Gene Query: LOXL2

Dataset Description Geneva Score
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 159.08
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 108.3
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 104.41
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 104.41
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 90.98
Rorc disruption in human FG pancreatic cancer cells 86.3
RNA-seq and Microarray in Transcriptome Profiling of Anterior Cruciate Ligament Tears: Implications for Prognostic Biomarkers Discovery 82.86
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 80.94
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 80.94
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 78.14
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 75.97
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 72.5
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 68.91
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 68.09
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 67.93
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 67.17
H1609088 Human RNA-Sequencing 65.73
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 65.56
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 63.23
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 63.23
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 62.31
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 62.31
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 62.02
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq] 61.65
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma 61.65
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 61.35
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 61.0
RNA expression following TMPRSS11B overexpression or depletion 57.86
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 53.91
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 53.89
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 53.89
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 53.85
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 52.96
Genome-wide chromatin analysis of Ewing sarcoma 52.96
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 51.93
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 51.3
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 50.58
Global analyses of the effect of different cellular contexts on microRNA targeting 49.49
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 49.49
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 49.43
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 48.25
Discovering the anti-cancer potential of non-oncology drugs by systematic PRISM profiling 47.96
Maturation of human iNSCs 47.82
Appropriately Differentiated ARPE-19 Cells Regain a Native Phenotype and Similar Gene Expression Profile 47.8
Transcriptional profiles of normal human mature B cells 47.71
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 47.36
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 47.2
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 46.87
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 46.12
EWS-Fli and LNC regulated genes in comparison to GFP samples 44.93
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 44.41
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 43.39
RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines 43.24
RNA-seq in HepG2 and IMR90 cells 43.12
Evolution of a transcriptional regulator from a transmembrane nucleoporin 43.12
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 43.07
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 42.66
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 42.54
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 41.43
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 41.43
RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes 40.37
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 40.07
Spliceosomal disruption of the non-canonical BAF complex in cancer 39.86
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 39.73
Tyrosine Kinase Inhibitor Cardiotoxicity 39.73
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 39.07
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 38.79
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 38.55
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 38.32
Nonpregnant and term pregnant human myometrial tissues 38.32
DJ-1 is dispensable for human stem cell homeostasis 38.15
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 38.07
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 38.07
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 38.05
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 38.04
Comparing effects of perfusion and hydrostatic pressure on human chondrocytes using gene profiles 37.89
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 37.56
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 37.56
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 37.53
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 37.39
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 36.88
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 35.69
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 35.66
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 35.44
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 35.26
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 35.0
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 34.26
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 34.02
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 33.94
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 33.83
Differential expression of genes in AD169-infected MRC5. 33.68
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 33.34
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 33.3
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 33.24
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 33.01
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 32.95
Transcriptome profiling of Caki2 cells re-expressing Polybromo-1 (PBRM1) 32.9
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 32.72
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 32.66
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 32.66
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 32.47
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 32.39
Gene expression analysis in response to hypoxic pathway inhibition 32.36
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 32.36
Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs 32.35
mRNA expression data from ESCs derived by polar body transfer reconstructed embryos (PBTESCs) 32.34
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 32.24
Control of prostate tumour growth by the long non-coding RNA GHSROS (LNCaP) 32.19
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 31.96
Hypoxic transcriptome of SQ20B human head and neck cancer cells 31.36
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 31.3
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 31.3
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 31.08
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 30.9
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 30.9
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 30.66
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 30.48
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 30.48
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 30.43
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 30.4
Mesothelioma xenografts in nude mice: PBS treated versus pirfenidone treated 30.34
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 30.18
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 29.53
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 29.52
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 29.52
NHLRC1 re-expression in cancer cells 29.51
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 29.51
Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes 29.45
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 29.44
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 29.33
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 29.26
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 29.25
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 29.18
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 28.76
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 28.43
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 28.34
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 28.28
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 28.25
MYCi975 regulates MYC target genes 28.04
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 28.03
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 27.99
Modeling Familial Cancer with iPSC Approaches 27.7
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 27.69
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 27.64
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 27.52
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 27.45
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 27.29
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 27.22
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 27.09
Gene expression profile in breast cancer cell lines using RNA sequencing 26.96
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 26.78
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 26.66
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 26.66
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 26.41
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 26.41
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 26.25
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 26.21
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 26.12
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 25.97
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 25.91
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 25.91
CD73 knockdown effect in pancreatic cancer cell lines 25.84
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 25.65
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 25.47
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 25.43
Gene expression in PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition. 25.43
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 25.26
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 25.26
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 25.19
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 25.17
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 25.15
Gene expression analysis of immortalized human liver progenitor-like cells in culture 25.05
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  24.97
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 24.9
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 24.59
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 24.58
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 24.44
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 24.35
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 24.28
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 24.2
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 24.2
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 24.02
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 23.95
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 23.62
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 23.55
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 23.46
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 23.13
RNA-seq of MCF10A cells and CAF 23.01
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 22.79
The Genomic Landscape of Atypical Fibroxanthoma 22.46
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 22.38
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 22.2
Finding missing proteins from epigenetically manipulated human cells 22.19
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 22.17
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 22.12
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 22.08
Fbxo32 mediated gene expression program underlies EMT and metastasis 22.04
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 22.02
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 21.98
RNA-seq of human aneuploid cell lines with Trisomy 21 21.98
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 21.94
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 21.94
Gene expression profile of human iPSC-derived nephron progenitor cells 21.86
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 21.76
MEIS1 regulates hematopoiesis in hPSCs 21.46
Effect of nuclear IL-33 on gene expression 21.39
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq] 21.38
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations 21.38
Genetic-to-epigenetic Therapy for Pancreatic Cancer 21.36
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 21.3
Genome-wide RNA-sequencing (RNA-seq) of benign and malignant prostate cell lines without and with androgen (R1881) stimulation. 21.29
Replicated transcriptome profiling of Normal and Cancerous Prostate Cells [RNA-Seq] 21.17
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 21.08
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 21.08
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 21.05
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 21.02
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 20.99
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 20.91
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 20.87
Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs 20.87
Differential gene expression of human melanoma cells [RNA-seq] 20.69
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 20.69
Morphological and molecular characterization of human dermal lymphatic collectors 20.68
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 20.68
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 20.66
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 20.43
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 20.39
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 20.37
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 20.35
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 20.25
Transcriptomic profile of human embryonic renal corpuscles 20.21
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 20.01
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 19.84
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 19.81
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 19.8
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 19.77
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 19.53
RNA-seq analysis of RALD iPSCs after in vitro differentiation 19.53
Transcriptomes change differerntly in differernt cancer cells upon EPZ-6438 treatment 19.53
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 19.29
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 19.23
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 19.21
MCF10A H-Ras RNA-Seq 19.21
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 19.18
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 19.16
Gene expression changes in human melanoma cell lines compared to primary melanocytes 19.08
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 19.04
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 18.96
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 18.96
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 18.91
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 18.91
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 18.89
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 18.89
Transcriptome profiling of Normal and Cancerous Prostate Cells 18.85
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 18.85
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 18.82
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 18.74
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 18.74
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 18.67
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 18.52
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 18.49
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 18.46
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 18.28
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 18.24
RNA splicing alteration on glioblastoma and normal neural stem cells 18.21
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 18.03
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 17.98
Gene expression patterns define the hepatocyte-like cells derived by different strategies 17.89
Gene expression patterns define the hepatocyte-like cells derived by different strategies [RNA-seq] 17.89
SF3B1 Degron knockdown RNA-seq 17.88
RNA sequencing of GlyH-101-treated MCF-7 cell line 17.69
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 17.63
GCTM-5 positive and negative cells in pancreatic adenocarcinoma cell lines 17.63
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 17.58
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 17.57
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 17.56
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 17.53
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 17.53
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 17.51
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 17.49
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 17.43
Nm-seq finds thousands of modified 2’-O-methylation sites in mRNA with base precision 17.35
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 17.34
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 17.24
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 17.23
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 17.23
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 17.16
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 17.1
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 17.05
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 17.05
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 16.93
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 16.93
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 16.87
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 16.8
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 16.79
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 16.77
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 16.67
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 16.67
TGF-β regulation of miRNA expression in pancreatic cancer 16.65
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 16.63
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 16.63
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 16.54
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 16.5
Global expression profiles in cardiac progenitor cells generated by ISX-9 16.47
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 16.47
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 16.45
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 16.43
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 16.43
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 16.42
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 16.42
RNA Seq of HMVEC under hypoxia 16.42
Endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates 16.42
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 16.39
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 16.36
Combined Genome and Transcriptome Sequencing to Identify Allelic Selection in Epithelial Ovarian Cancer 16.35
Fusion discovery in breast cancer cell line 16.17
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 16.09
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 16.07
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 16.03
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 16.03
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 15.93
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 15.92
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 15.8
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 15.65
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 15.5
A549 cells and MSR-A549 cells 15.5
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 15.46
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 15.44
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 15.41
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 15.41
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 15.4
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 15.37
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 15.33
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 15.3
Zika virus infection reprograms global transcription of host cells to allow sustained infection 15.14
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 14.98
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 14.89
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy 14.85
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 14.83
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 14.81
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 14.79
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 14.79
Nutritional control of protein translation 14.68
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 14.65
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 14.63
KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone 14.63
ARID1A and ARID1B loss in HCT116 and TOV21G cells 14.44
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells 14.36
Gene expression profile difference among renal location in a stone former 14.33
EGR1-controlled transcriptome of T HESCs 14.13
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 14.12
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 14.11
Genome-wide Analysis of Chromatin Interactions in Human Cells 14.11
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 14.1
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 14.1
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 14.04
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 13.98
Human embryonic stem cells in E8 and AKIT culture medium 13.98
Gene expression profiling of human and murine in vitro muscle differentiation 13.79
Short and long-term effects of CDK4/6 inhibition on early stage breast cancer 13.79
Transcriptomic analysis of LSD1 13.58
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 13.45
Expression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions. 13.3
RNA-seq analysis of control and Myc-induced U2OS cells 13.28
The effect of Foxc1 deficiency on undifferentiated and differentiated human primary keratinocytes 12.99
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 12.91
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 12.79
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 12.78
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 12.48
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 12.45
Transcriptome of EBV-infected gastric cancer cell lines 11.86
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 11.83
Postnatal lipids drive hepatocyte maturation 11.74
Gene profiling of human adult and pediatric liver cancer cells 11.18
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 11.12
Proteomics identifies a marker signature of MAPKi resistance in melanoma 11.02
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 11.0
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 10.93
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 10.93
The MEF2B Regulatory Network - RNA-seq data 10.72
The MEF2B Regulatory Network 10.72
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 10.69
6mer seed toxicity in tumour suppressive microRNAs 10.62
Functional astrocytes differentiated from hiPSCs 10.59
RNA-Seq of Breast and Ovarian Cancer Cell Lines 10.57
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 10.48
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 10.39
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 10.36
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 10.28
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 10.25
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 10.05
iPSC derived motor neuron cultures from C9ORF72 carriers 9.97
RNA-sequencing of human tendon after injury 9.62
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 9.6
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 9.6
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 9.46
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 9.45
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 9.45
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 9.4
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 9.4
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 9.08
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 9.08
Transcriptomic analysis of ERR alpha orphan nuclear receptor 8.93
Gene Expression Profiling of WT and KDM3A Knocked out Cell 8.85
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 8.85
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 8.65
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 8.55
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 8.49
Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications 8.42
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 8.35
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 8.27
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 8.2
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 8.15
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 8.04
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 8.02
Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile 7.87
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 7.73
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 7.57
Wide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling 7.51
RNA-seq of cancer cell lines treated with T-025 7.47
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 7.31
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 7.11
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 7.11
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 7.03
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 7.03
Downregulation of LATS kinases alters p53 to promote cell migration 6.91
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 6.81
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 6.73
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 6.7
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 6.68
RNA seq_PDX2_SHP099 6.44
Efficient derivation of microglia-like cells from human pluripotent stem cells 6.41
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 6.36
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 6.06
In search for materials able to be colonized by a normal endothelium: сharacterization and NGS gene expression profiling of human primary endotheliocytes cultivated on electrospun 3D matrices 5.95
Mutations in EBF3 disturb transcriptional profiles and cause intellectual disability, ataxia and facial dysmorphism 5.89
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 5.71
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 5.63
mRNA sequencing of oropharyngeal cancer cell lines 5.62
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 5.6
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 5.54
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 5.5
CHCHD10 gene KO effect in iPSC drived motor neurons 5.5
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 5.4
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 4.99
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 4.94
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 4.93
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 4.93
Expression charcaterization of an internal protocol developed to differentiate RPE cells 4.88
MRTF activates TEAD-YAP target gene expression 4.87
The mRNA expression analysis of psoriasis skin lesion mesenchymal stem cell 4.84
Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines. 4.74
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 4.61
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 4.58
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 4.49
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 4.49
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 4.3
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 4.17
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 4.09
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 4.09
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 4.02
Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells. 3.8
Glucose inhibits cardiac maturation through nucleotide biosynthesis 3.76
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 3.7
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 3.67
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 3.49
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 3.33
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 3.2
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 3.2
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 3.13
Exogenous rescue of KLHL9 in SF210 cell line 3.09
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 2.71
Rate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications 2.55
6mer seed toxicity in viral microRNAs 2.4
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 2.22
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 2.2
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 2.06
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 1.81
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 1.66
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 1.56
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 1.44
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 1.39
An acquired vulnerability of drug resistant melanoma with therapeutic potential 1.15
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 1.15
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 0.98
Gene expression regulated by CSA and CSB in neuroblastoma cell line 0.81
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 0.77
Polycomb complexes associate with enhancers to promote oncogenic transcriptional programs in cancer 0.69
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 0.65
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation 0.59
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 0.53
Engineering Patient-Specific Tissue Implants 0.47
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 0.35
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 0.27
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.22
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 0.16
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 0.12
Gene expression analysis of breast cancer cell-lines 0.1
Gene expression and genome-wide location analysis of breast cancer cell-lines 0.1
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 0.09


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