Gene Query: LRP8

Dataset Description Geneva Score
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 68.21
Nrf2 regulated genes in A549 cells 60.78
Identification of Nrf2 regulated genes by RNA sequencing 60.78
Gene expression analysis of the impact of TDP-43 knockout in human cells. 52.82
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 52.22
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 48.56
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 45.38
WRN knockout effects upon gene expression in SW48 and OVK18 40.41
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 39.31
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 38.58
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 38.58
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with Eralpha 37.76
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 37.73
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 37.71
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 36.45
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 36.01
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 35.84
RNAseq analysis of ESRP regulated splicing events in prostate cancer 35.17
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 34.79
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 34.33
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 34.33
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 33.35
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 33.35
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 32.98
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 32.98
Control of prostate tumour growth by the long non-coding RNA GHSROS 32.36
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 30.84
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 30.1
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 29.61
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 29.6
Transcriptome analysis in Neobractatin treated cells 28.97
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 28.91
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 28.72
RNA-seq analyisis of PUM2 knockout cells 28.72
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 28.46
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 28.46
FOXD3 is a novel tumor suppressor in lung cancer 28.23
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 27.97
Ectoderm specification of H1 human embryonic stem cells 27.24
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 26.95
Rorc disruption in human FG pancreatic cancer cells 26.69
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 26.27
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 26.26
Genetic-to-epigenetic Therapy for Pancreatic Cancer 26.04
Overexpression of NFIB and YBX1 in MCF-7 cells 25.55
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 25.23
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 25.1
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 24.92
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 24.9
Toxoplasma gondii infection of human retinal pigment epithelial cells 24.75
Irf9 function in immunity in mouse 24.42
Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons 24.42
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 24.19
6mer seed toxicity in tumour suppressive microRNAs 23.94
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 23.85
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 23.85
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 23.79
LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines 23.77
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 23.45
Regionally specified human pluripotent stem cell-derived astrocytes 23.18
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 23.14
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 23.0
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 22.5
NR2F2 study 22.49
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 22.49
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 22.45
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 22.41
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 22.06
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 22.03
Regulating Interleukin-2 activity with engineered receptor signaling clamps 21.99
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 21.9
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 21.85
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 21.7
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 21.69
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 21.65
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 21.12
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 21.04
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 21.02
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 20.68
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 20.61
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 20.41
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 20.41
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 20.23
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 20.23
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 20.18
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 20.15
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 20.06
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 20.06
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 19.87
RNA-seq of YB5 cells treated with Proscillaridin A 19.86
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche 19.83
MeRIP-seq for heat shock in B-cell lymphoma cells 19.76
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 19.71
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 19.55
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 19.55
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 19.5
Paxillin regulates genomic networks in prostate cancer [LNCaP] 19.48
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 19.42
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 19.4
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 19.37
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 19.29
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 19.21
Genome wide expression change by RNF168 knocking down in MCF-7 cells 18.92
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 18.83
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 18.74
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 18.51
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 18.48
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 18.36
Transcriptome analysis of BAP1 knockout and restoration 18.21
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 18.21
Uridylation by TUT4 and TUT7 marks mRNA for degradation 18.2
Uridylation by TUT4 and TUT7 marks mRNA for degradation [RNA-Seq] 18.05
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 17.97
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 17.89
Epigenomic landscape during organ formation in human early embryos 17.84
Dynamic reorganization of nuclear architecture during human cardiogenesis [RNA-seq] 17.62
Dynamic reorganization of nuclear architecture during human cardiogenesis 17.62
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2) 17.6
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 17.27
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 17.22
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 17.14
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 16.92
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 16.86
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 16.75
Grainyhead-like 2 (GRHL2) and epigenetic remodeling in the intermediate states of epithelial-mesenchymal transition 16.68
Grainyhead-like 2 (GRHL2) and epigenetic remodeling in the intermediate states of epithelial-mesenchymal transition [RNA-seq] 16.68
Total RNA-seq in ALL-SIL upon JQ1 inhibition 16.65
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 16.6
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 16.5
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 16.49
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 16.45
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 16.2
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 16.19
PTHrP overexpression in MCF7 cells 16.19
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 16.13
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 16.06
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 16.06
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 15.99
RNA-seq melanoma 15.96
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 15.75
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 15.56
Treatment of SW480 colon cancer cell induced xenografts with AZD and DBZ 15.4
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 15.39
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 15.33
Genome-wide analysis of herpes simplex virus type 1 (HSV-1) infected cells 15.25
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 15.23
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 15.23
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 15.2
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 15.18
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 15.18
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 15.18
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 15.17
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 15.06
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 15.05
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 15.01
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 14.88
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 14.88
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 14.88
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 14.87
Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation 14.84
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 14.79
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 14.74
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 14.71
LIN28A modulates splicing and gene expression programs in breast cancer cells 14.67
LIN28A modulates splicing and gene expression programs in breast cancer cells [RNA-Seq] 14.67
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 14.66
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 14.58
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 14.58
Silencing p300 in MCF7 cells to study expression and alternative splicing 14.58
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 14.56
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 14.55
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 14.52
SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis 14.52
High-Throughput Kinetic Analysis of Fractional Killing 14.37
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 14.33
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 14.32
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 14.21
FOXP1 orchestration of ASD-relevant signaling pathways. 14.13
A role for ZNF598 in post-transcriptional gene regulation 14.06
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 14.01
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 14.01
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 13.96
Downregulation of DDX5/DDX17 and REST 13.94
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 13.94
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 13.94
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 13.74
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 13.74
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 13.73
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 13.68
The regulartory role of ZCCHC24 in splicing machinery 13.67
Gene expression profiling of leukemia cells following asparagine depletion 13.63
Human ovarian granulosa cell transcriptome 13.59
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 13.59
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 13.49
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 13.13
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 13.09
SNHG5 siRNA knock down in HCT116 cells 13.0
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 12.98
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 12.98
Effect of Influenza virus infection on lncRNA expression in A549 cells 12.9
IL-33 activates tumor stroma to promote intestinal polyposis 12.85
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 12.79
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 12.77
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  12.7
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 12.65
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 12.61
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 12.5
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 12.46
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 12.46
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  12.42
PNET animal model: new insights (II) 12.39
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 12.33
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 12.27
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 12.27
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 12.21
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells [RNA-seq] 12.14
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells 12.14
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 12.12
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 12.09
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 12.08
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 12.08
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 12.04
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 11.99
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 11.97
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 11.91
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 11.89
RNA-seq differential expression studies: more sequence, or more replication? 11.88
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 11.81
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 11.81
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 11.81
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 11.81
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 11.8
Induced DNA demethylation, genome instability and transcription 11.8
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 11.78
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 11.72
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 11.68
Peptidomimetic blockade of MYB in acute myeloid leukemia 11.68
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 11.67
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 11.66
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 11.66
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 11.51
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 11.51
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 11.51
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 11.47
BET bromodomain inhibition 11.43
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 11.43
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 11.37
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 11.34
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 11.31
TGF-β promotes genomic instability after loss of RUNX3 11.26
BI Human Reference Epigenome Mapping Project 11.23
Gene expression analysis of dengue-infected cells 11.11
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 11.08
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 11.08
Entrectinib Resistance in a Neuroblastoma Xenograft Model 10.99
Effect of from Human Umbilical Vein Endothelial Cells 10.98
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 10.95
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 10.88
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 10.88
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 10.87
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 10.86
High-efficiency RNA-based reprogramming of human primary fibroblasts 10.84
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 10.84
Exploring ILF2 regulatory genes by next-generation sequencing 10.84
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 10.83
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 10.81
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 10.78
Integrin signaling regulates YAP/TAZ to control skin homeostasis 10.78
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 10.72
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 10.71
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 10.71
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 10.62
A549 cells and MSR-A549 cells 10.62
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 10.61
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 10.61
RNA-seq of human fibroblasts after irradiation 10.61
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 10.56
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 10.56
The MEF2B Regulatory Network - RNA-seq data 10.48
The MEF2B Regulatory Network 10.48
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 10.47
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 10.47
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 10.4
Global gene expression profile of dasatinib-resistant RCH-ACV cells 10.39
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 10.38
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 10.33
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 10.26
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 10.25
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 10.22
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 10.2
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 10.2
U1 snRNP telescripting regulates size-function stratified human genome 10.13
RNA expression analysis upon JMJD1C depletion 10.05
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 10.05
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 10.04
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 10.03
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion 10.02
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 9.97
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 9.95
Expression charcaterization of an internal protocol developed to differentiate RPE cells 9.94
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 9.92
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 9.83
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 9.83
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 9.77
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 9.77
Effect of Hotair overexpression in human breast cancer cell lines 9.76
A transcriptome-wide divergence in protein translation scales with LIN28B expression 9.72
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 9.68
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 9.63
An acquired vulnerability of drug resistant melanoma with therapeutic potential 9.63
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 9.63
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 9.62
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 9.55
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 9.44
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 9.41
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 9.37
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 9.36
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 9.36
RNA-seq analysis of RALD iPSCs after in vitro differentiation 9.33
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 9.31
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 9.3
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 9.3
MYCL and EP400 are required for Max and MCPyV mediated gene activation 9.23
MEIS1 regulates hematopoiesis in hPSCs 9.18
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 9.17
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 9.17
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 9.14
Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle 9.07
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 8.8
IRF1 regulates IFN dependent and independent gene expression 8.75
Energy Metabolism during Anchorage-Independence 8.7
RNA-seq of naive and primed ES cells 8.64
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 8.62
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 8.61
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 8.57
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 8.52
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 8.5
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 8.42
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 8.42
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 8.38
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 8.32
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 8.23
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 8.17
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 8.11
Identification of long noncoding RNAs regulated by p53 8.1
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 8.09
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 8.06
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 8.06
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 8.06
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 8.06
KSDM1b Role in Ewing Sarcoma 8.03
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 8.0
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 8.0
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 7.96
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 7.94
Co-regulation of splicing by Rbfox1 and hnRNP M 7.94
hnRNP C is a key regulator of protein synthesis in mitosis 7.9
SLIGRL-induced gene expression changes in NHEK cells 7.88
Subtle asymmetry of gene expression in embryonic and foetal human brains 7.8
MCF-7 as a model for functional analysis of breast cancer risk variants 7.74
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 7.7
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 7.7
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 7.64
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 7.59
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 7.58
Hijacking of stress response machinery by oncogenes in acute leukaemia 7.58
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 7.52
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 7.52
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 7.49
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 7.43
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 7.43
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 7.42
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 7.42
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 7.4
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 7.4
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 7.34
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 7.29
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 7.26
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction 7.25
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 7.21
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 7.21
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 7.18
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 7.15
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 7.02
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 6.85
iPSC-Derived Cholangiocytes 6.77
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 6.63
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 6.46
IMP3 regulated gene expression in breast cancer cells 6.42
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 6.29
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 6.28
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 6.24
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 6.23
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 6.07
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 5.65
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 5.53
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 5.41
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 5.38
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 5.34
Novel kinase fusion oncogenes in post-Chernobyl radiation-induced pediatric thyroid cancers 5.29
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 5.22
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 5.17
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 5.17
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 5.14
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 5.05
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 5.04
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 5.04
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 4.91
Expression profiles of the four human major ectodermal lineages 4.89
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 4.86
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 4.76
RNA seq analysis of human Fetal and adult derived Enterospheres 4.76
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 4.75
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 4.74
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 4.7
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 4.7
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 4.68
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 4.68
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 4.68
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 4.67
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 4.67
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 4.52
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 4.35
Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells 4.35
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 4.26
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 4.19
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 4.18
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 4.1
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 4.04
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 3.96
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 3.95
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 3.78
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 3.66
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 3.6
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) 3.55
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) [RNA-seq] 3.55
RNA seq_PDX2_SHP099 3.43
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 3.42
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 3.4
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 3.35
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 3.23
Targeted enhancer activation by a subunit of the integrator complex 3.21
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 3.12
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 3.12
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 3.07
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 3.07
CD73 knockdown effect in pancreatic cancer cell lines 3.05
Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling 3.0
A20 regulates canonical wnt-signaling through an interaction with RIPK4 2.97
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 2.96
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 2.93
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 2.75
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 2.75
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 2.74
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 2.61
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 2.56
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 2.45
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 2.42
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 2.4
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 2.4
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 2.36
RNA-Seq of the corpus callosum from 12 individuals 2.35
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 2.34
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 2.3
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 2.25
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 2.21
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 2.21
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 2.15
Estrogen Receptor Beta Impacts Hormone-Induced Alternative mRNA Splicing in Breast Cancer Cells 2.11
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 2.01
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 1.97
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 1.82
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 1.67
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 1.51
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 1.51
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 1.44
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 1.4
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 1.36
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 1.26
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 1.2
Gene expression analysis in response to hypoxic pathway inhibition 1.15
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 1.13
N6-methyladenine DNA Modification in Glioblastoma 0.87
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 0.87
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 0.86
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 0.63
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 0.55
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 0.47
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 0.44
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.43
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 0.36
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.31
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.29
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 0.25
Finding missing proteins from epigenetically manipulated human cells 0.2
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.18
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.14
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.14
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 0.1
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 0.08


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