Gene Query: GSTCD

Dataset Description Geneva Score
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 33.87
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 14.56
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 11.25
KSDM1b Role in Ewing Sarcoma 10.02
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 8.91
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 7.27
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 7.17
Transcriptional landscape changes during human embryonic stem cell derivation 6.97
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 6.58
RNAseq analysis of ESRP regulated splicing events in prostate cancer 6.32
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 6.28
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 6.26
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 6.16
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 6.05
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 6.05
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 5.88
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 5.85
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 5.81
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 5.81
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 5.8
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 5.66
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 5.65
TGF-β regulation of miRNA expression in pancreatic cancer 5.57
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 5.56
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 5.34
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  5.3
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 5.21
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 5.0
ETV7 and interferon response 5.0
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 4.91
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 4.87
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 4.85
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 4.83
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 4.76
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 4.68
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 4.64
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 4.59
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 4.55
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 4.44
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 4.43
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 4.42
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 4.38
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 4.36
RNAseq Study in CC-671 Treated Cal-51 Cells 4.34
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 4.24
A Unique Epigenomic Landscape Defines Human Erythropoiesis 4.24
RNA-seq data from human lymphoma cell lines 4.2
ChIP-seq and RNA-seq from human lymphoma cell lines 4.2
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 4.19
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 4.17
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 4.17
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 4.16
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 4.15
Hijacking of stress response machinery by oncogenes in acute leukaemia 4.15
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 4.13
Tracing transcriptome profiles of human oocyte cultured by growth hormone or not in vitro by single cell RNA-seq 4.12
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 4.05
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 4.05
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 4.04
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 4.02
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 4.0
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 4.0
Downregulation of DDX5/DDX17 and REST 3.98
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 3.97
LNCaP treated with iBET 3.94
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 3.92
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 3.89
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 3.88
Regulation of protein translation during mitosis 3.86
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 3.85
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 3.83
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 3.83
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 3.79
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 3.78
ARS2 is a general suppressor of pervasive transcription [RNAseq] 3.78
The Human Testis Cell Atlas via Single-cell RNA-seq 3.75
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 3.74
Characterization of sperm lncRNA and its differently expression in the sperm of asthenozoospermic patients 3.69
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 3.65
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 3.63
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 3.63
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 3.63
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 3.6
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 3.6
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 3.6
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 3.57
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 3.55
Oncogenic MYC induces a dependency on the spliceosome in human cancer 3.53
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples 3.52
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 3.52
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 3.51
Developmental stage specific chromosome architecture in human erythroid cells 3.51
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 3.51
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 3.48
A sister of NANOG regulates genes expressed in pre-implantation human development 3.45
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 3.44
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 3.44
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 3.43
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 3.41
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 3.38
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 3.36
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 3.35
SLIGRL-induced gene expression changes in NHEK cells 3.32
RNAseq Analysis in glioblastoma cells treated with Mepazine 3.32
IDH3a KO RNA-seq 3.32
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 3.31
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 3.3
HBEC-shp53-PCHD7 3.29
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 3.29
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 3.21
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 3.17
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 3.16
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 3.09
Paxillin regulates genomic networks in prostate cancer [LNCaP] 3.08
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 3.08
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 3.06
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 3.05
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 3.04
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 3.03
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 3.03
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 3.0
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 2.99
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 2.99
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 2.96
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 2.96
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 2.92
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 2.91
LncRNA-GAS5 negative regulation of YAP-target genes expression 2.89
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 2.88
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 2.87
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 2.87
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 2.87
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 2.86
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 2.86
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 2.86
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 2.81
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 2.8
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 2.8
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 2.76
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 2.75
The Human Testis Cell Atlas via Single-cell RNA-seq (Healthy men scRNA-seq data set) 2.73
Differential expression of genes in AD169-infected MRC5. 2.73
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 2.69
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 2.69
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 2.66
Impact of dieldrin on transcription in Jurkat T cells 2.65
RNA sequencing of matched nephrectomy samples [RNA-seq] 2.64
Genome-wide maps of H3K36me3 in ccRCC and RNA-seq of matched nephrectomy samples 2.64
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 2.63
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 2.61
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 2.61
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 2.6
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 2.6
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 2.6
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 2.59
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 2.58
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 2.55
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 2.52
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 2.51
Knockdown of ADNP in HCT116 colon cancer cells 2.49
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 2.49
FBXW7 modulates stress response by post-translational modification of HSF1 2.46
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 2.46
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 2.44
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 2.44
RNA-seq of naive and primed ES cells (NHSM) 2.42
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 2.42
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 2.41
SNHG5 siRNA knock down in HCT116 cells 2.4
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 2.4
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 2.4
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 2.39
Identification of global regulators of T-helper cell lineage specification 2.39
MYCL and EP400 are required for Max and MCPyV mediated gene activation 2.39
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 2.38
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 2.37
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 2.37
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 2.37
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 2.37
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 2.36
The landscape of alternative splicing in aggressive prostate cancers 2.36
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 2.35
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 2.35
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 2.35
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 2.32
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 2.31
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 2.31
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 2.31
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 2.3
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 2.28
Low-Cell-Number, Single-Tube Amplification (STA) of RNAs Revealed miRNA Changes from Pluripotency to Endothelium 2.27
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 2.26
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 2.25
Allelic expression mapping across cell lineages reveal repressor disruption among disease SNPs 2.25
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 2.24
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 2.24
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 2.24
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 2.24
Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney 2.23
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 2.22
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 2.22
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 2.22
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 2.21
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 2.21
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 2.21
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 2.19
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 2.19
2.16
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 2.16
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 2.15
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 2.15
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 2.14
Inhibition of TNBC metastasis by Gpx1 2.14
LIN28A Over-expression RNAseq 2.13
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 2.12
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 2.12
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 2.11
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 2.11
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 2.11
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 2.09
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 2.09
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 2.08
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 2.08
High-efficiency RNA-based reprogramming of human primary fibroblasts 2.02
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 2.01
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 2.0
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 1.99
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 1.96
Systematic discovery of endogenous human ribonucleoprotein complexes 1.96
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 1.96
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 1.95
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 1.94
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 1.93
HEXIM1 is induced by DHODH inhibition to suppress melanoma 1.93
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 1.93
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 1.93
ARID1A and ARID1B loss in HCT116 and TOV21G cells 1.92
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 1.91
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 1.9
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 1.89
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 1.89
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 1.89
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 1.89
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 1.88
The cohesin complex prevents Myc-induced replication stress 1.88
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 1.87
RNA sequencing of mechanically strained NHEKs and control NHEKs 1.87
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 1.87
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 1.87
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 1.86
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 1.86
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 1.86
Biological effect of chronic mistranslation in mammalian cells 1.86
Differentially expressed genes post knock down of lincDUSP26 1.85
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 1.85
The cohesin release factor WAPL restricts chromatin loop extension. 1.85
RNA-seq of resting and activated CD4+ T cells +-JQ1 1.85
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 1.84
ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq) 1.84
U2AF1 mutations alter splice site recognition in hematological malignancies 1.83
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 1.82
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 1.82
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 1.81
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 1.81
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 1.8
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 1.79
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 1.79
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 1.76
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 1.71
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 1.7
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 1.7
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 1.69
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 1.69
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 1.68
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 1.68
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 1.67
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 1.67
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 1.67
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 1.64
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 1.64
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 1.64
The conserved transcriptional landscapes in human spermatogenesis 1.64
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 1.63
FOXP2's impact on the primate transcriptome 1.62
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 1.62
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 1.62
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 1.62
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 1.62
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 1.61
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 1.6
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 1.59
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 1.59
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 1.59
Selective expression of long non-coding RNAs in a breast cancer cell progression model 1.58
Splicing and epigenetic factors jointly regulate epidermal differentiation 1.57
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 1.57
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 1.56
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 1.55
Studying the selectivity of a small molecule Synucleozid on transcriptome 1.54
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 1.54
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 1.53
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 1.51
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 1.51
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 1.5
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 1.5
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.49
Dnmt3a and Dnmt3b associate with enhancers to regulate human epidermal stem cell homeostasis 1.49
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 1.49
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 1.49
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 1.48
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 1.47
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 1.46
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 1.46
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 1.46
Effect of from Human Umbilical Vein Endothelial Cells 1.45
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 1.45
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 1.43
Integrin signaling regulates YAP/TAZ to control skin homeostasis 1.43
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 1.41
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 1.41
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 1.4
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 1.4
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 1.39
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 1.39
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 1.38
AKAP8 inhibits tumor metastasis by antagonizing EMT-associated RNA alternative splicing 1.35
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 1.32
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 1.32
6mer seed toxicity in tumour suppressive microRNAs 1.31
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.3
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 1.3
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 1.3
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 1.28
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 1.28
Human cells contain natural double-stranded RNAs with potential regulatory capacity 1.27
Mutational landscape of splicing genes and functional consequences across 33 cancer types 1.27
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 1.27
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 1.27
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 1.25
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 1.22
Gene expression profiling study by RNA-seq in PDX model based diffuse type gastric cancers. 1.22
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 1.2
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 1.2
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 1.2
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.19
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.19
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 1.17
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 1.17
Hepatitis C virus functionally sequesters miR-122 1.17
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 1.17
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 1.15
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 1.14
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 1.14
A High-Throughput Screen Identifies DYRK inhibitor ID-8 that Stimulates Human Kidney Tubular Proliferation 1.14
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 1.14
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 1.14
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.12
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.12
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 1.11
Role of FGFR1 in neuronal devlopment 1.11
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 1.09
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.05
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 1.05
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 1.05
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 1.02
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 1.02
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.01
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 1.01
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.0
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.0
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 0.99
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 0.99
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 0.99
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 0.98
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.98
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 0.97
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 0.95
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 0.93
Controlling for gene expression changes in transcription factor protein networks. 0.93
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 0.93
Molecular Criteria for Defining the Naive Human Pluripotent State 0.89
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 0.88
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 0.88
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 0.88
Gene expression changes due to PARP knockdown in human cells 0.87
K562 polyA RNA-Seq 0.86
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 0.86
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 0.85
Identification of long noncoding RNAs in T-ALL cell lines 0.85
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 0.85
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 0.83
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 0.83
Epigenetic reprogramming of melanoma cells by vitamin C treatment 0.81
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 0.81
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 0.78
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 0.78
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.77
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 0.76
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 0.75
BASP1 modifies the Tamoxifen response 0.75
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 0.73
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 0.73
The transcriptome effect of overexpressing EZH2 in MCF7 0.73
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 0.72
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.71
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.71
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.65
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.65
Real-time observation of light-controlled transcription in living cells 0.62
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 0.62
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 0.6
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 0.59
Effect of PRDM11 depletion in U2932 cells 0.58
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 0.57
Xeno-free and Chemically Defined Human System for Culturing Human Epidermal Keratinocytes 0.57
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.57
Identification of global XBP1s target gene expression in human prostate cancer cells 0.55
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 0.55
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 0.55
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 0.55
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 0.55
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 0.54
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.54
Low H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 0.53
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 0.52
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 0.52
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 0.49
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 0.45
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 0.45
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 0.44
p53 activity results in DNA replication fork processivity 0.44
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 0.43
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 0.43
RNA-seq of cancer cell lines treated with T-025 0.41
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.4
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 0.4
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 0.4
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 0.39
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 0.38
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 0.35
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 0.35
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 0.35
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells [RNA-Seq] 0.35
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells 0.35
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 0.32
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 0.32
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 0.32
Persistence of stem cell metabolism in cancers as a failure of differentiation 0.31
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.31
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 0.29
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.28
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.28
RNA-seq of MDA-MB-231 cells with TET1 knockout 0.28
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 0.26
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.26
Functional significance of the HIV-1 Tat signature amino acid residues 0.25
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 0.24
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.24
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 0.23
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 0.23
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.23
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 0.23
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 0.22
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 0.22
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 0.22
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.21
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 0.21
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 0.2
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 0.2
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 0.19
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 0.18
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 0.18
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.18
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 0.18
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 0.16
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.15
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 0.14
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.12
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.11
Identification of a LIF-responsive replication-competent human β cell 0.11
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.1
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.09
Oncogenic roles of ARID5B in T-ALL 0.09
Modulation of nonsense-mediated decay by rapamycin 0.08
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.07
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.07
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 0.07
RNA-Sequencing of HepG2 cells treated with TGFBeta 0.05
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.05
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.05
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 0.04
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 0.04
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.04
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 0.04
Zika virus infection reprograms global transcription of host cells to allow sustained infection 0.03
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 0.03
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 0.02
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.02
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 0.01
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.0


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