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells 7.96
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 7.91
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 7.9
Next Generation Sequencing identifying the dosage compensation state in human endometrial carcinoma and adjacent tissues 7.83
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 7.39
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 7.18
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 7.17
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 7.12
Functional astrocytes differentiated from hiPSCs 6.98
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 6.92
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 6.85
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 6.8
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 6.63
Zika virus infection reprograms global transcription of host cells to allow sustained infection 6.58
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 6.29
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 6.27
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 6.21
Gene profiling of human adult and pediatric liver cancer cells 6.08
Pluripotent stem cell models of Blau syndrome reveal an IFN-<gamma>-dependent inflammatory response in macrophages 5.96
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 5.95
Transcriptional analysis of ZIKV-infected Ifnar-/- and Ifnar+/- placentas and IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 5.67
Analysis of transcriptional differences after IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 5.67
An acquired vulnerability of drug resistant melanoma with therapeutic potential 5.37
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 5.37
The Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth 5.19
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 5.1
Identification of expressed and conserved human non-coding RNAs 4.88
Landscapes of gene translation in hepatocellular carcinoma tumors revealed by ribosome profiling 4.85
Gene expression regulated by CSA and CSB in neuroblastoma cell line 4.65
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 4.62
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 4.35
RNA seq_PDX2_SHP099 4.33
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 4.24
FGF2 regulation of gene expression in stable inducible Neurons 4.2
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 4.09
Gene expression analysis in response to hypoxic pathway inhibition 4.01
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 3.9
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 3.83
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 3.7
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 3.62
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 3.55
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 3.55
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 3.23
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 3.21
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 3.13
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 3.12
Enhancement of Arterial Specification in Human Pluripotent Stem Cell Cultures Promotes Definitive Hematoendothelial Program with Broad Myelolymphoid Potential 2.94
Effect of SF3B1 suppression in cancer cells with different SF3B1 copy-number levels 2.88
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 2.79
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 2.79
Next Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs 2.77
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 2.73
Transcriptomic analysis of frontal fibrosing alopecia 2.72
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 2.68
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 2.35
Polycomb complexes associate with enhancers to promote oncogenic transcriptional programs in cancer 2.25
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 2.21
Differential responses of human fetal brain neural stem cells to Zika virus infection 2.18
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 1.95
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 1.88
RNA-seq of cancer cell lines treated with T-025 1.78
DAOY-Notch1/Notch2 knockout: transcriptome comparison 1.76
The Wnt/β-catenin and RAS-ERK Pathways were Activated in Tissues of Chemotherapy-Resistant Gastric Cancer PDX Tumor 1.45
Common inflammatory pathways between NEC and Crohn's disease 1.03
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 1.0
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 0.92
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 0.82
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 0.72
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 0.72
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 0.71
RNA-Seq of Breast and Ovarian Cancer Cell Lines 0.6
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 0.55
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.49
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2) 0.27
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells 0.27
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 0.21
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 0.09
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.01


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