Gene Query: H1FX

Dataset Description Geneva Score
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 89.6
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 89.6
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 86.45
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 83.24
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 62.14
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 58.84
Interleukin-1β induces mitochondrial DAMP production to activate STING-dependent innate immune programs 57.76
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 49.25
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 49.25
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 49.21
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 46.61
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 46.61
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 44.56
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 44.39
DART-seq: an antibody-free method for global m6A detection 42.33
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 39.72
Impact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST 39.38
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 38.91
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 38.59
RNA-seq analyisis of PUM2 knockout cells 38.42
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 37.18
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 36.88
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 36.88
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 36.63
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 36.21
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 35.59
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 35.16
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 33.94
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 33.94
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 33.43
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 33.43
LNCaP treated with iBET 33.36
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 33.29
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 32.03
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 31.22
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 30.2
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 29.51
Loss of the Chr16p11.2 candidate gene QPRT leads to aberrant neuronal differentiation 29.45
RNA-Seq from early time points in the kidney differentiation protocol 29.35
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 29.06
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 28.88
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 28.88
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 28.88
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 28.79
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 28.68
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 28.55
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 28.2
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 28.11
Co-regulation of splicing by Rbfox1 and hnRNP M 28.11
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  27.86
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 27.56
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq] 27.26
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma 27.26
Intrahepatic MAIT cell gene expression revealed by RNA-seq 27.25
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 26.58
N6-methyladenine DNA Modification in Glioblastoma 26.58
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 26.06
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 26.06
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 26.05
Expression and functions of long noncoding RNAs during human T helper cell differentiation 26.02
Identification of Sin3B regulated genes during quiescence 25.76
ROR-γ drives androgen-receptor expression and represents a therapeutic target in castration-resistant prostate cancer 25.71
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 25.33
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 24.96
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 24.9
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 24.87
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 24.85
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 24.67
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 24.37
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 24.37
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 24.1
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 24.04
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 24.04
Studying the selectivity of a small molecule Synucleozid on transcriptome 23.35
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 23.19
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 23.19
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 23.11
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 22.97
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 22.57
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 22.57
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 22.41
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 22.41
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 22.1
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 22.06
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 21.91
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 21.9
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 21.83
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 21.5
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 21.3
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 21.29
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 21.12
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 21.06
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 21.0
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 20.86
Differential gene expression of human melanoma cells [RNA-seq] 20.86
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 20.65
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 20.61
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 20.58
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 20.55
Expression profiling of MCF-7 cells with treatment of TCDD 20.55
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 20.53
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 20.53
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 20.48
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 20.41
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 20.39
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 20.33
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 20.29
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 20.2
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 19.91
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 19.77
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 19.54
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 19.48
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 19.36
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 19.27
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 19.25
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 19.25
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 19.05
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 18.97
Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21 (RNA-Seq) 18.97
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 18.94
Genome wide expression change by RNF168 knocking down in NEC cells 18.93
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 18.85
Transcriptome analysis of kidney organoids 18.84
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 18.74
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 18.74
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 18.74
DJ-1 is dispensable for human stem cell homeostasis 18.73
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 18.43
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 18.4
MAIT cell RNA sequencing 18.4
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 18.34
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 18.27
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 18.13
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 18.11
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 18.11
Genome wide expression change by RNF168 knocking down in MCF-7 cells 18.09
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 18.07
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 18.05
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 17.81
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 17.76
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 17.73
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 17.72
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 17.64
RNA-Seq of CD4+ T cells treated with AS1842856 or DMSO 17.63
Gene expression analysis of immortalized human liver progenitor-like cells in culture 17.4
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 17.29
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 17.24
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 17.01
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 17.0
Regulation of highly expressed hCINAP on translatome 16.96
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 16.92
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 16.87
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 16.56
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 16.53
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 16.4
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 16.36
Transcriptome of activated human and mouse MAIT cells 16.3
Total RNA-seq in ALL-SIL upon JQ1 inhibition 16.27
RNA-seq of cells with TET1 knockout 16.27
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 16.13
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 16.12
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 16.12
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 15.97
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 15.91
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 15.87
Illumina Total RNA-seq in HeLa 15.85
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2) 15.71
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 15.62
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 15.59
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 15.52
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 15.48
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 15.46
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 15.45
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 15.44
RNA-seq analyses of human prostate cancer cells 15.33
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 15.17
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 15.14
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 15.08
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 15.05
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 15.03
Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs) 14.9
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 14.85
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 14.85
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 14.84
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 14.73
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 14.73
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 14.7
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 14.7
RNA sequencing, chromatin accesibility and ChIP seq analysis of BAP1 -/- human liver organoids 14.69
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 14.67
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 14.61
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 14.61
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 14.6
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 14.55
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 14.54
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 14.53
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 14.48
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 14.42
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 14.39
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 14.37
IDH3a KO RNA-seq 14.27
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 14.27
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 14.26
Human embryonic stem cells in E8 and AKIT culture medium 14.26
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 14.25
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 14.25
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 14.21
SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis 14.18
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 14.17
Transcriptome analysis of Zika infected neural stem cells 14.17
Zika infected neural stem cells 14.17
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 14.04
BCL11B 14.02
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 14.01
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 13.88
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 13.87
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 13.86
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 13.82
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 13.79
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 13.68
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 13.64
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 13.61
RNA sequencing to compare gene expession in control and PF228-treated hepatic stellate cells 13.57
Gene Expression Profiling of SPOP Knocked Down Cell 13.57
Pharmacologic inhibition of STAT5 in AML 13.51
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 13.39
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 13.39
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 13.39
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 13.36
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 13.36
ARS2 is a general suppressor of pervasive transcription [RNAseq] 13.29
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 13.29
MOF acetyl transferase regulates transcription and respiration in mitochondria 13.27
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 13.27
Genome-wide transcriptional response to random aneuploidy in human cells 13.24
RNA sequencing of GlyH-101-treated MCF-7 cell line 13.14
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 13.12
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 13.11
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 13.11
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 13.11
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 13.11
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 13.1
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 13.09
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 13.05
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 13.05
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 13.02
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 13.01
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 12.97
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 12.96
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 12.96
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 12.95
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 12.91
Cell responses to dysregulated VZV-induced cell-cell fusion 12.88
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 12.69
BET bromodomain inhibition 12.69
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 12.64
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 12.63
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 12.57
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 12.57
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 12.5
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 12.46
LncRNA-GAS5 negative regulation of YAP-target genes expression 12.35
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 12.3
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression 12.22
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression [RNA-seq] 12.22
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 12.22
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 12.13
Generation and functional characterization of MDSC-like cells 12.03
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 11.92
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 11.89
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 11.86
Macrophage Ad5f35 M2 Challenge 11.71
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 11.63
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 11.61
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 11.56
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 11.55
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 11.55
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 11.32
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 11.18
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 11.14
Parallel T-cell cloning and deep sequencing of the transcripts of human MAIT cells reveal stable oligoclonal TCRβ repertoire 11.05
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 10.8
mRNA expression in human DAOY cells 10.79
RNA-Seq analysis of HIF-2a-responsive genes in clear-cell renal cell carcinoma 10.73
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 10.7
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 10.69
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 10.63
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 10.63
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 10.5
Regulating Interleukin-2 activity with engineered receptor signaling clamps 10.49
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation 10.45
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 10.42
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 10.31
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 10.31
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 10.24
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 10.21
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 10.19
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 10.15
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 10.1
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 10.1
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 10.01
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 10.0
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 9.9
Regulation of poly(A) tail and translation during the somatic cell cycle 9.86
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 9.73
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 9.55
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 9.53
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 9.53
KSDM1b Role in Ewing Sarcoma 9.51
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 9.46
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 9.44
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 9.4
ARID1A and ARID1B loss in HCT116 and TOV21G cells 9.35
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 9.34
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 9.3
m6A-dependent regulation of messenger RNA stability 9.14
Differentiation enhances Zika virus infection in neuronal brain cells 9.09
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 8.98
LIN28A Over-expression RNAseq 8.88
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 8.71
An siRNA screen identifies CHD4 as a target for epigenetic therapy 8.71
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 8.46
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 8.42
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 8.4
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 8.39
RNA-Seq in neutrophils from Antiphospholipid Syndrome 8.36
ChIP-seq and RNA-Seq analyses of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 8.34
RNA-Seq comparisons of gene expression profiles of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 8.34
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 8.34
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 8.22
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 8.17
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 8.15
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 8.07
RNA polymerase in pre-B-ALL cell lines 7.96
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 7.89
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 7.81
Dermal endothelial cells of type 2 diabetic patients 7.76
Splicing and epigenetic factors jointly regulate epidermal differentiation 7.74
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 7.74
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 7.63
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 7.63
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 7.61
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 7.57
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 7.57
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 7.47
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 7.35
Global expression profiles in cardiac progenitor cells generated by ISX-9 7.34
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 7.34
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 7.3
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 7.27
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 7.15
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 7.15
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 7.1
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 6.94
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 6.86
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 6.71
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 6.7
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 6.68
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 6.66
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 6.66
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 6.65
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 6.65
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 6.65
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 6.63
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 6.54
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 6.51
Ectoderm specification of H1 human embryonic stem cells 6.48
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 6.48
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 6.48
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 6.45
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 6.42
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation 6.39
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 6.32
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 5.9
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 5.87
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 5.75
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 5.73
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 5.71
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 5.68
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 5.6
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 5.55
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 5.55
RNA-seq analysis of gene expression patterns during hESC neural differentiation 5.45
hESC neural differentiation 5.45
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 5.39
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 5.39
scRNASeq analysis of cycling cardiomyocytes 5.3
RNA-Sequencing of HepG2 cells treated with TGFBeta 5.18
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 5.18
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 5.18
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 4.87
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 4.77
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 4.7
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 4.7
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 4.53
The transcriptomic landscape of MAIT cell development in the thymus (C006 RNAseq data set) 4.4
The role of m6A/m-RNA methylation in stress response regulation 4.39
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 4.39
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 4.37
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 4.37
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 4.3
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 4.3
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in Chronic Lymphocytic Leukemia 4.22
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 4.03
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 3.97
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs 3.95
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs [RNA-seq] 3.95
Transcriptome profiling of Cryptosporidium parvum infected lung and intestinal organoids 3.92
Random mono-allelic expression in MECP2-mutated cells 3.8
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 3.79
RNA-sequencing analysis examining how the Vibrio cholerae MARTX toxin and its inidividual effector domains modulate the transcriptome of human intestinal epithelial cells. 3.76
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 3.73
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 3.72
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 3.71
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 3.65
A novel target of EZH1/2 for treatment of mantle cell lymphoma 3.59
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 3.58
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 3.56
STX4 Over-Expression in Human islets 3.54
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 3.51
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 3.51
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 3.5
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 3.49
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 3.47
Mutational landscape of splicing genes and functional consequences across 33 cancer types 3.44
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 3.36
Differential responses of human fetal brain neural stem cells to Zika virus infection 3.34
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 3.31
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 3.31
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 3.22
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 3.2
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 3.2
p63 controls the enhancer landscape during keratinocyte differentiation 3.12
SRSF1 role in cellular gene expression and splicing 3.05
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 3.03
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 2.91
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 2.7
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 2.69
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 2.68
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 2.65
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 2.63
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 2.62
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 2.47
Comparative Analysis of Cas9 Activators Across Multiple Species 2.38
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 2.32
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 2.24
RNA-sequencing of healthy human skeletal myocytes 2.21
Profiling of escape kinetics of viruses subjected to RNAi 2.14
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 2.12
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 2.09
Effect of FGF13 depletion on the H460 cell line 2.07
Transcriptomes in healthy and CHB fetal hearts 2.07
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 1.99
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 1.94
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 1.94
Enhancer activation during EGF response 1.92
Targeting MTHFD2 in Acute Myeloid Leukemia 1.9
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 1.71
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 1.68
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 1.68
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 1.67
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 1.55
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 1.51
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 1.44
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 1.38
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 1.31
Transcriptional changes in lymphoma cells induced by LSD1 depletion 1.31
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 1.31
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 1.24
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 1.22
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 1.05
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 0.99
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 0.96
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 0.88
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 0.87
Trans-differentiation of human adult peripheral blood T cells into neurons 0.8
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 0.79
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.78
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 0.77
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 0.69
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 0.65
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 0.65
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 0.59
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 0.59
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 0.58
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 0.47
miRNAs affected by antagomiR-17 treatment 0.41
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 0.39
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 0.24
The role of the Calcium-Sensing receptor in colorectal cancer 0.23
Regulatory network controlling tumor-promoting inflammation in human cancers 0.18
Regulatory network controlling tumor-promoting inflammation in human cancers [RNA-seq] 0.18
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 0.18
RNA Sequencing of Human iPS derived Cardiomyocytes 0.12
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.11
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.11
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 0.08
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 0.04
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 0.03
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 0.01


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation