Gene Query: MAP2K4

Dataset Description Geneva Score
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 48.56
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 42.49
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 34.33
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 33.07
Differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 28.49
mRNA differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 28.49
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 26.26
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 25.49
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 25.49
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 25.32
RNA-seq analysis to identify the genes regulated by p53-SET interplay 22.04
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 21.07
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 18.78
Knockdown of ADNP in HCT116 colon cancer cells 16.85
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 16.14
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 16.01
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 14.95
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 14.31
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 13.33
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 13.28
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 12.67
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 12.67
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 12.36
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 11.9
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 11.83
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 11.83
RNAseq Analysis in glioblastoma cells treated with Mepazine 11.69
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 11.33
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 11.06
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 11.0
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 11.0
FBXW7 modulates stress response by post-translational modification of HSF1 10.9
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 10.9
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 10.51
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 10.51
Nutritional control of protein translation 10.22
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 10.05
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 9.94
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 9.94
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 9.85
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 9.75
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 9.74
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 9.53
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 9.5
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 9.47
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 8.95
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 8.89
Transcriptome analysis upon C6orf203 silencing 8.38
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 8.11
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 8.08
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 8.04
METTL3 promotes translation in human cancer cells 8.0
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 7.97
Functional role of SLIT2 and ROBO1 in trophoblasts 7.87
Transcriptomic and gene ontology profiling of the human corneal cell types 7.87
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 7.86
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 7.66
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 7.56
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 7.56
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 7.52
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 7.52
Identification of Nrf2 regulated genes by RNA sequencing 7.47
Nrf2 regulated genes in A549 cells 7.47
Tracking of dCas9-methyltransferase footprints 7.47
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 7.39
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 7.25
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 7.08
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 7.08
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 7.02
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 7.0
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 6.99
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 6.98
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 6.98
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 6.97
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 6.88
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 6.87
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 6.83
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 6.83
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 6.76
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 6.66
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 6.66
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 6.58
Cleavage Factor Im as a key regulator of 3’ UTR length 6.54
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 6.44
Transcriptomic analyssis following EHMT1/2 inhibition 6.41
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 6.37
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 6.36
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 6.32
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 6.23
RNA-Seq in neutrophils from Antiphospholipid Syndrome 6.22
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq) 6.21
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation 6.21
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 6.18
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 6.11
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 6.11
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 6.11
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 6.1
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 6.06
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 5.95
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 5.94
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 5.93
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 5.92
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 5.9
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 5.9
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 5.88
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 5.87
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 5.87
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 5.82
Gene expression in PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition. 5.82
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 5.8
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 5.8
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 5.8
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 5.8
RNAseq in Alzheimer's Disease patients 5.77
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 5.72
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 5.71
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 5.7
Paxillin regulates genomic networks in prostate cancer [C4-2] 5.64
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 5.63
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 5.63
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 5.61
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 5.6
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 5.5
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 5.47
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 5.42
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 5.41
A transcriptome-wide divergence in protein translation scales with LIN28B expression 5.38
Regulation of protein translation during mitosis 5.38
SLIGRL-induced gene expression changes in NHEK cells 5.35
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 5.35
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 5.35
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 5.34
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 5.3
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 5.25
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 5.24
Selective suppression of endothelial cytokine production by progesterone receptor 5.22
Selective suppression of endothelial cytokine production by progesterone receptor [RNA-seq] 5.22
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 5.21
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 5.17
Examining serotonergic neuron differentiation from human iPSCs 5.15
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 5.12
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 5.12
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 5.09
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 5.08
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 5.07
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 5.06
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 5.06
RNA sequencing analysis of selumetinib-resistant CRC cells lines 5.04
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 5.01
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 5.01
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 5.0
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 5.0
Transcriptomic analysis of LSD1 4.98
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 4.98
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 4.96
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 4.96
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 4.96
Gene expression in skeletal muscle in older individuals subject to ten days of complete bed rest. 4.96
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 4.91
Noncoding regions are the main source of targetable tumor-specific antigens 4.91
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 4.88
Ribosomal footprinting of MDA-Parental and MDA-LM2 4.87
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 4.86
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 4.84
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 4.8
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 4.8
CD95/Fas ligand mRNA is toxic to cells 4.79
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 4.79
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 4.77
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 4.77
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 4.75
Effect of drugs on transcriptomic profiles 4.75
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 4.74
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 4.74
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 4.74
The role of CFTR in islet function 4.71
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 4.7
Alteration of the microRNA network during the progression of Alzheimer’s disease 4.69
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 4.68
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 4.67
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 4.67
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 4.66
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 4.66
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 4.63
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 4.6
The Glioma-Infiltrating T Cell Receptor Repertoire 4.59
MCF-7 as a model for functional analysis of breast cancer risk variants 4.58
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 4.56
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 4.55
High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues 4.54
The evolution of N6-methyladenosine in primates 4.54
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 4.53
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 4.51
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 4.5
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 4.5
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 4.5
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 4.49
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 4.49
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 4.48
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 4.44
Chromatin-informed inference of transcriptional programs in gynecologic cancers 4.44
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 4.43
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 4.4
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 4.38
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_1A_PI3K_RNA-seq] 4.34
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 4.34
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 4.29
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 4.29
Dtx3L and Androgen Signaling in Prostate Cancer 4.28
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 4.27
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 4.27
RNAseq of HEK293 cells after Chtop knockdown 4.27
Co-transcriptional loading of RNA export factors shapes the human transcriptome 4.27
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 4.26
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 4.24
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines (mRNA-Seq) 4.23
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines 4.23
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 4.22
RNA sequencing of primary human platelets and in vitro cell lines 4.2
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 4.18
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 4.18
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 4.17
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 4.15
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 4.15
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 4.11
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 4.11
Total RNA-seq in ALL-SIL upon TLX1 knockdown 4.1
MYC dependent mRNA translation shapes gene expression and cell biology 4.09
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 4.09
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 4.09
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 4.06
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 4.03
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 4.02
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 4.02
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 3.99
Mitochondrial dsRNA triggers antiviral signalling in humans 3.95
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 3.93
MYCL and EP400 are required for Max and MCPyV mediated gene activation 3.93
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 3.92
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 3.92
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 3.9
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 3.9
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 3.89
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 3.88
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 3.88
Seletive inhibition of CDK9 in DLBCL cell lines 3.82
SLAM-seq for K562 endogenous mRNA decay 3.8
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics. 3.77
Repurposing of promoters and enhancers during mammalian evolution 3.75
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 3.74
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 3.71
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 3.71
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 3.66
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 3.66
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 3.64
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 3.64
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 3.64
Global analysis of alternative splicing regulated by RBM10 3.64
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 3.63
Human neutrophil genome during PMA- and E. coli encounter-induced activation 3.61
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 3.61
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 3.61
LINE-2 transposable elements are a source of functional human microRNAs and target sites 3.6
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 3.6
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 3.6
R430: A potent inbibitor of DNA and RNA viruses 3.58
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 3.58
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 3.57
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 3.57
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 3.57
Mutational landscape of splicing genes and functional consequences across 33 cancer types 3.56
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  3.55
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 3.54
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 3.52
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 3.49
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 3.49
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 3.47
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 3.45
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 3.44
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 3.39
Low H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 3.38
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 3.38
Gene expression profile of human iPSC-derived nephron progenitor cells 3.35
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 3.35
Molecular Criteria for Defining the Naive Human Pluripotent State 3.35
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 3.35
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis 3.33
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 3.33
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 3.33
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 3.3
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 3.29
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 3.27
RNA transcriptome analysis during HSV-1 infection 3.27
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 3.2
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 3.17
Zone dependent distinctive gene expression profile of the normal human liver tissue 3.13
Regulation of poly(A) tail and translation during the somatic cell cycle 3.08
Conservative alteration of chromosomal expression pattern across human solid tumor types 3.08
Effect of CHKA knockdown on C4-2 cell transcriptome 3.03
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 3.03
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 3.01
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 3.0
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 2.97
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 2.97
Effect of PRDM11 depletion in U2932 cells 2.97
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 2.93
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 2.93
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 2.9
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 2.89
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 2.88
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 2.8
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 2.77
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 2.75
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 2.75
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 2.74
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 2.71
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 2.69
CDK12 mediated transcriptional regulation in U2OS cells 2.68
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 2.68
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 2.64
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 2.58
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.58
Splicing and epigenetic factors jointly regulate epidermal differentiation 2.56
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 2.54
Gene Expression Profiling of WT and KDM3A Knocked out Cell 2.53
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 2.53
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 2.53
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 2.53
Epigenetic reprogramming of melanoma cells by vitamin C treatment 2.52
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 2.5
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 2.49
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 2.48
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 2.48
single cell RNA-seq from GM12878 (ENCSR673UIY) 2.45
Dysregulated immune system networks in war veterans with PTSD 2.44
Gene expression profiles of ibrutinib-responsive and ibrutinib non-responsive cells in ERBB4 expressing cancer cell lines 2.44
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 2.42
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 2.42
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 2.39
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 2.32
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 2.29
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 2.24
The MEF2B Regulatory Network 2.22
The MEF2B Regulatory Network - RNA-seq data 2.22
Human Treg NaCl stimulation 2.21
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 2.19
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 2.18
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 2.17
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 2.17
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 2.16
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 2.14
An siRNA screen identifies CHD4 as a target for epigenetic therapy 2.13
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 2.11
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 2.05
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 2.05
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 2.03
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 1.98
Loss of CREBBP results in gene expression repression in lymphoma cells 1.98
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 1.96
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 1.96
RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways 1.95
Unbiased evaluation of cell-free amniotic fluid transcriptome of term and preterm infants to detect fetal maturity 1.95
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with pancreatic carcinoma 1.93
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 1.93
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 1.92
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 1.88
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 1.84
Determining mRNA half-lives on a transcriptome-wide scale 1.83
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 1.82
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 1.82
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.81
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 1.79
Downregulation of DDX5/DDX17 and REST 1.75
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 1.74
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 1.74
The age and genomic integrity of neurons after cortical stroke in humans 1.72
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 1.69
Induction of Cardiomyocyte Proliferation [pz-822_human] 1.69
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 1.67
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.66
RNA Sequencing of Human iPS derived Cardiomyocytes 1.66
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 1.64
Transcriptome-wide identification of CELF2 functional targets in T cells 1.64
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 1.62
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 1.61
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 1.61
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 1.61
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 1.58
Tpl-2 and MEK small molecule inhibitors 1.58
Tpl-2 small molecule project 1.58
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 1.58
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 1.55
Gene expression profile in breast cancer cells 1.55
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 1.55
Gene expression alterations of pancreatic intraepithlial neoplasia 1.54
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 1.52
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 1.5
Multiple sclerosis and EAE 1.46
Human optic chiasm from healthy controls and multiple sclerosis patients 1.46
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 1.44
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 1.44
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 1.41
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 1.37
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 1.34
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 1.31
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.27
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 1.27
Modeling Human Cancer-induced Cachexia (Human) 1.27
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.27
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 1.26
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.24
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.24
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.23
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus 1.23
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 1.2
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 1.2
Identification of expressed and conserved human non-coding RNAs 1.18
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 1.16
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 1.16
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.11
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 1.11
Small-molecule targeting of brachyury transcription factor addiction in chordoma 1.11
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 1.08
Isolation and Functional Interrogation of Adult Human Prostate Epithelial Stem Cells at Single Cell Resolution 1.05
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 1.04
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 1.04
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 1.02
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 1.02
Transcriptome profiling of A2M treated A549 Cell Line Samples 1.0
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 1.0
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 0.95
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 0.91
Human Treg IL-12 stimulation 0.9
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.89
Defective structural RNA processing in relapsing-remitting multiple sclerosis 0.88
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.87
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.87
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 0.82
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 0.82
The contribution of Alu exons to the human proteome 0.81
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 0.8
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.79
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 0.78
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 0.77
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 0.75
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 0.75
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.74
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.73
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 0.72
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 0.72
Codon usage optimization in pluripotent embryonic stem cells [tRNA sequencing] 0.69
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 0.67
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 0.67
Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants 0.65
FOXP1 orchestration of ASD-relevant signaling pathways. 0.62
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 0.6
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.54
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 0.46
Assessing placental maturity through histological and transcriptomic analyses in idiopathic spontaneous preterm birth 0.45
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: Comparison of gene expression profiling approaches 0.44
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: Comparison of gene expression profiling approaches [RNA-Seq] 0.44
MAIT cell RNA sequencing 0.44
Transcriptome-wide modulation of splicing by the exon junction complex 0.44
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 0.43
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.43
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 0.43
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.42
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.41
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.37
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 0.34
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 0.33
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 0.29
Human Treg IFNg/IL-10 subpopulations 0.29
An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS 0.29
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 0.28
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.28
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 0.21
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 0.21
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 0.2
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 0.2
HBEC-shp53-PCHD7 0.18
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.18
Transcriptome profiling of 5 human adenocarcinoma cell lines 0.17
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 0.17
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.17
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 0.16
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 0.16
Modulation of nonsense-mediated decay by rapamycin 0.15
The transcriptome and chromatin accessbility landscape of mammalian germline 0.15
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.13
Identification of global XBP1s target gene expression in human prostate cancer cells 0.13
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.12
Expression analysis of the TAF1 syndrome 0.09
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 0.09
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 0.09
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.08
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.07
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.05
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.05
HEK293 TFAM Knockout Expression Study 0.0


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