Gene Query: MYC

Dataset Description Geneva Score
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 136.59
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 136.59
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 129.96
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 128.93
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 124.88
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 123.34
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 122.52
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 122.52
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation [RNA-Seq] 120.8
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation 120.8
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 120.48
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 112.42
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 111.49
Hijacking of stress response machinery by oncogenes in acute leukaemia 111.49
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 106.2
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 102.06
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 102.06
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 98.2
LNCaP treated with iBET 97.0
Uridylation by TUT4 and TUT7 marks mRNA for degradation 96.48
CD95/Fas ligand mRNA is toxic to cells 96.47
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 90.72
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 86.04
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 83.24
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 82.91
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 79.33
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 79.0
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma 76.72
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma (RNA-seq) 76.72
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 74.84
Dtx3L and Androgen Signaling in Prostate Cancer 72.69
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 68.56
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 66.81
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 64.38
RNA-Sequencing of HepG2 cells treated with TGFBeta 64.27
Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines 64.03
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 63.84
Androgen receptor programming in human tissue implicates HOXB13 in prostate pathogenesis [RNA-Seq] 62.62
Androgen receptor programming in human tissue implicates HOXB13 in prostate pathogenesis 62.62
Active translatome profiling with RiboLace in MCF7 cells 61.22
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 60.65
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 59.04
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 58.91
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 56.79
Interphase condensins regulate ligand-depedent enhancer activation 56.23
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 56.23
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 56.19
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 56.16
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 55.56
Estrogen Receptor Beta Impacts Hormone-Induced Alternative mRNA Splicing in Breast Cancer Cells 55.41
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 54.58
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 54.58
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 51.86
Transcriptome-wide analysis of adipose circular RNAs reveals their dynamic regulation in obesity and functional role in adipogenesis 51.67
Transcriptomic profiling of human CD34+ derived mast cells [RNA-Seq] 51.13
Landscape of human mast cell chromatin: a rich resource for identification of novel mediators and genetic drivers of allergic and inflammatory diseases 51.13
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 50.95
Chronic cadmium exposure decreases the dependency of MCF7 breast cancer cells on ERα 50.69
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 24h] 49.75
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 49.72
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 49.01
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq] 47.74
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 47.04
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 46.56
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 46.52
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 46.37
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 46.37
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 45.26
Differetially expressed genes after hTR overexpression in U2OS cells 45.16
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 44.39
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 44.39
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 44.29
Transcriptome-wide identification of CELF2 functional targets in T cells 44.28
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 44.12
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 44.12
Co-regulation of splicing by Rbfox1 and hnRNP M 43.96
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 43.96
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 43.89
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 43.73
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 43.1
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 43.09
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 42.64
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 42.23
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 41.72
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 41.72
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 41.35
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 41.35
Genome wide expression change by RNF168 knocking down in MCF-7 cells 41.25
PNET animal model: new insights (II) 40.9
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 40.27
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 39.99
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 39.99
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 39.74
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 39.46
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 39.4
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 38.51
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 38.42
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 38.42
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 38.17
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 37.95
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 37.71
Transcriptomic profiling of human peripheral blood-derived mast cells 37.71
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 37.5
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 37.28
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 37.2
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 37.13
HNRNPL and its RNA Targets in Prostate Cancer 36.95
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 36.95
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 36.81
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 36.7
RNA-sequencing of human tendon after injury 36.67
Gene expression analysis of dengue-infected cells 36.63
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 36.58
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 36.46
Appropriately Differentiated ARPE-19 Cells Regain a Native Phenotype and Similar Gene Expression Profile 36.42
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 36.15
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 35.96
Nm-seq finds thousands of modified 2’-O-methylation sites in mRNA with base precision 35.95
Total RNA-seq in ALL-SIL upon JQ1 inhibition 35.08
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 35.02
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 34.84
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 34.42
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 34.09
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 33.74
Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons 33.61
Irf9 function in immunity in mouse 33.61
Patient-derived luminal breast cancer xenografts with progestins 33.58
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 33.58
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 33.35
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 32.82
Developmental stage specific chromosome architecture in human erythroid cells 32.82
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 32.36
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 32.14
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 32.14
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 32.09
Comparison of microRNA Profiling Platforms 31.95
Comparison of microRNA Profiling Platforms (HTS) 31.95
Primary human trophoblast from term placenta 31.73
Solid phase chemistry to covalently and reversibly capture thiolated RNA 31.64
Role of COP1 on MAP kinase transcriptional output in melanoma 31.42
RNA-seq of young and quiescent MRC-5 human fibroblasts 31.17
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 31.16
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 31.02
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] 30.99
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells 30.99
The landscape of alternative splicing in aggressive prostate cancers 30.93
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 30.82
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 30.82
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 30.78
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 30.45
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 30.44
Effect of drugs on transcriptomic profiles 30.36
m6A-dependent regulation of messenger RNA stability 30.27
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 30.22
Maturation of human iNSCs 30.14
PGE2 mediated gene expression changes in human cervical stromal cells 29.36
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 28.71
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 28.71
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression 28.58
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 28.34
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 28.29
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 28.06
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis 28.02
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 27.89
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 27.83
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 27.69
Real-time observation of light-controlled transcription in living cells 27.61
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 27.58
Gene expression changes upon drug withdrawal (Mel888 cell line) 27.52
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 27.43
Gene expressions of H9s in different culture systems 27.35
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 27.21
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 27.21
Zone dependent distinctive gene expression profile of the normal human liver tissue 27.13
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 27.03
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 27.03
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 26.96
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 26.96
NR2F2 study 26.96
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 26.9
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 26.73
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 26.47
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 26.39
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 26.08
Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS 26.08
RNA-Seq analysis of breast cancer cells after shikonin treatment 26.03
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 25.3
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 25.29
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 25.19
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 25.19
mRNA Sequencing of Human PromoCells Using Random Primed mRNA-Sequencing Technique 25.07
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 24.75
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 24.7
BASP1 modifies the Tamoxifen response 24.63
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 24.43
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 24.29
Single-nucleotide-resolution mapping of HBV promoters using CAGE 24.27
RNA-seq differential expression studies: more sequence, or more replication? 24.1
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 23.99
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function 23.82
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 23.49
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 23.42
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 23.42
Forkhead domain mutations in FOXA1 drive prostate cancer cell progression 23.37
RNA-seq in LNCaP cell line overexpressing WT or mutant FOXA1 23.37
The MEF2B Regulatory Network - RNA-seq data 23.33
The MEF2B Regulatory Network 23.33
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 23.3
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 23.14
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 23.06
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 23.03
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 23.01
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 22.94
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 22.85
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 22.7
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 22.68
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 22.65
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 22.65
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 22.65
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 22.47
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 22.37
Nucleoporin-mediated regulation of cell identity genes 22.35
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 22.2
Transcriptomic profiling of HeLa cells infected with Salmonella Typhimurium 22.02
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 22.02
Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues 22.01
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 21.94
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 21.78
Effect of Hotair overexpression in human breast cancer cell lines 21.77
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 21.61
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 21.6
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 21.53
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 21.53
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 21.48
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 21.48
Viral infection enhances NK cell activation via Type I dependent pathways and can be utilized to enhance influenza-specific monoclonal antibody therapies 21.38
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 21.29
RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d) 21.15
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 21.06
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 21.06
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 21.05
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 21.03
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 21.02
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 21.01
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 21.01
IMP3 regulated gene expression in breast cancer cells 20.98
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 20.96
Genome wide expression change in LCC2 and MCF-7 cells 20.94
Role of microRNAs in the interaction between Salmonella and the host cell 20.92
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 20.89
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 20.89
Regulation of protein translation during mitosis 20.86
RNA-seq of MCF10A cells and CAF 20.82
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 20.69
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 20.68
Gene expression in PANC1 cells treated with Rakicidin 20.54
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 20.53
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 20.53
Human cells contain natural double-stranded RNAs with potential regulatory capacity 20.5
Gene Expression Profiling of SPOP Knocked Down Cell 20.5
Transcripotome analysis of different locations of hair follicles (bulb, bulge) in androgenetic alopecia 20.48
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 20.37
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 20.37
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 20.17
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 20.14
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 20.11
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 20.01
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 19.98
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 19.91
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 19.75
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 19.71
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 19.67
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 19.67
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 19.65
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 19.62
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 19.6
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 19.51
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 19.47
Effect of disulfiram treatment on pediatric high grade glioma 19.41
Discovering the anti-cancer potential of non-oncology drugs by systematic PRISM profiling 19.27
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 19.2
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 19.17
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and converts them into tumorigenic cells 19.13
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 19.12
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq] 19.11
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma 19.11
Statins modulate endothelial transcriptional profile by inhibiting EZH2 18.9
Primary Human B-cell Temporal Response to CD40L Stimulation 18.88
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 18.82
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 18.82
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 18.68
RNA-sequencing in irradiated and normal A549 cells. 18.65
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 18.64
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 18.64
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 18.54
RNA-seq analysis of differentiating human erythroblasts 18.47
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 18.41
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 18.38
Transcriptional profiles of normal human mature B cells 18.33
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 18.27
RNA-Seq of Kaposi’s sarcoma reveal alterations in glucose and lipid metabolism 18.27
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 18.16
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 18.0
Epigenome regulation during epidermal lineage commitment [RNA-seq] 17.75
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 17.75
Transcriptomic and gene ontology profiling of the human corneal cell types 17.64
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 17.58
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 17.56
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 17.53
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 17.49
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 17.43
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 17.28
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 17.03
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 17.02
RNAseq of T-ALL upon long non coding rna purturbation 16.85
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 16.82
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 16.68
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 16.66
Identification of HOXB13 target genes responsive to BET inhibitors 16.59
RNA-sequencing analysis examining how the Vibrio cholerae MARTX toxin and its inidividual effector domains modulate the transcriptome of human intestinal epithelial cells. 16.4
AMPK signaling for naïve pluripotency [Hs] 16.35
AMPK signaling for naïve pluripotency 16.35
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 16.35
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 16.27
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 16.26
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 16.26
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 16.24
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 16.24
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 16.13
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 16.13
p53 activity results in DNA replication fork processivity 16.12
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 16.12
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 16.08
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 16.08
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 15.89
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 15.89
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 15.85
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 15.81
RNA splicing alteration on glioblastoma and normal neural stem cells 15.64
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 15.63
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 15.59
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 15.59
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 15.59
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 15.52
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 15.5
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 15.5
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 15.35
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 15.35
Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms 15.32
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 15.25
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 15.25
mRNA expression levels in splenic human mononuclear cells of mock- and HIV-1-infected humanized mice 15.24
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 15.22
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 15.1
Hepatitis C virus functionally sequesters miR-122 15.04
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 15.04
Examining serotonergic neuron differentiation from human iPSCs 14.89
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 14.8
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 14.51
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 14.28
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 14.21
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 14.08
Cell responses to dysregulated VZV-induced cell-cell fusion 14.02
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 13.96
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 13.88
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 13.87
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 13.86
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 13.8
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 13.61
The effect of PPARG inhibition on human angiomyolipoma cells 13.6
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 13.29
Argonaute proteins couple chromatin silencing to alternative splicing 13.07
Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) 13.07
Anti-inflammatory effect of indoleacrylic acid (IA) 13.06
Uridylation by TUT4 and TUT7 marks mRNA for degradation [RNA-Seq] 12.93
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 12.8
MARCKS and lnc-MARCKS act as inflammation regulators 12.79
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 12.73
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 12.73
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 12.46
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 12.38
Neuronal Development And The Onset Of Electrical Activity In The Human Enteric Nervous System 12.38
Evaluating pre-clinical models for studying NASH driven HCC. 12.38
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 12.28
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 12.28
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 12.18
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 11.77
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 11.77
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 11.68
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 11.6
Subclonal cooperation drives metastasis through modulating local and systemic immune microenvironments 11.51
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 11.38
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 11.36
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 11.18
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 11.02
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 11.02
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 10.82
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 10.82
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 10.72
A High-Throughput Screen Identifies DYRK inhibitor ID-8 that Stimulates Human Kidney Tubular Proliferation 10.18
The effect of insulin on mRNA transcription of human pluripotent stem cells 9.95
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 9.92
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 9.92
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 9.81
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 9.76
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 9.59
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 9.59
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 9.27
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 9.25
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 9.23
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 9.09
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 8.56
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 8.48
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. 8.44
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism: Liver RNA profiles of lean non-diabetic, obese non-diabetic as well as obese diabetic humans. 8.44
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 8.39
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 8.26
A map of gene expression in neutrophil-like cell lines 8.17
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 8.15
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 8.05
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 7.94
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 7.93
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 7.93
Fibroblasts in cholesteatoma activate osteoclasts. 7.9
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 7.54
Mapping interactions for the TNIP2 hub protein 7.51
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 7.49
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 6.98
Transcriptome profiling of 5 human adenocarcinoma cell lines 6.91
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 6.71
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 6.66
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 6.66
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 6.56
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 6.54
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 6.52
Genome-wide mapping of TEL-AML1 targets in acute leukemia 6.5
Human Treg IFNg/IL-10 subpopulations 6.45
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 6.41
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 6.38
Parallel T-cell cloning and deep sequencing of the transcripts of human MAIT cells reveal stable oligoclonal TCRβ repertoire 6.35
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 6.27
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 5.86
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 5.86
MAIT cell RNA sequencing 5.85
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 5.84
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 5.84
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 5.84
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 5.8
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 5.77
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 5.73
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 5.52
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 5.52
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 5.42
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 5.42
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 5.31
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 5.12
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 4.97
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 4.95
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 4.88
MRTF activates TEAD-YAP target gene expression 4.71
RNA-sequencing of epicardial adipose tissue of patients with atrial fibrillation 4.67
Total RNA-Seq data from leukemic patients with complex structural variants 4.62
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 4.43
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 4.28
Positively selected enhancer elements endow tumor cells with metastatic competence 4.23
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 4.06
Canonical and non-canonical regulatory roles of androgen receptor variant 7 in prostate cancer 3.95
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 3.92
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 3.87
Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis 3.81
Expression patterns in chronic thromboembolic pulmonary hypertension 3.8
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 3.76
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 3.6
Novel Targeting of Transcription and Metabolism in Glioblastoma 3.59
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 3.5
ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle 3.42
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 3.19
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 3.14
DRB/GRO-Seq -/+ UV 2.89
Differentially Expressed Genes for Atrial Fibrillation Identified using RNA Sequencing from Paired Human Left and Right Atrial Appendages. 2.87
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 2.75
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 1.68
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 1.66
CDK12 mediated transcriptional regulation in U2OS cells 1.46
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 1.32
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 1.32
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 1.2
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 1.12
Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs) 0.91
RNA Seq of Alagille liver biopsies 0.86
Alagille_Nodder 0.86
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 0.46
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 0.26
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 0.21
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.17
Identification of miRNA-mRNA regulatory network for Human Atrial Aging 0.13
Identification of miRNA-mRNA regulatory network for Human Atrial Aging [mRNA] 0.13
Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2 0.1
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.05
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 0.02


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