Gene Query: LRCH2

Dataset Description Geneva Score
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 21.65
Transcriptomic of MKD (MUC1 kidney disease) patient compares to normal derived kidney epithelial cells 18.38
Transcriptional responses of human insulinoma cells to acute cytokine exposure 16.46
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 16.26
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 16.26
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 13.53
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 13.02
Transcriptome analysis of H9 hESC derived cerebral organoids 12.46
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 12.15
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 11.19
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 11.15
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 10.95
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 10.58
Proteolytic cleavage by taspase1 and the regulation of the stability of MLL1 10.56
RNA-seq in transgenic cells 10.33
Examining serotonergic neuron differentiation from human iPSCs 9.84
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 9.53
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 9.15
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 8.7
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 8.68
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 8.55
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 8.31
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 8.26
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 7.87
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 7.87
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 7.75
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 7.71
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 7.62
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 7.43
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 7.39
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 7.39
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 7.03
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 6.99
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 6.98
Global Mapping of Human RNA-RNA Interactions 6.86
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 6.79
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 6.76
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 6.45
The contribution of Alu exons to the human proteome 6.42
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 6.3
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 6.18
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 6.03
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 6.03
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 5.88
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 5.76
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 5.75
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 5.73
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 5.7
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 5.7
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 5.68
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 5.65
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 5.61
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 5.57
RNA sequencing of BT142 and TS603 cell lines 5.57
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 5.48
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 5.34
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 5.34
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 5.32
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain 5.19
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 5.1
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 5.02
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 5.02
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 5.0
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 4.9
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 4.77
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 4.74
Single-cell analysis of human kidney organoids 4.64
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 4.62
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 4.58
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 4.58
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 4.52
Expression profiling of etoposide-induced senescent cells 4.49
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 4.45
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 4.42
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 4.38
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 4.34
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 4.33
Gene expression profiles of ibrutinib-responsive and ibrutinib non-responsive cells in ERBB4 expressing cancer cell lines 4.27
iPSC derived motor neuron cultures from C9ORF72 carriers 4.23
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 4.17
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 4.16
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 4.12
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 4.08
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 3.99
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 3.98
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 3.96
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 3.89
Obstructed defecation – an enteric neuropathy? An exploratory study of patient samples 3.86
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 3.82
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 3.82
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 3.71
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 3.69
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 3.68
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 3.67
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 3.66
A transcriptome-wide divergence in protein translation scales with LIN28B expression 3.58
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 3.52
RNA-Seq analysis of neurons derived from induced pluripotent stem cells reprogrammed from dental pulp 3.52
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 3.52
Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli 3.5
Expression profiles of the four human major ectodermal lineages 3.5
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 3.46
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 3.45
FGF2 regulation of gene expression in stable inducible Neurons 3.45
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 3.4
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 3.38
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 3.38
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 3.37
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 3.36
NHLRC1 re-expression in cancer cells 3.33
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 3.28
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 3.28
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 3.28
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 3.28
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 3.26
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 3.24
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 3.22
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 3.2
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 3.2
Tracking distinct RNA populations using efficient and reversible covalent chemistry 3.16
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 3.16
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 3.16
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 3.16
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 3.15
Genome-wide analysis of herpes simplex virus type 1 (HSV-1) infected cells 3.11
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 3.09
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 3.09
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 3.08
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche 3.07
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 3.05
The cohesin release factor WAPL restricts chromatin loop extension. 3.05
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 3.05
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 3.03
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 3.03
Engineering Patient-Specific Tissue Implants 3.02
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 3.01
Total RNA sequencing of APC mutant and wt colonic organoids 3.0
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 3.0
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 2.99
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 2.96
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 2.91
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 2.89
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 2.86
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 2.84
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 2.84
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 2.84
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 2.79
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 2.79
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 2.76
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 2.76
AUF-1 affected genes in human skin cells 2.76
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 2.76
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 2.74
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 2.69
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 2.68
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 2.64
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 2.63
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 2.6
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 2.59
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 2.59
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 2.52
SRSF1 role in cellular gene expression and splicing 2.52
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 2.51
Gene expression profile of human iPSC-derived nephron progenitor cells 2.5
Evolution of a transcriptional regulator from a transmembrane nucleoporin 2.49
RNA-seq in HepG2 and IMR90 cells 2.49
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 2.47
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 2.42
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 2.41
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 2.41
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 2.39
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 2.39
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 2.38
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 2.33
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 2.32
PGE2 mediated gene expression changes in human cervical stromal cells 2.31
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 2.31
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 2.31
RNA-seq of shEZH2 cells 2.31
Modeling Trilateral Retinoblastoma using Human Embryonic Stem Cells 2.3
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 2.28
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 2.28
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 2.27
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 2.27
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 2.26
Mapping interactions for the TNIP2 hub protein 2.21
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 2.19
Human cell line and subcutaneous tumor 2.18
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 2.17
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 2.17
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 2.15
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 2.14
Transcriptome of U251 cells overexpression complement component 7 2.13
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 2.12
iPSC-Derived Cholangiocytes 2.11
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 2.1
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 2.1
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 2.09
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 2.08
Identification of a LIF-responsive replication-competent human β cell 2.07
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 2.07
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 2.06
HEK293 Heat-shock experiment 2.06
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 2.04
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 2.01
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 1.99
LINE-2 transposable elements are a source of functional human microRNAs and target sites 1.99
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 1.99
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 1.99
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 1.98
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 1.97
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 1.97
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 1.97
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 1.94
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 1.92
FOXP2's impact on the primate transcriptome 1.86
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 1.84
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 1.84
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 1.83
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 1.82
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 1.82
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 1.82
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 1.81
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 1.81
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 1.81
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 1.8
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 1.79
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 1.78
Effect of Hotair overexpression in human breast cancer cell lines 1.78
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 1.76
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 1.76
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 1.75
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 1.74
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 1.71
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 1.7
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 1.7
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 1.7
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 1.68
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 1.68
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 1.65
Gene induction by the USP6 oncogene in response to interferon 1.65
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 1.65
Endothelial gene expression analysis 1.65
Derivation of ventrical and atrial cardiomyocytes and maturation using biowires 1.64
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 1.64
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 1.63
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 1.63
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 1.61
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 1.6
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 1.59
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 1.59
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 1.58
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 1.58
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 1.56
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 1.55
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 1.54
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 1.53
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 1.53
Epigenome regulation during epidermal lineage commitment 1.53
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 1.52
Effect of disulfiram treatment on pediatric high grade glioma 1.52
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 1.52
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 1.51
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 1.51
Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq] 1.48
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 1.47
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 1.47
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 1.46
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 1.46
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 1.46
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 1.46
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 1.46
Next Generation Sequencing of human SMA and healthy control Motor Neurons 1.45
hESC neural differentiation 1.45
RNA-seq analysis of gene expression patterns during hESC neural differentiation 1.45
Global transcriptome analysis of HAP1 cells 1.45
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 1.44
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 1.44
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 1.44
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 1.43
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 1.43
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 1.41
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 1.41
Dissecting neural differentiation regulatory networks through epigenetic footprinting 1.41
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 1.41
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 1.41
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 1.41
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 1.41
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 1.4
Cleavage Factor Im as a key regulator of 3’ UTR length 1.39
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 1.38
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 1.38
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 1.37
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 1.37
The MEF2B Regulatory Network 1.37
The MEF2B Regulatory Network - RNA-seq data 1.37
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 1.36
STX4 Over-Expression in Human islets 1.35
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 1.34
Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine 1.34
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 1.34
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 1.34
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 1.33
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs 1.33
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs (expression) 1.33
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 1.32
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 1.32
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 1.32
Cerebellar differentiation in Ataxia-Telangiectasia 1.31
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 1.31
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 1.29
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 1.29
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 1.29
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 1.27
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 1.27
Spliceosomal disruption of the non-canonical BAF complex in cancer 1.26
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 1.25
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 1.24
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 1.23
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 1.23
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 1.22
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 1.22
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 1.22
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 1.21
Gene expression analysis upon mtDNA depletion 1.2
Gene expression analysis upon mtDNA depletion [RNA-seq] 1.2
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 1.2
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 1.2
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 1.19
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 1.19
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 1.17
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 1.17
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 1.17
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 1.17
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 1.17
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 1.17
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 1.16
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 1.16
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 1.15
IL-33 activates tumor stroma to promote intestinal polyposis 1.15
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 1.15
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 1.15
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 1.15
Gene expression profiling of human iPS cell-derived podocytes and sorted human adult podocytes 1.14
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 1.1
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 1.1
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 1.1
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.08
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 1.07
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 1.07
Determination of tRNA aminoacylation levels by high throughput sequencing 1.07
Biological effect of chronic mistranslation in mammalian cells 1.06
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 1.06
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 1.06
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 1.06
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 1.04
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 1.04
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 1.02
AMPK signaling for naïve pluripotency 1.02
AMPK signaling for naïve pluripotency [Hs] 1.02
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 1.02
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 1.01
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.01
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 0.99
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 0.98
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 0.93
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 0.93
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 0.91
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 0.91
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 0.9
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 0.9
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.89
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.89
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 0.88
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 0.87
Transcriptome analysis of kidney organoids 0.86
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 0.85
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 0.85
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 0.83
MYCL and EP400 are required for Max and MCPyV mediated gene activation 0.82
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 0.82
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 0.81
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.8
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.8
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 0.79
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 0.76
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 0.76
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 0.75
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.75
RNA-seq analysis upon ARID1B overexpression 0.74
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 0.73
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 0.73
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 0.72
Transcriptome of EBV-infected gastric cancer cell lines 0.69
Identification of differentially expressed circRNA in gallbladder cancer compared with matched normal tissue 0.68
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.68
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 0.67
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 0.66
HEK293 TFAM Knockout Expression Study 0.66
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 0.65
Controlling for gene expression changes in transcription factor protein networks. 0.65
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 0.64
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 0.64
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 0.63
Histone Demethylases KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging through condensin-mediated heterochromatin organization 0.61
Zika virus directly infects human peripheral neurons and induces cell death 0.61
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.61
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.61
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 0.58
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 0.56
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 0.56
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 0.56
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 0.56
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 0.55
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 0.55
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 0.54
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.54
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 0.54
Age-Related Gene Expression Changes in Prostate Cancer Patients [RNA-Seq] 0.53
Age-Related Gene Expression Changes in Prostate Cancer Patients 0.53
Zika virus infection reprograms global transcription of host cells to allow sustained infection 0.53
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.53
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 0.52
The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactions 0.52
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 0.51
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 0.5
Human HAP1 cells before and after nutrient deprivation 0.5
O-glcnAc reprograms cellular energetics 0.49
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 0.49
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 0.48
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 0.48
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 0.48
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 0.47
Expression charcaterization of an internal protocol developed to differentiate RPE cells 0.46
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 0.44
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  0.43
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 0.42
Derivation and differentiation of haploid human embryonic stem cells 0.4
Lysine benzoylation is a novel histone mark 0.4
Lysine benzoylation is a novel histone mark [RNA-seq] 0.4
Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle 0.38
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 0.37
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 0.36
miR941 overexpression experiment 0.35
Derivation and differentiation of haploid human embryonic stem cells [RNA-Seq 1] 0.34
Transcriptome analysis upon C6orf203 silencing 0.34
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 0.33
RNA-Seq in PWS iPSC-derived neurons 0.32
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.3
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 0.29
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 0.29
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.29
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 0.26
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 0.24
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.24
Human ovarian granulosa cell transcriptome 0.24
Primate-specific gene TMEM14B promotes cortical expansion and folding 0.22
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 0.2
Transcriptome analysis of diverse cell types infected with human cytomegalovirus 0.2
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 0.2
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 0.19
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 0.19
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.18
FOXP1 orchestration of ASD-relevant signaling pathways. 0.17
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 0.17
Role of FGFR1 in neuronal devlopment 0.17
Ribosomal protein RPL26 is the principal target of UFMylation 0.17
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 0.17
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 0.16
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 0.15
eRNA: A graphic user interface-based tool for RNA sequencing data analysis 0.15
eRNA: A graphic user interface-based tool for RNA sequencing data analysis [mRNA-Seq] 0.15
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 0.15
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 0.15
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 0.14
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.13
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 0.13
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 0.13
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 0.12
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 0.12
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 0.12
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.11
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 0.11
RNA splicing alteration on glioblastoma and normal neural stem cells 0.11
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 0.1
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.1
Modulation of nonsense-mediated decay by rapamycin 0.08
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 0.07
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.07
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 0.07
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 0.07
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 0.06
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 0.06
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 0.05
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 0.05
Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin 0.05
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 0.04
Anti-Inflammatory Effects of Budesonide in Human Fetal Lung 0.03
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.01
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 0.0


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