Gene Query: OPTN

Dataset Description Geneva Score
Expression analysis of genes modulated after knock-down of lncRNA CHROME. 67.47
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 66.24
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 63.33
Transcriptional responses of human insulinoma cells to acute cytokine exposure 60.23
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 59.3
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 55.84
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 55.33
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 54.46
IDH3a KO RNA-seq 52.36
Crizotinib v. DMSO in SW480 cells 48.98
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 46.37
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 46.37
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 46.24
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 45.92
Overexpression of NFIB and YBX1 in MCF-7 cells 45.36
FOXD3 is a novel tumor suppressor in lung cancer 45.36
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 44.98
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 42.28
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns 39.02
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 38.49
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 34.45
Effect of Influenza virus infection on lncRNA expression in A549 cells 33.95
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 33.71
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 32.94
Lipid degradation promotes prostate cancer cell survival 32.88
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 32.87
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 32.87
Survival of pancreatic cancer cells lacking KRAS function 32.26
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 32.18
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 32.08
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 31.87
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 31.86
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 31.52
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 31.42
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 30.55
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 29.81
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 29.22
Neurofibroma 29.22
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 28.63
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 28.62
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 28.23
A role for ZNF598 in post-transcriptional gene regulation 27.92
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 27.87
Differetially expressed genes after hTR overexpression in U2OS cells 27.86
Genomic analysis of human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast 26.92
mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast 26.92
VAMP8 contributes to TRIM6-mediated type-I interferon antiviral response upon West Nile virus (WNV) infection 26.36
A549 cells and MSR-A549 cells 26.22
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 26.22
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 26.07
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 25.93
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 25.78
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 25.6
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 25.49
Genome-wide analysis of Dengue virus 2 infected cells 25.0
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 24.98
Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation 24.62
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 24.39
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 24.39
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 24.37
Global expression profiles in cardiac progenitor cells generated by ISX-9 24.37
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 24.09
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 23.37
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 23.31
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 23.09
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 23.02
Replicated transcriptome profiling of Normal and Cancerous Prostate Cells [RNA-Seq] 22.92
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 22.81
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations 22.64
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq] 22.64
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 22.62
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 22.62
Exploring ILF2 regulatory genes by next-generation sequencing 22.47
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 22.33
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 21.91
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 21.73
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 21.54
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 21.34
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 21.22
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 21.09
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 21.0
Hepatitis C virus functionally sequesters miR-122 21.0
Generation and functional characterization of MDSC-like cells 20.9
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 20.54
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 20.51
Paxillin regulates genomic networks in prostate cancer [LNCaP] 20.49
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 20.48
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 20.47
An integrative network biology analysis identifies miR-508-3p as the determinant and a prognosis biomarker of the mesenchymal subtype ovarian cancer 20.36
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 20.25
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 20.22
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 20.2
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 20.2
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 20.17
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 20.11
MYCi361 regulates MYC target genes 20.1
STRIPAK directs PP2A activity to promote oncogenic transformation 19.99
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 19.94
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 19.94
Gene induction by the USP6 oncogene in response to interferon 19.83
The cohesin complex prevents Myc-induced replication stress 19.8
Transcriptome profiling of Normal and Cancerous Prostate Cells 19.25
Maturation of human iNSCs 19.19
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 19.16
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 19.04
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 18.95
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 18.95
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 18.83
Transcriptomes of oxLDL exposed trained monocytes 18.79
oxLDL exposed trained monocytes 18.79
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 18.7
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 18.67
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 18.34
RNA-seq differential expression studies: more sequence, or more replication? 18.34
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 18.3
RNA-Seq study of Cell lines rendered resistant to idelalisib and ibrutinib 18.3
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 18.28
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 18.22
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 18.03
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 17.99
Tracking of dCas9-methyltransferase footprints 17.96
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 17.93
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 17.92
Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression 17.92
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 17.85
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 17.63
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 17.59
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 17.47
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 17.42
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 17.33
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 17.33
Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation 17.26
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (mRNA-Seq) 17.2
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 17.06
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 16.97
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 16.89
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 16.87
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 16.83
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 16.81
Transcriptome analysis of human airway epithelium infected by Human Bocavirus 1 16.72
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 16.59
Effect of from Human Umbilical Vein Endothelial Cells 16.48
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 16.43
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 16.43
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 16.28
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 16.28
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 16.26
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 16.26
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 16.25
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 16.25
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 16.2
UBC9 knockdown in bladder cancer T24 cell lines 16.2
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 16.17
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 16.15
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 16.15
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 16.13
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 16.13
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 16.09
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 15.97
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 15.96
Hypoxic transcriptome of SQ20B human head and neck cancer cells 15.94
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 15.91
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 15.86
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 15.81
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 15.78
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 15.77
The effect of PPARG inhibition on human angiomyolipoma cells 15.75
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 15.69
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 15.69
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 15.68
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 15.68
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 15.58
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 15.58
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 15.58
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 15.58
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 15.56
Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury 15.53
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 15.4
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 15.35
The ETS transcription factor ELF1 regulates a critical, broadly antiviral program distinct from the type I interferon response 15.35
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 15.26
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 15.26
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 15.1
Endothelial gene expression analysis 15.1
Human Adipocytes Regulate Gene Expression in Triple-negative Breast Cancer Assessed by NGS Sequencing 14.91
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 14.87
naive T cell heterogeneity after neonatal thymectomy 14.84
The regulartory role of ZCCHC24 in splicing machinery 14.83
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 14.74
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 14.73
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 14.69
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 14.65
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 14.6
Transcriptome wide analysis of classically and alternatively activated macrophages 14.59
Gene expression changes associated with resistance to tagraxofusp (SL-401) 14.57
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 14.55
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 14.45
Exploring the role of macroH2A1 in transcription regulation in IMR90 primary human lung fibroblasts with RNA-seq and ChIP-seq 14.44
RNA-seq from control and macroH2A1-depleted IMR90 primary human lung fibroblasts 14.44
Genetic-to-epigenetic Therapy for Pancreatic Cancer 14.39
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 14.32
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 14.27
Controlling for gene expression changes in transcription factor protein networks. 14.27
Control of prostate tumour growth by the long non-coding RNA GHSROS (LNCaP) 14.26
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 14.23
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion 14.19
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 14.15
RNA-seq analysis of control and Myc-induced U2OS cells 14.15
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 14.15
Developmental stage specific chromosome architecture in human erythroid cells 14.15
EWS-Fli and LNC regulated genes in comparison to GFP samples 14.08
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 14.04
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 13.86
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 13.86
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 13.84
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 13.82
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 13.8
High-efficiency RNA-based reprogramming of human primary fibroblasts 13.8
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 13.76
Effect of nuclear IL-33 on gene expression 13.7
Gene expression changes in human melanoma cell lines compared to primary melanocytes 13.68
WRN knockout effects upon gene expression in SW48 and OVK18 13.65
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 13.65
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 13.65
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 13.62
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 13.55
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 13.55
RNA splicing alteration on glioblastoma and normal neural stem cells 13.53
Expression data from miR340 overexpressing human A549 cells 13.51
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 13.51
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 13.48
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 13.48
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 13.42
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 13.42
RNA-seq analyisis of PUM2 knockout cells 13.41
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 13.38
CircRNAome diversity in human mature B-cells, T-cells and monocytes 13.36
RNA sequencing of GlyH-101-treated MCF-7 cell line 13.28
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 13.24
Functional role of SLIT2 and ROBO1 in trophoblasts 13.18
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 13.18
Trnascriptome analysis of HeLa cells infected with rTHOV-wt, -dML, -SW mutant or mock-treated 13.15
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 13.13
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 13.12
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 13.12
RNA-seq of overgrown interscapular adipose tissue with biallelic MFN2 mutations 13.11
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 13.11
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 13.09
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 12.99
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 12.93
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 12.93
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 12.92
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 12.92
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 12.91
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 12.9
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 12.84
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 12.84
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 12.8
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 12.8
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 12.76
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 12.75
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 12.74
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 12.73
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 12.71
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 12.69
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 12.62
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 12.62
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 12.6
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 12.59
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 12.55
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 12.55
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 12.53
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 12.53
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 12.52
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 12.48
Polarized B -cell functions 12.45
Glioblastoma stem cells infected by ZIKA virus 12.44
Expression by CD133+ cells isolated from the adult human exocrine pancreas 12.38
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes 12.31
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 12.3
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 12.29
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 12.26
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 12.26
tRNA modification landscape selectively controls mitochondrial translation efficiency in MERRF 12.25
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 12.22
mRNA Sequencing of Human PromoCells Using 3'-directed Digital Gene Expression (3'-DGE) Technique 12.19
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 12.16
An RNA-centric dissection of host complexes controlling flavivirus infection 12.16
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 12.12
RNA-seq of human aneuploid cell lines with Trisomy 21 12.12
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 12.06
Transcriptome Profiling of Influenza A Virus-infected Lung Epithelial (A549) Cells with Lariciresinol-4-β-D-glucopyranoside Treatment 12.04
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 12.04
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 12.04
The landscape of alternative splicing in aggressive prostate cancers 12.03
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 11.85
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 11.76
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 11.76
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 11.7
Genome-wide RNA-sequencing (RNA-seq) of benign and malignant prostate cell lines without and with androgen (R1881) stimulation. 11.69
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 11.62
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 11.57
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 11.49
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 11.44
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 11.43
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs 11.4
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs [RNA-seq] 11.4
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 11.35
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 11.34
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 11.32
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 11.25
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 11.25
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 11.22
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 11.22
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 11.1
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 11.08
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 11.06
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 11.06
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 10.94
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 10.94
The role of the Calcium-Sensing receptor in colorectal cancer 10.89
Transcriptomic profile of human embryonic renal corpuscles 10.87
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 10.84
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 10.83
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 10.8
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 10.8
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia 10.74
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 10.71
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 10.61
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 10.54
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 10.54
Transcriptional responses of melanoma cells to BRAF inhibition 10.46
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 10.38
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 10.38
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 10.37
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 10.37
The interplay between SOX4 and SMAD3 in the context of breast cancer 10.37
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression 10.36
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq] 10.36
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 10.29
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 10.26
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 10.21
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 10.19
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 10.02
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 10.02
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 9.94
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 9.94
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 9.74
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 9.72
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 9.63
RNA seq with AML (NB4) cells upon FTO inhibition 9.54
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 9.52
Transcriptome analyses of human pancreatic islets and pseudoislets 9.46
Human Treg NaCl stimulation 9.36
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 9.17
CD1c+ dendritic cell activation by Plasmodium falciparum-infected red blood cells 9.16
X-Ray induced DNA-Hydroxymethylation changes 9.15
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 9.13
ARID1A and ARID1B loss in HCT116 and TOV21G cells 8.92
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 8.8
Transcriptomic changes mediated by β-amyloid in human aortic endothelial cells (HAOEC) 8.62
RNA sequencing analysis of selumetinib-resistant CRC cells lines 8.59
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 8.57
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 8.55
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 8.55
Cell responses to dysregulated VZV-induced cell-cell fusion 8.35
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 8.25
Gene expression profiling of human iPS cell-derived podocytes and sorted human adult podocytes 8.23
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 8.19
RNA-seq analysis and shRNA screen of breast cancer 8.13
RNA-seq analysis of breast cancer 8.13
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells 8.09
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 7.98
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 7.98
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 7.95
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 7.9
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 7.84
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 7.76
The dynamic landscape of coding and non-coding RNAs in the innate immune response to microbial pathogens 7.66
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 7.57
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 7.2
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 7.2
RNA seq analysis of human Fetal and adult derived Enterospheres 7.14
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues 7.13
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 7.11
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 6.99
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 6.96
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 6.9
Selective expression of long non-coding RNAs in a breast cancer cell progression model 6.85
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 6.81
U2AF1 mutations alter splice site recognition in hematological malignancies 6.76
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 6.71
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 6.71
Epigenome regulation during epidermal lineage commitment 6.63
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 6.57
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 6.47
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 6.47
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 6.44
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 6.35
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 6.35
Transcriptome of activated human and mouse MAIT cells 6.29
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 6.22
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 6.11
CD74 role in transcription regulation 5.99
CD74 role in transcription regulation [RNA-seq] 5.99
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 5.85
RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) 5.81
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with colorectal carcinoma 5.64
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 5.63
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 5.43
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 5.35
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 5.34
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 5.33
AR-independent prostate cancer is sustained through FGF signaling 5.27
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 5.2
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 5.2
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 5.19
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 5.17
RNAseq of T-ALL upon long non coding rna purturbation 5.17
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 5.16
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 5.07
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 5.01
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 4.99
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 4.99
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 4.98
IMP3 regulated gene expression in breast cancer cells 4.93
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 4.88
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 4.87
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 4.7
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 4.58
Comparative Analysis of the Transcriptome of Latent Autoimmune Diabetes (LADA) Patients from Eastern China 4.56
6mer seed toxicity in tumour suppressive microRNAs 4.55
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 4.48
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 4.33
Macrophage Ad5f35 PhenoMap 4.17
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 4.15
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 4.15
Aneuploidy-induced cellular stresses limit autophagic degradation. 4.13
Impact on erythroid progenitor type on erythroid differntiation 4.07
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 3.91
SF3B1 Degron knockdown RNA-seq 3.85
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 3.76
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 3.47
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 3.32
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 3.14
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia. 3.09
Identification of long noncoding RNAs regulated by p53 2.99
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 2.98
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 2.79
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 2.79
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 2.73
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 2.71
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 2.68
Hepatocyte maturation 2.55
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 2.52
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 2.39
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 2.38
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 2.38
RNA-seq of CD33 KO and control HSPCs 2.38
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 2.27
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 2.19
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 2.11
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 2.08
Gene expression profiling of KSHV-infected periodontal ligament cells 2.06
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation [RNA-Seq] 1.93
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation 1.93
The mRNA expression analysis of psoriasis skin lesion mesenchymal stem cell 1.93
nELAVL HITS-CLIP in Alzheimer's Disease patients 1.92
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.89
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 1.88
Pluripotent stem cell models of Blau syndrome reveal an IFN-<gamma>-dependent inflammatory response in macrophages 1.83
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 1.81
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 1.81
Aging-associated patterns in the expression of human endogenous retroviruses 1.8
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 1.77
6mer seed toxicity in viral microRNAs 1.77
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 1.73
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 1.7
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 1.43
Transcriptomic analysis of human macrophages in 3D 1.41
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 1.41
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 1.31
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq] 1.27
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels 1.27
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 0.9
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 0.84
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 0.76
Vammin induces a highly efficient angiogenic response through VEGFR-2/NRP-1 and bypasses the regulatory function of VEGFR-1 0.63
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 0.6
Gene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing. 0.54
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 0.53
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 0.49
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.44
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 0.4
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [TAV] 0.35
mRNA sequencing of highly and lowly metastatic human colorectal cancer PDXs 0.21
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 0.14
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 0.1
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 0.08
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 0.04


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