Gene Query: HIRA

Dataset Description Geneva Score
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 34.22
Spliceosomal disruption of the non-canonical BAF complex in cancer 24.09
The effect of PPARG inhibition on human angiomyolipoma cells 22.31
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 20.99
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 19.83
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 18.16
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 17.4
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 17.4
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 16.81
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 16.64
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 16.0
DART-seq: an antibody-free method for global m6A detection 15.63
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 14.84
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 14.73
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 14.34
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 14.13
METTL3 promotes translation in human cancer cells 14.08
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 13.6
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 13.27
SRSF2 mutations impair hematopoiesis and alter exon recognition 13.15
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 12.52
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 12.29
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 11.83
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 11.7
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 11.46
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization 11.29
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization [RNA-Seq] 11.29
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 11.08
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 11.06
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 11.0
Transcriptomic analysis of LSD1 10.76
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 10.75
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 10.64
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 10.63
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 10.58
Seletive inhibition of CDK9 in DLBCL cell lines 10.52
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 10.5
Differential gene expression of human melanoma cells [RNA-seq] 10.5
Macrophage Ad5f35 M2 Challenge 10.48
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 10.36
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 10.33
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 10.32
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 10.3
RNA transcriptome analysis during HSV-1 infection 10.25
RNA-seq analysis of RALD iPSCs after in vitro differentiation 10.15
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 10.12
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 9.9
Effects of rFVIIIFc on human macrophages 9.83
CD86 regulates a pro-survival signal in myeloma cells 9.65
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 9.56
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 9.56
RNA-seq of naive and primed ES cells (NHSM) 9.54
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 9.54
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 9.33
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 9.32
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 9.2
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 9.2
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 9.16
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 9.15
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 9.05
High-throughput sequencing of pluripotent cells 9.04
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 9.03
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 9.03
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 9.02
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq] 8.87
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia 8.87
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 8.75
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 8.61
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 8.54
Mapping interactions for the TNIP2 hub protein 8.45
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 8.42
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 8.37
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 8.3
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 8.27
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 8.21
Region-specific Innate Antiviral Responses of the Human Epididymis 8.07
mRNA recovered upon RNF219 IP. [RNA-IP] 7.95
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 7.95
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy 7.91
Gene expression profile of multiple myeloma cell lines treated with CB-5083 7.86
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 7.81
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 7.8
The pause-initiation limit restricts transcription activation in human cells 7.79
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 7.78
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 7.75
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 7.75
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 7.74
CDK12 mediated transcriptional regulation in U2OS cells 7.63
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 7.6
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 7.57
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 7.5
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 7.44
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 7.44
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 7.43
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 7.42
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 7.34
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 7.34
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 7.29
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 7.27
Viral infection enhances NK cell activation via Type I dependent pathways and can be utilized to enhance influenza-specific monoclonal antibody therapies 7.26
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 7.25
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 7.21
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 7.21
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 7.2
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 7.13
Short and Long RNA sequencing of human mature erythrocytes 7.13
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 7.12
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 7.09
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 7.05
Differentially expressed vascular development genes for iPSC-ECs from CDI 7.04
The effect of insulin on mRNA transcription of human pluripotent stem cells 7.02
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 7.01
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 6.96
RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-kB-dependent inflammation 6.95
JunB control of keratinocyte-mediated inflammation [RNA-seq] 6.95
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 6.94
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 6.93
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 6.93
Conservative alteration of chromosomal expression pattern across human solid tumor types 6.92
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 6.9
Transcriptome analysis of U87 cells upon LINC00152 knockdown 6.89
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 6.8
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 6.79
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 6.77
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 6.73
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 6.73
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 6.7
Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury 6.65
Knockdown of ADNP in HCT116 colon cancer cells 6.65
The interplay between SOX4 and SMAD3 in the context of breast cancer 6.64
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 6.63
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 6.61
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 6.61
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 6.53
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 6.51
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 6.48
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 6.46
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 6.46
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 6.45
Gene expression analysis of the impact of TDP-43 knockout in human cells. 6.42
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 6.37
Downregulation of DDX5/DDX17 and REST 6.36
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 6.36
The landscape of alternative splicing in aggressive prostate cancers 6.35
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 6.34
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 6.32
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 6.32
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 6.31
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 6.27
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 6.26
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 6.26
Gene expression changes after LOC550643 silencing 6.25
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 6.23
Transcriptomic analyssis following EHMT1/2 inhibition 6.23
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 6.22
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 6.21
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 6.21
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing 6.2
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing [RNA-seq] 6.2
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 6.19
PTHrP overexpression in MCF7 cells 6.18
Genome-wide discovery of human splicing branchpoints [RNAse] 6.12
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 6.11
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 6.11
GCTM-5 positive and negative cells in pancreatic adenocarcinoma cell lines 6.1
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 6.09
HNF1A deficiency impairs β-cell fate, granule maturation and function 6.08
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 6.06
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 6.04
Accurate annotation of human protein-coding small open reading frames 6.04
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 6.02
EWSR1 influences alternative splicing through direct and indirect mechanisms 6.0
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 5.99
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 5.87
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 5.82
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.79
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 5.78
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 5.76
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 5.76
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 5.74
Dynamic 3D chromosomal landscapes in acute leukemia 5.73
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 5.73
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 5.72
Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells 5.69
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 5.69
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 5.65
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 5.65
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. 5.63
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 5.61
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 5.61
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 5.6
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 5.6
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 5.57
Genome-wide discovery of human splicing branchpoints 5.55
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 5.55
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 5.55
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 5.51
Transcriptome-wide identification of CELF2 functional targets in T cells 5.51
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 5.48
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 5.48
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 5.45
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 5.44
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 5.4
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 5.4
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 5.39
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 5.38
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 5.37
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 5.37
RNAseq analysis of the human neutrophil transcriptome, with and without in vitro cytokine stimulation 5.36
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 5.36
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 5.35
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 5.35
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 5.35
Effect of drugs on transcriptomic profiles 5.31
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 5.28
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 5.28
Comparative Analysis of Cas9 Activators Across Multiple Species 5.27
RNA-seq analysis to identify the genes regulated by p53-SET interplay 5.22
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 5.21
Macrophage Ad5f35 PhenoMap 5.2
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 5.18
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 5.18
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 5.16
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 5.14
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 5.13
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 5.08
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 5.06
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 5.06
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 5.04
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 5.03
SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis 5.02
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 5.02
A role for ZNF598 in post-transcriptional gene regulation 5.02
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 5.02
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 5.01
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 5.0
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 4.99
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 4.96
NKX2.2 4.96
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 4.93
RNA-seq of YB5 cells treated with Proscillaridin A 4.92
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 4.92
Effect of PBK knockdown on C4-2 cell transcriptome 4.92
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 4.89
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 4.89
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 4.89
Capturing the Interactome of Newly Transcribed RNA 4.84
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.84
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 4.84
A Unique Epigenomic Landscape Defines Human Erythropoiesis 4.84
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 4.84
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 4.83
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 4.82
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 4.8
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 4.78
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 4.77
Gene expressions of H9s in different culture systems 4.75
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 4.73
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 4.73
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 4.71
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 4.7
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 4.68
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 4.68
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 4.67
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 4.67
CD73 knockdown effect in pancreatic cancer cell lines 4.65
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 4.64
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 4.6
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 4.56
Next generation sequencing on knockdown of AC093323.3 in lung cancer cells 4.55
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 4.54
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 4.51
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 4.49
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 4.49
Functional role of CPPED1 in trophoblasts. 4.47
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 4.46
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 4.46
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 4.41
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 4.4
RNA sequencing of human pancreatic cancer cell lines 4.38
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 4.34
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 4.32
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 4.32
Nucleoporin-mediated regulation of cell identity genes 4.3
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 4.27
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 4.27
SNHG5 siRNA knock down in HCT116 cells 4.25
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 4.24
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 4.17
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 4.17
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 4.17
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 4.17
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 4.16
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 4.1
Searching for target genes of miR-508/509/506/514 in HCT116 cells 4.09
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 4.06
NHLRC1 re-expression in cancer cells 4.06
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 4.03
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 4.0
METTL3 and WTAP 3.97
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 3.97
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 3.97
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 3.96
Gene expression profiling of papillary thyroid cancer from central and invasive regions 3.95
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 3.94
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 3.92
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 3.9
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 3.89
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 3.89
ETV7 and interferon response 3.89
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 3.83
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 3.83
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 3.82
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 3.82
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 3.8
Regulation of poly(A) tail and translation during the somatic cell cycle 3.79
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 3.76
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 3.76
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 3.75
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 3.75
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 3.71
Global analyses of the effect of different cellular contexts on microRNA targeting 3.71
Illumina Total RNA-seq in HeLa 3.71
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 3.69
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 3.66
Expression data from miR340 overexpressing human A549 cells 3.65
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 3.6
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 3.51
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 3.5
Trnascriptome analysis of HeLa cells infected with rTHOV-wt, -dML, -SW mutant or mock-treated 3.45
Organoids derived from directly reprogrammed human hepatocytes for modeling liver cancer initiation 3.43
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 3.4
Hijacking of stress response machinery by oncogenes in acute leukaemia 3.37
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 3.37
HEK293 TFAM Knockout Expression Study 3.36
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 3.36
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 3.35
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 3.33
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 3.29
Tracing Enhancer Networks using Epigenetic Traits (TENET) 3.24
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 3.19
Hepatitis C virus functionally sequesters miR-122 3.17
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 3.17
Genome-wide identification of cancer-specific alternative splicing in circRNA 3.15
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 3.14
BCL11B 3.13
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 3.09
The circadian transcriptional landscape in primary human mammary epithelial cells 3.07
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 3.07
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 3.03
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 3.03
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 3.02
Loss of CREBBP results in gene expression repression in lymphoma cells 3.02
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 3.02
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 2.93
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 2.9
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 2.88
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway 2.86
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 2.86
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 2.84
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 2.84
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 2.83
Tpl-2 small molecule project 2.78
Tpl-2 and MEK small molecule inhibitors 2.78
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 2.75
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 2.74
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 2.64
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 2.64
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 2.56
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 2.53
RNA splicing alteration on glioblastoma and normal neural stem cells 2.5
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 2.49
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 2.43
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 2.43
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 2.43
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 2.43
The bromodomain protein BRD4 regulates splicing during heat shock 2.42
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 2.4
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 2.38
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 2.38
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 2.35
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 2.29
Transcriptomic analysis of human coronary artery endothelial cells stimulated with TNF-alpha in the presence and absence of ACSL3 siRNA 2.28
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding 2.28
Tracking distinct RNA populations using efficient and reversible covalent chemistry 2.26
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 2.23
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 2.2
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 2.18
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 2.18
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 2.18
Transcriptional profiling of LS1034 cells treated with tepoxalin 2.16
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 2.16
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 2.14
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 2.13
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 2.11
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 2.03
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 2.01
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.97
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 1.95
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.94
RNA editing in nascent RNA affects pre-mRNA splicing 1.92
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 1.91
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 1.9
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 1.9
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 1.82
Global response to chemotherapy-induced apoptosis 1.82
Specific molecular signatures underlie response to decitabine in CMML 1.79
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 1.79
Impact on erythroid progenitor type on erythroid differntiation 1.79
Comprehensive comparative analysis of 5’ end RNA sequencing methods 1.76
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 1.74
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 1.74
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 1.73
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 1.73
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 1.67
Gene expression changes in HSV-1 infected HeLa cells with knockdown of B2M 1.66
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.62
Characterization of parental and rociletinib-resistant derived H1975 cell lines 1.6
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 1.59
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 1.59
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 1.58
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.52
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.52
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 1.52
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 1.5
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 1.47
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 1.45
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 1.45
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 1.44
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 1.44
Solid phase chemistry to covalently and reversibly capture thiolated RNA 1.44
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 1.39
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 1.39
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 1.35
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 1.32
RNA sequencing of T-ALL (COG study) 1.32
Analyses of T-ALL (COG study) 1.32
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 1.27
Defective structural RNA processing in relapsing-remitting multiple sclerosis 1.23
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.22
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.22
Neutrophils RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 1.17
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 1.13
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 1.13
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 1.12
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 1.12
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 1.12
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 1.11
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 1.1
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 1.09
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 1.08
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 1.07
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.04
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.04
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 1.03
miR941 overexpression experiment 0.99
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.97
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.93
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 0.91
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 0.91
Function and hormonal regulation of GATA3 in human first trimester placentation 0.91
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 0.84
RNA seq analysis of human Fetal and adult derived Enterospheres 0.81
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 0.75
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 0.74
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.72
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.71
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 0.69
Induced DNA demethylation, genome instability and transcription 0.69
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.69
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 0.68
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 0.68
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 0.67
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 0.66
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 0.64
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 0.63
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 0.6
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 0.59
Ribosomal protein RPL26 is the principal target of UFMylation 0.58
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 0.54
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.43
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.28
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 0.28
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 0.27
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 0.24
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.22
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 0.22
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 0.2
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 0.15
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.14
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.11
Myc activation coordinates gene transcription and protein translation responses 0.1
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.06
Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs) 0.06
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.05
Expression analysis of the TAF1 syndrome 0.04
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.03
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.02
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.0
The role of m6A/m-RNA methylation in stress response regulation 0.0


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