Gene Query: JAG1

Dataset Description Geneva Score
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 199.68
Differential gene expression in Jagged1 treated human dental pulp cells. 178.01
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 135.42
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 135.42
Role of COP1 on MAP kinase transcriptional output in melanoma 128.93
Gene Expression Profiling of SPOP Knocked Down Cell 123.42
An RNA-centric dissection of host complexes controlling flavivirus infection [RNA-Seq] 96.68
An RNA-centric dissection of host complexes controlling flavivirus infection 96.68
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 86.22
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 86.22
Role of CD133 molecule in WNT response and renal repair 86.15
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 78.4
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 70.5
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 69.25
RNA-seq analysis of AML cells in response to ASLAN003 69.02
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 65.17
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 65.17
ARID1A and ARID1B loss in HCT116 cells 64.98
Pharmacologic inhibition of STAT5 in AML 64.47
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 63.26
Random mono-allelic expression in MECP2-mutated cells 62.23
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function 59.21
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 57.54
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 57.51
Differetially expressed genes after hTR overexpression in U2OS cells 53.04
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 52.2
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 52.2
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 51.2
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 51.16
Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine 50.0
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 48.61
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 48.61
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 48.56
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 48.25
Replicated transcriptome profiling of Normal and Cancerous Prostate Cells [RNA-Seq] 47.96
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 47.8
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations 47.31
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq] 47.31
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 46.97
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 46.81
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 46.6
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 46.6
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 46.5
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 46.5
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 45.02
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 44.6
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 44.6
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 44.48
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 44.23
Gene expression profiling of iPSC-derived cardiomyocytes with BAG3 mutations 43.68
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 43.6
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 43.6
Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli 43.2
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 43.09
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 43.03
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 42.98
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 40.92
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 40.89
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 40.89
PRDM1 inhibits proliferation of human colon cancer organoids 40.71
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 40.11
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 40.05
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 40.02
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 39.74
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 38.9
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 38.61
Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels 37.92
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 37.9
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 37.33
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 37.15
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 37.04
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 36.82
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 36.72
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 36.13
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 36.03
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 35.76
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 35.72
Transcriptome profiling of Normal and Cancerous Prostate Cells 35.7
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 35.54
Genome-wide transcriptional response to random aneuploidy in human cells 35.1
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 35.06
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 35.03
High level DNA repair gene expression in human ES cells 34.4
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 34.38
Disruption of the exocyst induces podocyte loss and dysfunction 34.05
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 33.9
TCF7L1 knockdown in pancreatic cancer 33.87
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 33.86
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 33.86
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 33.82
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 33.54
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 33.22
Single-nucleotide-resolution mapping of HBV promoters using CAGE 33.21
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 32.74
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 32.47
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 32.47
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 32.47
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 32.29
A prostate cancer chromatin interaction map 32.2
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 32.05
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 31.84
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 31.63
Human HAP1 cells before and after nutrient deprivation 31.63
Modeling Familial Cancer with iPSC Approaches 31.44
Identification and Initial Functional Characterization of SENCR, a Long Non-Coding RNA Enriched in Human Vascular Cells 31.18
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 31.01
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 30.89
Regionally specified human pluripotent stem cell-derived astrocytes 30.79
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 30.47
Maturation of human iNSCs 30.45
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 30.45
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 30.44
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 30.37
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 30.36
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 30.36
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 30.09
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 30.01
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 30.01
PGE2 mediated gene expression changes in human cervical stromal cells 29.99
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 29.94
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 29.82
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 29.49
Gene expressions of H9s in different culture systems 29.47
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 29.43
RNA-seq analysis of RALD iPSCs after in vitro differentiation 29.4
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 28.96
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 28.86
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 28.66
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 28.66
MYCi975 regulates MYC target genes 28.61
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 28.46
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 28.23
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 28.19
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 27.8
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 27.77
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 27.74
Transcriptome profiling of hnRNP A2/B1 and A1 depleted cells 27.67
STRIPAK directs PP2A activity to promote oncogenic transformation 27.58
FBXW7 modulates stress response by post-translational modification of HSF1 27.48
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 27.48
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 27.44
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 27.4
METTL3 promotes translation in human cancer cells 27.32
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 27.11
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 27.08
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 27.08
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 27.04
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 27.04
High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872 27.02
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 26.97
Global gene expression differences between blood- and lymphatic-specific endothelial colony forming cells 26.93
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 26.93
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 26.85
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 26.54
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 26.54
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 26.51
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 26.23
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 26.23
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 26.23
Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle by inducing capillary sprouting and decreasing vascular permeability via reduced eNOS activity 26.16
Crizotinib v. DMSO in SW480 cells 26.13
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 26.1
UBC9 knockdown in bladder cancer T24 cell lines 26.07
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 25.95
Gene expression changes associated with resistance to tagraxofusp (SL-401) 25.93
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 25.92
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 25.9
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 25.9
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 25.77
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 25.32
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 25.31
Transcriptomic and gene ontology profiling of the human corneal cell types 25.3
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 25.22
Gene expression changes caused by KRAS in MCF-10A 25.15
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 25.07
WRN knockout effects upon gene expression in SW48 and OVK18 24.78
Transcriptomic analysis of human coronary artery endothelial cells stimulated with TNF-alpha in the presence and absence of ACSL3 siRNA 24.57
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 24.53
Transcriptome profiling of 5 human adenocarcinoma cell lines 24.35
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 24.15
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 24.09
RNA-seq of human aneuploid cell lines with Trisomy 21 23.95
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 23.93
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 23.64
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 23.57
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 23.56
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 23.52
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 23.52
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 23.52
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 23.43
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 23.25
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 23.24
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 23.2
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [RNA-Seq] 23.03
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression 23.03
RNA seq_PDX2_SHP099 22.97
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 22.93
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 22.88
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 22.83
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 22.46
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 22.45
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression [RNA-seq] 22.38
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression 22.38
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 22.36
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 22.31
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 22.21
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 22.06
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 21.95
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 21.93
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 21.87
Primary human trophoblast from term placenta 21.75
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes 21.74
Histone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq] 21.74
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 21.72
Global analyses of the effect of different cellular contexts on microRNA targeting 21.72
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 21.67
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 21.56
Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer 21.43
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 21.42
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 21.18
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 21.12
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 21.04
An siRNA screen identifies CHD4 as a target for epigenetic therapy 21.04
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 21.03
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 20.96
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 20.91
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 20.85
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 20.83
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 20.82
Targeting MTHFD2 in Acute Myeloid Leukemia 20.82
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 20.75
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 20.67
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 20.64
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 20.64
Evolving Spindlin1 Small Molecule Inhibitors Using Protein Microarrays 20.61
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 20.59
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 20.5
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 20.5
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 20.3
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 20.29
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 20.28
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 20.28
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 20.27
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 20.22
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 20.09
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 20.08
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 19.89
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 19.89
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 19.86
RNA-Seq analysis of breast cancer cells after shikonin treatment 19.7
Discovering the anti-cancer potential of non-oncology drugs by systematic PRISM profiling 19.62
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 19.59
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 19.56
Transcriptome analysis of U87 cells upon LINC00152 knockdown 19.51
Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons 19.47
Irf9 function in immunity in mouse 19.47
Region-specific Innate Antiviral Responses of the Human Epididymis 19.43
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 19.38
Generation of trichogenic adipose-derived stem cells by expression of three factors 19.25
Atheroprotective flow alters EZH2/H3K27me3 dependent transcriptional profile in human endothelial cells 19.14
Statins modulate endothelial transcriptional profile by inhibiting EZH2 19.12
MARS Seq data from human cortical organoids 19.11
RNA-seq analysis and shRNA screen of breast cancer 19.04
RNA-seq analysis of breast cancer 19.04
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 19.0
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 18.93
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 18.88
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 18.81
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 18.66
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 18.57
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 18.52
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 18.23
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 18.22
Paxillin regulates genomic networks in prostate cancer [C4-2] 18.21
Ribosomal footprinting of MDA-Parental and MDA-LM2 18.21
Aortic Valve Tissue: Stenosis vs. Sclerosis 18.18
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 18.12
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 18.07
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 18.07
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 18.03
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 18.03
Organoids derived from directly reprogrammed human hepatocytes for modeling liver cancer initiation 17.98
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 17.97
Selective suppression of endothelial cytokine production by progesterone receptor 17.96
Selective suppression of endothelial cytokine production by progesterone receptor [RNA-seq] 17.96
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 17.96
Bulk RNA-sequencing of cell types isolated by FACS from normal human prostates 17.95
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 17.89
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 17.87
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 17.82
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 17.81
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 17.8
Illumina Total RNA-seq in HeLa 17.56
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 17.54
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 17.52
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 17.43
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 17.43
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 17.42
Ribosomal footprinting of CN34-Parental and CN34-LM1a 17.39
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 17.34
Knockdown of ADNP in HCT116 colon cancer cells 17.23
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 17.16
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 17.03
Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells 16.99
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 16.9
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 16.86
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 16.77
RNA-seq in LNCaP cell line overexpressing WT or mutant FOXA1 16.75
Forkhead domain mutations in FOXA1 drive prostate cancer cell progression 16.75
High-throughput sequencing of the human hepatic progenitor cell niche in PSC and HCV. 16.72
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 16.62
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 16.56
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 16.41
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 16.41
Selective expression of long non-coding RNAs in a breast cancer cell progression model 16.4
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 16.3
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 16.3
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 16.23
circRNA profile in hypopharyngeal cancer 16.2
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 16.13
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 16.13
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 16.13
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 16.1
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 16.06
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 15.76
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 15.76
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 15.61
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 15.54
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 15.16
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 15.05
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 14.86
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 14.81
Human embryonic stem cells in E8 and AKIT culture medium 14.81
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 14.77
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 14.69
Characterization of human ILC2 subsets 14.57
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 14.52
Differential gene expressions in the heart of hypertrophic cardiomyopathy patients 14.5
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 14.5
Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice 14.06
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 13.91
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 13.91
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 13.83
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 13.79
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 13.62
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 13.59
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 13.54
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 13.53
CSL RNA-Seq on HKC and SCC cell lines 13.44
CSL 13.44
Interleukin-1β induces mitochondrial DAMP production to activate STING-dependent innate immune programs 13.4
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 13.4
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 13.37
Gene expression profile in breast cancer cell lines using RNA sequencing 13.35
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 13.28
NHLRC1 re-expression in cancer cells 13.23
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 13.13
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 13.09
Differential gene expression of human melanoma cells [RNA-seq] 13.09
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 13.0
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 13.0
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 13.0
DAOY-Notch1/Notch2 knockout: transcriptome comparison 12.96
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 12.88
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 12.72
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 12.62
Tpl-2 and MEK small molecule inhibitors 12.6
Tpl-2 small molecule project 12.6
Capturing the Interactome of Newly Transcribed RNA (RICK) 11.94
Capturing the Interactome of Newly Transcribed RNA 11.94
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 11.94
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 11.71
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 11.64
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 11.32
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 11.25
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 11.22
Genome-wide chromatin analysis of Ewing sarcoma 11.22
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 11.22
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 11.22
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 11.21
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 11.18
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 11.17
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 11.17
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 10.74
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 10.58
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 10.32
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 10.32
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 10.24
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 10.19
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 10.16
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 10.02
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 9.76
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 9.76
MARCKS and lnc-MARCKS act as inflammation regulators 9.58
Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells 9.4
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 9.37
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 9.37
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 9.26
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 9.24
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 9.23
The chromatin modifier CHD8 targets autism risk genes during human neurodevelopment  8.96
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 8.91
Zika virus infection reprograms global transcription of host cells to allow sustained infection 8.86
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 8.86
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 8.86
Characterizing the Chemoresistant Ovarian Cancer Population using the Heterogeneous PDX 8.73
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 8.56
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 8.56
T47D xenografts treated with various combinations of ER- and PR-targeting therapies 8.56
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 8.16
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 8.1
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 8.1
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 7.99
Iron response of HepG2 cells 7.91
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 7.89
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 7.61
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 7.61
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 7.57
The comparison of high-throughput single-cell RNA-seq methods 7.5
MicroRNA Marker Based Prognostication of Oral Squamous Cell Carcinoma 7.42
RNA deep sequencing analysis of glioma stem cells(GSCs) and non-GSCs 7.33
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 7.02
Single-cell ID-seq identifies BMP signaling as a driver of a late stage epidermal differentiation program. 7.01
Effect of BMP inhibition or stimulation of primary human keratinocytes 7.01
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 6.86
Differential responses of human fetal brain neural stem cells to Zika virus infection 6.81
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines 6.79
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines [RNA-seq] 6.79
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 6.77
Ets homologous factor has critical roles in epithelial dysfunction in airway disease [RNA-seq] 6.73
Ets homologous factor has critical roles in epithelial dysfunction in airway disease 6.73
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 6.3
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 6.28
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 6.02
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 6.01
KSDM1b Role in Ewing Sarcoma 5.86
mRNA-Seq profiling SIX2+ and Foxd1+ cells in mouse embryonic and SIX2+ and SIX2-/MEIS1+ cells human fetal kidney 5.84
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 5.82
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels 5.82
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq] 5.82
Human interleukin-4 treated regulatory macrophages promote epithelial wound healing and reduce colitis in an mouse model 5.77
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 5.64
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 5.11
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 5.11
BET bromodomain inhibition 4.98
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 4.98
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 4.89
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 4.88
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 4.57
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 4.45
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 4.33
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 4.32
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 4.3
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 4.29
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 3.8
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 3.69
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 3.66
Copper Regulation of HIF-1 Transcription Activity 3.66
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [RNA-seq] 3.54
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes 3.54
TGF-β regulation of miRNA expression in pancreatic cancer 3.31
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines 3.27
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 3.25
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 3.21
Vammin induces a highly efficient angiogenic response through VEGFR-2/NRP-1 and bypasses the regulatory function of VEGFR-1 3.19
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 3.04
MCF-7 as a model for functional analysis of breast cancer risk variants 2.98
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 2.89
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 2.89
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 2.72
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 2.49
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 2.22
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 1.97
Entrectinib Resistance in a Neuroblastoma Xenograft Model 1.95
Gene expression profile of human placenta from T. Cruzi infected mothers 1.91
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.88
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 1.84
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 1.83
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 1.67
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 1.67
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 1.58
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 1.48
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 1.47
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 1.28
BMS-470539 on human synovial fibroblasts 1.16
RNA sequencing analysis of selumetinib-resistant CRC cells lines 1.16
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 1.13
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 1.1
iPSC derived motor neuron cultures from C9ORF72 carriers 1.06
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 0.93
MRTF activates TEAD-YAP target gene expression 0.83
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 0.77
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 0.75
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation 0.4
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 0.38
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 0.38
Finding missing proteins from epigenetically manipulated human cells 0.1
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.07
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells 0.07
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 0.07


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