Gene Query: LOXL4

Dataset Description Geneva Score
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 187.74
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 157.33
TCF21 and Aryl-hydrocarbon receptor gene cooperate to activate a pro-atherosclerotic gene expression program 155.41
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 150.1
The role of the Calcium-Sensing receptor in colorectal cancer 106.4
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 105.83
Expression level comparison under dividing and quiescent states in human primary fibroblasts 101.63
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 87.61
RNA-seq of human fibroblasts after irradiation 80.24
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 76.46
Transcriptome-wide identification of CELF2 functional targets in T cells 73.44
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 68.82
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 64.98
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 64.65
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 64.65
Tumor exosome integrins determine organotropic metastasis 60.72
Survival of pancreatic cancer cells lacking KRAS function 59.14
A role for ZNF598 in post-transcriptional gene regulation 58.5
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 56.66
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 54.57
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 54.16
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 52.41
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 47.98
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 46.89
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 46.89
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 45.9
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 45.55
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 44.53
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 44.19
Regulation of Lipids is Central to Replicative Senescence 43.56
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 43.53
TFAP2C signalling in human fibroblasts 43.29
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 42.32
Generation of trichogenic adipose-derived stem cells by expression of three factors 41.47
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 41.21
Inhibition of TNBC metastasis by Gpx1 39.86
Real-time observation of light-controlled transcription in living cells 39.57
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 39.22
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 39.01
Fbxo32 mediated gene expression program underlies EMT and metastasis 38.91
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 38.55
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 38.12
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 38.11
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 37.87
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 37.65
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 37.13
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 36.44
Comparing gene expression in iPSC derived RPE from control and AMD donors 36.25
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 35.8
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 35.8
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 35.79
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 35.68
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 34.83
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 34.83
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 34.48
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 33.76
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 33.43
MicroRNA targetome analysis during HCMV infection 33.36
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 32.86
Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells 32.77
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 32.35
RNA-Sequencing of HepG2 cells treated with TGFBeta 31.98
Spliceosomal disruption of the non-canonical BAF complex in cancer 31.59
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 31.56
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 31.52
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 31.17
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 30.98
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 30.77
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 30.63
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 30.36
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 30.01
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 30.01
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 29.97
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 29.74
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 29.59
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 29.5
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 29.39
Paxillin regulates genomic networks in prostate cancer [PC3] 29.08
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 28.82
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 28.82
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 28.7
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 28.46
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 28.46
The cohesin complex prevents Myc-induced replication stress 28.09
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 28.09
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 28.09
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 27.43
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 26.83
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 26.75
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 26.75
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 26.7
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 26.7
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 26.7
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 26.67
Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells 26.67
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 26.63
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 26.63
An RNA-centric dissection of host complexes controlling flavivirus infection [RNA-Seq] 26.48
An RNA-centric dissection of host complexes controlling flavivirus infection 26.48
Modulation of ESRP2 and MBNL2 in normal kidney and clear cell renal cell carcinoma cell lines for analysis of stability programs 26.24
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 25.45
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 25.37
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 25.17
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 25.06
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 25.03
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 24.85
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 24.85
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 24.77
Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2 24.3
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 24.16
RNA seq analysis of human Fetal and adult derived Enterospheres 23.82
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 23.79
Role of CD133 molecule in WNT response and renal repair 23.74
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 23.62
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 23.61
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 23.15
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 23.1
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 22.99
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 22.99
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 22.7
RNA-seq analysis of control and Myc-induced U2OS cells 22.54
Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin 22.48
RNA-seq of MDA-MB-231 cells with TET1 knockout 22.47
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 22.4
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 22.38
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 22.38
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 22.34
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 22.1
Redifferentiation of expanded human islet β cells by inhibition of ARX 21.57
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 21.55
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 21.39
RNA-sequencing of healthy human skeletal myocytes 21.33
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 21.22
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 21.14
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 20.86
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 20.86
A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells 20.6
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 20.57
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 20.57
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 20.55
Treatment of SW480 colon cancer cell induced xenografts with AZD and DBZ 20.42
Control of prostate tumour growth by the long non-coding RNA GHSROS 20.23
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies 20.22
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq] 20.22
Gene expression alterations of pancreatic intraepithlial neoplasia 19.82
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells with PolyIC treatment 19.66
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 19.66
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 19.66
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 19.55
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 19.47
High level DNA repair gene expression in human ES cells 19.4
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 19.35
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 19.33
RNA-seq melanoma 19.1
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 19.06
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 19.06
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 18.16
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 18.16
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 17.62
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 17.42
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 17.39
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 17.33
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 17.27
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 16.91
16.9
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq] 16.79
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes 16.79
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 16.69
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 16.61
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 16.61
Transcriptional responses of melanoma cells to BRAF inhibition 16.57
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 16.55
Gene expression profile in breast cancer cells 16.53
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 16.53
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 16.2
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 16.2
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 16.16
The role of CFTR in islet function 16.0
Proteomics identifies a marker signature of MAPKi resistance in melanoma 15.96
High-efficiency RNA-based reprogramming of human primary fibroblasts 15.88
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 15.7
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 15.67
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 15.67
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 15.66
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 15.59
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells 15.56
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq) 15.56
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 15.32
Gene expression profile difference among renal location in a stone former 15.19
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 15.09
Total RNA sequencing of WT intestinal orgaonids. 15.0
CHD1 regulates cell fate determination by activation of differentiation-induced genes 14.88
GATA3-mediated chromatin reprogramming in breast cancer cells 14.65
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 14.54
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 14.54
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 14.54
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 14.52
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 14.52
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 14.51
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 14.51
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 14.5
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 14.5
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 14.36
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 14.36
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 14.28
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 14.28
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 14.27
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 14.08
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 13.95
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 13.95
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 13.87
Overexpression and knockdown experiment for circCSNK1G3 13.81
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 13.7
Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression 13.64
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq] 13.61
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma 13.61
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 13.56
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 13.56
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 13.56
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 13.49
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 13.46
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 13.29
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 13.06
HNF1A deficiency impairs β-cell fate, granule maturation and function 12.97
Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1 12.93
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 12.75
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 12.74
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 12.68
Unraveling cis-regulatory elements by mapping structural changes in mRNAs 12.66
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 12.59
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 12.54
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 12.4
OBESITY IS ASSOCIATED WITH IMPAIRED EXPRESSION OF THE GLYCOSYLTRANSFERASE EOGT IN DECIDUALIZING ENDOMETRIUM 12.29
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 12.18
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 12.18
RNA-seq of shEZH2 cells 12.13
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia 12.1
p53 activity results in DNA replication fork processivity 11.99
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 11.88
Regulation of hypoxia-inducible factor activity by ZMYND8 11.86
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 11.7
mRNA expression data from ESCs derived by polar body transfer reconstructed embryos (PBTESCs) 11.64
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 11.63
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 11.48
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 11.48
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 11.48
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 11.47
Random mono-allelic expression in MECP2-mutated cells 11.47
Next Generation Sequencing of human SMA and healthy control Motor Neurons 11.43
Genome-wide expression analysis of young, senescent and p38MAPK-inhibitited senescent human fibroblasts. 11.33
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 11.26
mRNA sequencing of oropharyngeal cancer cell lines 11.26
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 11.24
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 11.2
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 11.07
RNA-seq of cells with TET1 knockout 11.06
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 11.02
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 10.92
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 10.91
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 10.91
hTERT promotes cell adhesion and migration independent of telomerase activity 10.85
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 10.61
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 10.61
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 10.57
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 10.42
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 10.41
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 10.34
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 10.06
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 9.99
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 9.95
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 9.88
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 9.84
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 9.74
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 9.6
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 9.6
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 9.6
Mutational landscape of splicing genes and functional consequences across 33 cancer types 9.5
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 9.17
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 9.16
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 9.14
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 8.99
RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d) 8.99
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 8.98
Transcriptome analysis of human lung epithelial cells 8.93
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 8.92
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 8.92
EGR1-controlled transcriptome of T HESCs 8.9
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 8.89
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 8.88
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 8.86
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 8.74
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 8.71
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 8.71
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 8.69
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 8.58
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 8.58
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 8.57
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 8.56
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 8.47
Analyses of a panel of transcripts and construction of RNA networks in hepatocellular carcinoma 8.33
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 8.18
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 8.09
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 8.09
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 7.93
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 7.9
RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq] 7.83
Evolving Spindlin1 Small Molecule Inhibitors Using Protein Microarrays 7.83
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 7.81
Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression 7.78
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 7.74
Transcriptome analysis of eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyps reveals distinct lncRNA expression profiles 7.71
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 7.71
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 7.68
Next Generation Sequencing Facilitates Quantitative Analysis of ALDH+ E-BCSC, CD24-CD44+ M-BCSC and Bulk tumor cell Transcriptomes from MC1 and Vari068 PDX models of TNBC 7.61
Identification of a LIF-responsive replication-competent human β cell 7.52
mRNA Sequencing of Human PromoCells Using Random Primed mRNA-Sequencing Technique 7.49
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 7.35
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 7.32
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 7.21
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 7.21
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 7.18
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 7.08
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 7.05
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 7.05
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 7.04
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 6.97
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 6.92
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 6.88
Subcellular pathways shared by afflicted patients and mutant mice identify a new drug treatment for aortic aneurysm in Marfan syndrome 6.88
PGE2 mediated gene expression changes in human cervical stromal cells 6.85
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 6.84
Ribosome profiling upon inhibition of eIF4A 6.84
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 6.8
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 6.75
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 6.66
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 6.63
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 6.51
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 6.5
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 6.5
Neurofibroma 6.45
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 6.45
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 6.41
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 6.41
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 6.26
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 6.26
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 6.2
Small-molecule targeting of brachyury transcription factor addiction in chordoma 6.12
Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver [RNA-Seq] 6.03
Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver 6.03
The DNA methylation landscape of human melanoma [RNA-Seq] 6.03
The DNA methylation landscape of human melanoma 6.03
An acquired vulnerability of drug resistant melanoma with therapeutic potential 5.99
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 5.99
Organoids derived from directly reprogrammed human hepatocytes for modeling liver cancer initiation 5.94
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 5.93
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 5.88
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 5.88
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 5.8
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 5.8
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 5.8
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 5.77
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 5.76
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 5.75
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 5.61
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 5.59
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 5.53
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 5.51
Persistence of stem cell metabolism in cancers as a failure of differentiation 5.45
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 5.34
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 5.34
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 5.32
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 5.27
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 5.2
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines 4.99
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines (mRNA-Seq) 4.99
RNA sequencing of human pancreatic cancer cell lines 4.98
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 4.81
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 4.81
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 4.77
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 4.77
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 4.71
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 4.7
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 4.65
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 4.58
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 4.58
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 4.49
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 4.32
mRNA differential expression analysis in a human ex vivo model of chronic wounds 4.3
Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells 4.23
RNA-seq analysis upon ARID1B overexpression 4.11
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 4.1
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 3.82
Transcriptome profiling of CXCR2+ neuroendocrine (NE) tumor cells purified from patients' fresh prostate adenocarcinoma 3.81
mRNA sequencing analysis of cultured human primary airway epithelial cells upon exposure to PMN exosomes 3.77
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma 3.75
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 3.74
The effect of Abl kinases on non-small cell carcinoma global transcriptome 3.69
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 3.5
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 3.44
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 3.32
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 3.23
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 3.21
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 3.17
A Basal Stem Cell Signature Identifies Aggressive Prostate Cancer Phenotypes 3.17
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 3.15
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 3.14
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 3.14
Modeling Familial Cancer with iPSC Approaches 3.12
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 3.07
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 3.04
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 3.03
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 3.02
Paclitaxel plus Cirmtuzumab Achieves Greater Clearance of Patient-derived Xenografts By Targeting ROR1+ Breast Cancer Stem Cells 2.97
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 2.89
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 2.89
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 2.81
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 2.81
Generation of Patient-Matched Malignant and Normal Primary Cell Cultures from Clear Cell Renal Cell Carcinoma Patients 2.79
Profiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis 2.77
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 2.75
RNA Seq of Alagille liver biopsies 2.72
Alagille_Nodder 2.72
DECIDUALIZATION INDUCES A SECRETOME SWITCH IN THE PERIVASCULAR NICHE CELLS OF THE HUMAN ENDOMETRIUM 2.66
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 2.59
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 2.57
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 2.51
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 2.49
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 2.49
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 2.39
Activating Transcription Factor 4 modulated TGFb-induced aggresiveness in triple negative breast cancer vis SMAD2/3/4 and mTORC2 signaling 2.32
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 2.23
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 2.23
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 2.23
Leucegene: ALL sequencing 2.22
Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma 2.16
Global hypomethylation mediated changes regulate constitutive PD-L1 expression in melanoma [RNA-Seq] 2.16
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 2.16
Leucegene: AML sequencing (part 6) 2.13
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 2.06
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 2.0
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 2.0
Patient-derived xenograft platform for metastatic melanoma: a model for studying resistance to targeted therapy. 1.99
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 1.94
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 1.94
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 1.85
Short and long-term effects of CDK4/6 inhibition on early stage breast cancer 1.82
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 1.82
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 1.8
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 1.8
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 1.78
CDK12 mediated transcriptional regulation in U2OS cells 1.77
Hepatic transcriptome of pediatric hepatoblastoma. 1.74
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 1.69
Efficient derivation of microglia-like cells from human pluripotent stem cells 1.57
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 1.52
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 1.49
RNA seq comparison between scrambled and shGRP78 cells 1.43
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC 1.26
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC [Total RNA-Seq] 1.26
Gene expression profiling of human and murine in vitro muscle differentiation 1.25
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 1.17
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 1.15
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 1.15
Patient-derived xenograft platform for metastatic melanoma 1.14
Human islets of varying quality: the good, the (not so) bad and the ugly 1.13
Transposon-based construction of strand-specific RNA-seq libraries 1.11
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 1.02
RNA-Seq of Breast and Ovarian Cancer Cell Lines 0.96
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 0.87
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.86
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 0.84
Identification of differentially expressed genes between senescence and senescence bypass cells 0.78
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 0.77
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 0.72
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 0.72
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 0.72
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.69
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 0.69
Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines. 0.68
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 0.66
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 0.62
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 0.61
Expression profiling of converted and control dermal BJ fibroblasts 0.53
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 0.53
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.46
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.46
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 0.42
Gene Expression Profile of human hepatocellular carcinoma by RNA sequencing 0.39
BET bromodomain inhibition 0.36
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 0.36
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.35
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 0.33
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 0.33
Gene expression of thyroid cancer cell lines 0.3
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas 0.27
Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products 0.13
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 0.13
BMS-470539 on human synovial fibroblasts 0.12
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.08
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 0.06


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