Gene Query: GAD1

Dataset Description Geneva Score
RNA sequencing analysis of human embryonic stem cells and axial progenitors 93.01
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 87.31
RNA sequencing of BT142 and TS603 cell lines 87.31
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 74.8
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 74.8
CHCHD10 gene KO effect in iPSC drived motor neurons 67.14
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 64.39
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 64.21
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 50.8
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 50.8
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 47.39
RNA-Seq from early time points in the kidney differentiation protocol 46.1
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 39.86
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 34.66
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 34.66
SRSF2 mutations impair hematopoiesis and alter exon recognition 33.68
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 32.48
Differential gene expression profiles in imatinib-resistant cell lines 32.4
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 31.64
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 30.57
RNA sequencing of hPSC-derived cardiac progenitors and endocardium 30.26
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 30.03
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 29.84
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 29.78
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 28.98
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 28.98
CHCHD2 gene KO effect in iPSC drived motor neurons 28.6
Regionally specified human pluripotent stem cell-derived astrocytes 28.54
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 28.21
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 27.6
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 27.59
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 25.74
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 25.74
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 24.04
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 22.92
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 22.29
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 22.26
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 21.25
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 19.57
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 19.29
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 18.75
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 17.89
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 17.23
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 17.09
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 16.41
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 16.41
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 16.39
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 16.08
RNA-Seq of the corpus callosum from 12 individuals 15.81
The pause-initiation limit restricts transcription activation in human cells 15.8
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 15.7
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 15.52
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 15.48
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 15.08
The Glioma-Infiltrating T Cell Receptor Repertoire 14.81
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 14.64
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 14.64
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 14.58
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 14.29
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 14.19
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 13.72
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 12.87
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 12.56
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 12.09
Disruption of GRIN2B impairs differentiation in human neurons 11.63
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 10.93
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 10.92
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 10.66
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 10.66
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 10.66
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 10.62
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 10.48
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 10.31
FOXP1 orchestration of ASD-relevant signaling pathways. 10.11
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 10.07
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 10.07
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 9.94
Depicting early human development and germ cell origin with porcine embryos 9.83
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells via Transcription Factor Conversion of Hemogenic Endothelium 9.45
WRN knockout effects upon gene expression in SW48 and OVK18 9.39
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 9.33
9.05
Glioma Stem Cell Specific Super Enhancer Drives Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling 8.97
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 8.83
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 8.81
AR-independent prostate cancer is sustained through FGF signaling 8.59
Repurposing of promoters and enhancers during mammalian evolution 8.22
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain 8.13
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 8.03
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 7.98
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 7.93
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 7.93
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 7.85
Enhancement of Arterial Specification in Human Pluripotent Stem Cell Cultures Promotes Definitive Hematoendothelial Program with Broad Myelolymphoid Potential 7.7
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 7.7
RNA-seq of naive and primed ES cells (NHSM) 7.26
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 7.02
Alteration of the microRNA network during the progression of Alzheimer’s disease 7.02
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 7.02
RNA expression analysis upon JMJD1C depletion 7.0
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 7.0
Molecular Biomarkers Screened by Next-generation RNA Sequencing for non-sentinel lymph node status predicting in breast cancer patients with metastatic sentinel lymph node 6.81
GATA2 promotes hematopoietic development and represses cardiac differentiation of human mesoderm 6.77
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 6.76
Dynamic reorganization of nuclear architecture during human cardiogenesis [RNA-seq] 6.54
Dynamic reorganization of nuclear architecture during human cardiogenesis 6.54
Transcriptome of EBV-infected gastric cancer cell lines 6.52
The age and genomic integrity of neurons after cortical stroke in humans 6.51
Activity-dependent transcriptional changes in human neurons 6.41
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 6.38
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 6.38
RNAseq in Alzheimer's Disease patients 6.22
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 6.21
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 6.15
Lineage specific differentiation is influenced by state of human pluripotency 5.83
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 5.83
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 5.66
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 5.6
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 5.56
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 5.51
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 5.44
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 5.43
circRNA-sequencing 5.38
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 5.38
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 5.31
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 5.23
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 5.21
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 5.18
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 5.17
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 5.12
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 5.08
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 5.0
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 4.91
TAF1 is critical for AE driven leukemogenesis 4.91
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 4.88
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 4.83
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 4.83
Ectoderm specification of H1 human embryonic stem cells 4.83
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 4.81
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 4.81
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability 4.81
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [RNA-Seq] 4.81
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 4.81
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 4.77
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 4.77
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 4.76
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 4.66
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 4.62
Gene expression changes upon drug withdrawal (Mel888 cell line) 4.57
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 4.54
RNA-seq in endometrial stromal tumors 4.38
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 4.36
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 4.31
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 4.3
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 4.3
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 4.25
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 4.19
U2AF1 mutations alter splice site recognition in hematological malignancies 4.15
Transcriptomic responses to Ivacaftor and prediction of Ivacaftor clinical responsiveness 4.08
LIN28A Over-expression RNAseq 4.04
Genome-wide maps of H3K36me3 in ccRCC and RNA-seq of matched nephrectomy samples 4.04
RNA sequencing of matched nephrectomy samples [RNA-seq] 4.04
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 3.96
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 3.96
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 3.96
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 3.96
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 3.86
RNA-seq analysis of RALD iPSCs after in vitro differentiation 3.77
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 3.69
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 3.66
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 3.6
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 3.6
BI Human Reference Epigenome Mapping Project 3.48
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 3.43
Gene expression profile of human iPSC-derived nephron progenitor cells 3.31
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 3.28
Universal alternative splicing of noncoding exons 3.28
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 3.22
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 3.21
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 3.19
Molecular Criteria for Defining the Naive Human Pluripotent State 3.13
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 3.13
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 3.12
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 3.12
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 3.1
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 3.1
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 3.05
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 3.02
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 2.99
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 2.99
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 2.98
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 2.97
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 2.97
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 2.94
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 2.9
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 2.86
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 2.86
Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient 2.86
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 2.85
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 2.85
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 2.85
DIGIT regulates endoderm differentiation of human embryonic stem cells 2.84
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 2.84
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 2.84
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 2.78
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 2.76
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 2.75
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 2.75
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 2.65
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 2.65
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 2.61
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 2.61
Analysis of human, chimpanzee, macaque and mouse tissue transcriptomes using Next Generation Sequencing 2.6
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 2.6
Gene expression changes in human melanoma cell lines compared to primary melanocytes 2.6
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 2.6
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 2.58
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 2.58
JAK dependent survival of ALK- ALCL 2.57
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 2.57
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 2.52
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 2.51
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 2.46
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 2.45
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 2.43
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 2.43
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 2.37
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 2.37
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 2.37
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 2.37
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 2.37
Global analysis of enhancer targets: Mosaic-seq 2.35
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines 2.28
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [human] 2.27
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug 2.27
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 2.25
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 2.24
METTL3 promotes translation in human cancer cells 2.24
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 2.24
Human optic chiasm from healthy controls and multiple sclerosis patients 2.23
Multiple sclerosis and EAE 2.23
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 2.22
Total RNA sequencing of WT intestinal orgaonids. 2.21
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 2.2
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 2.18
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 2.18
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 2.17
Gene expression analysis upon mtDNA depletion [RNA-seq] 2.17
Gene expression analysis upon mtDNA depletion 2.17
Functional astrocytes differentiated from hiPSCs 2.12
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 2.11
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 2.11
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 2.1
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 2.09
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 2.02
Global transcriptome analysis of WT versus HEB-/- hESCs 2.01
RNA seq with AML (NB4) cells upon FTO inhibition 1.99
Integrated epigenomic and transcriptomic profiling of terminal human erythropoiesis [TMCC2] 1.96
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 1.94
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 1.94
Cajal bodies are linked to genome conformation 1.91
Cajal bodies are linked to genome conformation [RNA-Seq] 1.91
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 1.89
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 1.88
RNA-Seq analysis of breast cancer cells after shikonin treatment 1.87
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 1.85
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 1.84
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 1.83
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 1.83
Transcriptome analysis of human reninomas as an approach to understanding juxtaglomerular cell biology 1.82
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 1.82
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 1.81
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 1.81
Maturation of human iNSCs 1.79
Dissecting neural differentiation regulatory networks through epigenetic footprinting 1.78
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 1.78
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 1.76
High-resolution comparative analysis of great ape genomes 1.75
Hypoxic transcriptome of SQ20B human head and neck cancer cells 1.75
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 1.74
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 1.74
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 1.72
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 1.72
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 1.7
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 1.69
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 1.68
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 1.68
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 1.68
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 1.64
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 1.63
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 1.63
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 1.62
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 1.62
Examining serotonergic neuron differentiation from human iPSCs 1.6
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 1.6
RNA-seq transcriptonal profiling in human K562 cells with or without dCas9 and sgRNAs 1.59
In situ CAPTURE of chromatin interactions by biotinylated dCas9 1.59
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 1.59
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 1.58
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 1.55
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 1.55
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 1.55
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 1.52
TT-Seq captures the human transient transcriptome 1.5
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 1.5
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 1.47
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 1.46
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 1.46
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 1.44
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 1.42
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 1.4
MEIS1 regulates hematopoiesis in hPSCs 1.39
LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression 1.38
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 1.38
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 1.37
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 1.35
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 1.35
Crizotinib v. DMSO in SW480 cells 1.34
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 1.33
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 1.33
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 1.33
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 1.28
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 1.28
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 1.28
Identification of expressed and conserved human non-coding RNAs 1.26
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 1.26
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 1.25
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 1.24
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 1.24
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 1.24
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 1.23
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 1.23
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 1.23
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 1.22
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 1.22
Noncoding regions are the main source of targetable tumor-specific antigens 1.21
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 1.19
Single-cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos 1.18
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 1.18
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 1.17
TOP2B disturbed the quality of human oocytes with advanced maternal age 1.17
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 1.16
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 1.16
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 1.16
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 1.16
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 1.14
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 1.11
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 1.1
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 1.09
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 1.09
Global analysis of alternative splicing regulated by RBM10 1.09
Integrin signaling regulates YAP/TAZ to control skin homeostasis 1.09
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 1.08
Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis 1.08
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.06
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 1.05
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 1.05
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 1.01
Generating Patterned Kidney Organoids for Studying Development and Diseases 1.0
High-throughput sequencing of pluripotent cells 1.0
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 0.99
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 0.99
Analysis of the Clustered Protocadherin (cPcdh) Locus in Human Pluripotent Stem and Derived Cells [RNA-seq II our of II] 0.98
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 0.98
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 0.97
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 0.96
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 0.96
Global reduction in H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 0.95
SETBP1-WT and SETBP1-G870S epigenetic landscapes 0.94
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 0.94
LINE-2 transposable elements are a source of functional human microRNAs and target sites 0.94
Differential responses of human fetal brain neural stem cells to Zika virus infection 0.91
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.91
Total RNA sequencing of APC mutant and wt colonic organoids 0.91
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 0.9
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 0.9
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 0.9
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 0.9
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 0.87
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 0.85
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 0.85
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 0.84
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 0.83
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 0.83
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.83
Modulation of ESRP2 and MBNL2 in normal kidney and clear cell renal cell carcinoma cell lines for analysis of stability programs 0.81
iPSC derived motor neuron cultures from C9ORF72 carriers 0.81
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 0.79
Transcriptional responses of melanoma cells to BRAF inhibition 0.79
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 0.79
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 0.76
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 0.76
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.75
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 0.74
RNA-Seq in PWS iPSC-derived neurons 0.72
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 0.71
Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury 0.65
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 0.61
Profiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis 0.61
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 0.6
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 0.59
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 0.59
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 0.58
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 0.58
Dynamic 3D chromosomal landscapes in acute leukemia 0.58
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 0.57
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 0.57
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 0.57
Gene profiling of human adult and pediatric liver cancer cells 0.56
Transcriptomic analysis of human iPS cells derived from fragile X syndrome patients during neural differentiation 0.56
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 0.55
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 0.55
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 0.54
Derivation and differentiation of haploid human embryonic stem cells 0.53
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 0.53
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 0.53
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.52
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 0.51
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.51
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 0.51
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 0.5
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 0.5
Engineering Patient-Specific Tissue Implants 0.49
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.49
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 0.47
Radiation enhances melanoma response to immunotherapeutic and synergizes with benzodiazepines to promote improved anti-tumor activity 0.46
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 0.46
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 0.45
Gene Expression Profiling of WT and KDM3A Knocked out Cell 0.45
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.45
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 0.45
Expression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions. 0.45
Gene expression for surgically treated pancreatic cancer after one neoadjuvant vaccine dose 0.44
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 0.44
Identification of long noncoding RNAs regulated by p53 0.42
Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny 0.42
RNA-seq of exosomes identifies lncRNA profiles that distinguish early-stage esophageal squamous cell carcinoma (ESCC) from non-malignant esophagitis 0.42
Proteomics identifies a marker signature of MAPKi resistance in melanoma 0.41
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 0.41
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 0.39
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 0.38
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 0.37
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.37
Impact on erythroid progenitor type on erythroid differntiation 0.36
BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage (Gene expression profiling in several tetrapod species, bulk tissue RNA-seq) 0.35
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 0.35
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells 0.35
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 0.34
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.34
hESC neural differentiation 0.34
RNA-seq analysis of gene expression patterns during hESC neural differentiation 0.34
Transcriptional profiling of healthy, eutopic and ectopic endometrial organoids 0.34
nELAVL HITS-CLIP in Alzheimer's Disease patients 0.34
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.33
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.33
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 0.31
6mer seed toxicity in tumour suppressive microRNAs 0.29
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.29
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 0.29
Compare of gene expression between p16INK4A positive and negative regions of colon cancer from five patients 0.27
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 0.26
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 0.26
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 0.25
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 0.25
Transcriptional dependencies in diffuse intrinsic pontine glioma 0.24
Intrinsic histone acetyltransferase activity of BRD4 is responsible for nucleosome eviction and transcriptional activation 0.24
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 0.22
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 0.22
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 0.22
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 0.21
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 0.21
RNA deep sequencing analysis of glioma stem cells(GSCs) and non-GSCs 0.2
Derivation and differentiation of haploid human embryonic stem cells [RNA-Seq 1] 0.2
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 0.19
STX4 Over-Expression in Human islets 0.19
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 0.19
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 0.17
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 0.16
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 0.15
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 0.14
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 0.14
Discovering human diabetes-risk gene function with genetics and physiological assays 0.13
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.12
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 0.12
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 0.12
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 0.09
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 0.08
Induced DNA demethylation, genome instability and transcription 0.08
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.08
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 0.07
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 0.07
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 0.06
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 0.06
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 0.06
Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease 0.03
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.03
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 0.02
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 0.02
RNA-seq analysis of differentiating human erythroblasts 0.01
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 0.01


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