Gene Query: LGALS3

Dataset Description Geneva Score
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 401.58
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 81.55
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 74.05
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 74.05
WRN knockout effects upon gene expression in SW48 and OVK18 71.04
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 68.19
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 65.96
Allogeneic mature human dendritic cells generate superior alloreactive regulatory T cells in the presence of IL-15 62.47
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 60.37
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 57.18
LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines 56.36
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 50.22
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 47.63
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 47.63
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 45.68
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 45.43
Circular RNA expression signature of low-glucose-treated MIA PaCa-2 cells 45.0
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 43.88
Next Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs 43.21
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 42.88
Altering cancer transcriptomes using epigenomic inhibitors 42.88
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 42.17
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 41.26
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 40.34
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 40.15
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 39.56
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 38.97
Comparing gene expression in iPSC derived RPE from control and AMD donors 38.79
Targeting MTHFD2 in Acute Myeloid Leukemia 38.34
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 36.94
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 36.35
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 36.3
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 36.3
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 36.18
Cellular gene expression during Hepatitis C Virus replication revealed by Ribosome profiling 35.46
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 35.04
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 34.93
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 34.44
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 33.45
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) 33.32
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 33.13
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 33.04
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 33.04
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 32.5
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 32.34
RNA-seq analyses of human prostate cancer cells 32.24
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 32.24
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 32.2
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 32.17
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 31.6
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 31.47
Effect of BMP inhibition or stimulation of primary human keratinocytes 31.41
Single-cell ID-seq identifies BMP signaling as a driver of a late stage epidermal differentiation program. 31.41
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 31.33
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 31.31
RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma 31.14
Transcription elongation factors are in vivo-specific cancer dependencies in glioma 31.14
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 31.11
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 30.98
High level DNA repair gene expression in human ES cells 30.51
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 30.47
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 30.47
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 30.31
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 30.26
PNET animal model: new insights (II) 30.21
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 29.53
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 29.42
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 29.35
MYCi361 regulates MYC target genes 28.93
Modeling Trilateral Retinoblastoma using Human Embryonic Stem Cells 28.82
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 28.45
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 27.32
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 26.99
Impact on erythroid progenitor type on erythroid differntiation 26.43
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 26.23
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 26.19
Gene profiling of human adult and pediatric liver cancer cells 25.96
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 25.93
CircRNAome diversity in human mature B-cells, T-cells and monocytes 25.86
Hepatitis C virus functionally sequesters miR-122 25.43
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 25.43
Postnatal lipids drive hepatocyte maturation 25.2
Global gene expression profiling from LeuCAG3'tsRNA depleted- HeLa and HCT-116 cell lines through 50 base pair paired-end RNA-seq 25.19
Control of prostate tumour growth by the long non-coding RNA GHSROS (LNCaP) 25.14
RNA-seq Transcriptome Analysis of AD169 and AD169-ΔUL26 infected MRC5 fibroblasts. 25.12
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 25.04
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines 25.0
Genomic analysis of human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast 24.8
mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast 24.8
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 24.77
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 24.77
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 24.43
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 24.36
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 24.33
Identification of a LIF-responsive replication-competent human β cell 24.2
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 24.14
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 24.09
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 24.0
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 24.0
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 23.79
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 23.53
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 23.51
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 23.32
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 23.06
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 23.06
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 22.91
SF3B1 Degron knockdown RNA-seq 22.81
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 22.03
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 21.85
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 21.69
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 21.68
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 21.58
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 21.52
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 21.52
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 21.49
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 21.49
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 21.41
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 21.41
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 21.14
Single-nucleotide-resolution mapping of HBV promoters using CAGE 20.99
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 20.96
Ro60-knockout cells 20.87
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 20.82
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 20.82
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 20.79
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 20.75
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 20.74
Novel Targeting of Transcription and Metabolism in Glioblastoma 20.65
Transcriptomes change differerntly in differernt cancer cells upon EPZ-6438 treatment 20.58
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 20.54
Transcriptomic analysis of human tonsillar TFH subsets 20.51
Non-coding regions are the main source of tumor-specific antigens 20.44
Non-coding regions are the main source of tumor-specific antigens [human] 20.44
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 20.36
Comparative Analysis of the Transcriptome of Latent Autoimmune Diabetes (LADA) Patients from Eastern China 20.29
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 20.16
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 20.04
High-efficiency RNA-based reprogramming of human primary fibroblasts 20.02
Crizotinib v. DMSO in SW480 cells 19.83
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing 19.82
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing [RNA-Seq] 19.82
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 19.81
Transcriptomic and gene ontology profiling of the human corneal cell types 19.76
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis 19.52
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 19.51
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 19.5
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 19.5
Expression level comparison under dividing and quiescent states in human primary fibroblasts 19.46
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 19.44
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 19.38
Neonatal and adult human testis defined at the single-cell level 19.16
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 19.05
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 18.82
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 18.81
LncRNA-GAS5 negative regulation of YAP-target genes expression 18.77
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 18.71
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 18.7
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 18.7
Interaction between mitoNEET and NAF-1 in cancer cells 18.36
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 18.32
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 18.32
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 18.31
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 18.27
Transcriptome profiling of CXCR2+ neuroendocrine (NE) tumor cells purified from patients' fresh prostate adenocarcinoma 18.13
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 18.1
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 18.07
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 17.96
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 17.96
Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region 17.81
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 17.78
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 17.76
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 17.73
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 17.72
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 17.72
Single-Cell Genotyping of Transcriptomes 17.7
RNA-seq of Single-Cell Genotyping of Transcriptomes 17.7
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 17.51
Differential gene expressions in the heart of hypertrophic cardiomyopathy patients 17.45
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 17.4
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 17.4
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 17.25
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 17.22
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 17.09
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 17.03
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 17.01
Gene expression analysis of dengue-infected cells 16.82
Accurate annotation of human protein-coding small open reading frames 16.8
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 16.77
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 16.75
Tumor exosome integrins determine organotropic metastasis 16.65
The landscape of alternative splicing in aggressive prostate cancers 16.65
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 16.58
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 16.38
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 16.38
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 16.29
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 16.19
A549 cells and MSR-A549 cells 16.19
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 16.17
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 16.17
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 16.0
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 15.92
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 15.9
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 15.86
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 15.86
Patient-derived luminal breast cancer xenografts with progestins 15.82
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 15.82
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 15.77
Transcriptome profiling of Cryptosporidium parvum infected lung and intestinal organoids 15.62
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 15.54
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 15.52
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 15.52
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq] 15.5
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression 15.5
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 15.43
Paxillin regulates genomic networks in prostate cancer [PC3] 15.37
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 15.37
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 15.27
CDK4/6 inhibitor resistance in prostate cancer 15.26
Role of CD133 molecule in WNT response and renal repair 15.14
Identification of gene signature in ascitic fluid-isolated mesothelial cells from high grade serous ovarian cancer patients 15.12
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 15.11
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 15.06
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 15.05
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 14.95
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 14.89
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 14.89
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 14.87
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 14.87
High-throughput sequencing of the human hepatic progenitor cell niche in PSC and HCV. 14.85
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 14.68
Induced DNA demethylation, genome instability and transcription 14.68
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 14.6
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 14.57
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 14.57
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 14.45
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 14.43
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes 14.4
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 14.39
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 14.31
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 14.3
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 14.2
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 14.2
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 14.19
Effect of disulfiram treatment on pediatric high grade glioma 14.14
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 14.13
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 14.1
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 14.1
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 14.07
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 14.03
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 14.03
Expression profiling of etoposide-induced senescent cells 13.93
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_1A_PI3K_RNA-seq] 13.9
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 13.81
CSL RNA-Seq on HKC and SCC cell lines 13.75
CSL 13.75
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 13.63
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 13.63
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 13.58
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 13.57
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 13.55
RNA-seq of CD33 KO and control HSPCs 13.53
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 13.35
Identification of mesothelial-to-mesenchymal gene signature in ascitic fluid-isolated mesothelial cells through RNA-sequencing 13.33
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 13.31
ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq) 13.27
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 13.27
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 13.24
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 13.24
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 13.1
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 13.1
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 12.99
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming 12.85
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 12.84
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 12.84
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate. 12.79
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 12.78
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 12.76
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 12.67
Gene expression changes caused by KRAS in MCF-10A 12.62
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 12.61
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 12.61
Gene expression changes in human melanoma cell lines compared to primary melanocytes 12.46
Proliferation-correlated expression 12.23
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 12.2
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle 12.06
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 12.05
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 12.03
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 11.99
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 11.93
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway 11.89
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 11.88
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 11.74
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 11.74
Chromatin-informed inference of transcriptional programs in gynecologic cancers 11.74
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 11.65
Developmental stage specific chromosome architecture in human erythroid cells 11.65
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 11.62
Characterization of parental and rociletinib-resistant derived H1975 cell lines 11.58
A sister of NANOG regulates genes expressed in pre-implantation human development 11.58
Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms 11.51
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 11.5
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 11.5
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 11.5
EWS-Fli and LNC regulated genes in comparison to GFP samples 11.46
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 11.21
Activity-dependent transcriptional changes in human neurons 11.19
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 11.14
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 11.12
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 11.09
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 11.07
DAOY-Notch1/Notch2 knockout: transcriptome comparison 10.98
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 10.93
10.92
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 10.81
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 10.78
mRNA Sequencing of Human PromoCells Using 3'-directed Digital Gene Expression (3'-DGE) Technique 10.73
Transcriptome of EBV-infected gastric cancer cell lines 10.67
An optimization system for isolating and sequencing of single human colon cancer cells 10.65
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 10.54
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 10.54
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 10.33
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 10.33
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 10.25
Viral infection enhances NK cell activation via Type I dependent pathways and can be utilized to enhance influenza-specific monoclonal antibody therapies 10.07
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 10.03
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 10.01
JAK dependent survival of ALK- ALCL 9.52
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 9.47
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 9.44
High-throughput sequencing of PROMPT-enriched samples. 9.38
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 9.38
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 9.1
LIN28A Over-expression RNAseq 9.07
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 9.04
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 9.0
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 8.93
Functional astrocytes differentiated from hiPSCs 8.72
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues [Total RNA] 8.67
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 8.61
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 8.6
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 8.55
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes 8.4
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq] 8.4
Novel kinase fusion oncogenes in post-Chernobyl radiation-induced pediatric thyroid cancers 8.38
Metabolism as an early predictor of DPSCs aging 8.37
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 8.33
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 8.33
Divergent expression and metabolic functions of human glucuronosyltransferases through alternative splicing 8.28
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 8.25
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 8.25
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 8.19
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 8.06
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 8.06
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 7.99
Changes in human endometrial gland transcriptome over the window of implantation 7.88
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 7.83
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 7.81
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 7.76
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 7.72
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 7.61
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 7.57
7.54
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 7.48
Primate transcript and protein expression levels evolve under compensatory selection pressures 7.47
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 7.42
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 7.42
FOXP3 protects conventional human T cells from premature restimulation-induced cell death 7.34
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 7.28
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 7.21
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 7.17
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 7.16
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 7.16
RNA sequencing analysis of selumetinib-resistant CRC cells lines 7.09
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 7.02
Tracing the temporal-spatial transcriptomic landscapes of the human fetal digestive tract by single cell RNA-seq analysis [adult tissues] 7.02
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 6.98
DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats 6.96
Differential responses of human fetal brain neural stem cells to Zika virus infection 6.88
Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells 6.84
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 6.77
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 6.76
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 6.74
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 6.74
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia 6.62
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 6.51
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 6.5
Total RNA sequencing of APC mutant and wt colonic organoids 6.34
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 6.33
Direct Isolation and Characterization of Human Nephron Progenitors. 6.33
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 6.33
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 6.33
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 6.29
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 6.29
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 6.29
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 6.29
RNA splicing alteration on glioblastoma and normal neural stem cells 6.28
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 6.21
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 5.91
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 5.67
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 5.67
Gene expression profile of multiple myeloma cell lines treated with CB-5083 5.64
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 5.62
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 5.6
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 5.6
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 5.51
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 5.49
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 5.49
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 5.18
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 5.18
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 4.81
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 4.8
Effect of nuclear IL-33 on gene expression 4.78
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 4.75
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 4.63
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 4.63
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 4.61
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 4.51
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 4.42
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 4.39
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 4.3
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 4.26
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 [stranded] 4.19
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 4.17
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 4.17
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 4.11
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 3.98
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 3.93
MAIT cell RNA sequencing 3.9
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 3.88
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 3.87
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 3.83
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 3.83
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 3.78
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 3.75
The Genetic Landscape of Diamond-Blackfan Anemia 3.73
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 3.71
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 3.68
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 3.61
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 3.25
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 3.23
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 3.15
Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy 2.91
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 2.91
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 2.87
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 2.85
Gene expression analysis of human liver progenitor-like cells in culture 2.82
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus 2.77
Transcriptome sequencing identify a recurrent CRYL1-IFT88 chimeric transcript in hepatocellular carcinoma 2.74
Gene expression signatures of innate lymphoid cells from human blood 2.5
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 2.45
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 2.32
An acquired vulnerability of drug resistant melanoma with therapeutic potential 2.27
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 2.27
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 2.22
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 2.17
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 2.17
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 1.9
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 1.84
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 1.8
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 1.76
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  1.75
Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles 1.71
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 1.69
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 1.68
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 1.6
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 1.6
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 1.43
Expression and functions of long noncoding RNAs during human T helper cell differentiation 1.41
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.26
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 1.21
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 1.17
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 1.15
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 1.13
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.97
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 0.81
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 0.81
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 0.81
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.74
Specific molecular signatures underlie response to decitabine in CMML 0.74
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.74
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 0.62
Gene expression of thyroid cancer cell lines 0.53
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 0.43
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells 0.4
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.39
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.39
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 0.35
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and converts them into tumorigenic cells 0.35
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.32
Identification of long noncoding RNAs regulated by p53 0.32
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells 0.31
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells [RNA-seq] 0.31
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 0.24
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.24
Human Treg IFNg/IL-10 subpopulations 0.22
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity 0.14
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 0.11
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 0.11
Glucose inhibits cardiac maturation through nucleotide biosynthesis 0.1
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.09


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