Gene Query: JAK3

Dataset Description Geneva Score
Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection 66.36
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 44.4
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 34.68
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 30.75
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 29.91
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 29.72
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 29.72
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 27.59
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 27.32
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 27.04
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 25.54
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 25.54
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 24.37
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 23.55
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 23.15
Transcriptome of Stabilin-1 siRNA transfected human monocytes 22.95
Platelet Transcriptome Profiling in HIV and ABCC4 as a Biomarker of Platelet Activity 22.39
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 21.45
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (mRNA-Seq) 21.01
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 20.99
Characterization of Human Pegivirus Infection in Liver Transplantation Recipients 20.63
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 20.49
Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 19.04
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 18.2
A Unique Epigenomic Landscape Defines Human Erythropoiesis 18.2
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 18.13
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 18.13
CD74 role in transcription regulation [RNA-seq] 18.02
CD74 role in transcription regulation 18.02
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 17.16
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 16.73
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 16.21
A practical evaluation of alignment algorithms for RNA variant calling analysis 16.18
Global analysis of alternative splicing regulated by RBM10 16.18
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 16.0
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 15.54
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 15.54
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 15.29
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 15.08
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 15.08
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 14.97
RNA-seq analysis of BAP1-depleted uveal melanoma cells 14.5
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing 14.25
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing [RNA-seq] 14.25
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 14.23
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 14.23
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 14.17
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 14.17
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 14.14
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 14.02
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 14.02
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 13.96
Antibody-Mediated Inhibition of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity 13.8
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 13.75
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 13.67
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 13.64
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 13.44
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 13.13
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 13.13
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 12.78
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 12.65
Total RNA-seq in ALL-SIL upon TLX1 knockdown 12.49
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [RNA-Seq] 12.35
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray 12.35
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 12.26
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 12.24
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 12.24
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells [RNA-Seq] 12.01
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells 12.01
Intron retention induced by microsatellite expansions as a disease biomarker. 11.91
RNA-seq analysis of uveal melanoma cells treated with FR900359 11.6
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 11.51
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene (RNAseq) 11.32
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene 11.32
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 11.14
MeRIP-seq for heat shock in B-cell lymphoma cells 11.13
The role of FAM46C in myeloma cells [sequencing] 11.03
The role of FAM46C in myeloma cells 11.03
Integrating single-cell transcriptomic data across different conditions, technologies, and species 11.02
Transcriptome analysis revealed impaired cAMP responsiveness in PHF21A-deficient human cells 10.85
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 10.82
Transcriptional changes during naturally-acquired ZIKA Virus infection render dendritic cells highly conducive to viral replication 10.43
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 10.41
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 10.34
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 10.28
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 10.24
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 10.09
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 10.0
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 10.0
Generation and functional characterization of MDSC-like cells 9.87
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 9.82
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 9.8
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 9.8
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 9.77
RNA-sequencing of formalin fixed human primary melanoma tissue 9.71
A novel target of EZH1/2 for treatment of mantle cell lymphoma 9.69
SRSF2 mutations impair hematopoiesis and alter exon recognition 9.55
circRNA profile in hypopharyngeal cancer 9.53
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 9.53
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 9.49
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 9.49
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 9.44
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 9.27
Intrahepatic MAIT cell gene expression revealed by RNA-seq 9.22
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 9.18
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 9.12
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 9.07
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway 8.97
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 8.97
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 8.89
Diarrhoeal mechanisms of the Campylobacter jejuni enteritis 8.84
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 8.83
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 8.8
RNA sequencing of hPSC-derived cardiac progenitors and endocardium 8.76
Macrophage Ad5f35 PhenoMap 8.63
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 8.48
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 8.48
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 8.46
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 8.46
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 8.44
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 8.43
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 8.43
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 8.41
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 8.32
Antiviral and anti-inflammatory properties of novel anti-HIV candidate ABX464 promotes specifics RNA splicing while preserving cellular RNA integrity. 8.06
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 7.96
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 7.94
CD1c+ dendritic cell activation by Plasmodium falciparum-infected red blood cells 7.74
Transcriptome sequencing of differentially expressed genes in mouse and human skin with and without NCSTN mutation 7.71
Transcriptome sequencing of differentially expressed genes in acne inversa (AI) patients with NCSTN mutation and healthy individuals 7.71
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 7.68
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 7.68
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition [RNA-Seq] 7.68
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition 7.68
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq] 7.58
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 7.5
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 7.5
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 7.49
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 7.29
Regulation of Lipids is Central to Replicative Senescence 7.28
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 7.17
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 6.89
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 6.82
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 6.78
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 6.77
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 6.74
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 6.69
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 6.63
Transcriptome of diurnal human blood neutrophils 6.58
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 6.56
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 6.5
Landscape and variation of RNA secondary structure across the human transcriptome 6.46
CD86 regulates a pro-survival signal in myeloma cells 6.41
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 6.38
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 6.38
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 6.3
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 6.29
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 6.29
A role for ZNF598 in post-transcriptional gene regulation 6.27
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 6.26
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 6.24
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 6.19
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 6.19
Targeted enhancer activation by a subunit of the integrator complex 6.16
Single cell transcriptome of peritoneal cells 6.16
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 6.11
RNA-seq of stable and unstable section of human atherosclerotic plaques 6.07
Stem and effector CD8 T-cells from human cancers 6.07
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 6.01
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 5.98
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 5.97
CROP-Seq in Primary Human T Cells 5.94
CHD1 regulates cell fate determination by activation of differentiation-induced genes 5.83
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 5.78
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 5.78
Transcriptome of activated human and mouse MAIT cells 5.71
Short and Long RNA sequencing of human mature erythrocytes 5.56
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 5.51
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 5.38
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 5.38
Improved LCL to iPSC reprogramming: RNA Analysis of LCLs, reprogrammed iPSCs, and differentiated NSCs reveal potential regulatory and functional processes involved in these cellular transitions. 5.36
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression 5.35
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 5.32
Microglia innatly develop within cerebral organoids 5.3
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 5.2
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 5.13
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 5.05
Selective suppression of endothelial cytokine production by progesterone receptor 5.05
Selective suppression of endothelial cytokine production by progesterone receptor [RNA-seq] 5.05
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 5.05
Effects of rFVIIIFc on human macrophages 5.01
Identification of a core p53 transcriptional program with highly fractionated tumor suppressive activity 4.93
GRO-seq from HCT116, MCF7 and SJSA cell lines treated with DMSO and Nutlin 4.93
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 4.85
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 4.85
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 4.79
Gene expression profile of multiple myeloma cell lines treated with CB-5083 4.78
Transcriptional profiles of normal human mature B cells 4.68
Clinker: visualizing fusion genes detected in RNA-seq data 4.67
Molecular Biomarkers Screened by Next-generation RNA Sequencing for non-sentinel lymph node status predicting in breast cancer patients with metastatic sentinel lymph node 4.66
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 4.62
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 4.6
RNA sequencing with KSHV infection and enrichment for circular RNAs 4.57
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 4.55
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 4.47
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 4.42
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with pancreatic carcinoma 4.41
SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample 4.4
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 4.38
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 4.37
Dynamic 3D chromosomal landscapes in acute leukemia 4.37
Gene expression signatures of innate lymphoid cells from human blood 4.37
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 4.35
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 4.34
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 4.34
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 4.33
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 4.32
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 4.31
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 4.29
Identification of differentially expressed circRNA in gallbladder cancer compared with matched normal tissue 4.29
Bone marrow derived human B cells [normal proB] 4.27
Proteolytic cleavage by taspase1 and the regulation of the stability of MLL1 4.27
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways 4.27
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 4.24
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 4.23
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 4.23
ML29755 RNA-seq data 4.19
RNA-Seq study of Cell lines rendered resistant to idelalisib and ibrutinib 4.19
MYCi975 regulates MYC target genes 4.19
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 4.16
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NfkB-dependent differentiation of AML cells 4.12
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 4.1
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 4.09
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 4.01
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 3.97
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 3.97
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 3.94
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 3.93
Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation 3.93
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 3.87
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 3.85
Identification and validation of differentially expressed transcripts by RNA-Sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis 3.83
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 3.83
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 3.79
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 3.75
Long noncoding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells 3.73
RNA-seq of Human neck of femur (NOF) fracture hip and osteoarthritic (OA) cartilage 3.73
Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs 3.71
RNA Sequencing Analysis of villus tissues from unexplained recurrent spontaneous abortion patients and controls with induced abortions 3.7
Non-inflammatory tumor microenvironment of Diffuse Intrinsic Pontine Glioma (DIPG) 3.69
Improving fibroblast characterization using single-cell RNA sequencing: an optimized tissue disaggregation and data processing pipeline 3.68
FOXP3 protects conventional human T cells from premature restimulation-induced cell death 3.63
Multiple sclerosis and EAE 3.63
Human optic chiasm from healthy controls and multiple sclerosis patients 3.63
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 3.62
Transcriptional profile in human S. haematobium infection 3.62
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 3.61
Common inflammatory pathways between NEC and Crohn's disease 3.57
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 3.57
RNA sequencing of heart samples of myotonic dystrophic (DM1) patients 3.57
MEIS1 regulates hematopoiesis in hPSCs 3.53
NAPRT activation of macrophages 3.48
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 3.47
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 3.44
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 3.44
Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq] 3.44
Widespread intronic polyadenylation diversifies immune cell transcriptomes 3.42
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 3.41
Total RNA-seq in ALL-SIL upon JQ1 inhibition 3.41
RNA-seq of CD33 KO and control HSPCs 3.4
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 3.36
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 3.35
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 3.35
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 3.35
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 3.34
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 3.34
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 3.32
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 3.32
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 3.32
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 3.3
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 3.23
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 3.2
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 3.2
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 3.2
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 3.19
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 3.19
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 3.18
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 3.14
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 3.14
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 3.14
Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs) 3.13
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 3.05
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 3.01
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells 3.01
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] 3.01
Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor 2.97
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 2.95
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 2.93
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 2.87
An acquired vulnerability of drug resistant melanoma with therapeutic potential 2.86
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 2.86
Transcriptomes change differerntly in differernt cancer cells upon EPZ-6438 treatment 2.86
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 2.84
Transcriptomic analysis of human tonsillar TFH subsets 2.77
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 2.76
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 2.74
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 2.73
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 2.7
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 2.7
mRNA expression profile of Lymphocytes 2.63
RNA-seq melanoma 2.62
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 2.6
RNA-seq in endometrial stromal tumors 2.59
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 2.55
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 2.55
The cytokine environment influence on human skin-derived T cells 2.55
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 2.54
Genome-wide identification of cancer-specific alternative splicing in circRNA 2.52
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 2.51
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 2.51
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 2.48
Transcriptome Profiling of Human Primary Monocytes 2.47
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 2.4
Transcriptomic responses to Ivacaftor and prediction of Ivacaftor clinical responsiveness 2.4
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 2.4
Human Tfh cell RNA bulk sequencing 2.27
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 2.26
Leucegene: AML sequencing (part 6) 2.26
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 2.26
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 2.21
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [Primary RNA-Seq] 2.21
Human lymph nodes maintain a unique subset of resident memory T cells with high functional potential important for protective immunity and immunotherapies 2.17
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 2.15
A map of gene expression in neutrophil-like cell lines 2.15
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 2.15
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 2.14
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 2.11
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 2.11
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 2.09
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 2.02
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 2.0
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 1.98
Human T-cell lymphoblastic lymphoma samples and control thymuses 1.98
quanTIseq: quantifying immune contexture of human tumors 1.97
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 1.94
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 1.94
Human neutrophil genome during PMA- and E. coli encounter-induced activation 1.94
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 1.92
Tissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases 1.91
RNA-Seq and expression data from human adipose tissue 1.91
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 1.9
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 1.87
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 1.86
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 1.84
RNA-seq of primary patient AML samples 1.84
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 1.83
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 1.83
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 1.82
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 1.8
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 1.77
Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma 1.76
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 1.73
Gene expression activation in CLL mediated by MSCs contact 1.72
Characterization of human ILC2 subsets 1.71
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 1.62
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 1.61
Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis 1.6
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.6
RNA sequencing of T-ALL (COG study) 1.58
Analyses of T-ALL (COG study) 1.58
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 1.54
Diarrhea in lymphocytic colitis: ERK1/2-dependent ENaC dysregulation and claudin-4-, -5- and -8-related barrier defects 1.54
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 1.53
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 1.49
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 1.49
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 1.48
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 1.48
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 1.45
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with colorectal carcinoma 1.45
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 1.45
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.41
Reprogrammed myeloid cell transcriptomes in NSCLC 1.4
RNA-seq analysis of the human fetal kidney. 1.4
HEK293 Heat-shock experiment 1.38
The DNA methylation landscape of human melanoma [RNA-Seq] 1.38
The DNA methylation landscape of human melanoma 1.38
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 1.35
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 1.35
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 1.33
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 1.33
Long noncoding RNA LNMAT1 promotes lymphatic metastasis in bladder cancer 1.3
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_TK] 1.25
Oncogenic roles of ARID5B in T-ALL 1.24
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 1.24
Ro60-knockout cells 1.23
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 1.21
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 1.21
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 1.21
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (TLR perturbation Bulk RNA-Seq) 1.19
BCL11B 1.18
Global reduction in H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 1.17
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 1.17
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 1.16
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 1.16
Transcriptomes in healthy and CHB fetal hearts 1.15
RNA-Seq analysis of human neutrophils isolated by different protocols (Polymorphprep and negative selection) and incubated with and without in vitro cytokine stimulation 1.14
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 1.12
MAIT cell RNA sequencing 1.12
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 1.09
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis 1.09
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 1.08
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 1.03
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 1.0
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 0.97
TAF1 is critical for AE driven leukemogenesis 0.96
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 0.96
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 0.95
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) reprograms melanoma microenvironment to promote antitumor T cell responses 0.94
Gene expression profiling in metabolically heterogeneous human lung tumors 0.94
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 0.89
Identification of long noncoding RNAs in T-ALL cell lines 0.88
Transcriptomic profiling of human peripheral blood-derived mast cells 0.88
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 0.88
Gene expression profile difference among renal location in a stone former 0.87
Unique features and clinical importance of acute alloreactive immune responses 0.85
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 0.84
Total RNA-Seq data from leukemic patients with complex structural variants 0.83
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 0.82
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 0.81
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 0.8
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 0.8
The Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth 0.79
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 0.78
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 0.78
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.78
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 0.76
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 0.76
Potential signaling pathways and gene signatures associated with brain metastases in NSCLC patients 0.73
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 0.72
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 0.72
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 0.71
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 0.68
RNA-sequencing of human tendon after injury 0.67
Expression patterns in chronic thromboembolic pulmonary hypertension 0.66
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 0.65
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 0.64
Human Treg IL-12 stimulation 0.63
Transcriptome analysis of diverse cell types infected with human cytomegalovirus 0.63
Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease 0.61
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 0.61
MHC Transcriptomic landscape at haplotype-specific resolution 0.58
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 0.58
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 0.53
Molecular analysis of renal cell carcinoma with unclassfied histology 0.52
Molecular analysis of renal cell carcinoma with unclassfied histology [gene expression] 0.52
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 0.49
Generation and persistence of human tissue-resident memory T cells in lung transplantation 0.47
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction. 0.44
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction [RNA-seq] 0.44
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 0.44
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 0.43
Specific molecular signatures underlie response to decitabine in CMML 0.42
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.42
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 0.36
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.34
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 0.32
Pluripotent stem cell models of Blau syndrome reveal an IFN-<gamma>-dependent inflammatory response in macrophages 0.31
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 0.29
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 0.29
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 0.26
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 0.25
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors 0.23
circNFIB suppresses lymphatic metastasis of pancreatic cancer 0.23
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 0.22
The expression profiles of GBC liver metastasis 0.19
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 0.17
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 0.17
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 0.15
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 0.14
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.14
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in Chronic Lymphocytic Leukemia 0.13
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 0.11
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 0.11
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 0.09
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation 0.09
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 0.09
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 0.09
Widespread regulated alternative splicing of single codons accelerates proteome evolution 0.08
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 0.08
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 0.07
Transcriptomic analysis of human macrophages in 3D 0.05
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.04
The role of m6A/m-RNA methylation in stress response regulation 0.04
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.04
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 0.04
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 0.04
Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms 0.02
Integrative analysis of RNA, translation and protein levels reveals distinct regulatory variation across humans 0.02
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.01
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.01


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