Gene Query: IRAK4

Dataset Description Geneva Score
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 18.19
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 10.08
A sister of NANOG regulates genes expressed in pre-implantation human development 9.67
Primary human trophoblast from term placenta 8.26
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 7.76
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 7.76
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 7.58
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 7.53
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 7.52
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 7.52
Next Generation Sequencing of human SMA and healthy control Motor Neurons 7.51
Integrating single-cell transcriptomic data across different conditions, technologies, and species 7.21
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 7.19
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 7.12
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 6.8
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 6.79
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 6.79
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 6.72
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 6.67
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 6.64
Effect of CHKA knockdown on C4-2 cell transcriptome 6.54
The role of FAM46C in myeloma cells [sequencing] 6.36
The role of FAM46C in myeloma cells 6.36
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 6.16
Transcriptome Analysis of PBMCs in peripheral blood of patients with hepatocellular carcinoma 6.1
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 5.78
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 5.77
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 5.62
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 5.16
Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis 5.09
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 5.02
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 5.01
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 5.01
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 5.0
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 4.95
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 4.87
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 4.73
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 4.73
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 4.71
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 4.59
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 4.59
Be1 and Be2 B cells are transcriptionally distinct 4.54
Transcriptomic profiling of human CD34+ derived mast cells [RNA-Seq] 4.54
Landscape of human mast cell chromatin: a rich resource for identification of novel mediators and genetic drivers of allergic and inflammatory diseases 4.54
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 4.5
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 4.49
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 4.41
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 4.38
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 4.35
CROP-Seq in Primary Human T Cells 4.35
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 4.19
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 4.19
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 4.17
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 4.17
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 4.16
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 4.15
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 4.15
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 4.15
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 4.03
Short and Long RNA sequencing of human mature erythrocytes 4.02
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression 3.98
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 3.97
Intron retention induced by microsatellite expansions as a disease biomarker. 3.97
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 3.96
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 3.92
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 3.92
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 3.86
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 3.86
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 3.85
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 3.79
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 3.72
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 3.65
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 3.64
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 3.64
RNA-seq analysis of primary patient samples to characterize the CNS leukemia 3.59
Transcriptome analysis of CNS leukemia 3.59
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 3.56
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 3.53
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 3.51
The landscape of alternative splicing in aggressive prostate cancers 3.49
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 3.47
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 3.46
BACH2 in human plasma cell fate decision 3.46
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 3.42
The evolution of N6-methyladenosine in primates 3.42
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 3.41
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 3.41
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 3.39
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 3.39
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 3.38
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 3.36
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 3.36
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 3.36
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.35
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 3.35
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 3.34
Gene expression profiling of leukemia cells following asparagine depletion 3.34
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition 3.3
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition [RNA-Seq] 3.3
Identification of IL-27 as potent regulator of inflammatory osteolysis associated with vitamin E-blended ultra-high molecular weight polyethylene debris of orthopedic implants 3.26
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 3.24
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 3.23
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 3.22
RNAseq analysis of ESRP regulated splicing events in prostate cancer 3.21
Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs) 3.19
LNCaP treated with iBET 3.14
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 3.14
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 3.14
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 3.11
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 3.06
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 3.04
Transcriptional profiles of normal human mature B cells 3.04
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 3.03
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 3.03
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 3.03
Polarized B -cell functions 3.02
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 2.99
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 2.95
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 2.91
Gene expression signatures of innate lymphoid cells from human blood 2.91
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 2.91
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 2.88
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 2.88
Proliferation-correlated expression 2.86
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 2.85
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 2.81
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 2.8
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 2.8
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 2.79
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 2.79
Oncogenic MYC induces a dependency on the spliceosome in human cancer 2.78
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 2.77
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 2.77
Transcriptome-wide identification of CELF2 functional targets in T cells 2.77
Comparative Analysis of the Transcriptome of Latent Autoimmune Diabetes (LADA) Patients from Eastern China 2.75
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 2.74
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 2.73
Seletive inhibition of CDK9 in DLBCL cell lines 2.72
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 2.71
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 2.71
Tumor exosome integrins determine organotropic metastasis 2.69
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 2.68
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 2.68
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 2.67
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 2.67
Transcriptional profiling of CD45RO+CD57+CD4+ T cells 2.66
Human cells contain natural double-stranded RNAs with potential regulatory capacity 2.63
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 2.63
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 2.62
Differentially expressed genes post knock down of lincDUSP26 2.61
Hypoxic transcriptome of SQ20B human head and neck cancer cells 2.61
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 2.59
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 2.57
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 2.57
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 2.56
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 2.56
MYC dependent mRNA translation shapes gene expression and cell biology 2.55
Human lymph nodes maintain a unique subset of resident memory T cells with high functional potential important for protective immunity and immunotherapies 2.54
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.53
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 2.5
Characterization of human ILC2 subsets 2.49
JAK dependent survival of ALK- ALCL 2.49
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 2.48
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 2.48
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 2.46
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 2.45
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 2.42
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 2.42
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 2.4
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 2.4
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 2.39
HNRNPL and its RNA Targets in Prostate Cancer 2.38
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 2.38
Transcriptome analysis of peripheral blood monocytes 2.38
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 2.38
Global response to chemotherapy-induced apoptosis 2.36
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 2.35
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 2.35
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 2.35
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 2.35
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 2.34
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 2.34
mRNA expression profile of Lymphocytes 2.32
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 2.32
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 2.3
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 2.3
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 2.3
RNA-Seq of CD4+ T cells treated with AS1842856 or DMSO 2.29
Gene expression profiling in metabolically heterogeneous human lung tumors 2.28
Analysis of transcriptional regulation by Myt1 and Myt1l 2.28
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 2.27
Unique features and clinical importance of acute alloreactive immune responses 2.27
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 2.26
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 2.25
Effect of PBK knockdown on C4-2 cell transcriptome 2.23
quanTIseq: quantifying immune contexture of human tumors 2.22
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 2.21
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 2.21
BAF controls genome accessibility 2.2
RNAseq Study in CC-671 Treated Cal-51 Cells 2.2
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 2.18
Statins modulate endothelial transcriptional profile by inhibiting EZH2 2.18
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 2.17
Transcriptomic profiling of human peripheral blood-derived mast cells 2.16
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 2.16
Genetic-to-epigenetic Therapy for Pancreatic Cancer 2.16
Paxillin regulates genomic networks in prostate cancer [LNCaP] 2.14
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 2.13
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 2.12
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 2.12
Landscape and variation of RNA secondary structure across the human transcriptome 2.1
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 2.09
Microglia innatly develop within cerebral organoids 2.07
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 2.04
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 2.03
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 2.02
MYCL and EP400 are required for Max and MCPyV mediated gene activation 2.02
mRNA expression levels in splenic human mononuclear cells of mock- and HIV-1-infected humanized mice 2.0
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 1.98
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 1.98
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 1.97
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 1.96
Transcriptomes in healthy and CHB fetal hearts 1.95
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 1.95
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 1.94
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 1.93
MeRIP-seq for heat shock in B-cell lymphoma cells 1.9
Primary Human B-cell Temporal Response to CD40L Stimulation 1.9
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 1.89
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 1.87
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 1.87
Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation 1.86
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 1.85
Pharmacologic inhibition of STAT5 in AML 1.83
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 1.83
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 1.82
Defective structural RNA processing in relapsing-remitting multiple sclerosis 1.81
RNA-seq of resting and activated CD4+ T cells +-JQ1 1.78
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 1.77
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 1.77
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 1.77
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 1.76
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 1.74
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 1.74
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 1.72
Human Treg NaCl stimulation 1.71
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 1.71
Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection 1.71
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 1.68
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 1.66
RNA-seq of Single-Cell Genotyping of Transcriptomes 1.66
Single-Cell Genotyping of Transcriptomes 1.66
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 1.62
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 1.62
Global transcriptome analysis of HAP1 cells 1.62
Hijacking of stress response machinery by oncogenes in acute leukaemia 1.62
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 1.62
RNA-seq analysis of activated plasmacytoid dendritic cell subsets after viral infection 1.61
Transcriptional profiling of microglia; current state of the art and future perspectives 1.61
Widespread intronic polyadenylation diversifies immune cell transcriptomes 1.58
TAF1 is critical for AE driven leukemogenesis 1.58
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 1.58
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 1.57
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 1.56
LIN28A Over-expression RNAseq 1.56
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 1.55
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 1.55
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 1.54
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 1.53
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 1.51
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 1.51
Bone marrow derived human B cells [normal proB] 1.47
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 1.46
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 1.45
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 1.44
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 1.44
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 1.43
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 1.42
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 1.42
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 1.41
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 1.39
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 1.38
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 1.38
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 1.35
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 1.35
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 1.34
Hepatosplenic T cell lymphoma 1.34
Integrative Genomic and Transcriptomic Analysis Identified Candidate Genes Implicated in the Pathogenesis of Hepatosplenic T-cell Lymphoma 1.34
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 1.32
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 1.29
Human Treg IL-12 stimulation 1.28
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 1.28
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 1.27
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 1.26
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 1.26
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 1.26
Gene expression profile of multiple myeloma cell lines treated with CB-5083 1.25
Total RNA-Seq data from leukemic patients with complex structural variants 1.23
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 1.23
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 1.2
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 1.19
Transcription control by the ENL YEATS domain in acute leukemia 1.19
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 1.19
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 1.18
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 1.18
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 1.18
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 1.18
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 1.17
Transcriptome of diurnal human blood neutrophils 1.16
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 1.16
Analyses of T-ALL (COG study) 1.16
RNA sequencing of T-ALL (COG study) 1.16
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 1.14
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 1.14
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 1.13
Trascriptome of thyroid cancer-induced macrophages 1.12
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 1.08
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 1.07
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 1.06
Loss of CREBBP results in gene expression repression in lymphoma cells 1.06
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 1.06
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 1.04
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 1.04
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 1.04
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 1.03
Leucegene: ALL sequencing 1.01
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 1.01
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 1.01
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 1.01
STX4 Over-Expression in Human islets 1.01
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.0
RNA-seq of CD33 KO and control HSPCs 0.99
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 0.95
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 0.95
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 0.94
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 0.94
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia [RNA-seq] 0.93
Aging-associated patterns in the expression of human endogenous retroviruses 0.92
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 0.89
Effect of PRDM11 depletion in U2932 cells 0.89
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 0.89
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 0.88
Transcriptome of activated human and mouse MAIT cells 0.87
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 0.87
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 0.86
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 0.85
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 0.85
RNA sequencing data of whole blood cells of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women 0.85
RNA-Seq in neutrophils from Antiphospholipid Syndrome 0.84
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 0.82
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.82
RNAseq of T-ALL upon long non coding rna purturbation 0.81
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 0.81
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 0.8
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 0.8
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 0.8
RNA expression analysis upon JMJD1C depletion 0.77
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 0.77
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 0.77
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 0.77
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 0.77
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 0.76
Functional significance of the HIV-1 Tat signature amino acid residues 0.76
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 0.75
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 0.74
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia (RNA-Seq) 0.73
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia 0.73
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 0.73
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 0.73
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 0.72
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 0.72
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 0.71
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 0.71
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 0.7
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.7
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 0.69
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 [stranded] 0.69
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 0.69
Gene expression changes due to PARP knockdown in human cells 0.69
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.68
Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq] 0.68
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 0.68
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 0.68
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 0.66
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 0.66
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 0.66
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 0.65
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 0.65
Primate transcript and protein expression levels evolve under compensatory selection pressures 0.65
The DNA methylation landscape of human melanoma 0.64
The DNA methylation landscape of human melanoma [RNA-Seq] 0.64
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 0.63
RNA-Seq analysis of human neutrophils isolated by different protocols (Polymorphprep and negative selection) and incubated with and without in vitro cytokine stimulation 0.62
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 0.61
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 0.61
Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants 0.59
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 0.59
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.59
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 0.59
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 0.58
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.58
Oncogenic roles of ARID5B in T-ALL 0.58
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.58
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 0.57
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 0.57
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 0.56
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 0.56
HNRNPM-regulated splicing dependencies in prostate cancer 0.55
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 0.55
Discovering human diabetes-risk gene function with genetics and physiological assays 0.54
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 0.53
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 0.53
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 0.5
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 0.49
RNA-Seq from human ILC transitional populations 0.49
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis 0.49
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 0.47
Next generation sequencing of small RNAs isolated from exosomes in human semen 0.47
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 0.47
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 0.46
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 0.45
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 0.45
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.45
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.45
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 0.45
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 0.45
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.45
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 0.44
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 0.43
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 0.43
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.41
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.38
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.38
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 0.38
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 0.37
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 0.37
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 0.37
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 0.37
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 0.36
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 0.35
Stem and effector CD8 T-cells from human cancers 0.33
Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia 0.33
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 0.32
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 0.31
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 0.31
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 0.31
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.3
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.3
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 0.29
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 0.29
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.29
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 0.29
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 0.29
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 0.29
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 0.28
Neutrophils RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 0.27
Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products 0.27
Leucegene: AML sequencing (part 6) 0.27
Antiviral and anti-inflammatory properties of novel anti-HIV candidate ABX464 promotes specifics RNA splicing while preserving cellular RNA integrity. 0.26
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 0.25
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 0.25
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 0.25
Transcriptomic analysis of human macrophages in 3D 0.25
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 0.21
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.2
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.2
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.2
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.2
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.2
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 0.19
Human T-cell lymphoblastic lymphoma samples and control thymuses 0.19
Transcriptome analysis of diverse cell types infected with human cytomegalovirus 0.19
Generation and persistence of human tissue-resident memory T cells in lung transplantation 0.17
Transcriptional changes in lymphoma cells induced by LSD1 depletion 0.17
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 0.17
Expression analysis of the TAF1 syndrome 0.16
RNA editing in nascent RNA affects pre-mRNA splicing 0.16
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.15
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 0.15
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.14
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 0.13
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus 0.12
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 0.11
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 0.11
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.11
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 0.09
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 0.09
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 0.08
RNA-seq of primary patient AML samples 0.08
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 0.06
naive T cell heterogeneity after neonatal thymectomy 0.06
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 0.06
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 0.05
Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection 0.05
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 0.04
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.02
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 0.02
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 0.02
NHLRC1 re-expression in cancer cells 0.01
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.0


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