Gene Query: HMMR

Dataset Description Geneva Score
Genome-wide transcriptional response to random aneuploidy in human cells 110.77
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 103.89
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 102.24
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 95.47
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 85.47
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 80.96
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 74.39
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 70.11
The regulartory role of ZCCHC24 in splicing machinery 68.31
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 67.47
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 65.49
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 65.49
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 64.9
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 60.5
Altering cancer transcriptomes using epigenomic inhibitors 60.5
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 55.54
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 55.54
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 54.15
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 52.75
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 51.4
Role for citron kinase in prostate cancer growth 47.71
scRNASeq analysis of cycling cardiomyocytes 47.54
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 47.43
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 43.38
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 43.29
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 42.91
Paxillin regulates genomic networks in prostate cancer [LNCaP] 42.9
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 42.84
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 42.51
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 41.94
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 41.19
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation 38.59
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 38.11
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 38.02
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 37.31
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 35.15
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 34.76
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 34.0
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 33.96
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 33.91
RNA-seq analysis of Retinoic Acid and Non-treated Control hiPSCs 33.6
Transcriptional profiles of normal human mature B cells 33.55
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 33.45
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 33.25
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 33.24
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 33.24
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 33.16
Total RNA-seq in ALL-SIL upon TLX1 knockdown 32.67
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 32.6
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 32.39
RNA-seq of resting and activated CD4+ T cells +-JQ1 32.01
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 31.48
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 31.48
Total RNA-seq in ALL-SIL upon JQ1 inhibition 31.46
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 31.38
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 30.93
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 30.93
RNAseq Study in CC-671 Treated Cal-51 Cells 30.76
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 30.67
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 30.61
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation 30.44
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq) 30.44
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 30.41
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 30.4
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 30.38
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 30.12
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 30.12
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 30.1
Gene expression in PANC1 cells treated with Rakicidin 29.94
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 29.8
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 29.48
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 28.04
Effect of CHKA knockdown on C4-2 cell transcriptome 27.99
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 27.86
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 27.6
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 27.58
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 27.55
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 27.26
HNRNPM-regulated splicing dependencies in prostate cancer 27.26
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 27.26
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 27.05
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 27.03
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 27.03
A sister of NANOG regulates genes expressed in pre-implantation human development 27.02
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 26.76
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 26.56
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 26.25
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 26.04
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 26.04
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 25.61
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 25.61
Identification of HOXB13 target genes responsive to BET inhibitors 25.61
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 25.38
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 25.16
A Unique Epigenomic Landscape Defines Human Erythropoiesis 25.16
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 25.16
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 25.01
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 24.86
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 23.93
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 23.82
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 23.82
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 23.71
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 23.62
Expression profiling of etoposide-induced senescent cells 23.39
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 23.21
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 22.89
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 22.83
Transcription control by the ENL YEATS domain in acute leukemia 22.83
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 22.79
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 22.76
MYCi361 regulates MYC target genes 22.69
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 22.52
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 22.52
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 22.41
Expression level comparison under dividing and quiescent states in human primary fibroblasts 22.39
Differentially expressed genes post knock down of lincDUSP26 22.35
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 22.3
Effect of Influenza virus infection on lncRNA expression in A549 cells 21.97
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 21.96
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 21.85
Inhibition of TNBC metastasis by Gpx1 21.77
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 21.72
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 21.6
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 21.57
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 21.57
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 21.48
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 21.47
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 21.44
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 21.44
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 21.38
Transcriptomic analyssis following EHMT1/2 inhibition 21.26
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 21.12
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 21.07
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 20.9
Human cell line and subcutaneous tumor 20.8
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 20.63
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 20.63
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 20.53
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 20.51
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 20.37
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 20.37
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 20.37
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 20.21
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 20.15
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 20.14
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 20.13
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 20.12
Neurofibroma 20.07
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 20.07
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 19.87
G-quadruplex structures mark human regulatory chromatin 19.7
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 19.65
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 19.65
Transcriptional profiling of LS1034 cells treated with tepoxalin 19.63
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 19.62
RNA-seq profiling identifies Androgen Receptor-regulated genes in prostate cancer cells 19.61
Androgen Receptor-regulated genes in prostate cancer cells 19.61
Functional role of SLIT2 and ROBO1 in trophoblasts 19.6
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 19.47
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 19.44
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 19.43
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 19.34
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 19.33
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 19.28
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 19.19
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 19.14
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 19.04
Widespread intronic polyadenylation diversifies immune cell transcriptomes 18.9
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 18.86
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 18.72
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 18.72
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 18.67
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 18.67
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 18.66
Characterization of parental and rociletinib-resistant derived H1975 cell lines 18.52
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 18.22
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 18.16
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 18.16
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 18.09
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 17.89
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 17.82
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 17.79
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 17.79
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 17.72
RNA sequencing of GlyH-101-treated MCF-7 cell line 17.72
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 17.69
Knockdown of ADNP in HCT116 colon cancer cells 17.64
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 17.63
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 17.57
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 17.56
Identification of global regulators of T-helper cell lineage specification 17.56
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 17.52
The landscape of alternative splicing in aggressive prostate cancers 17.41
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 17.4
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 17.39
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 17.32
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 17.28
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 17.17
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 17.04
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 16.72
Analysis of transcriptional regulation by Myt1 and Myt1l 16.6
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 16.39
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 16.33
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 16.3
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 16.13
Overexpression and knockdown experiment for circCSNK1G3 16.08
Genes significantly down or Up-regulated upon RNF219 knockdown 15.98
Illumina Total RNA-seq in HeLa 15.95
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 15.91
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 15.9
Peptidomimetic blockade of MYB in acute myeloid leukemia 15.9
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 15.89
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 15.85
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 15.84
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 15.71
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 15.63
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 15.58
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 15.53
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 15.52
Global Mapping of Human RNA-RNA Interactions 15.47
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 15.42
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 15.34
Effect of from Human Umbilical Vein Endothelial Cells 15.31
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 15.13
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 15.09
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 15.09
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 14.99
A549 cells and MSR-A549 cells 14.99
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 14.98
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 14.98
LncRNA-GAS5 negative regulation of YAP-target genes expression 14.96
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 14.91
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 14.88
Disruption of the exocyst induces podocyte loss and dysfunction 14.77
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 14.69
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 14.68
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 14.55
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 14.54
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 14.51
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 14.51
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 14.49
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 14.49
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 14.38
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 14.33
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 14.33
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 14.32
Overexpression of NFIB and YBX1 in MCF-7 cells 14.31
Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes 14.31
The effect of PPARG inhibition on human angiomyolipoma cells 14.28
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 14.26
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 14.23
Gene expression analysis of immortalized human liver progenitor-like cells in culture 14.22
Canonical and non-canonical regulatory roles of androgen receptor variant 7 in prostate cancer 14.2
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 14.16
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 14.16
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 14.12
Transcriptional responses of human insulinoma cells to acute cytokine exposure 14.12
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 14.09
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 14.03
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 13.97
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 13.97
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 13.95
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 13.94
The contribution of Alu exons to the human proteome 13.94
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 13.85
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 13.85
Co-regulation of splicing by Rbfox1 and hnRNP M 13.8
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 13.8
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 13.63
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 13.6
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 13.6
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic co-culture 13.56
ARS2 is a general suppressor of pervasive transcription [RNAseq] 13.54
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 13.33
p63 controls the enhancer landscape during keratinocyte differentiation 13.27
TGF-β regulation of miRNA expression in pancreatic cancer 13.22
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 13.2
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 13.12
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 13.1
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 13.1
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 13.1
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 13.08
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 13.0
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 12.98
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 12.97
HEK293 TFAM Knockout Expression Study 12.9
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 12.83
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 12.83
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 12.83
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 12.76
MYCL and EP400 are required for Max and MCPyV mediated gene activation 12.58
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 12.47
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 12.47
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 12.47
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 12.46
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 12.24
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 12.13
CD73 knockdown effect in pancreatic cancer cell lines 11.97
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 11.84
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 11.81
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 11.76
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 11.76
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 11.61
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 11.55
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 11.52
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 11.52
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 11.32
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 11.19
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 11.19
High-efficiency RNA-based reprogramming of human primary fibroblasts 11.18
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 11.17
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 11.17
mRNA differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 11.1
Differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 11.1
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 11.07
Be1 and Be2 B cells are transcriptionally distinct 10.95
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 10.93
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 10.85
EWSR1 influences alternative splicing through direct and indirect mechanisms 10.82
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 10.8
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 10.7
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 10.69
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 10.52
Integrin signaling regulates YAP/TAZ to control skin homeostasis 10.42
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 10.34
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 10.29
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 10.25
A code of mono-phosphorylation modulates the function of RB. 10.17
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 10.13
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 9.87
Ro60-knockout cells 9.78
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 9.46
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 9.39
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 9.34
Differential Gene Expression between MCF10A and MCF7 cells 9.3
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 9.29
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 9.19
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 9.11
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 9.07
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 9.03
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 9.03
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 9.01
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 8.91
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 8.88
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 8.83
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 8.8
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 8.8
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 8.8
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 8.76
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 8.74
Targeting MTHFD2 in Acute Myeloid Leukemia 8.66
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 8.58
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 8.49
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 8.49
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 8.44
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 8.24
Gene expression profile of multiple myeloma cell lines treated with CB-5083 8.15
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 8.13
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 8.13
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 8.13
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 8.02
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 8.02
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 7.91
A map of gene expression in neutrophil-like cell lines 7.88
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 7.71
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 7.68
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 7.66
Bone marrow derived human B cells [normal proB] 7.64
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 7.59
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 7.58
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 7.5
Gene Expression Profiling of WT and KDM3A Knocked out Cell 7.5
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 7.48
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 7.48
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq] 7.47
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies 7.47
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 7.4
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 7.4
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 7.11
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 7.01
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 6.94
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 6.84
mRNA recovered upon RNF219 IP. [RNA-IP] 6.8
O-glcnAc reprograms cellular energetics 6.75
siRNA-mediated knockdown 6.47
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 6.31
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 6.27
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 6.25
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 6.23
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 6.15
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 6.15
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 6.07
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 6.07
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 6.05
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 6.03
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 5.9
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 5.9
Identification of long noncoding RNAs regulated by p53 5.88
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 5.78
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 5.74
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 5.74
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 5.48
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 5.22
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 5.22
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 5.21
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 5.21
Gene profiling of human adult and pediatric liver cancer cells 5.16
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 5.13
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 5.13
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 4.93
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 4.9
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 4.9
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 4.9
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 4.83
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 4.83
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 4.66
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 4.66
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 4.66
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 4.61
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 4.57
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 4.55
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 4.55
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 4.42
6mer seed toxicity in tumour suppressive microRNAs 4.39
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 4.23
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 4.23
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 4.23
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 4.16
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 4.16
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 4.09
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 4.08
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 4.08
Exogenous rescue of KLHL9 in SF210 cell line 3.81
Zika virus infection reprograms global transcription of host cells to allow sustained infection 3.8
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 3.76
RNA-Seq of PRMT1 overexpression ECA109 cells 3.76
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 3.57
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 3.47
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 3.46
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 3.44
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 3.4
Conservative alteration of chromosomal expression pattern across human solid tumor types 3.39
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 3.37
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 3.25
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 3.25
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 3.23
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 3.23
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 3.11
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 3.01
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 2.74
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 2.7
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 2.53
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 2.53
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 2.53
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 2.53
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 2.53
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 2.48
Oncogenic roles of ARID5B in T-ALL 2.43
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 2.43
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 2.4
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 2.33
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 2.27
Expression profiling of converted and control dermal BJ fibroblasts 2.27
RNA-seq analysis of control and Myc-induced U2OS cells 2.18
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 1.99
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 1.88
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 1.72
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 1.71
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 1.68
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 1.63
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 1.6
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 1.54
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 1.54
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.49
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 1.42
The cohesin release factor WAPL restricts chromatin loop extension. 1.42
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 1.39
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 1.33
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 1.31
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.22
6mer seed toxicity in viral microRNAs 1.12
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 1.12
The circadian transcriptional landscape in primary human mammary epithelial cells 1.04
Transcriptomic analysis of LSD1 1.02
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 0.93
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 0.67
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 0.64
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.62
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 0.6
SNHG5 siRNA knock down in HCT116 cells 0.57
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 0.47
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 0.47
Transcriptome-wide modulation of splicing by the exon junction complex 0.39
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 0.32
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 0.2
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 0.15
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.1
HBEC-shp53-PCHD7 0.09
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 0.06
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 0.03


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