Gene Query: KRAS

Dataset Description Geneva Score
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 44.54
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 44.54
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 43.53
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 36.44
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 34.7
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 32.53
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 31.58
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 31.58
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 29.86
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 26.34
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 25.43
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 23.12
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 22.49
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 20.96
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 20.96
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 20.35
RNA-Seq analysis of breast cancer cells after shikonin treatment 19.94
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 19.67
Differentially expressed genes post knock down of lincDUSP26 19.24
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 19.12
Human cell line and subcutaneous tumor 18.99
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 18.89
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 18.59
Generation of KRAS signatures using immortalized isogenic lung cells. 18.18
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 17.65
Nrf2 regulated genes in A549 cells 17.31
Identification of Nrf2 regulated genes by RNA sequencing 17.31
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 17.16
Gene expression profiling of leukemia cells following asparagine depletion 16.76
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 16.64
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 16.59
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 16.56
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 16.06
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 15.8
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq] 15.57
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 15.23
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 14.91
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 14.72
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 14.72
RNA-seq in transgenic cells 14.33
Statins modulate endothelial transcriptional profile by inhibiting EZH2 14.18
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 13.99
HNRNPL and its RNA Targets in Prostate Cancer 13.99
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 13.91
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 13.9
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 13.71
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 13.71
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 13.25
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 12.88
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 12.83
Downregulation of DDX5/DDX17 and REST 12.78
A prostate cancer chromatin interaction map 12.5
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 12.26
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 12.09
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 12.06
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 12.06
Discovering the anti-cancer potential of non-oncology drugs by systematic PRISM profiling 12.04
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 12.02
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 11.91
Transcriptome analysis of U87 cells upon LINC00152 knockdown 11.84
Resistance to BET inhibitor leads to new therapeutic vulnerabilities in castration resistant prostate cancer 11.76
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 11.74
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 11.62
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 11.56
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 11.22
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 11.2
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 11.06
Antibody-Mediated Inhibition of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity 10.88
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells 10.84
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 10.73
Identifying the molecular mode of action of itraconazole in colorectal cancer 10.69
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 10.6
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 10.52
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 10.5
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 10.5
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 10.49
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 10.49
Effect of PBK knockdown on C4-2 cell transcriptome 10.38
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 10.24
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 10.24
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 10.23
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 10.21
Global gene expression differences between blood- and lymphatic-specific human dermal microvascular endothelial cells 10.17
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 10.17
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 9.97
RIG-I and MDA5 fRIP during KSHV lytic reactivation 9.87
SLIGRL-induced gene expression changes in NHEK cells 9.86
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 9.82
RNA-seq analyses of human prostate cancer cells 9.78
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 9.75
Transcriptomic analysis of human tonsillar TFH subsets 9.73
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 9.72
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 9.68
The interplay between SOX4 and SMAD3 in the context of breast cancer 9.59
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 9.59
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 9.57
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 9.51
m6A-dependent regulation of messenger RNA stability 9.49
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 9.43
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 9.43
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 9.41
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 9.28
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 9.25
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 9.19
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 9.14
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 9.11
Genome-wide functional assessment of enhancer activities in the human genome 9.11
hnRNP C is a key regulator of protein synthesis in mitosis 9.1
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 9.1
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 9.05
Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms 9.02
Silencing SPIB in attached and floating state of H1703 lung cancer cells 9.02
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 8.91
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 8.85
Conservative alteration of chromosomal expression pattern across human solid tumor types 8.83
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 8.79
Oncogenic MYC induces a dependency on the spliceosome in human cancer 8.78
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 8.77
MEIS1 regulates hematopoiesis in hPSCs 8.61
Effect of circPTPRM on the biological behaviors of hepatocellular carcinoma cells in vitro and its clinical significance. 8.58
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 8.55
Chromatin-informed inference of transcriptional programs in gynecologic cancers 8.55
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 8.53
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 8.52
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 8.51
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 8.48
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 8.44
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 8.44
Ribosomal footprinting of MDA-Parental and MDA-LM2 8.4
The cohesin release factor WAPL restricts chromatin loop extension. 8.38
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 8.38
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 8.38
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 8.32
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 8.26
Primate transcript and protein expression levels evolve under compensatory selection pressures 8.26
Targeting MTHFD2 in Acute Myeloid Leukemia 8.23
Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13 8.21
Ribosomal footprinting of CN34-Parental and CN34-LM1a 8.21
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 8.2
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 8.17
Novel Targeting of Transcription and Metabolism in Glioblastoma 8.15
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 8.14
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 8.13
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA 8.1
Transcriptomes change differerntly in differernt cancer cells upon EPZ-6438 treatment 8.06
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 8.04
scRNASeq analysis of cycling cardiomyocytes 8.03
MYC dependent mRNA translation shapes gene expression and cell biology 7.98
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 7.98
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 7.97
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 7.95
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 7.9
RNA-seq of RKO cells with cTAZ KO or putback 7.89
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 7.84
Gene expression analysis of the impact of TDP-43 knockout in human cells. 7.84
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 7.74
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 7.73
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 7.71
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 7.7
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 7.69
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 7.64
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 7.64
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 7.64
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 7.64
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 7.63
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 7.63
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 7.6
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 7.6
RNA sequencing data of whole blood cells of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women 7.49
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 7.49
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 7.44
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 7.43
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 7.42
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 7.42
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 7.4
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 7.38
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 7.29
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 7.22
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 7.21
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 7.18
Transcriptomic analyssis following EHMT1/2 inhibition 7.17
SUV420H2 knockdown in PANC-1 7.09
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 7.07
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 7.06
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 7.04
Tracing Enhancer Networks using Epigenetic Traits (TENET) 7.01
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 7.01
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 7.01
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 7.0
Co-regulation of splicing by Rbfox1 and hnRNP M 6.98
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 6.98
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 6.95
Intron retention induced by microsatellite expansions as a disease biomarker. 6.92
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 6.89
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 6.88
Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells 6.87
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 6.82
Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice 6.81
Effect of PRDM11 depletion in U2932 cells 6.78
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 6.76
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 6.74
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 6.73
Evolved Labels of Placental Invasion in Human and Bovine Endometrial Stroma 6.72
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 6.71
Comprehensive comparative analysis of 5’ end RNA sequencing methods 6.68
Molecular Criteria for Defining the Naive Human Pluripotent State 6.67
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 6.67
Gene expression profiling in metabolically heterogeneous human lung tumors 6.66
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 6.63
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 6.63
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 6.54
Global response to chemotherapy-induced apoptosis 6.53
Identification of monocyte-like precursors of granulocytes as a mechanism for accumulation of PMN-MDSC in cancer 6.52
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 6.51
Transcriptome profiling of 5 human adenocarcinoma cell lines 6.5
N6-methyladenine DNA Modification in Glioblastoma 6.49
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 6.49
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 6.48
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 6.48
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 6.44
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 6.44
RNA seq_PDX2_SHP099 6.42
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 6.4
Systematic discovery of endogenous human ribonucleoprotein complexes 6.39
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 6.38
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 6.36
RNA-seq of naive and primed ES cells 6.28
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 6.22
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 6.18
Expression data from miR340 overexpressing human A549 cells 6.17
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 6.1
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 6.1
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells with PolyIC treatment 6.05
Zone dependent distinctive gene expression profile of the normal human liver tissue 5.95
Hepatocyte maturation 5.94
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 5.89
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 5.88
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 5.88
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 5.86
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 5.84
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 5.79
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 5.69
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 5.68
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 5.68
Expression level comparison under dividing and quiescent states in human primary fibroblasts 5.67
Splicing and epigenetic factors jointly regulate epidermal differentiation 5.66
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 5.53
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 5.53
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 5.52
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 5.5
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 5.48
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 5.45
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 5.43
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 5.41
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 5.41
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 5.39
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 5.38
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 5.37
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 5.34
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 5.34
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 5.33
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 5.31
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 5.28
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 5.28
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 5.27
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 5.25
O-glcnAc reprograms cellular energetics 5.21
RNA-Seq with and without RNase treatment in PCa cell lines 5.19
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 5.18
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 5.18
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 5.16
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 5.15
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 5.11
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 5.1
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 4.87
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 4.86
SERPINA3- a novel keratinocyte differentiation promotor mediates epidermal barrier repair response in psoriatic lesion 4.84
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 4.84
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 4.82
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 4.8
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 4.8
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 4.8
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 4.79
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 4.75
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 4.73
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 4.66
Transcription elongation regulates genome 3D structure 4.59
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 4.57
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 4.56
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 4.53
Electronic cigarettes 4.5
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 4.45
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 4.41
mRNA expression in human DAOY cells 4.38
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 4.38
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 4.38
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 4.38
A transcriptome dataset revealing the molecular features of breast cancer stem cells 4.38
Hypoxic transcriptome of SQ20B human head and neck cancer cells 4.36
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 4.34
MYCL and EP400 are required for Max and MCPyV mediated gene activation 4.3
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 4.3
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 4.3
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 4.29
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 4.28
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 4.28
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 4.26
RNA sequencing analysis of selumetinib-resistant CRC cells lines 4.25
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 4.2
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 4.11
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 4.08
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 4.06
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 4.06
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 4.06
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 4.06
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 4.04
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 3.96
RNA-sequencing analysis of CD4 T cells following ipilimumab therapy 3.91
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 3.9
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 3.87
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 3.83
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 3.76
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 3.76
RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq] 3.74
Effect of drugs on transcriptomic profiles 3.72
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 3.71
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 3.69
Integrative analysis of RNA, translation and protein levels reveals distinct regulatory variation across humans 3.68
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 3.68
RNA-seq of MDA-MB-231 cells with TET1 knockout 3.67
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 3.56
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 3.56
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 3.56
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 3.53
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 3.5
RNAseq in Alzheimer's Disease patients 3.5
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 3.47
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 3.43
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 3.39
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 3.39
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 3.38
Transcriptome analysis of peripheral blood monocytes 3.36
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 3.19
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 3.19
Determination of tRNA aminoacylation levels by high throughput sequencing 3.18
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 3.15
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 3.08
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 3.05
Defective structural RNA processing in relapsing-remitting multiple sclerosis 3.0
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 2.96
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 2.96
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 2.96
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 2.96
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 2.95
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 2.93
Regulation of protein translation during mitosis 2.88
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.88
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 2.79
Transcriptional changes in lymphoma cells induced by LSD1 depletion 2.79
Copper Regulation of HIF-1 Transcription Activity 2.77
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 2.77
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 2.76
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [H1 RNA-seq] 2.76
Gene expression activation in CLL mediated by MSCs contact 2.75
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 2.75
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 2.74
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 2.73
Mitochondrial dsRNA triggers antiviral signalling in humans 2.67
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 2.65
Transcriptome analysis upon C6orf203 silencing 2.61
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 2.59
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 2.54
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 2.51
KSDM1b Role in Ewing Sarcoma 2.49
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 2.46
Interaction between mitoNEET and NAF-1 in cancer cells 2.46
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 2.44
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 2.43
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 2.36
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 2.34
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 2.34
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 2.29
Transcriptome of diurnal human blood neutrophils 2.24
Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1 2.24
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 2.23
Transcriptome-wide modulation of splicing by the exon junction complex 2.22
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 2.21
Transcriptome-wide response to synthetic chromatin protein PcTF 2.19
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 2.14
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 2.1
Exploring ILF2 regulatory genes by next-generation sequencing 2.1
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 2.05
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 2.04
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 2.02
Patient-derived organoids (PDOs) model treatment response of metastatic gastrointestinal cancers. 2.0
Transcriptional landscape changes during human embryonic stem cell derivation 1.99
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 1.98
WNT signaling memory is required for ACTIVIN to function as a morphogen 1.94
Identification of differentially expressed circRNA in gallbladder cancer compared with matched normal tissue 1.94
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.92
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 1.9
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 1.89
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 1.83
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 1.81
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 1.8
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 1.79
Transcriptome of human ILC2s; primary vs IL-1b-primed 1.79
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 1.77
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 1.76
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.75
Expression charcaterization of an internal protocol developed to differentiate RPE cells 1.7
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 1.68
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 1.62
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 1.61
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 1.6
CD74 role in transcription regulation 1.58
CD74 role in transcription regulation [RNA-seq] 1.58
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 1.57
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 1.55
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 1.55
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 1.55
Intrinsic Plasma Cell Differentiation Defects in BENTA Patient B cells 1.5
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 1.47
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.45
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 1.43
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 1.43
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 1.42
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 1.42
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 1.34
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution 1.28
Effects of transcription on genome - nuclear lamina interactions 1.23
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 1.23
HBEC-shp53-PCHD7 1.19
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.17
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.17
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.09
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 1.06
Positively selected enhancer elements endow tumor cells with metastatic competence 1.03
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 1.01
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 1.0
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 1.0
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 0.98
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 0.96
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: Comparison of gene expression profiling approaches 0.82
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: Comparison of gene expression profiling approaches [RNA-Seq] 0.82
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.77
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.73
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.7
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 0.7
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 0.7
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 0.68
FBXW7 modulates stress response by post-translational modification of HSF1 0.68
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.67
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 0.67
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 0.65
nELAVL HITS-CLIP in Alzheimer's Disease patients 0.65
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 0.64
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 0.64
Aneuploidy triggers an immune response 0.63
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.62
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.62
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.58
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.58
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 0.57
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation 0.53
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.52
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.52
The role of the Calcium-Sensing receptor in colorectal cancer 0.45
RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) 0.44
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 0.42
Compare of gene expression between p16INK4A positive and negative regions of colon cancer from five patients 0.42
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 0.39
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression 0.36
A MYC/GCN2/eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer 0.35
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 0.34
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.33
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.32
Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants 0.3
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.27
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 0.27
Profiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis 0.23
EZH1/SUZ12 complex positively regulates the transcription of NF-κB target genes via interaction with UXT 0.23
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 0.22
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 0.21
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 0.21
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 0.2
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.18
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 0.17
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 0.17
BACH2 in human plasma cell fate decision 0.17
Modulation of nonsense-mediated decay by rapamycin 0.17
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 0.17
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 0.13
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 0.13
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 0.11
Ribosomal protein RPL26 is the principal target of UFMylation 0.06
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 0.05
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.04
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.01
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.0


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation