Gene Query: HEATR3

Dataset Description Geneva Score
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 21.4
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 21.4
Total RNA-seq in ALL-SIL upon JQ1 inhibition 21.1
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 13.68
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 13.32
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 12.85
Global gene expression profile of dasatinib-resistant RCH-ACV cells 11.51
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 10.98
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 10.49
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 10.45
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 10.45
RNAseq Analysis in glioblastoma cells treated with Mepazine 10.08
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 10.05
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 9.97
Low-Cell-Number, Single-Tube Amplification (STA) of RNAs Revealed miRNA Changes from Pluripotency to Endothelium 9.94
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 9.94
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 9.83
MeRIP-seq for heat shock in B-cell lymphoma cells 9.8
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 9.0
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 9.0
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 8.74
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 8.45
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 8.39
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 8.39
LNCaP treated with iBET 7.85
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 7.74
Developmental stage specific chromosome architecture in human erythroid cells 7.67
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 7.67
Transcriptomes of human monocytes and monocyte-derived macrophages with or without glucocorticoid treatment 7.51
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 7.5
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 7.44
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 7.35
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 7.3
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 7.26
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 7.02
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 6.96
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 6.96
Systematic discovery of endogenous human ribonucleoprotein complexes 6.62
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 6.58
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 6.55
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 6.54
Patient-derived luminal breast cancer xenografts with progestins 6.54
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 6.52
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 6.51
Effect of FGF13 depletion on the H460 cell line 6.51
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 6.46
Identification of Sin3B regulated genes during quiescence 6.31
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 6.26
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 6.25
RNA-seq of YB5 cells treated with Proscillaridin A 6.25
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 6.23
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 6.16
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 6.16
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 6.13
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 6.05
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 6.05
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 6.03
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 6.03
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 6.02
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 6.02
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 5.86
DART-seq: an antibody-free method for global m6A detection 5.76
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 5.58
RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma 5.57
Transcription elongation factors are in vivo-specific cancer dependencies in glioma 5.57
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 5.55
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 5.55
Gene expression in PANC1 cells treated with Rakicidin 5.52
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 5.41
R430: A potent inbibitor of DNA and RNA viruses 5.4
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 5.4
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 5.4
MYC dependent mRNA translation shapes gene expression and cell biology 5.25
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 5.24
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.23
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 5.18
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 5.17
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 5.14
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 5.12
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 5.11
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 5.01
RNAseq Study in CC-671 Treated Cal-51 Cells 4.92
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 4.9
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 4.9
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 4.88
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 4.88
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 4.75
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 4.73
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 4.73
Cellular response to hepatitis E virus (HEV) infection 4.69
TGF-β regulation of miRNA expression in pancreatic cancer 4.65
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 4.63
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 4.63
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 4.62
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 4.62
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 4.58
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 4.52
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 4.51
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 4.47
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 4.44
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 4.39
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 4.34
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 4.34
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 4.27
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 4.27
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 4.27
Regulation of protein translation during mitosis 4.26
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 4.25
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 4.25
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 4.24
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 4.24
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 4.22
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 4.17
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 4.16
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate. 4.14
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 4.14
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 4.14
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 4.13
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 4.12
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 4.12
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 4.12
Transcriptome Profiling of Human Primary Monocytes 4.12
Integrating single-cell transcriptomic data across different conditions, technologies, and species 4.12
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 4.07
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 4.05
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 4.05
Endothelial gene expression analysis 4.03
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 4.03
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 4.02
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 4.02
Loss of CREBBP results in gene expression repression in lymphoma cells 4.02
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 4.0
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 4.0
TGF-β promotes genomic instability after loss of RUNX3 3.95
Effect of PRDM11 depletion in U2932 cells 3.95
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 3.94
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 3.94
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 3.93
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 3.9
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 3.89
Tracking distinct RNA populations using efficient and reversible covalent chemistry 3.87
Mapping interactions for the TNIP2 hub protein 3.84
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 3.83
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 3.82
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 3.81
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 3.79
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 3.77
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 3.74
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 3.72
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 3.71
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 3.69
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 3.66
A transcriptome-wide divergence in protein translation scales with LIN28B expression 3.66
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 3.65
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 3.63
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 3.63
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 3.63
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 3.62
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 3.61
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 3.61
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 3.6
ETV7 and interferon response 3.6
NAPRT activation of macrophages 3.59
quanTIseq: quantifying immune contexture of human tumors 3.56
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 3.55
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 3.55
Global analysis of alternative splicing regulated by RBM10 3.55
Integrin signaling regulates YAP/TAZ to control skin homeostasis 3.54
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 3.54
Transcriptomes of human monocytes after ex vivo exposure to uric acid 3.54
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 3.54
The landscape of alternative splicing in aggressive prostate cancers 3.5
Tracking of dCas9-methyltransferase footprints 3.45
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 3.43
RNA expression analysis upon JMJD1C depletion 3.43
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 3.42
Hijacking of stress response machinery by oncogenes in acute leukaemia 3.42
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 3.39
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 3.38
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 3.38
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 3.36
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 3.36
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 3.36
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 3.35
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 3.35
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 3.35
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 3.33
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 3.33
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 3.33
Interleukin-1β induces mitochondrial DAMP production to activate STING-dependent innate immune programs 3.32
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 3.31
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 3.3
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 3.29
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 3.29
Seletive inhibition of CDK9 in DLBCL cell lines 3.26
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 3.25
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 3.25
METTL3 and WTAP 3.24
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 3.22
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 3.22
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 3.22
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 3.22
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 3.22
TCF7L1 knockdown in pancreatic cancer 3.18
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 3.17
RNA-seq of tumor cells following angiopellosis extravasation 3.16
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 3.14
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 3.13
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 3.13
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 3.12
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 3.1
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 3.09
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 3.09
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 3.09
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 3.09
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 3.05
Human cells contain natural double-stranded RNAs with potential regulatory capacity 3.04
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 3.03
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 3.03
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 2.99
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 2.98
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 2.98
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 2.98
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 2.98
Effect of mitochondria deficiency on senescence-associated gene expression 2.97
Transcriptome analysis of U87 cells upon LINC00152 knockdown 2.96
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 2.96
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 2.93
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 2.92
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 2.92
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 2.92
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 2.91
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 2.91
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 2.91
Mutational landscape of splicing genes and functional consequences across 33 cancer types 2.91
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 2.87
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 2.87
RNA-Sequencing of HepG2 cells treated with TGFBeta 2.86
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 2.83
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 2.81
SLIGRL-induced gene expression changes in NHEK cells 2.81
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 2.81
RNA-seq of stable and unstable section of human atherosclerotic plaques 2.8
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 2.79
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 2.79
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 2.79
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 2.79
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 2.78
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 2.76
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 2.75
Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons 2.73
Irf9 function in immunity in mouse 2.73
Transcriptome analysis of SKI knock-out in HL60 cells 2.73
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 2.73
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 2.72
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 2.7
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 2.69
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 2.67
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 2.66
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 2.66
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 2.66
Global Mapping of Human RNA-RNA Interactions 2.61
High-throughput sequencing of PROMPT-enriched samples. 2.6
KSDM1b Role in Ewing Sarcoma 2.6
RNA polymerase in pre-B-ALL cell lines 2.56
Functional significance of the HIV-1 Tat signature amino acid residues 2.56
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 2.56
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 2.54
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 2.53
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 2.51
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 2.5
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 2.48
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 2.46
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 2.45
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 2.44
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 2.44
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 2.43
MYOD Remodeling of the Genome Architecture during Myogenic Conversion of Somatic Cells 2.41
RNA-sequencing of bulk CD19+ Thymic B cells from young (3 month - 4 year) and old (42 - 61 years) humans 2.41
RNA-sequencing of bulk CD19+ Thymic B cells from mice and humans 2.41
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 2.4
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 2.39
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 2.38
Transcriptome analysis upon C6orf203 silencing 2.38
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 2.38
oxLDL exposed trained monocytes 2.37
Transcriptomes of oxLDL exposed trained monocytes 2.37
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 2.37
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.36
Cajal bodies are linked to genome conformation 2.35
Cajal bodies are linked to genome conformation [RNA-Seq] 2.35
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 2.33
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 2.33
MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts 2.32
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 2.32
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 2.32
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 2.31
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 2.31
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 2.31
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 2.31
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 2.29
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 2.28
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 2.28
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 2.28
Gene expression in GBM with Cav3.2 inhibition 2.27
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 2.26
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 2.26
Re-Wiring 3D Nuclear Architecture by a Single Transcription Factor during Somatic Cell Reprogramming 2.25
Identification of monocyte-like precursors of granulocytes as a mechanism for accumulation of PMN-MDSC in cancer 2.22
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 2.22
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 2.13
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 2.12
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 2.12
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 2.08
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia 2.06
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 2.06
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 2.05
RNA sequencing data of whole blood cells of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women 2.05
Epigenetic reprogramming of melanoma cells by vitamin C treatment 2.03
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 2.01
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.0
Effect of drugs on transcriptomic profiles 1.99
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 1.98
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 1.98
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 1.96
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 1.96
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 1.96
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 1.95
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 1.95
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 1.94
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 1.93
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 1.92
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 1.9
single cell RNA-seq from GM12878 (ENCSR673UIY) 1.88
Mitochondrial dsRNA triggers antiviral signalling in humans 1.87
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 1.86
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 1.86
Oncogenic MYC induces a dependency on the spliceosome in human cancer 1.85
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 1.85
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 1.84
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 1.84
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 1.83
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 1.78
Transcriptome landscape of HeLa response upon triamcinolone acetonide 1.78
Diarrhea in lymphocytic colitis: ERK1/2-dependent ENaC dysregulation and claudin-4-, -5- and -8-related barrier defects 1.76
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 1.76
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 1.74
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 1.74
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 1.74
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 1.74
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 1.74
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 1.74
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 1.73
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 1.73
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 1.68
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.66
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 1.62
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 1.61
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 1.59
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 1.58
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 1.58
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.54
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 1.53
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 1.52
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 1.5
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 1.48
Gene expression changes due to PARP knockdown in human cells 1.46
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 1.46
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 1.43
JAK dependent survival of ALK- ALCL 1.43
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 1.41
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 1.36
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 1.36
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.35
Hypoxic transcriptome of SQ20B human head and neck cancer cells 1.34
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 1.31
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.31
Identification of long noncoding RNAs regulated by p53 1.31
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 1.31
Modulation of nonsense-mediated decay by rapamycin 1.29
Ribosomal protein RPL26 is the principal target of UFMylation 1.29
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 1.29
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 1.27
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 1.25
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 1.22
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 1.22
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 1.2
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 1.2
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 1.19
A20 regulates canonical wnt-signaling through an interaction with RIPK4 1.18
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 1.15
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 1.13
Macrophage Ad5f35 PhenoMap 1.13
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 1.12
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 1.12
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 1.12
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 1.1
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 1.08
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 1.08
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 1.07
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 1.04
N6-methyladenosine (m6A) profiling of EndoC-bH1 cell line and RNA seq of Mettl14 knockout mice beta cell 1.04
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 1.04
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 0.95
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 0.95
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.95
Controlling for gene expression changes in transcription factor protein networks. 0.93
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 0.93
Transposon-based construction of strand-specific RNA-seq libraries 0.93
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 0.93
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 0.91
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.9
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 0.88
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 0.87
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 0.87
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 0.8
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 0.78
Expression and functions of long noncoding RNAs during human T helper cell differentiation 0.76
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 0.76
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 0.75
Modeling Human Cancer-induced Cachexia (Human) 0.75
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.74
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.74
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.74
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 0.71
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 0.71
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 0.71
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 0.7
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 0.67
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 0.66
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 0.65
Dysregulated immune system networks in war veterans with PTSD 0.64
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 0.63
Transcriptomic analysis of ERR alpha orphan nuclear receptor 0.63
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 0.58
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.57
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.57
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.57
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 0.57
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 0.57
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 0.56
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 0.55
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 0.51
An optimization system for isolating and sequencing of single human colon cancer cells 0.5
The bromodomain protein BRD4 regulates splicing during heat shock 0.49
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 0.47
Genome-wide analysis of the Integrator complex (HTS) 0.46
Genome-wide analysis of the Integrator complex 0.46
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.46
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.46
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.45
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 0.44
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.43
Leucegene: AML sequencing (part 6) 0.42
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.41
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.4
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.39
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.39
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 0.37
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 0.37
Non-inflammatory tumor microenvironment of Diffuse Intrinsic Pontine Glioma (DIPG) 0.36
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 0.36
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 0.34
Single-cell ID-seq identifies BMP signaling as a driver of a late stage epidermal differentiation program. 0.33
Effect of BMP inhibition or stimulation of primary human keratinocytes 0.33
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.33
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.27
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 0.27
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.25
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.25
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 0.25
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 0.24
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 0.23
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 0.22
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.21
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.21
Transcriptomic analysis of human macrophages in 3D 0.21
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 0.2
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 0.2
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 0.19
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 0.19
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.19
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 0.19
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.17
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.17
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.17
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.16
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.15
Genome-wide mapping of TEL-AML1 targets in acute leukemia 0.14
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.14
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 0.13
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.13
Transcriptome analysis of peripheral blood monocytes 0.1
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.09
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.08
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.07
Transcriptome profiling of A2M treated A549 Cell Line Samples 0.07
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.02
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.02
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.01


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