Gene Query: NRN1

Dataset Description Geneva Score
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 118.51
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 100.79
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 91.31
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 91.03
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 79.15
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 75.09
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 75.09
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 69.13
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 60.52
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 60.52
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 57.09
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 54.61
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 54.61
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 54.5
RNA-seq data from human lymphoma cell lines 52.89
ChIP-seq and RNA-seq from human lymphoma cell lines 52.89
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 49.33
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 46.33
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 46.33
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 42.08
RNA-seq analysis of BAP1-depleted uveal melanoma cells 41.8
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 41.45
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 41.23
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 41.19
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 38.93
High level DNA repair gene expression in human ES cells 36.9
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 36.57
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 34.46
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 34.24
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 33.53
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  33.02
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 31.16
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 31.16
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 30.03
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 30.03
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 30.0
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 28.89
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 28.89
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 28.66
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 28.38
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 28.27
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 27.08
SRSF2 mutations impair hematopoiesis and alter exon recognition 26.93
RNA-Seq study of Cell lines rendered resistant to idelalisib and ibrutinib 26.79
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 26.09
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 25.9
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 25.9
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 24.89
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 24.85
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 24.72
RNA-seq analysis of AML cells in response to ASLAN003 24.51
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 24.45
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 24.41
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 24.18
Induced DNA demethylation, genome instability and transcription 22.62
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 22.62
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 22.52
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 22.04
HEXIM1 is induced by DHODH inhibition to suppress melanoma 22.04
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 21.12
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 21.01
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 20.37
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 20.12
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 19.98
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 19.98
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 19.95
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 19.63
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 19.23
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 18.26
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 18.04
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene (RNAseq) 16.9
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene 16.9
Aortic Valve Tissue: Stenosis vs. Sclerosis 16.8
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 16.5
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 16.46
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 16.16
Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 16.01
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 15.91
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 15.44
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 15.36
Reassessment of Exosome Composition 15.18
Transcriptome analysis of U87 cells upon LINC00152 knockdown 14.94
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 14.87
RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma 14.75
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 14.62
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 14.56
Next Generation Sequencing of human SMA and healthy control Motor Neurons 14.11
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 13.92
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 13.85
Tracking distinct RNA populations using efficient and reversible covalent chemistry 13.81
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 13.47
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 13.38
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines (mRNA-Seq) 13.16
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines 13.16
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 13.16
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 13.04
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 12.84
Hijacking of stress response machinery by oncogenes in acute leukaemia 12.84
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 12.82
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 12.72
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 12.69
Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs 12.59
Transcription elongation factors are in vivo-specific cancer dependencies in glioma 12.27
RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma 12.27
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 12.26
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 12.08
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 12.0
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 11.94
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 11.94
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 11.93
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 11.73
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 11.73
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 11.72
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq] 11.65
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 11.55
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 11.47
3’ Uridylation Expands miRNA Target Repertoire 11.46
Gene expression changes after LOC550643 silencing 11.28
Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [RNA-Seq] 11.25
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 11.25
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 11.25
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 11.24
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 11.23
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 11.13
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 11.09
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 11.07
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 11.07
Role of COP1 on MAP kinase transcriptional output in melanoma 10.96
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 10.79
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 10.77
Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a Colorectal Cancer Patient-derived Tumor Explant Model 10.7
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming 10.68
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies 10.67
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq] 10.67
Profiling in vivo Bone Lesion (IVBL) and Orthotopic tumors by Next Generation Sequencing 10.66
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 10.66
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 10.53
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 10.42
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 10.42
RNA-seq of exosomes identifies lncRNA profiles that distinguish early-stage esophageal squamous cell carcinoma (ESCC) from non-malignant esophagitis 10.4
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 10.24
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 10.18
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 10.16
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 10.13
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 10.11
Examining serotonergic neuron differentiation from human iPSCs 10.08
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 10.06
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites 9.99
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites (RNA-seq) 9.99
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 9.93
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 9.91
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 9.91
Endothelial gene expression analysis 9.86
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 9.86
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 9.83
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 9.43
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 9.43
RNA sequencing of human fibroblasts after SUPT4H1 siRNA treatment 9.42
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 9.18
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 9.18
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 9.13
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 8.77
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 8.71
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 8.69
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 8.6
Transcriptomic and gene ontology profiling of the human corneal cell types 8.49
RNA-sequencing of formalin fixed human primary melanoma tissue 8.4
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 8.39
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 8.34
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 8.32
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 8.32
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 8.28
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 8.28
Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain 8.28
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 8.26
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 8.14
Human T-cell lymphoblastic lymphoma samples and control thymuses 8.14
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 8.14
RNA-seq of naive and primed ES cells (NHSM) 8.11
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 8.05
RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d) 8.0
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 8.0
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 7.74
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 7.74
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 7.74
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 7.62
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 7.62
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 7.53
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 7.49
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 7.48
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 7.48
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 7.47
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 7.45
METTL3 and WTAP 7.36
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 7.29
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 7.29
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 7.29
Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2 7.24
RNA-seq analysis of uveal melanoma cells treated with FR900359 7.23
CUREfast: Accelerating research with families 7.21
Subtle asymmetry of gene expression in embryonic and foetal human brains 7.19
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 7.17
Single cell transcriptome of peritoneal cells 7.1
A sister of NANOG regulates genes expressed in pre-implantation human development 7.09
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 7.09
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 7.03
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 6.99
RNA-Seq analysis of neurons derived from induced pluripotent stem cells reprogrammed from dental pulp 6.94
Global epigenomic reconfiguration during mammalian brain development 6.94
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 6.93
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 6.87
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 6.86
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 6.86
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 6.86
RNA-seq of cancer cell lines treated with T-025 6.84
MeRIP-seq for heat shock in B-cell lymphoma cells 6.8
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 6.79
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 6.79
RNAseq of T-ALL upon long non coding rna purturbation 6.72
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 6.4
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 6.4
Pomalidomide inhibits PD-L1 induction to promote anti-tumor immunity 6.35
The evolution of N6-methyladenosine in primates 6.3
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 6.29
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 6.28
Transcriptome-wide identification of CELF2 functional targets in T cells 6.24
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 6.2
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 6.17
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 6.14
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 6.13
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 6.07
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 6.03
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 6.03
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 6.0
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 5.99
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 5.95
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 5.92
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 5.92
The Glioma-Infiltrating T Cell Receptor Repertoire 5.88
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 5.88
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 5.87
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 5.87
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 5.85
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 5.84
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 5.84
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 5.84
Potential signaling pathways and gene signatures associated with brain metastases in NSCLC patients 5.77
Repurposing of promoters and enhancers during mammalian evolution 5.75
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 5.75
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 5.75
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 5.74
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 5.7
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 5.7
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 5.65
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 5.65
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 5.64
miR941 overexpression experiment 5.63
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 5.62
HNF1A deficiency impairs β-cell fate, granule maturation and function 5.62
Cutaneous Immunoprofile of Three Spotted Fever Group Rickettsiosis 5.53
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 5.53
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 5.52
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 5.51
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 5.5
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 5.5
RNA-sequencing of human tendon after injury 5.5
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 5.45
RNAseq in Alzheimer's Disease patients 5.44
Global transcriptome analysis of HAP1 cells 5.44
The effect of PPARG inhibition on human angiomyolipoma cells 5.43
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 5.41
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 5.39
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 5.32
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 5.29
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 5.23
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 5.2
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 5.16
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 5.16
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 5.1
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 5.1
RNA editing in nascent RNA affects pre-mRNA splicing 5.01
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 4.81
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 4.81
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 4.81
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 4.81
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 4.81
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 4.8
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 4.78
ETV7 and interferon response 4.78
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 4.78
Total RNA-seq in ALL-SIL upon TLX1 knockdown 4.76
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 4.72
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 4.72
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 4.72
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 4.72
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 4.71
Transcriptional responses of melanoma cells to BRAF inhibition 4.68
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 4.67
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 4.67
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 4.66
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 4.61
Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy 4.58
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 4.56
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 4.52
Single Cell RNASeq profiling of stromal vascular fraction from Subcutaneous and visceral adipose tissue 4.5
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 4.47
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 4.44
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 4.44
Identification of long noncoding RNAs in T-ALL cell lines 4.42
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 4.4
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 4.39
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 4.39
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 4.36
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 4.35
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 4.33
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 4.33
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 4.33
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 4.31
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 4.31
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 4.29
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 4.28
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 4.16
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 4.15
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 4.09
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 4.03
RNA-seq data of small cell carcinoma of the bladder (SCCB) /urothelial carcinoma (Non-SCCB) clinical samples, and bladder-PARCB cell lines 3.93
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain 3.91
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 3.87
Clinker: visualizing fusion genes detected in RNA-seq data 3.86
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 3.75
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 3.75
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 3.74
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 3.71
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 3.71
Identification of differentially expressed circRNA in gallbladder cancer compared with matched normal tissue 3.66
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 3.65
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 3.62
RNA deep sequencing analysis of glioma stem cells(GSCs) and non-GSCs 3.58
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 3.58
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 3.58
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 3.55
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 3.47
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 3.47
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 3.47
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 3.38
nELAVL HITS-CLIP in Alzheimer's Disease patients 3.36
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 3.27
FGF2 regulation of gene expression in stable inducible Neurons 3.23
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 3.15
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 3.15
circRNA-sequencing 3.15
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 3.1
Leucegene: ALL sequencing 3.1
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells (longRNA-seq) 3.1
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells 3.1
Single-cell analysis of adult human ovary using 10X genomics 3.08
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 3.07
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 3.05
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 3.02
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 2.97
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 2.97
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 2.96
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 2.96
Loss of CREBBP results in gene expression repression in lymphoma cells 2.95
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 2.95
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 2.92
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 2.91
KSDM1b Role in Ewing Sarcoma 2.88
High-efficiency RNA-based reprogramming of human primary fibroblasts 2.84
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 2.8
RNA seq_PDX2_SHP099 2.77
Gene expression of collecting duct carcinoma of the kidney 2.76
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 2.75
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 2.74
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 2.74
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 2.74
High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues 2.71
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 2.65
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 2.65
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 2.55
Morphological and molecular characterization of human dermal lymphatic collectors 2.49
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 2.46
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 2.46
Analysis of human, chimpanzee, macaque and mouse tissue transcriptomes using Next Generation Sequencing 2.45
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 2.41
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 2.41
Epigenome regulation during epidermal lineage commitment [RNA-seq] 2.39
Gene expression profiling of patient's DCIS-IDC tandem lesions by RNA sequencing analysis 2.36
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 2.32
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 2.27
Modeling Trilateral Retinoblastoma using Human Embryonic Stem Cells 2.26
Transcriptome of EBV-infected gastric cancer cell lines 2.26
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia [RNA-seq] 2.24
RNA sequencing analysis of selumetinib-resistant CRC cells lines 2.22
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 2.19
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 2.17
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 2.15
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 2.14
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 2.04
SOX11 knockdown in B-ALL cell lines 1.83
Identification of expressed and conserved human non-coding RNAs 1.75
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 1.73
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 1.73
Gene expression analysis of breast cancer cell-lines 1.71
Gene expression and genome-wide location analysis of breast cancer cell-lines 1.71
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 1.69
Neonatal and adult human testis defined at the single-cell level 1.68
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 1.67
Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs 1.65
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 1.65
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 1.65
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 1.61
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.59
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.59
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 1.59
RNA-seq of SCLC PDX models treated with EP 1.55
Functional significance of the HIV-1 Tat signature amino acid residues 1.51
Antiviral and anti-inflammatory properties of novel anti-HIV candidate ABX464 promotes specifics RNA splicing while preserving cellular RNA integrity. 1.49
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 1.4
Disruption of GRIN2B impairs differentiation in human neurons 1.34
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 1.33
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 1.32
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 1.32
Gene expression profile of CRC-derived HILEC 1.31
Gene expression of thyroid cancer cell lines 1.31
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 1.31
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 1.29
Patient-derived xenograft platform for metastatic melanoma 1.27
Oncogenic roles of ARID5B in T-ALL 1.26
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 1.26
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 1.25
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 1.24
BMS-470539 on human synovial fibroblasts 1.23
Dissecting the single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancer [10x genomics] 1.22
The age and genomic integrity of neurons after cortical stroke in humans 1.21
The contribution of Alu exons to the human proteome 1.16
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 1.13
The DNA methylation landscape of human melanoma [RNA-Seq] 1.11
The DNA methylation landscape of human melanoma 1.11
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 1.09
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 1.06
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 1.05
Epigenome regulation during epidermal lineage commitment 1.04
Patient-derived xenograft platform for metastatic melanoma: a model for studying resistance to targeted therapy. 1.04
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 1.02
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.97
RNA-seq of Human neck of femur (NOF) fracture hip and osteoarthritic (OA) cartilage 0.97
Long noncoding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells 0.97
Random mono-allelic expression in MECP2-mutated cells 0.96
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 0.96
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 0.94
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.93
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 0.92
LINE-2 transposable elements are a source of functional human microRNAs and target sites 0.87
RNA sequencing of prostate cancer and normal tissue from African Americans and European Americans 0.86
Comparative Analysis of Cas9 Activators Across Multiple Species 0.84
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.83
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.83
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.8
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.78
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.78
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 0.78
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.75
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.72
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 0.65
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 0.65
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 0.62
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 0.62
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [Primary RNA-Seq] 0.61
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 0.61
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 0.6
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 0.56
RNA-Seq in PWS iPSC-derived neurons 0.55
Transcriptome analysis of fetal Klinefelter testis tissue samples compared to controls 0.55
Transcriptional profiling of healthy, eutopic and ectopic endometrial organoids 0.53
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.53
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 0.52
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 0.5
Engineering Patient-Specific Tissue Implants 0.45
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.45
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 0.37
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 0.36
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.34
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.34
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 0.34
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.32
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 0.31
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 0.3
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 0.3
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.23
Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny 0.23
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 0.21
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 0.16
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 0.15
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 0.13
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 0.13
JAK dependent survival of ALK- ALCL 0.02
Tissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases 0.02
RNA-Seq and expression data from human adipose tissue 0.02
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 0.01


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