Gene Query: LYL1

Dataset Description Geneva Score
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 47.09
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 42.88
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 42.88
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 39.35
Novel Non-catalytic Substrate-selective p38α-specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-inflammatory Activity 38.25
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 34.11
Spliceosomal disruption of the non-canonical BAF complex in cancer 28.23
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 27.67
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 27.07
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 27.07
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing 26.52
Multiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing [RNA-seq] 26.52
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 26.03
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 23.69
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 23.58
Gene expression changes associated with resistance to tagraxofusp (SL-401) 22.61
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 21.97
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 21.42
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 21.14
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 21.0
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 19.03
RNA sequencing of hPSC-derived cardiac progenitors and endocardium 18.2
MEIS1 regulates hematopoiesis in hPSCs 16.74
Tpl-2 and MEK small molecule inhibitors 16.69
Tpl-2 small molecule project 16.69
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 16.62
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 16.62
Epigenomic landscape during organ formation in human early embryos 15.31
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 15.3
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 15.3
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 14.93
Global analysis of enhancer targets: Mosaic-seq 14.78
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 14.6
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 14.56
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes 14.45
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 14.41
Accurate annotation of human protein-coding small open reading frames 14.14
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 13.83
Global gene expression differences between blood- and lymphatic-specific endothelial colony forming cells 13.21
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 12.39
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 12.31
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 11.96
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 11.95
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 11.87
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 11.78
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 11.74
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 11.54
A single cell reference map for human blood and tissue T cell activation 11.2
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 10.89
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 10.79
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 10.75
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 10.75
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 10.58
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 10.37
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 10.35
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 10.21
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 10.09
Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells 9.84
The Human Testis Cell Atlas via Single-cell RNA-seq 9.79
SLAM-seq for K562 endogenous mRNA decay 9.72
BACH2 in human plasma cell fate decision 9.66
Landscape of human mast cell chromatin: a rich resource for identification of novel mediators and genetic drivers of allergic and inflammatory diseases 9.54
Transcriptomic profiling of human CD34+ derived mast cells [RNA-Seq] 9.54
Comparative Analysis of the Transcriptome of Latent Autoimmune Diabetes (LADA) Patients from Eastern China 9.41
Short and Long RNA sequencing of human mature erythrocytes 9.28
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 9.27
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq] 9.27
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia 9.27
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 9.21
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 9.19
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 9.09
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 9.09
The Human Testis Cell Atlas via Single-cell RNA-seq (Healthy men scRNA-seq data set) 9.08
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 8.72
Dynamic 3D chromosomal landscapes in acute leukemia 8.64
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 8.64
RNA-sequencing of bulk CD19+ Thymic B cells from young (3 month - 4 year) and old (42 - 61 years) humans 8.62
RNA-sequencing of bulk CD19+ Thymic B cells from mice and humans 8.62
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 8.33
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 8.24
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 8.24
RNA sequencing of primary human platelets and in vitro cell lines 8.22
Transcriptional profiles of normal human mature B cells 8.07
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 7.88
RNA-sequencing of human peripheral blood mononuclear cells (PB MNCs) and induced neural progenitor cells derived from PB MNCs 7.86
Primary Human B-cell Temporal Response to CD40L Stimulation 7.77
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene 7.71
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene (RNAseq) 7.71
Single-cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos 7.68
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 7.57
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 7.37
Solid phase chemistry to covalently and reversibly capture thiolated RNA 7.24
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 7.2
Molecular Biomarkers Screened by Next-generation RNA Sequencing for non-sentinel lymph node status predicting in breast cancer patients with metastatic sentinel lymph node 7.2
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 7.11
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 7.0
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 6.88
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 6.88
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 6.86
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 6.78
Be1 and Be2 B cells are transcriptionally distinct 6.76
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 6.65
The pause-initiation limit restricts transcription activation in human cells 6.59
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 6.53
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 6.53
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 6.53
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 6.51
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 6.45
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 6.37
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 6.29
Identification of long noncoding RNAs in T-ALL cell lines 6.22
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 6.11
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 5.96
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 5.9
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 5.89
RNAseq analysis of the human neutrophil transcriptome, with and without in vitro cytokine stimulation 5.86
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 5.79
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 5.79
Defective structural RNA processing in relapsing-remitting multiple sclerosis 5.68
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells via Transcription Factor Conversion of Hemogenic Endothelium 5.59
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 5.54
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 5.49
Transcriptomic profiling of human peripheral blood-derived mast cells 5.49
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 5.48
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 5.47
Statins modulate endothelial transcriptional profile by inhibiting EZH2 5.43
Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle by inducing capillary sprouting and decreasing vascular permeability via reduced eNOS activity 5.26
K562 polyA RNA-Seq 5.24
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 5.23
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 5.21
Molecular Mechanisms of Endothelial Hyperpermeability 5.17
RNA polymerase in pre-B-ALL cell lines 5.05
LIN28A Over-expression RNAseq 5.04
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 4.98
Developmental stage specific chromosome architecture in human erythroid cells 4.97
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 4.97
A Unique Epigenomic Landscape Defines Human Erythropoiesis 4.97
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 4.97
Intron retention induced by microsatellite expansions as a disease biomarker. 4.93
Non-coding regions are the main source of tumor-specific antigens [human] 4.92
Non-coding regions are the main source of tumor-specific antigens 4.92
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 4.9
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 4.88
The evolution of N6-methyladenosine in primates 4.86
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 4.85
Seletive inhibition of CDK9 in DLBCL cell lines 4.84
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 4.81
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 4.78
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 4.76
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 4.76
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 4.68
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 4.64
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 4.59
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 4.56
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 4.56
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 4.55
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 4.55
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 4.55
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 4.54
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 4.52
Impact of Escherichia coli K12 and O18 on human platelets: effects on platelet activation, spliced platelet RNAs and proteins 4.49
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 4.46
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 4.38
LncRNA expression profiling of ischemic stroke patients 4.37
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 4.37
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 4.37
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 4.35
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (mRNA-Seq) 4.24
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 4.23
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 4.23
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 4.23
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 4.21
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 4.2
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 4.18
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 4.15
Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient 4.15
Effect of PRDM11 depletion in U2932 cells 4.13
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing 4.09
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 4.09
Single-Cell Genotyping of Transcriptomes 4.09
RNA-seq of Single-Cell Genotyping of Transcriptomes 4.09
Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells 4.07
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 4.03
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 3.97
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 3.92
Genome-wide discovery of human splicing branchpoints [RNAse] 3.83
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 3.7
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 3.68
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 3.63
Transcriptome Profiling of Human Primary Monocytes 3.62
A map of gene expression in neutrophil-like cell lines 3.61
Targeted enhancer activation by a subunit of the integrator complex 3.6
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 3.6
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 3.59
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 3.57
A novel target of EZH1/2 for treatment of mantle cell lymphoma 3.57
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 3.55
MYCi975 regulates MYC target genes 3.53
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 3.5
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.49
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 3.46
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.46
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 3.45
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 3.44
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 3.44
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus 3.43
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 3.41
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 3.41
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 3.41
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 3.38
Proteolytic cleavage by taspase1 and the regulation of the stability of MLL1 3.34
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 3.31
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 3.28
Identification of renal resident macrophages across species 3.26
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 3.17
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 3.16
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 3.13
Human T-cell lymphoblastic lymphoma samples and control thymuses 3.13
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 3.07
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 3.06
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 3.06
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 2.97
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 2.97
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 2.94
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 2.89
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 2.87
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 2.86
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 2.79
Copper Regulation of HIF-1 Transcription Activity 2.79
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 2.79
In situ CAPTURE of chromatin interactions by biotinylated dCas9 2.77
RNA-seq transcriptonal profiling in human K562 cells with or without dCas9 and sgRNAs 2.77
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 2.77
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 2.76
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 2.76
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 2.76
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 2.75
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 2.7
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 2.65
Global gene expression differences between blood- and lymphatic-specific human dermal microvascular endothelial cells 2.63
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 2.63
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 2.63
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 2.63
Differentially expressed vascular development genes for iPSC-ECs from CDI 2.61
The human blood-nerve barrier transcriptome 2.57
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 2.57
Microglia innatly develop within cerebral organoids 2.57
Comparative Transcriptome analysis of hESCs- and iPSCs-derived lentoid body 2.56
Single cell transcriptome of peritoneal cells 2.56
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics. 2.56
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 2.56
Transcriptional profiling of microglia; current state of the art and future perspectives 2.53
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 2.52
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 2.51
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 2.49
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 2.45
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 2.45
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 2.44
RNA-seq analysis of AML cells in response to ASLAN003 2.44
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 2.44
Dysregulated immune system networks in war veterans with PTSD 2.39
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 2.38
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 2.37
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 2.37
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 2.3
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 2.3
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 2.28
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 2.25
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 2.24
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 2.22
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 2.22
Characterization of sperm lncRNA and its differently expression in the sperm of asthenozoospermic patients 2.22
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 2.21
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 2.21
Leucegene: ALL sequencing 2.17
RNA-Seq analysis of human neutrophils isolated by different protocols (Polymorphprep and negative selection) and incubated with and without in vitro cytokine stimulation 2.14
RNA-Seq and expression data from human adipose tissue 2.13
Tissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases 2.13
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 2.13
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 2.11
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 2.11
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 2.09
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 2.06
Neonatal and adult human testis defined at the single-cell level 2.06
Postnatal lipids drive hepatocyte maturation 2.03
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 2.03
Clinker: visualizing fusion genes detected in RNA-seq data 2.01
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 2.0
Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants 2.0
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 1.98
Whole transcriptome profile of citrulline-specific B cells from patients with rheumatoid arthritis 1.97
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 1.91
ChIP-seq and RNA-seq from human lymphoma cell lines 1.9
RNA-seq data from human lymphoma cell lines 1.9
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 1.9
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 1.9
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 1.87
Atheroprotective flow alters EZH2/H3K27me3 dependent transcriptional profile in human endothelial cells 1.86
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 1.86
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 1.84
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 1.82
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 1.82
Human cells contain natural double-stranded RNAs with potential regulatory capacity 1.81
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 1.8
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 1.8
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 1.79
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 1.78
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 1.76
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 1.76
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 1.75
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 1.75
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 1.74
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 1.72
Transcriptome of Stabilin-1 siRNA transfected human monocytes 1.71
Macrophage Ad5f35 M2 Challenge 1.69
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 1.68
Whole blood RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 1.67
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 1.67
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 1.67
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 1.65
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 1.64
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 1.63
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 1.62
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 1.61
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 1.61
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 1.6
Pharmacologic inhibition of STAT5 in AML 1.6
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 1.6
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 1.6
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 1.6
Transcription control by the ENL YEATS domain in acute leukemia 1.6
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 1.6
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 1.59
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 1.59
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 1.57
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 1.56
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 1.54
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 1.54
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 1.54
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 1.51
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 1.51
RNA-sequencing analysis of human fibrolamellar hepatocellular carcinoma and 4 maturational stages of the human hepatobiliary system 1.51
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 1.49
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 1.49
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 1.49
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 1.48
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 1.48
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 1.47
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 1.45
Comprehensive comparative analysis of 5’ end RNA sequencing methods 1.45
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 1.44
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 1.41
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 1.41
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 1.4
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 1.4
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 1.38
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 1.37
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 1.36
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 1.35
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 1.35
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 1.33
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 1.33
Genome-wide discovery of human splicing branchpoints 1.31
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 1.3
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 1.28
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 1.28
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 1.28
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 1.28
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 1.26
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 1.26
TT-Seq captures the human transient transcriptome 1.23
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways 1.23
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 1.23
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 1.23
ENCODE Cold Spring Harbor Labs Long RNA-seq 1.23
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 1.23
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 1.22
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 1.22
Efficient derivation of microglia-like cells from human pluripotent stem cells 1.21
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 1.2
Effect of from Human Umbilical Vein Endothelial Cells 1.19
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 1.17
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 1.17
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia 1.16
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia (RNA-Seq) 1.16
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 1.15
RNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls 1.14
miRNAs affected by antagomiR-17 treatment 1.14
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 1.14
RNA-seq study reveals unique transcriptome expression in systemic lupus erythematosus patients with distinct autoantibody profile 1.13
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 1.12
Global gene expression profile of dasatinib-resistant RCH-ACV cells 1.12
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 1.11
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 1.1
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 1.1
Endothelial gene expression analysis 1.1
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 1.09
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 1.08
Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels 1.08
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 1.07
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 1.03
RNA-seq of primary patient AML samples 1.03
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 1.02
Targeting MTHFD2 in Acute Myeloid Leukemia 1.01
Intrinsic Plasma Cell Differentiation Defects in BENTA Patient B cells 0.99
Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells 0.97
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.96
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.95
Bone marrow derived human B cells [normal proB] 0.95
Widespread intronic polyadenylation diversifies immune cell transcriptomes 0.92
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding 0.9
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 0.89
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 [stranded] 0.82
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 0.8
RNA-seq analysis of the human fetal kidney. 0.79
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis 0.78
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 0.77
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 0.77
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 0.76
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 0.76
RNA expression analysis upon JMJD1C depletion 0.74
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 0.74
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 0.73
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 0.73
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] 0.71
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells 0.71
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.7
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.69
A novel tumor-associated myeloid cell population inhibits antigen-specific immune responses in cancer patients 0.68
Genome-wide Analysis of Chromatin Interactions in Human Cells 0.68
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 0.66
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.65
The role of m6A/m-RNA methylation in stress response regulation 0.65
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.65
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 0.64
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 0.63
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 0.63
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 0.63
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 0.59
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 0.59
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 0.57
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 0.57
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 0.56
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 0.56
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 0.49
Leucegene: AML sequencing (part 6) 0.47
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 0.46
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 0.43
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 0.38
Transcriptome-wide response to synthetic chromatin protein PcTF 0.38
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 0.37
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 0.35
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 0.34
quanTIseq: quantifying immune contexture of human tumors 0.33
Gene expression profiling of leukemia cells following asparagine depletion 0.33
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 0.33
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 0.33
Genome-wide mapping of TEL-AML1 targets in acute leukemia 0.32
Transcriptome sequencing of K-562 cells 0.32
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 0.31
Specific molecular signatures underlie response to decitabine in CMML 0.3
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.3
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 0.3
Neutrophils RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 0.28
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 0.28
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 0.28
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 0.27
RNA sequencing of T-ALL (COG study) 0.26
Analyses of T-ALL (COG study) 0.26
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 0.25
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 0.24
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 0.22
TAF1 is critical for AE driven leukemogenesis 0.22
In search for materials able to be colonized by a normal endothelium: сharacterization and NGS gene expression profiling of human primary endotheliocytes cultivated on electrospun 3D matrices 0.22
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 0.21
circNFIB suppresses lymphatic metastasis of pancreatic cancer 0.18
Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq] 0.18
Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor 0.17
Transcriptome analysis of diverse cell types infected with human cytomegalovirus 0.17
Expression analysis of the TAF1 syndrome 0.16
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 0.14
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 0.13
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 0.12
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 0.11
Vammin induces a highly efficient angiogenic response through VEGFR-2/NRP-1 and bypasses the regulatory function of VEGFR-1 0.1
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 0.09
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.08
Transcriptomic analysis of human coronary artery endothelial cells stimulated with TNF-alpha in the presence and absence of ACSL3 siRNA 0.08
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.08
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 0.06
SOX11 knockdown in B-ALL cell lines 0.06
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.04
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 0.04
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.04
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 0.02
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 0.02
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 0.02
Transcriptomes in healthy and CHB fetal hearts 0.02
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 0.01
U2AF1 mutations alter splice site recognition in hematological malignancies 0.01


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