Gene Query: KLHL15

Dataset Description Geneva Score
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 46.34
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4 41.7
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 39.56
Altering cancer transcriptomes using epigenomic inhibitors 39.56
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 38.48
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 38.46
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 35.9
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 33.24
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 33.24
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 32.29
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 30.1
Global gene expression profiling from LeuCAG3'tsRNA depleted- HeLa and HCT-116 cell lines through 50 base pair paired-end RNA-seq 29.12
Tracking of dCas9-methyltransferase footprints 28.45
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 27.9
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 26.12
Effect of BB608 on Gene Expression in HNSCC Cell Line 26.01
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 25.18
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 23.44
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 23.13
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 22.48
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 22.48
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 22.47
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 22.28
HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma associated herpesvirus ORF57 protein and host pre-mRNA metabolism 22.09
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 22.01
Uridylation by TUT4 and TUT7 marks mRNA for degradation 21.6
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 21.49
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 21.45
Profiling of escape kinetics of viruses subjected to RNAi 21.32
Transcriptomic analysis of LSD1 20.67
Differential Protein Occupancy Profiling of the mRNA Transcriptome 20.02
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 19.99
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 19.48
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 19.46
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 19.23
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 19.13
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 18.89
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 18.45
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 18.45
Global analysis of alternative splicing regulated by RBM10 17.72
Effect of Hotair overexpression in human breast cancer cell lines 17.45
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 16.91
R430: A potent inbibitor of DNA and RNA viruses 16.62
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 16.37
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 16.2
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 16.2
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 16.06
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 16.05
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 16.05
KSDM1b Role in Ewing Sarcoma 15.92
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 15.83
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 15.45
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 15.41
A Unique Epigenomic Landscape Defines Human Erythropoiesis 15.39
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 15.39
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 15.13
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 15.1
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 14.8
Tracking distinct RNA populations using efficient and reversible covalent chemistry 14.68
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 14.67
SUV420H2 knockdown in PANC-1 14.66
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 14.41
Uridylation by TUT4 and TUT7 marks mRNA for degradation [RNA-Seq] 14.35
The bromodomain protein BRD4 regulates splicing during heat shock 14.29
Recovery and analysis of nascent RNA 14.21
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 14.21
Human cell line and subcutaneous tumor 14.2
Human HAP1 cells before and after nutrient deprivation 13.92
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 13.92
Transcriptome analysis in Neobractatin treated cells 13.87
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 13.78
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 13.54
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 13.51
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 13.29
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 12.94
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 12.71
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 12.56
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 12.47
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 12.44
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 12.4
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 12.37
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 12.35
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 12.33
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 12.24
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 12.21
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 12.19
Determining mRNA half-lives on a transcriptome-wide scale 12.18
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 12.15
RNA-seq of YB5 cells treated with Proscillaridin A 12.05
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 11.94
MYCL and EP400 are required for Max and MCPyV mediated gene activation 11.91
PGE2 mediated gene expression changes in human cervical stromal cells 11.89
Lysine benzoylation is a novel histone mark [RNA-seq] 11.82
Lysine benzoylation is a novel histone mark 11.82
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 11.71
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 11.56
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 11.22
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 11.22
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 2h] 11.18
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 11.13
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 11.13
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 10.92
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 10.86
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 10.8
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 10.79
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 10.71
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 10.53
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 10.41
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 10.35
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 10.24
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 10.19
Systematic discovery of endogenous human ribonucleoprotein complexes 10.13
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 9.84
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 9.84
Impact of dieldrin on transcription in Jurkat T cells 9.77
Transcriptomes of human monocytes after ex vivo exposure to uric acid 9.63
Gene expression in PANC1 cells treated with Rakicidin 9.55
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 9.54
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 9.48
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 9.47
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 9.47
Transcriptional profiling of CD45RO+CD57+CD4+ T cells 9.31
RNAseq analysis of ESRP regulated splicing events in prostate cancer 9.27
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 9.17
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 9.15
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 9.15
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 9.13
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 9.13
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 9.04
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 9.03
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 9.02
Next generation sequencing on knockdown of AC093323.3 in lung cancer cells 8.95
UV_24h_GRO-Seq 8.91
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 8.82
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 8.82
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 8.81
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 8.81
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 8.81
RNA expression following TMPRSS11B overexpression or depletion 8.8
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 8.73
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 8.69
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 8.66
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 8.66
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 8.55
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 8.52
Gene expression profile of human iPSC-derived nephron progenitor cells 8.5
High-throughput sequencing of PROMPT-enriched samples. 8.49
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 8.43
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 8.37
CD95/Fas ligand mRNA is toxic to cells 8.35
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 8.29
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 8.23
Noncoding regions are the main source of targetable tumor-specific antigens 7.99
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 7.98
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 7.98
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 7.97
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 7.97
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 7.93
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 7.93
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 7.85
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 7.84
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 7.81
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 7.81
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 7.75
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 7.68
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 7.68
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 7.67
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 7.61
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 7.53
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 7.46
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 7.46
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 7.45
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 7.43
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 7.36
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 7.32
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 7.26
7.24
DRB/GRO-Seq -/+ UV 7.17
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 7.12
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 7.11
Inhibition of TNBC metastasis by Gpx1 7.11
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 7.09
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 7.06
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 7.05
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 7.05
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 7.0
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 7.0
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 6.96
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 6.92
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 6.92
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 6.92
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 6.86
The landscape of alternative splicing in aggressive prostate cancers 6.84
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 6.82
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 6.77
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 6.75
HEK293 TFAM Knockout Expression Study 6.67
NHLRC1 re-expression in cancer cells 6.67
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 6.67
Oncogenic roles of ARID5B in T-ALL 6.67
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 6.62
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 6.62
3’ Uridylation Expands miRNA Target Repertoire 6.53
Transcriptional profile in human S. haematobium infection 6.52
Functional role of SLIT2 and ROBO1 in trophoblasts 6.45
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 6.4
Genes significantly down or Up-regulated upon RNF219 knockdown 6.37
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 6.34
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 6.19
Human embryonic stem cells in E8 and AKIT culture medium 6.17
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 6.17
WRN knockout effects upon gene expression in SW48 and OVK18 6.14
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 6.13
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics. 6.1
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 6.08
Transcriptome-wide analysis of adipose circular RNAs reveals their dynamic regulation in obesity and functional role in adipogenesis 6.07
RNA-seq of cancer cell lines treated with T-025 6.04
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 5.98
Biological effect of chronic mistranslation in mammalian cells 5.9
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 5.9
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 5.83
Genetic-to-epigenetic Therapy for Pancreatic Cancer 5.79
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 5.78
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 5.78
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 5.78
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 5.76
CD73 knockdown effect in pancreatic cancer cell lines 5.74
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 5.73
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 5.72
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 5.72
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 5.72
IDH3a KO RNA-seq 5.72
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 5.71
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 5.58
Chromatin-informed inference of transcriptional programs in gynecologic cancers 5.58
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 5.53
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 5.5
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 5.49
Differential expression of genes in AD169-infected MRC5. 5.46
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 5.45
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 5.42
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 5.41
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 5.37
NKX2.2 5.37
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 5.24
Knockdown of ADNP in HCT116 colon cancer cells 5.24
LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines 5.22
Impact of HypERrlnc Knockdown on the human pericyte transcriptome 5.18
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 5.17
Gene expression profiling of leukemia cells following asparagine depletion 5.12
Effect of disulfiram treatment on pediatric high grade glioma 5.09
Total RNA-seq in ALL-SIL upon TLX1 knockdown 5.04
Genome-wide discovery of human splicing branchpoints [RNAse] 5.01
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 5.0
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 5.0
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 5.0
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 4.99
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 4.99
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 4.99
EWSR1 influences alternative splicing through direct and indirect mechanisms 4.99
Transcriptional responses of human insulinoma cells to acute cytokine exposure 4.98
N6-methyladenosine (m6A) profiling of EndoC-bH1 cell line and RNA seq of Mettl14 knockout mice beta cell 4.98
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 4.93
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 4.87
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 4.87
Comparing gene expression in iPSC derived RPE from control and AMD donors 4.84
Human ovarian granulosa cell transcriptome 4.82
Neonatal and adult human testis defined at the single-cell level 4.82
Role of XRN2 ribonucleolytic activity in RNA metabolism 4.79
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 4.76
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 4.75
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 4.73
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 4.72
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 4.71
U1 snRNP telescripting regulates size-function stratified human genome 4.71
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 4.7
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 4.69
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 4.67
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 4.67
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 4.67
Effect of PRDM11 depletion in U2932 cells 4.67
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 4.65
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 4.65
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 4.62
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 4.62
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 4.61
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 4.61
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 4.59
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 4.58
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 4.56
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 4.55
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 4.52
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 4.5
Hijacking of stress response machinery by oncogenes in acute leukaemia 4.5
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 4.47
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 4.47
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC 4.47
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC [Total RNA-Seq] 4.47
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 4.44
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 4.44
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 4.38
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing 4.32
Transcriptomic analysis of ERR alpha orphan nuclear receptor 4.31
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 4.3
A transcriptome dataset revealing the molecular features of breast cancer stem cells 4.27
Global transcriptome analysis of HAP1 cells 4.24
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 4.24
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 4.22
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 4.22
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 4.21
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 4.13
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 4.11
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 4.1
MAIT cell RNA sequencing 4.08
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 4.07
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 4.07
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 4.06
Transcriptional dependencies in diffuse intrinsic pontine glioma 4.0
Global Mapping of Human RNA-RNA Interactions 3.99
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 3.92
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 3.92
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 3.88
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 3.87
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 3.87
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 3.87
The conserved transcriptional landscapes in human spermatogenesis 3.84
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 3.83
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 3.82
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 3.77
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 3.76
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  3.75
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 3.74
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 3.73
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 3.64
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 3.62
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 3.6
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 3.6
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 3.58
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 3.54
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 3.51
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 3.47
RNA-Seq analysis of human neutrophils isolated by different protocols (Polymorphprep and negative selection) and incubated with and without in vitro cytokine stimulation 3.44
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 3.42
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 3.41
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 3.38
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 3.38
RNA-seq of MDA-MB-231 cells with TET1 knockout 3.34
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 3.34
Leucegene: ALL sequencing 3.32
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 3.31
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 3.28
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 3.26
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 3.26
Generation and persistence of human tissue-resident memory T cells in lung transplantation 3.25
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 3.24
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 3.22
miR941 overexpression experiment 3.19
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 3.16
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 3.12
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 3.07
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 3.04
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 3.01
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 3.01
Mitochondrial dsRNA triggers antiviral signalling in humans 3.01
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 3.0
Fibroblasts in cholesteatoma activate osteoclasts. 2.98
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 2.95
Dermal endothelial cells of type 2 diabetic patients 2.95
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 2.93
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 2.92
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 2.92
Polarized B -cell functions 2.89
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 2.89
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 2.89
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 2.88
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 2.87
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 2.86
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 2.84
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 2.81
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 2.8
Generation of mature lung alveolar epithelial cells from human pluripotent stem cells 2.77
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 2.74
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 2.7
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 2.69
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 2.67
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 2.61
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 2.6
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 2.6
Stem and effector CD8 T-cells from human cancers 2.56
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 2.54
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 2.53
TOP2B disturbed the quality of human oocytes with advanced maternal age 2.45
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 2.44
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 2.44
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 2.41
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 2.28
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 2.28
RNA-Seq in neutrophils from Antiphospholipid Syndrome 2.24
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 2.19
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 2.18
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 2.17
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 2.06
Epigenetic reprogramming of melanoma cells by vitamin C treatment 2.02
Enhancer activation during EGF response 1.96
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 1.93
Transcriptome Profiling of Human Primary Monocytes 1.89
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 1.88
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 1.84
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 1.8
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 1.8
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 1.75
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 1.72
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 1.67
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 1.66
Epigenomic conservation of transposable element silencing [RNA-seq] 1.63
Epigenomic conservation of transposable element silencing 1.63
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 1.61
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 1.61
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 1.59
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 1.59
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 1.56
Ribosomal protein RPL26 is the principal target of UFMylation 1.56
Zika virus infection reprograms global transcription of host cells to allow sustained infection 1.51
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 1.45
SNHG5 siRNA knock down in HCT116 cells 1.43
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 1.42
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 1.42
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 1.39
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 1.37
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 1.37
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 1.36
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 1.34
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 1.29
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia [RNA-seq] 1.29
DHX36 is the missing link to understand RNA G-quadruplex structures, mRNA stability, and translation [RNA-seq] 1.29
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 1.28
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 1.21
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 1.18
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 1.18
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 1.14
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 1.11
RNA expression analysis upon JMJD1C depletion 1.11
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 1.07
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 1.05
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 1.01
Modulation of nonsense-mediated decay by rapamycin 0.97
Transcriptome analysis of human lung epithelial cells 0.97
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 0.97
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 0.93
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.9
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.9
RNA-Seq in PWS iPSC-derived neurons 0.85
Transcriptional changes in lymphoma cells induced by LSD1 depletion 0.82
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 0.82
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 0.8
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 0.78
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 0.77
Microprocessor mediates transcription termination in long noncoding microRNA genes 0.77
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 0.77
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 0.77
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 0.75
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 0.75
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.73
RNA sequencing of T-ALL (COG study) 0.72
Analyses of T-ALL (COG study) 0.72
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 0.71
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 0.71
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.7
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 0.65
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 0.63
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 0.6
RNA-seq of primary patient AML samples 0.55
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 0.46
Leucegene: AML sequencing (part 6) 0.45
AMPK signaling for naïve pluripotency 0.44
AMPK signaling for naïve pluripotency [Hs] 0.44
A MYC/GCN2/eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer 0.43
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 0.43
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 0.43
Expression profiles of the four human major ectodermal lineages 0.41
0.4
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 0.31
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.28
Transcriptome-wide modulation of splicing by the exon junction complex 0.24
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.19
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.19
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 0.15
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.12
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 0.11
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.11
RNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls 0.11
Transcriptome analysis of peripheral blood monocytes 0.09
RNA transcriptome analysis during HSV-1 infection 0.08
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.05
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 0.04
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 0.04
ADAR1-editing of cellular and measles virus-derived duplex RNA 0.03
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 0.03
Gene expression changes due to PARP knockdown in human cells 0.01
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.01


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