Gene Query: MAP3K2

Dataset Description Geneva Score
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 36.83
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 30.27
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 25.99
hTERT promotes cell adhesion and migration independent of telomerase activity 25.92
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 23.6
ZIKV infection of monocytes activates inflammasome pathways 23.58
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 23.31
Human cell line and subcutaneous tumor 22.84
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 22.18
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 20.55
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 20.1
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 19.35
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 19.34
Antibody-Mediated Inhibition of MICA/B Shedding Promotes NK Cell-Driven Tumor Immunity 19.01
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 18.1
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 18.03
RNA sequencing of GlyH-101-treated MCF-7 cell line 17.99
Gene expression profiling of human CD19+ B cells and EBV transformed lymphoblastoid cell lines (LCLs) 17.51
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 17.43
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 17.42
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 17.32
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 17.1
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 16.89
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 16.89
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 16.62
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 16.52
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 16.42
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 16.42
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 16.33
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 16.3
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 16.21
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 16.09
Human neutrophil genome during PMA- and E. coli encounter-induced activation 16.09
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 16.05
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 15.49
Impact of dieldrin on transcription in Jurkat T cells 15.23
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 15.1
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 14.9
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 14.78
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 14.7
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 14.32
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 14.04
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 14.04
Effect of from Human Umbilical Vein Endothelial Cells 14.03
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 14.02
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes 13.94
Active translatome profiling with RiboLace in MCF7 cells 13.81
Transcriptomes of oxLDL exposed trained monocytes 13.79
oxLDL exposed trained monocytes 13.79
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 13.48
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 13.47
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 13.44
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 13.17
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 13.17
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  13.14
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 13.08
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 13.03
Pharmacologic inhibition of STAT5 in AML 13.0
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 12.97
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 12.96
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 12.89
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 12.86
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 12.86
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq] 12.52
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 12.51
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 12.5
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 12.5
Transcriptome analysis of U87 cells upon LINC00152 knockdown 12.46
Global gene expression profiling from LeuCAG3'tsRNA depleted- HeLa and HCT-116 cell lines through 50 base pair paired-end RNA-seq 12.37
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. 12.19
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 12.13
High-throughput sequencing of PROMPT-enriched samples. 12.09
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 12.02
Gene expression profiling of leukemia cells following asparagine depletion 11.92
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 11.82
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 11.81
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 11.73
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 11.61
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 11.51
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 11.43
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 11.4
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 11.37
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 11.37
Transcriptomes change differerntly in differernt cancer cells upon EPZ-6438 treatment 11.32
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 11.19
Global response to chemotherapy-induced apoptosis 11.14
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 11.12
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 11.07
Ribosomal footprinting of CN34-Parental and CN34-LM1a 11.03
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 11.02
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 10.99
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 10.85
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) 10.82
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 10.78
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 10.77
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 10.61
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 10.58
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 10.46
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 10.43
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 10.43
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 10.36
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 10.34
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 10.25
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 10.25
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 10.24
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 10.19
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 10.17
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 10.16
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 10.16
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 10.06
Human HAP1 cells before and after nutrient deprivation 10.06
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 9.98
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 9.98
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 9.97
Identification of the role of polydom in neurofibromas 9.92
An improved method for circular RNA purification that efficiently removes linear RNAs containing G-quadruplexes or structured 3’ ends 9.92
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 9.9
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 9.87
The regulartory role of ZCCHC24 in splicing machinery 9.82
RNA-Seq with and without RNase treatment in PCa cell lines 9.77
Electronic cigarettes 9.74
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 9.71
MOF acetyl transferase regulates transcription and respiration in mitochondria 9.7
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 9.65
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 9.64
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 9.58
Knockdown of ADNP in HCT116 colon cancer cells 9.55
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 9.54
RNA sequencing of mechanically strained NHEKs and control NHEKs 9.49
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 9.44
Tracking distinct RNA populations using efficient and reversible covalent chemistry 9.4
The role of FAM46C in myeloma cells 9.39
The role of FAM46C in myeloma cells [sequencing] 9.39
RNA-Sequencing of HepG2 cells treated with TGFBeta 9.31
High-Throughput Kinetic Analysis of Fractional Killing 9.27
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 9.25
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 9.24
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 9.22
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 9.21
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 9.19
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 9.18
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 9.12
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 9.12
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 9.1
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 9.1
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 9.1
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 9.02
RNA sequencing of heart samples of myotonic dystrophic (DM1) patients 8.94
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 8.92
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 8.91
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 8.89
Genome-wide functional assessment of enhancer activities in the human genome 8.85
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 8.8
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing 8.78
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 8.73
Systematic discovery of endogenous human ribonucleoprotein complexes 8.72
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 8.72
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 8.7
Tumor exosome integrins determine organotropic metastasis 8.69
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 8.68
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 8.68
Defective structural RNA processing in relapsing-remitting multiple sclerosis 8.67
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 8.61
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 8.61
NAPRT activation of macrophages 8.59
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 8.5
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 8.49
EP400 is required for Max and MCPyV mediated gene activation 8.47
Short and Long RNA sequencing of human mature erythrocytes 8.44
CD73 knockdown effect in pancreatic cancer cell lines 8.44
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 8.43
Differential expression of genes in AD169-infected MRC5. 8.42
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 8.38
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 8.38
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 8.38
Transcriptomes of human monocytes after ex vivo exposure to uric acid 8.36
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 8.33
Ribosomal footprinting of MDA-Parental and MDA-LM2 8.22
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 8.13
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 8.06
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 8.06
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 8.05
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 8.01
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 7.99
Genetic disruption of COX-1 inhibits multiple oncogenic pathways 7.99
Differential analysis of gene regulation at transcript resolution by RNA-Seq 7.99
Differential analysis of HOXA1 in adult cells at isoform resolution by RNA-Seq [Illumina] 7.99
Comparative Analysis of the Transcriptome of Latent Autoimmune Diabetes (LADA) Patients from Eastern China 7.96
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 7.95
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 7.95
Transcriptome profiling of Caki2 cells re-expressing Polybromo-1 (PBRM1) 7.92
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation 7.92
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 7.9
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction 7.9
Sensing self and nonself circular RNAs 7.9
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 7.89
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. 7.82
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 7.81
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 7.79
Transcriptome analysis in Neobractatin treated cells 7.78
Profiling of escape kinetics of viruses subjected to RNAi 7.74
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 7.74
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 7.71
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 7.69
Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms 7.66
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 7.64
PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells 7.55
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 7.49
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 7.49
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 7.48
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 7.48
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 7.4
Determination of tRNA aminoacylation levels by high throughput sequencing 7.39
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 7.38
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 7.29
RNA sequencing to compare gene expession in control and PF228-treated hepatic stellate cells 7.23
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 7.23
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells 7.17
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 7.17
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 7.15
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 7.13
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 7.11
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 7.11
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 7.1
Transcriptomic insights into human decidual and peripheral blood CD8 T cells 7.08
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 7.04
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 6.97
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 6.91
IRF2 is a master regulator of human keratinocyte stem cell fate 6.91
TLR2 dimerization blockade allows generation of homeostatic intestinal macrophages under acute colitis challenge 6.91
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 6.86
Genome-Wide Transcriptional Effects of the Anti-Cancer Agent Camptothecin 6.84
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 6.84
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 6.79
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 6.77
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 6.75
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 6.75
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 6.72
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 6.62
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 6.59
The contribution of Alu exons to the human proteome 6.53
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 6.48
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 6.45
Conservative alteration of chromosomal expression pattern across human solid tumor types 6.39
MYCL and EP400 are required for Max and MCPyV mediated gene activation 6.39
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 6.37
Effect of PBK knockdown on C4-2 cell transcriptome 6.33
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 6.31
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 6.29
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 6.27
CD1c+ dendritic cell activation by Plasmodium falciparum-infected red blood cells 6.26
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 6.24
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 6.22
Global Mapping of Human RNA-RNA Interactions 6.22
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 6.21
Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice 6.18
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 6.17
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 6.14
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 6.09
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 6.09
Transcriptomic Analysis of Endothelial Cells from Fibrovascular Membranes in Proliferative Diabetic Retinopathy 6.06
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 6.03
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 6.03
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 6.01
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 6.01
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 5.98
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 5.98
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 5.95
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 5.93
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 5.84
A sister of NANOG regulates genes expressed in pre-implantation human development 5.82
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 5.8
Genome-wide DNA accessibility maps and differential gene expression using ChIP-seq, ATAC-seq and RNA-seq for the human secondary fibroblast cell line hiF-T and whole worms with and without knockdown of FACT complex 5.77
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 5.76
Chromatin-informed inference of transcriptional programs in gynecologic cancers 5.74
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 5.74
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 5.73
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 5.69
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 5.64
The transcriptome effect of overexpressing EZH2 in MCF7 5.62
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 5.54
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 5.49
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 5.49
Exercise-induced transcriptome changes in skeletal muscle adapted to aerobic training 5.48
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 5.47
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 5.44
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 5.44
Small-molecule targeting of brachyury transcription factor addiction in chordoma 5.4
The Wnt/β-catenin and RAS-ERK Pathways were Activated in Tissues of Chemotherapy-Resistant Gastric Cancer PDX Tumor 5.4
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 5.39
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 5.25
mRNA-Seq profiling of human developing kidney 5.22
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 5.18
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 5.07
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 5.02
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 5.02
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 4.97
CDK12 mediated transcriptional regulation in U2OS cells 4.92
Pain-driven transcriptome changes in synovium of knee osteoarthritis patients 4.9
RNA Seq of HMVEC under hypoxia 4.83
Endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates 4.83
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 4.8
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 4.76
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 4.73
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 4.73
Expression data from miR340 overexpressing human A549 cells 4.71
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 4.68
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 4.67
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 4.67
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 4.65
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 4.56
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 4.55
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 4.53
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 4.53
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 4.48
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis 4.48
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 4.45
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 4.43
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 4.43
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 4.36
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 4.32
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2) 4.32
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 4.29
Silencing SPIB in attached and floating state of H1703 lung cancer cells 4.27
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 4.25
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 4.24
An siRNA screen identifies CHD4 as a target for epigenetic therapy 4.24
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 4.21
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 4.2
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 4.19
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 4.18
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 4.03
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 4.0
Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma 4.0
Gene expression changes due to PARP knockdown in human cells 3.92
Gene expression in skeletal muscle in older individuals subject to ten days of complete bed rest. 3.9
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 3.87
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 3.69
An optimization system for isolating and sequencing of single human colon cancer cells 3.63
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 3.59
Regulation of poly(A) tail and translation during the somatic cell cycle 3.58
Gene expression analysis of human hepatocellular cancers 3.58
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 3.49
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 3.49
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 3.47
Noncoding regions are the main source of targetable tumor-specific antigens 3.37
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 3.32
Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates 3.22
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 3.22
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 3.22
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 3.21
RNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls 3.19
Landscapes of gene translation in hepatocellular carcinoma tumors revealed by ribosome profiling 3.17
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 3.16
Transcriptome-wide response to synthetic chromatin protein PcTF 3.12
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 3.07
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 3.06
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 3.06
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 3.06
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 3.05
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 3.04
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 3.04
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 3.01
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 3.01
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 2.92
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.92
Peripheral whole blood mRNAs and lncRNAs expression analysis in eosinophilic asthmatics 2.85
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 2.84
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 2.84
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 2.84
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 2.83
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 2.78
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 2.78
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 2.73
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 2.72
Exploring ILF2 regulatory genes by next-generation sequencing 2.71
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 2.7
Interphase condensins regulate ligand-depedent enhancer activation 2.69
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 2.69
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 2.67
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 2.67
The mRNA expression analysis of psoriasis skin lesion mesenchymal stem cell 2.61
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 2.58
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 2.58
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with colorectal carcinoma 2.52
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 2.47
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 2.47
Transcriptome of human ILC2s; primary vs IL-1b-primed 2.46
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 2.39
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 2.38
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 2.37
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 2.37
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 2.36
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression 2.36
A novel non-canonical signaling pathway mediates TGF-β1-induced glucocorticoid insensitivity in epithelial cells 2.35
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 2.33
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 2.28
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 2.26
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 2.25
RNAseq of cell lines with knocked in ESR1 mutations 2.24
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 2.21
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus 2.1
Human macrophages exhibit high activity to clear intracellular biovar Microtus strain of Y. pestis 2.08
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 2.08
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis 2.02
Transcription elongation regulates genome 3D structure 1.99
RNA-Seq of PRMT1 overexpression ECA109 cells 1.97
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 1.96
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 1.92
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 1.92
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 1.91
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 1.9
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 1.87
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 1.83
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 1.77
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 1.77
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 1.74
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 1.72
STX4 Over-Expression in Human islets 1.69
Circular RNA expression signature of low-glucose-treated MIA PaCa-2 cells 1.69
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 1.69
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 1.59
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 1.56
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 1.56
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 1.5
Induction of Cardiomyocyte Proliferation [pz-822_human] 1.47
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 1.47
RNA-sequencing study of peripheral blood monocytes for chronic periodontitis 1.45
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 1.44
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 1.44
RNA-seq analysis of control and Myc-induced U2OS cells 1.37
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 1.37
Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles 1.32
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 1.32
Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells. 1.29
Transcriptional changes in lymphoma cells induced by LSD1 depletion 1.16
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 1.16
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.1
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 1.08
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells 1.08
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells [RNA-Seq] 1.08
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 1.06
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 1.06
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 1.06
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.05
RNA seq comparison between scrambled and shGRP78 cells 1.01
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells 0.97
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 0.97
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 0.9
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 0.9
Activity-dependent transcriptional changes in human neurons 0.86
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.83
Specific molecular signatures underlie response to decitabine in CMML 0.83
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 0.77
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 0.75
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 0.69
RNA-Seq of CD4+ T cells treated with AS1842856 or DMSO 0.67
Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants 0.61
Transcriptome of U251 cells overexpression complement component 7 0.59
Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease 0.58
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 0.56
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.55
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 0.54
The NFkB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells 0.53
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.51
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.48
The role of the Calcium-Sensing receptor in colorectal cancer 0.46
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.45
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.45
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 0.43
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.42
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.42
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.41
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 0.4
Mitochondrial dsRNA triggers antiviral signalling in humans 0.35
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 0.32
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction. 0.31
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction [RNA-seq] 0.31
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 0.31
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.3
Transcriptome-wide modulation of splicing by the exon junction complex 0.27
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.27
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 0.27
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 0.26
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 0.25
A code of mono-phosphorylation modulates the function of RB. 0.22
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 0.22
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 0.22
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 0.21
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 0.19
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 0.16
Modulation of nonsense-mediated decay by rapamycin 0.15
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.07
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 0.04
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.04
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.03
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.01
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.0
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.0
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 0.0


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