Gene Query: KLHL7

Dataset Description Geneva Score
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 75.23
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 75.23
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 58.78
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 39.78
RNA sequencing of BT142 and TS603 cell lines 33.1
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 33.1
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 21.89
MULTI-seq: Universal sample multiplexing for single-cell RNA sequencing using lipid-tagged indices 21.71
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 20.3
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 19.74
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 18.15
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 17.78
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 17.7
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 17.37
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 16.78
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 16.73
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 16.73
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 16.71
RNA sequencing analysis of human embryonic stem cells and axial progenitors 16.55
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 15.31
Differential gene expressions in the heart of hypertrophic cardiomyopathy patients 15.24
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 14.88
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 14.67
Transcriptomic profiling of HeLa cells infected with Salmonella Typhimurium 13.69
RNA-sequencing of formalin fixed human primary melanoma tissue 13.56
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 12.6
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 12.59
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 12.22
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 12.07
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 11.88
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 11.51
RNA-Seq from early time points in the kidney differentiation protocol 11.46
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 11.2
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 10.96
Differentially expressed vascular development genes for iPSC-ECs from CDI 10.49
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 10.47
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 10.45
Differential analysis of gene regulation at transcript resolution by RNA-Seq 10.23
Differential analysis of HOXA1 in adult cells at isoform resolution by RNA-Seq [Illumina] 10.23
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 10.07
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 10.0
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 10.0
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 9.97
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 9.95
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 9.95
Effect of disulfiram treatment on pediatric high grade glioma 9.83
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 9.54
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 9.43
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 9.38
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 9.38
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 9.37
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 9.37
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 9.21
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 9.18
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 9.11
HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma associated herpesvirus ORF57 protein and host pre-mRNA metabolism 8.95
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 8.77
Zika infected neural stem cells 8.54
Transcriptome analysis of Zika infected neural stem cells 8.54
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 8.46
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 8.4
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 8.34
MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts 8.31
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 8.18
DIGIT regulates endoderm differentiation of human embryonic stem cells 8.11
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 8.05
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 7.86
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 7.86
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 7.78
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 7.74
Total RNA-seq in ALL-SIL upon JQ1 inhibition 7.7
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 7.66
Small-molecule targeting of brachyury transcription factor addiction in chordoma 7.59
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 7.48
Transcriptome analysis of kidney organoids 7.38
MYOD Remodeling of the Genome Architecture during Myogenic Conversion of Somatic Cells 7.38
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 7.28
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 7.25
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 7.17
Novel Targeting of Transcription and Metabolism in Glioblastoma 7.16
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 7.15
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 7.11
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 7.11
Oncogenic MYC induces a dependency on the spliceosome in human cancer 7.11
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 7.1
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 6.96
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 6.94
Control of prostate tumour growth by the long non-coding RNA GHSROS 6.93
LIN28A Over-expression RNAseq 6.9
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 6.85
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 6.8
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 6.8
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 6.47
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 6.41
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 6.41
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 6.4
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 6.37
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 6.37
LNCaP treated with iBET 6.34
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 6.29
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 6.24
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 6.13
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 6.13
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 6.06
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 6.02
RNA Sequencing of Human iPS derived Cardiomyocytes 5.92
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 5.91
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 5.89
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 5.89
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 5.86
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 5.83
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 5.81
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 5.76
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 5.72
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 5.71
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 5.66
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 5.64
RNA-seq analysis of differentiating human erythroblasts 5.62
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 5.58
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 5.57
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 5.54
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 5.53
AMPK signaling for naïve pluripotency 5.53
AMPK signaling for naïve pluripotency [Hs] 5.53
Radiation enhances melanoma response to immunotherapeutic and synergizes with benzodiazepines to promote improved anti-tumor activity 5.48
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 5.45
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 5.4
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 5.4
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 5.36
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 5.36
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 5.34
The Human Testis Cell Atlas via Single-cell RNA-seq 5.33
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 5.33
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 5.25
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 5.22
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 5.22
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 5.21
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 5.19
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 5.16
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 5.16
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 5.14
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 5.11
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 5.11
PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells 5.1
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 5.06
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 5.01
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 5.01
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 5.01
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 4.91
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 4.88
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 4.85
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 4.85
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 4.83
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 4.79
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 4.78
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 4.77
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 4.75
Re-Wiring 3D Nuclear Architecture by a Single Transcription Factor during Somatic Cell Reprogramming 4.74
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 4.73
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 4.72
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 4.67
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 4.67
Entrectinib Resistance in a Neuroblastoma Xenograft Model 4.65
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 4.59
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 4.58
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq] 4.54
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression 4.54
Polycomb complexes associate with enhancers to promote oncogenic transcriptional programs in cancer 4.51
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 4.47
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 4.47
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 4.47
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 4.46
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 4.46
Role of microRNAs in the interaction between Salmonella and the host cell 4.46
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 4.46
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 4.44
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 4.44
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 4.42
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 4.4
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 4.29
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 4.27
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 4.26
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 4.24
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 4.24
BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage (Gene expression profiling in several tetrapod species, bulk tissue RNA-seq) 4.22
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 4.17
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 4.16
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 4.14
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 4.13
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 4.12
Hijacking of stress response machinery by oncogenes in acute leukaemia 4.12
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 4.1
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 4.1
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 4.07
Effect of PRDM11 depletion in U2932 cells 4.04
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 4.03
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 4.01
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 4.01
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 4.0
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 3.99
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 3.99
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 3.96
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 3.95
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 3.89
RNA-seq analysis of RALD iPSCs after in vitro differentiation 3.88
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 3.87
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 3.86
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 3.85
Effect of circPTPRM on the biological behaviors of hepatocellular carcinoma cells in vitro and its clinical significance. 3.82
The effect of Abl kinases on non-small cell carcinoma global transcriptome 3.79
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 3.77
Hypoxic transcriptome of SQ20B human head and neck cancer cells 3.76
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 3.76
Comprehensive comparative analysis of 5’ end RNA sequencing methods 3.76
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 3.73
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 3.71
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 3.71
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 3.69
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 3.68
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 3.68
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 3.66
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 3.66
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 3.66
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 3.62
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 3.61
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs 3.61
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 3.61
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 3.58
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 3.54
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 3.53
SLIGRL-induced gene expression changes in NHEK cells 3.53
ETV7 and interferon response 3.52
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 3.52
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 3.52
Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma 3.51
Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma [RNA-Seq] 3.51
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 3.51
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 3.51
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 3.51
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 3.49
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 3.46
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 3.43
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 3.4
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 3.4
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 3.4
Primate-specific gene TMEM14B promotes cortical expansion and folding 3.4
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [GRO-seq II] 3.4
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 3.39
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 3.39
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy 3.39
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 3.37
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 3.34
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 3.34
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 3.33
Gene expression in GBM with Cav3.2 inhibition 3.26
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 3.25
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 3.24
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 3.24
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 3.22
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 3.22
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 3.22
Epigenetic reprogramming of melanoma cells by vitamin C treatment 3.18
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 3.18
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 3.18
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 3.18
Expression level comparison under dividing and quiescent states in human primary fibroblasts 3.17
FOXP2's impact on the primate transcriptome 3.15
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 3.13
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 3.11
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 3.1
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 3.1
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 3.07
Developmental stage specific chromosome architecture in human erythroid cells 3.07
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 3.03
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 3.03
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 3.02
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 3.02
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 3.01
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 3.01
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 3.0
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 2.99
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 2.99
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 2.97
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 2.97
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 2.94
Ebola virus (EBOV) infection of ARPE-19 cells 2.94
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 2.94
PNET animal model: new insights (II) 2.93
RNA sequencing of heart samples of myotonic dystrophic (DM1) patients 2.9
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 2.86
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 2.83
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 2.8
Total RNA sequencing of APC mutant and wt colonic organoids 2.77
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 2.77
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 2.77
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance 2.76
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 2.75
MAIT cell RNA sequencing 2.74
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 2.65
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 2.64
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 2.63
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 2.63
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 2.62
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 2.61
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 2.55
Impact on erythroid progenitor type on erythroid differntiation 2.54
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 2.49
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 2.48
Role of FGFR1 in neuronal devlopment 2.37
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 2.36
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 2.35
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 2.35
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 2.34
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 2.33
scRNASeq analysis of cycling cardiomyocytes 2.32
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 2.29
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 2.27
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 2.27
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.26
Tracing the temporal-spatial transcriptomic landscapes of the human fetal digestive tract by single cell RNA-seq analysis [adult tissues] 2.26
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 2.26
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 2.22
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 2.22
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 2.21
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 2.2
Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region 2.19
Argonaute proteins couple chromatin silencing to alternative splicing 2.18
Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) 2.18
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 2.14
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 2.14
In vitro modeling of human germ cell development using pluripotent stem cells 2.14
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 2.13
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 2.13
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 2.13
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 2.12
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 2.11
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 2.11
RNAseq of T-ALL upon long non coding rna purturbation 2.11
Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile 2.09
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 2.09
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 2.09
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 2.08
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 2.08
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 2.08
HEK293 TFAM Knockout Expression Study 2.07
Dilated cardiomyopathy vs Myocarditis 2.07
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 2.04
A single-cell transcriptome atlas of the human pancreas 2.03
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 2.03
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 2.0
Gene expression profiling of iPSC-derived cardiomyocytes with BAG3 mutations 1.95
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 1.95
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 1.93
Dissecting neural differentiation regulatory networks through epigenetic footprinting 1.92
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 1.91
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 1.9
LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines 1.88
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 1.87
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 1.87
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 1.85
RNA-sequencing of human peripheral blood mononuclear cells (PB MNCs) and induced neural progenitor cells derived from PB MNCs 1.82
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 1.82
Transcriptomic responses to Ivacaftor and prediction of Ivacaftor clinical responsiveness 1.82
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 1.81
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 1.81
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 1.8
Identification of a LIF-responsive replication-competent human β cell 1.78
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and SMAD4 Y95 Mutation Transcriptomes 1.78
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 1.77
GATA3 enhances the neurogenic potential of primary human astrocytes after traumatic injury [exp2] 1.75
LINE-2 transposable elements are a source of functional human microRNAs and target sites 1.73
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.71
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 1.7
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 1.7
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 1.7
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 1.67
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 1.64
Zika virus directly infects human peripheral neurons and induces cell death 1.63
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 1.62
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 1.61
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 1.61
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 1.6
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [H1 RNA-seq] 1.6
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 1.56
The transcriptomic landscape of MAIT cell development in the thymus (C006 RNAseq data set) 1.55
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 1.55
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 1.52
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 1.52
Integrated epigenomic and transcriptomic profiling of terminal human erythropoiesis [TMCC2] 1.51
Functional significance of the HIV-1 Tat signature amino acid residues 1.49
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 1.49
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 1.46
Novel Non-catalytic Substrate-selective p38α-specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-inflammatory Activity 1.45
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 1.45
FGF2 regulation of gene expression in stable inducible Neurons 1.44
Transcriptional dependencies in diffuse intrinsic pontine glioma 1.43
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 1.4
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 1.4
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.39
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 1.38
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 1.38
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.35
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 1.34
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 1.32
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 1.32
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 1.29
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 1.29
Direct Isolation and Characterization of Human Nephron Progenitors. 1.25
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 1.24
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 1.22
KSDM1b Role in Ewing Sarcoma 1.21
Repurposing of promoters and enhancers during mammalian evolution 1.2
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 1.19
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 1.17
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 1.11
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 1.11
Gene expression for surgically treated pancreatic cancer after one neoadjuvant vaccine dose 1.04
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 1.03
Effects of transcription on genome - nuclear lamina interactions 1.02
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 1.02
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.01
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.01
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 1.01
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 1.0
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 1.0
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 0.95
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 0.95
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 0.94
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 0.88
Induced DNA demethylation, genome instability and transcription 0.88
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 0.83
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 0.79
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 0.78
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 0.78
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.76
The MEF2B Regulatory Network 0.75
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 0.72
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 0.72
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 0.71
Genome-wide mapping of TEL-AML1 targets in acute leukemia 0.7
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.67
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 0.65
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 0.62
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 0.61
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 0.61
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.59
Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels 0.58
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 0.58
Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing 0.54
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 0.54
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 0.51
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 0.51
BMS-470539 on human synovial fibroblasts 0.49
O-glcnAc reprograms cellular energetics 0.47
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 0.47
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.45
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.44
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq 0.42
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 0.41
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 0.41
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 0.4
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 0.4
Identification of miRNA-mRNA regulatory network for Human Atrial Aging [mRNA] 0.38
Identification of miRNA-mRNA regulatory network for Human Atrial Aging 0.38
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 0.35
RNAseq analysis of ruxolitinib treated breast cancers 0.35
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.31
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.31
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 0.28
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 0.27
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 0.27
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 0.27
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.27
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 0.26
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 0.25
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.22
The interplay between SOX4 and SMAD3 in the context of breast cancer 0.21
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 0.21
The chromatin modifier CHD8 targets autism risk genes during human neurodevelopment  0.21
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 0.19
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 0.19
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 0.19
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 0.17
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.16
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 0.16
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.16
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.15
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 0.14
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.09
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 0.09
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 0.09
Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells 0.08
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.06
hNSCs siRNA NOVA2 0.06
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.04
SF3B1 Degron knockdown RNA-seq 0.02
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.02
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.01
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.01
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 0.0


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